Isaac Quaynor (born 15 January 2000) is a professional Australian rules footballer who plays for the Collingwood Football Club in the Australian Football League (AFL).
Quaynor was part of Collingwood's Next Generation Academy, described as "a superb decision-maker and a precise kick" who won the goal kicking test at the Draft Combine. The club drafted him to their Australian Football League (AFL) squad by Collingwood with the 13th draft pick of the 2018 AFL draft. As Collingwood's first pick of the draft, he wore the number 35 guernsey in his first season. Quaynor made his AFL debut in Collingwood's loss against Hawthorn in the 16th round of the 2019 AFL season.