Anthony Tupou (born 1 March 1983) is a former professional rugby league footballer who played as a second-row and lockin the 2000s and 2010s. An Australian international and New South Wales State of Origin representative, he played for the Sydney Roosters, Cronulla-Sutherland Sharks and Newcastle Knights in the National Rugby League, while also having a stint in the Super League with the Wakefield Trinity Wildcats.
In 2017, Tupou returned to his hometown to play for the Newcastle Knights on a 1-year contract. He made his Knights début in round 5 of the 2017 season against his former club Cronulla. With a hip injury limiting his time at the Knights to only 4 games, he announced his retirement in September 2017.