|13 Oct 21||Chacaritas|| ||2 - 2|| ||América de|
|06 Oct 21||América de|| ||1 - 1|| ||Independiente Juniors|
|01 Oct 21||Guayaquil SC|| ||1 - 0|| ||América de|
|22 Sep 21||América de|| ||1 - 1|| ||Gualaceo|
|16 Sep 21||El Nacional|| ||1 - 4|| ||América de|
Club Deportivo América, commonly known as América de Quito, is a football club based in Quito, Ecuador. Once a top-level club in Ecuador that spent 22 seasons at that level, after being relegated in 1988, they have been relegated over the years to the country's third-level, Segunda Categoría; In 2018, they managed to return to the Serie A after 31 years. Even in spite of that long absence, they are still ranked 14th on Serie A's all-time list.