|02 Aug 21||Santamarina ||-|| Instituto ACC|
|09 Aug 21||Barracas Central ||-|| Santamarina|
|14 Aug 21||Santamarina ||-|| Independiente Rivadavia|
|21 Aug 21||Atletico Rafaela ||-|| Santamarina|
|28 Aug 21||Santamarina ||-|| Guillermo Brown|
|24 Jul 21||Gimnasia y|| ||1 - 0|| ||Santamarina|
|17 Jul 21||Tristán Suárez|| ||2 - 1|| ||Santamarina|
|11 Jul 21||Santamarina|| ||0 - 2|| ||Ferro Carril|
|04 Jul 21||Deportivo Morón|| ||2 - 1|| ||Santamarina|
|27 Jun 21||Santamarina|| ||1 - 2|| ||Güemes|
Club y Biblioteca Ramón Santamarina, also known simply as Santamarina, is an Argentine football club from the city of Tandil, Buenos Aires Province. The team currently plays in Primera B Nacional, the tournament of second division of the Argentine Football Association. The club is named after Joaquin Ramón Cesareo Manuel Santamarina (1827-1904), an Argentine businessman.
The club has only played one season in the Argentine Primera. In 1985, it competed in the National championships, where it finished second in their group to qualify for the 2nd round where it was eliminated by Independiente 6–3 on aggregate.