17 Apr 21 | r01 | Houston Dyna | 2 - 1 | San Jose Ear |
17 Apr 21 | r01 | Seattle Soun | 4 - 0 | Minnesota Un |
17 Apr 21 | r01 | CF Montréal | 4 - 2 | Toronto FC |
17 Apr 21 | r01 | Orlando City | 0 - 0 | Atlanta Unit |
18 Apr 21 | r01 | New York Red | 1 - 2 | Sporting Kan |
18 Apr 21 | r01 | FC Dallas | 0 - 0 | Colorado Rap |
18 Apr 21 | r01 | DC United | 2 - 1 | New York Cit |
18 Apr 21 | r01 | Nashville SC | 2 - 2 | FC Cincinnat |
18 Apr 21 | r01 | Chicago Fire | 2 - 2 | New England |
18 Apr 21 | r01 | Los Angeles | 2 - 0 | Austin FC |