Cléopatre Darleux (born 1 July 1989) is a French handball goalkeeper for Brest Bretagne Handball and the French national team.
She participated at the 2009 World Women's Handball Championship in China, winning a silver medal with the French team.
Darleux competed for France at the 2012 Summer Olympics and at the 2020 Summer Olympics (played in 2021 in Japan), where she helped the team win the gold medal.