Byron Murphy Jr. (born January 18, 1998) is an American football cornerback. He played college football at Washington.
Murphy was drafted by the Arizona Cardinals in the second round (33rd overall) of the 2019 NFL Draft. In week 10 against the Tampa Bay Buccaneers, Murphy recorded his first career interception off Jameis Winston in the 30–27 loss.
Murphy entered the 2021 season as a starting cornerback for the Cardinals. In Week 3 of the 2021 season, he had two interceptions, including a 29-yard pick-six in a 31-19 win over the Jaguars, earning NFC Defensive Player of the Week. He finished the season with 64 tackles and a team-leading 12 passes defensed and four interceptions.
On March 15, 2023, Murphy signed a two-year contract with the Minnesota Vikings.