League
Club Friendlies
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Team 2021-2022 Scheduals
Sport
Soccer
League
Club Friendlies
Season
2021-2022
League Table
Club Friendlies
Season Badge
Season Poster
Team 2021-2022 SchedualsSport
SoccerLeague
Club Friendlies
Season
2021-2022
League TableEvent List
List
Poster| 08 Jan 20 |
r04  |  |  Ba Ria Vung | 3 - 1 | Long An FC |
| 08 Jan 20 |
r04 | | Can Tho FC | 3 - 0 | An Giang FC |
| 10 Jan 20 |
r04 | | Can Tho FC | 2 - 0 | Khanh Hoa FC |
| 12 Jan 20 |
r04 | | An Giang FC | 0 - 3 | Khanh Hoa FC |
| 14 Jan 20 |
r04 | | Ba Ria Vung | 2 - 1 | Binh Phuoc F |
| 16 Jan 20 |
r04 | | Binh Phuoc F | 1 - 1 | Long An FC |
| 16 Jan 20 |
r04 | | Ba Ria Vung | 3 - 0 | Pho Hien FC |
| 16 Jan 20 |
r04 | | Szombathelyi | 1 - 3 | Tiszakécske |
| 25 Jan 20 |
r04 | | VfL Oldenbur | 1 - 4 | Atlas Delmen |
| 17 Feb 20 |
r03 | | Real Monarch | 0 - 0 | Union Omaha |
| 19 Feb 20 |
r03 | | Birmingham L | 3 - 0 | Forward Madi |
| 19 Feb 20 |
r03 | | Hartford Ath | 5 - 1 | New England |
| 19 Feb 20 |
r03 | | Louisville C | 1 - 1 | Union Omaha |
| 20 Feb 20 |
r03 | | Samgurali | 0 - 2 | Jammerbugt |
| 22 Feb 20 |
r04 | | Can Tho FC | 2 - 1 | An Giang FC |
| 22 Feb 20 |
r03 | | Líšeň | 9 - 0 | Inter Bratis |
| 22 Feb 20 |
r03 | | Chikhura | 2 - 2 | Jammerbugt |
| 22 Feb 20 |
r03 | | Colorado Spr | 0 - 1 | Union Omaha |
| 22 Feb 20 |
r03 | | North Texas | 1 - 0 | El Paso Loco |
| 22 Feb 20 |
r03 | | New England | 1 - 0 | Hartford Ath |
| 22 Feb 20 |
r03 | | Swope Park R | 1 - 1 | Texas United |
| 22 Feb 20 |
r03 | | Richmond Kic | 0 - 1 | New York RB |
| 22 Feb 20 |
r03 | | Memphis 901 | 3 - 1 | Forward Madi |
| 23 Feb 20 |
r03 | | Charlotte In | 2 - 0 | Greenville T |
| 25 Feb 20 |
r03 | | North Texas | 1 - 3 | Tulsa Roughn |
| 25 Feb 20 |
r03 | | Louisville C | 4 - 0 | Forward Madi |
| 27 Feb 20 |
r03 | | North Texas | 1 - 0 | Swope Park R |
| 29 Feb 20 |
r03 | | Tormenta FC | 1 - 1 | Charleston B |
| 29 Feb 20 |
r03 | | FV Illertiss | 5 - 2 | FC Pipinsrie |
| 29 Feb 20 |
r03 | | New York RB | 3 - 0 | New England |
| 29 Feb 20 |
r03 | | North Caroli | 1 - 2 | Greenville T |
| 29 Feb 20 |
r03 | | Saint Louis | 2 - 1 | Forward Madi |
| 07 Mar 20 |
r03 | | Bremer SV | 0 - 6 | Oldenburg |
| 07 Mar 20 |
r03 | | Pittsburgh R | 0 - 0 | Toronto FC I |
| 01 Jul 20 |
r04 | | SV TEC | 4 - 2 | Sparta Nijke |
| 15 Jul 20 |
r03 | | MTK Hungaria | 5 - 1 | III Kerület |
| 16 Jul 20 |
r03 | | SC Cambuur | 4 - 1 | Harkemase Bo |
| 17 Jul 20 |
r04 | | HVV Hollandi | 3 - 4 | Jong Volenda |
| 18 Jul 20 |
r03 | | Stade Plaben | P - P | Brest |
| 18 Jul 20 |
r04 | | III Kerület | 1 - 3 | Budaörs |
| 18 Jul 20 |
r04 | | Spartak Varn | P - P | Sozopol |
| 18 Jul 20 |
r03 | | FC Chambly | 4 - 0 | AS Beauvais |
| 18 Jul 20 |
r03 | | Radomlje | 0 - 4 | MTK Hungaria |
| 21 Jul 20 |
r03 | | De Treffers | 1 - 4 | De Graafscha |
| 22 Jul 20 |
r04 | | Lokomotiv Go | P - P | Spartak Varn |
| 24 Jul 20 |
r04 | | First Vienna | 6 - 3 | Wiener Neust |
| 24 Jul 20 |
r03 | | Aviron Bayon | 1 - 2 | Ajaccio |
| 25 Jul 20 |
r04 | | FC Lisse | 0 - 3 | Amsterdamsch |
| 25 Jul 20 |
r04 | | Sparta Nijke | 1 - 2 | VV Noordwijk |
| 25 Jul 20 |
r03 | | FC Den Bosch | 5 - 0 | De Treffers |
| 25 Jul 20 |
r04 | | VVSB | 2 - 2 | Rijnsburgse |
| 25 Jul 20 |
r03 | | Radomlje | 0 - 4 | Budafoki MTE |
| 26 Jul 20 |
r03 | | RKVV EVV | 0 - 2 | VVV-Venlo |
| 26 Jul 20 |
r04 | | Szolnok | 1 - 1 | Kecskeméti |
| 28 Jul 20 |
r03 | | NAC Breda | 1 - 0 | Sparta Nijke |
| 28 Jul 20 |
r03 | | De Treffers | 0 - 1 | TOP Oss |
| 31 Jul 20 |
r01 | | PSV Eindhove | P - P | VV UNA |
| 01 Aug 20 |
r03 | | Olympique Ma | P - P | Stade de Rei |
| 01 Aug 20 |
r03 | | Helmond Spor | 2 - 0 | VV UNA |
| 01 Aug 20 |
r03 | | Bremer SV | 0 - 4 | Viktoria Ber |
| 01 Aug 20 |
r04 | | Harkemase Bo | 1 - 0 | HHC Hardenbe |
| 01 Aug 20 |
r03 | | VV ASWH | 1 - 0 | FC Dordrecht |
| 01 Aug 20 |
r04 | | Kozakken Boy | 3 - 5 | Sparta Nijke |
| 01 Aug 20 |
r04 | | USV Hercules | 1 - 0 | De Treffers |
| 01 Aug 20 |
r03 | | FCSR Haguena | P - P | Strasbourg |
| 02 Aug 20 |
r03 | | Celje | 4 - 0 | Radomlje |
| 02 Aug 20 |
r03 | | Hannover II | P - P | Bremer SV |
| 04 Aug 20 |
r03 | | US Saint-Ome | 0 - 3 | USL Dunkerqu |
| 04 Aug 20 |
r04 | | RKVV Westlan | 1 - 3 | SVV Scheveni |
| 04 Aug 20 |
r03 | | De Treffers | 0 - 2 | NEC Nijmegen |
| 04 Aug 20 |
r04 | | RKVV DEM | 2 - 2 | Koninklijke |
| 05 Aug 20 |
r04 | | Pandurii | 0 - 4 | FC U Craiova |
| 05 Aug 20 |
r03 | | Caen | 1 - 1 | Vannes OC |
| 05 Aug 20 |
r03 | | Bourges 18 | P - P | Auxerre |
| 05 Aug 20 |
r03 | | RKVV EVV | 2 - 5 | Helmond Spor |
| 07 Aug 20 |
r03 | | FC Twente | 3 - 1 | Excelsior 31 |
| 08 Aug 20 |
r04 | | Sparta Nijke | 2 - 2 | Amsterdamsch |
| 08 Aug 20 |
r03 | | Helmond Spor | 3 - 0 | SV OSS 20 |
| 08 Aug 20 |
r04 | | FC Lisse | 3 - 7 | Rijnsburgse |
| 08 Aug 20 |
r03 | | Willem II | P - P | IJsselmeervo |
| 08 Aug 20 |
r04 | | Atlas Delmen | 2 - 3 | VfL Oldenbur |
| 08 Aug 20 |
r03 | | Quick Boys | 0 - 1 | SC Telstar |
| 08 Aug 20 |
r04 | | Les Herbiers | 2 - 0 | Voltigeurs d |
| 08 Aug 20 |
r04 | | De Treffers | P - P | GVV Unitas |
| 09 Aug 20 |
r03 | | Atlas Delmen | 1 - 1 | Bremer SV |
| 09 Aug 20 |
r03 | | SO Romoranti | 0 - 2 | Chateauroux |
| 11 Aug 20 |
r04 | | GVVV | 2 - 0 | VVOG |
| 11 Aug 20 |
r03 | | VV UNA | 1 - 3 | NEC Nijmegen |
| 11 Aug 20 |
r03 | | SC Telstar | 6 - 1 | HVV Hollandi |
| 11 Aug 20 |
r04 | | BVV Barendre | 1 - 1 | Excelsior |
| 11 Aug 20 |
r04 | | IJsselmeervo | 0 - 1 | USV Hercules |
| 11 Aug 20 |
r03 | | SV TEC | 1 - 0 | FC Den Bosch |
| 12 Aug 20 |
r03 | | FC Olexandri | 3 - 1 | Kryvbas Kryv |
| 15 Aug 20 |
r03 | | Górnik Polk | 1 - 5 | Miedz Legnic |
| 15 Aug 20 |
r03 | | Jammerbugt | 2 - 0 | Thisted |
| 15 Aug 20 |
r03 | | VV Gemert | 1 - 1 | Helmond Spor |
| 15 Aug 20 |
r04 | | Kozakken Boy | 5 - 1 | VV Capelle |
| 15 Aug 20 |
r03 | | Warrenpoint | P - P | Bangor |
| 15 Aug 20 |
r03 | | SSV Jeddeloh | 4 - 2 | VfL Oldenbur |
| 15 Aug 20 |
r03 | | FC Pipinsrie | 2 - 2 | Eichstätt |
| 15 Aug 20 |
r03 | | Pau FC | 0 - 2 | US Colomiers |
| 18 Aug 20 |
r05 | | Vendée Font | 0 - 1 | Stade Poitev |
| 18 Aug 20 |
r04 | | Rijnsburgse | 1 - 0 | HSV ODIN 59 |
| 18 Aug 20 |
r05 | | BVV Barendre | - | VV Dongen |
| 18 Aug 20 |
r04 | | Quick Boys | 3 - 0 | Ter Leede |
| 18 Aug 20 |
r04 | | GVVV | 3 - 1 | Blauw Geel 3 |
| 21 Aug 20 |
r03 | | Servette | 8 - 0 | Thonon Évia |
| 22 Aug 20 |
r03 | | Bełchatów | 1 - 1 | Skra Często |
| 22 Aug 20 |
r04 | | De Treffers | 2 - 0 | VV UNA |
| 22 Aug 20 |
r03 | | Vendsyssel F | 1 - 0 | Jammerbugt |
| 22 Aug 20 |
r05 | | Rijnsburgse | 3 - 0 | USV Hercules |
| 22 Aug 20 |
r05 | | VV Katwijk | 0 - 0 | FC Eindhoven |
| 22 Aug 20 |
r05 | | Sparta Nijke | 2 - 2 | GVVV |
| 22 Aug 20 |
r05 | | IJsselmeervo | - | SC Telstar |
| 22 Aug 20 |
r05 | | Amsterdamsch | 1 - 0 | IJsselmeervo |
| 22 Aug 20 |
r05 | | Jong AZ | - | Amsterdamsch |
| 23 Aug 20 |
r04 | | VfL Oldenbur | 2 - 2 | Bremer SV |
| 25 Aug 20 |
r03 | | SSV Jeddeloh | P - P | VfL Oldenbur |
| 25 Aug 20 |
r04 | | BVV Barendre | 1 - 2 | VV ASWH |
| 25 Aug 20 |
r04 | | VV Noordwijk | 1 - 1 | HVV Hollandi |
| 25 Aug 20 |
r04 | | VV DOVO | 3 - 3 | SV Spakenbur |
| 25 Aug 20 |
r04 | | Koninklijke | 2 - 1 | Ter Leede |
| 28 Aug 20 |
r05 | | Bangor | 1 - 2 | Ards |
| 29 Aug 20 |
r03 | | VfR Garching | 0 - 1 | FC Pipinsrie |
| 29 Aug 20 |
r04 | | Kozakken Boy | 1 - 3 | Jong Sparta |
| 29 Aug 20 |
r05 | | Rijnsburgse | 3 - 0 | Jong Volenda |
| 29 Aug 20 |
r05 | | Central Spor | 2 - 0 | Campinense |
| 30 Aug 20 |
r03 | | FC Olexandri | P - P | Kryvbas Kryv |
| 01 Sep 20 |
r05 | | SC Telstar | - | Rijnsburgse |
| 11 Sep 20 |
r03 | | SC Eltersdor | 0 - 0 | SpVgg Greuth |
| 11 Sep 20 |
r03 | | Warrenpoint | P - P | Armagh City |
| 01 Jan 21 |
r04 | | Khanh Hoa FC | 2 - 3 | Da Nang |
| 01 Jan 21 |
r04 | | Binh Duong | 2 - 1 | Nam Dinh |
| 02 Jan 21 |
r04 | | Ho Chi Minh | 2 - 1 | Ha Noi |
| 02 Jan 21 |
r04 | | Sai Gon | 1 - 1 | Binh Dinh |
| 03 Jan 21 |
r04 | | Nam Dinh | 1 - 1 | Hoang Anh Gi |
| 03 Jan 21 |
r04 | | Binh Duong | 0 - 0 | Khanh Hoa FC |
| 05 Jan 21 |
r04 | | Hoang Anh Gi | 2 - 1 | Khanh Hoa FC |
| 05 Jan 21 |
r04 | | Binh Duong | 0 - 0 | Da Nang |
| 07 Jan 21 |
r04 | | Sai Gon | 2 - 2 | Da Nang |
| 09 Jan 21 |
r04 | | Soroksár | 1 - 0 | Dorog |
| 09 Jan 21 |
r04 | | Laredo | 1 - 0 | Rayo Cantabr |
| 15 Jan 21 |
r04 | | Litex Lovech | 1 - 0 | Lokomotiv Go |
| 16 Jan 21 |
r04 | | Soroksár | 0 - 4 | Pécs |
| 16 Jan 21 |
r04 | | Akademija Pa | 2 - 1 | Borec |
| 19 Jan 21 |
r04 | | Pirin Blagoe | 5 - 1 | Marek Dupnit |
| 20 Jan 21 |
r04 | | Soroksár | 1 - 2 | Vasas |
| 20 Jan 21 |
r04 | | Sesvete | 2 - 0 | Kustošija |
| 20 Jan 21 |
r04 | | Hebar Pazard | 3 - 0 | Maritsa Plov |
| 20 Jan 21 |
r04 | | Borec | 1 - 1 | Rabotnichki |
| 20 Jan 21 |
r04 | | Opatija | 2 - 3 | Hrvatski Dra |
| 21 Jan 21 |
r04 | | Belasica | 2 - 3 | Tikveš |
| 21 Jan 21 |
r04 | | CSM Reşiţa | 3 - 1 | FC Politehni |
| 21 Jan 21 |
r04 | | Strumska Sla | 1 - 2 | Ludogorets R |
| 22 Jan 21 |
r04 | | Petrolul | 2 - 1 | Dunarea Cala |
| 23 Jan 21 |
r04 | | Gyirmót | 1 - 0 | Csákvár |
| 23 Jan 21 |
r04 | | Sesvete | 3 - 5 | Dubrava |
| 23 Jan 21 |
r04 | | Litex Lovech | 2 - 0 | Yantra Gabro |
| 23 Jan 21 |
r04 | | Lokomotiv So | 0 - 0 | Lokomotiv Go |
| 23 Jan 21 |
r04 | | Rabotnichki | 2 - 0 | Teteks |
| 23 Jan 21 |
r04 | | Opatija | 2 - 1 | Kustošija |
| 23 Jan 21 |
r04 | | FUS Rabat | 1 - 3 | Chabab Moham |
| 24 Jan 21 |
r04 | | Szombathelyi | 1 - 1 | Szolnok |
| 26 Jan 21 |
r04 | | LDU Quito | 2 - 0 | Fenix |
| 26 Jan 21 |
r04 | | Struga | 3 - 2 | Pelister |
| 27 Jan 21 |
r04 | | Rapid Bucure | 1 - 0 | Universitate |
| 27 Jan 21 |
r04 | | Dubrava | 2 - 0 | Hrvatski Dra |
| 27 Jan 21 |
r04 | | Renova | 3 - 3 | Rabotnichki |
| 27 Jan 21 |
r04 | | Kolubara | 5 - 1 | Žarkovo |
| 27 Jan 21 |
r04 | | Borec | 2 - 0 | Teteks |
| 27 Jan 21 |
r04 | | Opatija | 2 - 3 | Sesvete |
| 28 Jan 21 |
r04 | | CSA Steaua B | 4 - 1 | Universitate |
| 28 Jan 21 |
r04 | | Pelister | 2 - 2 | FK Jagodina |
| 30 Jan 21 |
r04 | | Emelec | 0 - 0 | Técnico Uni |
| 30 Jan 21 |
r04 | | Teteks | 1 - 3 | FK Jagodina |
| 30 Jan 21 |
r04 | | Ripensia Tim | - | Pandurii |
| 30 Jan 21 |
r04 | | Ludogorets R | 1 - 1 | Sportist Svo |
| 30 Jan 21 |
r04 | | Hajduk Split | 3 - 2 | Dugopolje |
| 30 Jan 21 |
r04 | | Kustošija | 3 - 0 | Hrvatski Dra |
| 30 Jan 21 |
r04 | | FC Yessentuk | 1 - 2 | FC Mashuk-KM |
| 30 Jan 21 |
r04 | | Struga | 0 - 0 | Rabotnichki |
| 30 Jan 21 |
r04 | | Lokomotiv So | - | Strumska Sla |
| 30 Jan 21 |
r04 | | Avangard Kur | - | FC Chernomor |
| 30 Jan 21 |
r04 | | Belasica | 0 - 0 | Radnički Sr |
| 30 Jan 21 |
r04 | | Dubrava | 5 - 1 | Opatija |
| 30 Jan 21 |
r04 | | VMFD Zalgiri | 4 - 2 | Nevėžis |
| 31 Jan 21 |
r04 | | Hrvatski Dra | 2 - 0 | Sesvete |
| 31 Jan 21 |
r04 | | FC Druzhba M | 0 - 5 | FC SKA Rosto |
| 31 Jan 21 |
r04 | | Dubrava | 1 - 3 | Kustošija |
| 01 Feb 21 |
r04 | | Manta | 2 - 4 | Barcelona SC |
| 01 Feb 21 |
r04 | | Peñarol | - | Belgrano |
| 01 Feb 21 |
r04 | | Adelaide Oly | - | Adelaide Com |
| 01 Feb 21 |
r04 | | Mt Druitt To | - | Blacktown Ci |
| 01 Feb 21 |
r04 | | Queensland L | - | Sunshine Coa |
| 01 Feb 21 |
r04 | | Struga | 3 - 1 | Teteks |
| 03 Feb 21 |
r04 | | Rabotnichki | 1 - 1 | Pelister |
| 03 Feb 21 |
r04 | | Litex Lovech | 0 - 0 | Septemvri So |
| 03 Feb 21 |
r04 | | Kolubara | 3 - 0 | Radnički 19 |
| 04 Feb 21 |
r04 | | Merani Martv | 5 - 2 | Dinamo Zugdi |
| 04 Feb 21 |
r04 | | Ripensia Tim | 1 - 2 | CSM Reşiţa |
| 05 Feb 21 |
r04 | | Guayaquil Ci | 0 - 1 | Barcelona SC |
| 05 Feb 21 |
r04 | | Dunarea Cala | 2 - 2 | Rapid Bucure |
| 05 Feb 21 |
r04 | | Spartak Varn | 1 - 2 | Strumska Sla |
| 06 Feb 21 |
r04 | | FK Suduva | 1 - 1 | Hegelmann Li |
| 06 Feb 21 |
r04 | | Borac Cacak | 1 - 0 | FK Zemun |
| 06 Feb 21 |
r04 | | FC U Craiova | 2 - 1 | CSM Reşiţa |
| 06 Feb 21 |
r04 | | Rabotnichki | 1 - 1 | Tikveš |
| 06 Feb 21 |
r04 | | Belasica | 1 - 1 | Bregalnica � |
| 06 Feb 21 |
r04 | | VMFD Zalgiri | - | FK Riteriai |
| 08 Feb 21 |
r04 | | FK Sarajevo | 1 - 0 | Triglav Kran |
| 10 Feb 21 |
r04 | | FC Yessentuk | 1 - 3 | PFC Spartak |
| 10 Feb 21 |
r04 | | FC Dnepr Mog | 6 - 0 | FC Orsha |
| 10 Feb 21 |
r04 | | FC Chernomor | 4 - 3 | FC Volga Uly |
| 10 Feb 21 |
r04 | | Pandurii | 1 - 1 | Slatina |
| 10 Feb 21 |
r04 | | FC Mashuk-KM | 0 - 1 | Anzhi Makhac |
| 10 Feb 21 |
r04 | | Radnički 19 | 3 - 0 | OFK Beograd |
| 13 Feb 21 |
r04 | | Concordia | 1 - 0 | Metaloglobus |
| 13 Feb 21 |
r04 | | FC Yessentuk | 0 - 4 | FC Legion Dy |
| 13 Feb 21 |
r04 | | CS Mioveni | 1 - 2 | Rapid Bucure |
| 13 Feb 21 |
r04 | | FK Suduva | 1 - 1 | Banga Gargž |
| 13 Feb 21 |
r04 | | Pandurii | - | FC U Craiova |
| 13 Feb 21 |
r04 | | VMFD Zalgiri | 3 - 0 | FK Riteriai |
| 13 Feb 21 |
r04 | | Treze | 1 - 2 | Globo |
| 14 Feb 21 |
r04 | | FC Chernomor | - | FC Sokol Sar |
| 14 Feb 21 |
r04 | | FC Kuban-Hol | 1 - 0 | FC Kaluga |
| 15 Feb 21 |
r04 | | Barcelona SC | 1 - 1 | 9 de Octubre |
| 16 Feb 21 |
r04 | | PFC Spartak | 2 - 5 | FC Legion Dy |
| 17 Feb 21 |
r04 | | FC Zenit-Izh | 1 - 2 | FC Zvezda Pe |
| 18 Feb 21 |
r04 | | Teteks | 4 - 0 | Bregalnica � |
| 18 Feb 21 |
r04 | | Locomotive T | 1 - 4 | Linense |
| 18 Feb 21 |
r04 | | Treze | 1 - 3 | America RN |
| 20 Feb 21 |
r04 | | FC Yessentuk | 4 - 2 | FC Tuapse |
| 20 Feb 21 |
r04 | | FC Ryazan | 3 - 1 | FC Kvant Obn |
| 20 Feb 21 |
r04 | | Mjoendalen | - | Sandefjord |
| 23 Feb 21 |
r04 | | FC Mashuk-KM | 2 - 0 | FC Tuapse |
| 24 Feb 21 |
r04 | | FC Kuban-Hol | - | KAMAZ Nabere |
| 24 Feb 21 |
r04 | | FC Ryazan | - | FC Metallurg |
| 25 Feb 21 |
r04 | | FC Novosibir | 2 - 4 | FC Chernomor |
| 25 Feb 21 |
r04 | | FC Zvezda Pe | 0 - 3 | FC Zenit-Izh |
| 25 Feb 21 |
r04 | | FC Yessentuk | 1 - 4 | FC Salyut Be |
| 25 Feb 21 |
r04 | | Puerto Cabel | 1 - 2 | Hermanos Col |
| 26 Feb 21 |
r04 | | FC Yessentuk | 4 - 2 | FC Tuapse |
| 26 Feb 21 |
r04 | | Extremadura | 2 - 2 | Salamanca UD |
| 26 Feb 21 |
r04 | | Universidad | 1 - 1 | Puerto Cabel |
| 26 Feb 21 |
r04 | | Deportivo La | 1 - 0 | Portuguesa F |
| 27 Feb 21 |
r04 | | FC Sokol Sar | 1 - 2 | PFC Kuban Kr |
| 27 Feb 21 |
r04 | | FC Sokol Sar | - | FC Kuban-Hol |
| 27 Feb 21 |
r04 | | Deportivo La | 1 - 1 | Puerto Cabel |
| 28 Feb 21 |
r04 | | FK Suduva | 1 - 0 | Nevėžis |
| 28 Feb 21 |
r04 | | FC Kuban-Hol | 2 - 2 | FC Novosibir |
| 28 Feb 21 |
r04 | | Portuguesa F | 1 - 0 | Universidad |
| 28 Feb 21 |
r04 | | Deportivo La | 2 - 2 | Hermanos Col |
| 01 Mar 21 |
r04 | | FC Yessentuk | 1 - 3 | FC Mashuk-KM |
| 01 Mar 21 |
r04 | | PFC Spartak | 1 - 0 | FC Salyut Be |
| 03 Mar 21 |
r04 | | FC Kuban-Hol | 1 - 1 | FC Luki-Ener |
| 05 Mar 21 |
r04 | | FC Novosibir | 4 - 1 | FC Kaluga |
| 08 Mar 21 |
r04 | | FC Novosibir | 3 - 1 | Avangard Kur |
| 09 Mar 21 |
r04 | | FC Kaluga | 0 - 1 | FC Luki-Ener |
| 12 Mar 21 |
r04 | | FC Yessentuk | - | FC Salyut Be |
| 20 Mar 21 |
r04 | | FUS Rabat | 1 - 0 | IR Tanger |
| 20 Mar 21 |
r04 | | Campinense | 1 - 0 | Central Spor |
| 21 Mar 21 |
r04 | | Saturn Ramen | 0 - 1 | FC Zvezda Pe |
| 22 Mar 21 |
r04 | | Saturn Ramen | 0 - 3 | FC Ryazan |
| 23 Mar 21 |
r04 | | Torns IF | 4 - 0 | IFK Malmö |
| 24 Mar 21 |
r04 | | Central Spor | - | Campinense |
| 27 Mar 21 |
r04 | | Alcoyano | 2 - 2 | Eldense |
| 27 Mar 21 |
r04 | | FC Novosibir | 3 - 1 | FC Nosta Nov |
| 28 Mar 21 |
r02 | | Denizlispor | 2 - 3 | Altay |
| 07 Apr 21 |
r03 | | Inter Miami | 1 - 0 | Miami FC |
| 07 Apr 21 |
r03 | | New England | - | Seattle Soun |
| 07 Apr 21 |
r03 | | Chicago Fire | 2 - 0 | Forward Madi |
| 07 Apr 21 |
r03 | | New England | 2 - 1 | LA Galaxy II |
| 07 Apr 21 |
r03 | | FC Dallas | 3 - 3 | Austin FC |
| 08 Apr 21 |
r03 | | SD Amorebiet | - | Eibar |
| 08 Apr 21 |
r03 | | CF Montréal | 0 - 2 | Tormenta FC |
| 09 Apr 21 |
r03 | | San Jose Ear | 3 - 2 | Oakland Root |
| 09 Apr 21 |
r03 | | Orlando City | 3 - 2 | Minnesota Un |
| 09 Apr 21 |
r03 | | Austin Bold | 1 - 1 | Rio Grande V |
| 10 Apr 21 |
r03 | | Birmingham L | - | Nashville SC |
| 10 Apr 21 |
r03 | | FC Lahti | 2 - 1 | KTP |
| 10 Apr 21 |
r03 | | EIF | - | Mariehamn |
| 10 Apr 21 |
r03 | | TPS | 0 - 1 | HIFK Fotboll |
| 10 Apr 21 |
r03 | | Vancouver Wh | 3 - 2 | Chicago Fire |
| 10 Apr 21 |
r03 | | Loudoun Unit | - | Richmond Kic |
| 10 Apr 21 |
r03 | | New York Cit | 2 - 0 | Hartford Ath |
| 10 Apr 21 |
r03 | | New York Red | 1 - 1 | DC United |
| 10 Apr 21 |
r03 | | Indy Eleven | - | Vancouver Wh |
| 10 Apr 21 |
r03 | | Pittsburgh R | 2 - 1 | FC Cincinnat |
| 10 Apr 21 |
r03 | | Los Angeles | 3 - 3 | New England |
| 10 Apr 21 |
r03 | | New Mexico U | 4 - 2 | Colorado Spr |
| 10 Apr 21 |
r03 | | OKC Energy | 3 - 1 | North Texas |
| 10 Apr 21 |
r03 | | FC Dallas | 3 - 0 | Houston Dyna |
| 10 Apr 21 |
r03 | | Las Vegas Li | P - P | California U |
| 10 Apr 21 |
r03 | | Austin FC | 5 - 1 | San Antonio |
| 10 Apr 21 |
r03 | | Seattle Soun | 1 - 0 | San Diego Lo |
| 11 Apr 21 |
r03 | | Austin FC | - | Louisville C |
| 11 Apr 21 |
r03 | | Inter Miami | - | Miami FC |
| 11 Apr 21 |
r03 | | CF Montréal | 5 - 1 | Tampa Bay Ro |
| 11 Apr 21 |
r03 | | Austin FC | 3 - 2 | Rio Grande V |
| 11 Apr 21 |
r03 | | Seattle Soun | - | LA Galaxy II |
| 11 Apr 21 |
r03 | | Seattle Soun | 1 - 0 | San Diego Lo |
| 11 Apr 21 |
r03 | | Louisville C | 4 - 2 | Greenville T |
| 11 Apr 21 |
r03 | | El Paso Loco | 3 - 1 | Colorado Spr |
| 11 Apr 21 |
r03 | | Inter Miami | - | Toronto FC |
| 12 Apr 21 |
r03 | | Sirius | 6 - 0 | Brommapojkar |
| 12 Apr 21 |
r03 | | FC Haka | 1 - 2 | SJK Seinajok |
| 13 Apr 21 |
r03 | | HJK Helsinki | 4 - 0 | AC Oulu |
| 15 Apr 21 |
r03 | | OKC Energy | 0 - 1 | Austin Bold |
| 16 Apr 21 |
r03 | | Hartford Ath | 2 - 1 | New York RB |
| 16 Apr 21 |
r03 | | Charleston B | 2 - 1 | North Caroli |
| 16 Apr 21 |
r03 | | El Paso Loco | 1 - 3 | North Texas |
| 17 Apr 21 |
r03 | | Phoenix Risi | - | Colorado Spr |
| 17 Apr 21 |
r03 | | El Paso Loco | - | FC Dallas |
| 17 Apr 21 |
r03 | | Rosenborg | 3 - 0 | Raufoss |
| 17 Apr 21 |
r03 | | Vaalerenga | - | KFUM |
| 17 Apr 21 |
r03 | | Mjoendalen | 5 - 2 | Grorud IL |
| 17 Apr 21 |
r03 | | Start | 2 - 3 | Bryne |
| 17 Apr 21 |
r03 | | Gnistan | 0 - 1 | HIFK Fotboll |
| 17 Apr 21 |
r03 | | FC Haka | - | KTP |
| 17 Apr 21 |
r03 | | Molde | 2 - 1 | Stjørdals-B |
| 17 Apr 21 |
r03 | | Sogndal | 4 - 1 | Brann |
| 17 Apr 21 |
r03 | | Kristiansund | 0 - 3 | Ranheim |
| 17 Apr 21 |
r03 | | Odd Ballklub | 0 - 0 | Sandefjord |
| 17 Apr 21 |
r03 | | Viking | 1 - 1 | ASANE FOTBAL |
| 17 Apr 21 |
r03 | | SJK Seinajok | 3 - 0 | KPV |
| 17 Apr 21 |
r03 | | Inter Turku | 1 - 0 | Mariehamn |
| 17 Apr 21 |
r03 | | JERV | 3 - 2 | Sandnes |
| 17 Apr 21 |
r03 | | HJK Helsinki | 1 - 2 | FC Lahti |
| 17 Apr 21 |
r03 | | North Texas | 0 - 4 | El Paso Loco |
| 17 Apr 21 |
r03 | | New Mexico U | 3 - 1 | FC Tucson |
| 17 Apr 21 |
r03 | | Indy Eleven | 3 - 0 | Forward Madi |
| 17 Apr 21 |
r03 | | Greenville T | 2 - 1 | Charlotte In |
| 17 Apr 21 |
r03 | | Orange Count | 1 - 3 | LA Galaxy II |
| 17 Apr 21 |
r03 | | Tulsa Roughn | 1 - 1 | Austin Bold |
| 17 Apr 21 |
r03 | | Louisville C | 2 - 0 | Pittsburgh R |
| 17 Apr 21 |
r03 | | Union Omaha | 2 - 1 | Swope Park R |
| 17 Apr 21 |
r03 | | Birmingham L | 4 - 1 | Chattanooga |
| 17 Apr 21 |
r03 | | Richmond Kic | - | Loudoun Unit |
| 18 Apr 21 |
r03 | | Bodoe/Glimt | 1 - 1 | Tromso |
| 18 Apr 21 |
r03 | | RoPS | 1 - 2 | AC Oulu |
| 18 Apr 21 |
r03 | | Sarpsborg 08 | 2 - 2 | Stabaek |
| 18 Apr 21 |
r03 | | Stroemsgodse | 2 - 3 | Lillestroem |
| 18 Apr 21 |
r03 | | Fredrikstad | 4 - 1 | Ull Kisa |
| 18 Apr 21 |
r03 | | Hamarkamerat | 2 - 0 | Strommen |
| 21 Apr 21 |
r03 | | Mjoendalen | 4 - 0 | Sandefjord |
| 21 Apr 21 |
r03 | | Aalesund | 1 - 0 | Sogndal |
| 21 Apr 21 |
r03 | | Odd Ballklub | 1 - 1 | JERV |
| 21 Apr 21 |
r03 | | Vaalerenga | 2 - 1 | Sarpsborg 08 |
| 21 Apr 21 |
r03 | | Rosenborg | 2 - 1 | Ranheim |
| 21 Apr 21 |
r03 | | Hartford Ath | 3 - 3 | Bethlehem St |
| 21 Apr 21 |
r03 | | Sandnes | 1 - 1 | Viking |
| 23 Apr 21 |
r03 | | Kristiansund | 0 - 0 | Molde |
| 23 Apr 21 |
r03 | | Raufoss | 4 - 1 | Hamarkamerat |
| 23 Apr 21 |
r03 | | North Caroli | 0 - 1 | Charlotte In |
| 23 Apr 21 |
r03 | | KTP | - | HIFK Fotboll |
| 24 Apr 21 |
r03 | | Hartford Ath | - | FC Motown |
| 24 Apr 21 |
r03 | | Las Vegas Li | - | Oakland Root |
| 24 Apr 21 |
r03 | | KV Oostende | 0 - 3 | Anderlecht |
| 24 Apr 21 |
r03 | | KTP | 0 - 1 | JIPPO |
| 24 Apr 21 |
r03 | | Ilves | 2 - 0 | Mariehamn |
| 24 Apr 21 |
r03 | | JJK | 1 - 1 | MP |
| 24 Apr 21 |
r03 | | FC Haka | 1 - 1 | Klubi-04 |
| 24 Apr 21 |
r03 | | FC Lahti | 4 - 2 | Gnistan |
| 24 Apr 21 |
r03 | | Strommen | 2 - 2 | Grorud IL |
| 24 Apr 21 |
r03 | | SJK Seinajok | 1 - 1 | AC Oulu |
| 24 Apr 21 |
r03 | | RoPS | 0 - 0 | Jaro |
| 24 Apr 21 |
r03 | | Swope Park R | 0 - 1 | Forward Madi |
| 24 Apr 21 |
r03 | | San Antonio | 2 - 2 | Rio Grande V |
| 24 Apr 21 |
r03 | | Indy Eleven | 1 - 1 | Pittsburgh R |
| 24 Apr 21 |
r03 | | Memphis 901 | 1 - 2 | Chattanooga |
| 24 Apr 21 |
r03 | | Sacramento R | 2 - 0 | Real Monarch |
| 24 Apr 21 |
r03 | | Phoenix Risi | 0 - 4 | New Mexico U |
| 25 Apr 21 |
r03 | | Rosenborg | 1 - 0 | Tromso |
| 25 Apr 21 |
r03 | | Orange Count | 2 - 2 | Colorado Spr |
| 25 Apr 21 |
r03 | | Phoenix Risi | 2 - 1 | FC Tucson |
| 25 Apr 21 |
r03 | | Bodoe/Glimt | 4 - 1 | Brann |
| 25 Apr 21 |
r03 | | Mjoendalen | 1 - 4 | Fredrikstad |
| 25 Apr 21 |
r03 | | Odd Ballklub | 1 - 0 | Stabaek |
| 25 Apr 21 |
r03 | | Viking | 3 - 3 | Start |
| 25 Apr 21 |
r03 | | FK Haugesund | 1 - 1 | ASANE FOTBAL |
| 25 Apr 21 |
r03 | | Bethlehem St | 4 - 2 | Loudoun Unit |
| 26 Apr 21 |
r03 | | Stroemsgodse | 1 - 0 | Sandefjord |
| 28 Apr 21 |
r03 | | Hamarkamerat | 4 - 0 | Ull Kisa |
| 28 Apr 21 |
r03 | | Rosenborg | 3 - 0 | Kristiansund |
| 28 Apr 21 |
r03 | | Molde | 2 - 0 | Sogndal |
| 28 Apr 21 |
r03 | | Hamarkamerat | - | Kongsvinger |
| 28 Apr 21 |
r03 | | Vaalerenga | 6 - 1 | Raufoss |
| 28 Apr 21 |
r03 | | Brann | 3 - 3 | Sandnes |
| 28 Apr 21 |
r03 | | Fredrikstad | 2 - 1 | Strommen |
| 29 Apr 21 |
r03 | | Las Vegas Li | - | San Diego 19 |
| 29 Apr 21 |
r03 | | MP | 1 - 0 | PK-35 |
| 30 Apr 21 |
r03 | | North Caroli | 2 - 1 | Charleston B |
| 01 May 21 |
r03 | | Bryne | 1 - 0 | JERV |
| 01 May 21 |
r03 | | Pittsburgh R | 4 - 2 | Bethlehem St |
| 02 May 21 |
r03 | | Ranheim | 2 - 1 | Rosenborg |
| 02 May 21 |
r03 | | Stroemsgodse | 1 - 6 | Fredrikstad |
| 02 May 21 |
r03 | | Sogndal | 3 - 4 | Raufoss |
| 02 May 21 |
r03 | | Mjoendalen | 2 - 1 | Lillestroem |
| 02 May 21 |
r03 | | Stabaek | 2 - 1 | Hamarkamerat |
| 02 May 21 |
r03 | | Start | 1 - 1 | Sandefjord |
| 02 May 21 |
r03 | | Sarpsborg 08 | 1 - 0 | Odd Ballklub |
| 02 May 21 |
r03 | | Molde | 1 - 1 | Bodoe/Glimt |
| 02 May 21 |
r03 | | ASANE FOTBAL | 1 - 2 | Brann |
| 02 May 21 |
r03 | | Vaalerenga | 3 - 4 | Tromso |
| 02 May 21 |
r03 | | Kristiansund | 0 - 4 | Aalesund |
| 02 May 21 |
r03 | | Viking | 4 - 0 | FK Haugesund |
| 05 May 21 |
r03 | | Hamarkamerat | 1 - 5 | Raufoss |
| 08 May 21 |
r03 | | Sogndal | 0 - 1 | Hamarkamerat |
| 08 May 21 |
r03 | | Fredrikstad | 4 - 2 | Grorud IL |
| 08 May 21 |
r03 | | Strommen | 1 - 2 | KFUM |
| 08 May 21 |
r03 | | Sandnes | 1 - 0 | Bryne |
| 08 May 21 |
r03 | | Raufoss | 2 - 1 | Ull Kisa |
| 08 May 21 |
r03 | | Ranheim | 1 - 2 | Stjørdals-B |
| 08 May 21 |
r03 | | Mjoendalen | 1 - 1 | Sarpsborg 08 |
| 09 May 21 |
r03 | | Memphis 901 | 5 - 0 | Little Rock |
| 09 May 21 |
r03 | | Start | 1 - 1 | FK Haugesund |
| 09 May 21 |
r03 | | Stabaek | 0 - 1 | Lillestroem |
| 22 May 21 |
r04 | | Basford Utd. | 3 - 0 | Mickleover S |
| 26 May 21 |
r03 | | Charleroi | 3 - 1 | Fola |
| 28 May 21 |
r04 | | Worksop Town | 5 - 0 | Mickleover S |
| 30 May 21 |
r03 | | Øygarden FK | 2 - 3 | Hoedd |
| 30 May 21 |
r03 | | Tromsdalen | 2 - 1 | Alta |
| 01 Jun 21 |
r03 | | Raufoss | 4 - 4 | Ull Kisa |
| 02 Jun 21 |
r03 | | Skeid | 2 - 4 | Stabaek |
| 03 Jun 21 |
r03 | | Lillestroem | 5 - 0 | Hamarkamerat |
| 04 Jun 21 |
r03 | | Stjørdals-B | 3 - 1 | Levanger |
| 04 Jun 21 |
r03 | | Mjoendalen | 3 - 1 | Ull Kisa |
| 05 Jun 21 |
r03 | | Phönix Lüb | 4 - 1 | Teutonia Ott |
| 05 Jun 21 |
r03 | | Kongsvinger | 1 - 1 | Skeid |
| 05 Jun 21 |
r04 | | Cumbernauld | 2 - 2 | Musselburgh |
| 07 Jun 21 |
r03 | | Brann | 3 - 0 | Øygarden FK |
| 08 Jun 21 |
r03 | | Raufoss | 2 - 1 | Kongsvinger |
| 12 Jun 21 |
r03 | | Tromsdalen | 2 - 1 | Alta |
| 12 Jun 21 |
r04 | | The Spartans | 2 - 2 | Lothian This |
| 12 Jun 21 |
r03 | | Malmo FF | 0 - 1 | Kalmar FF |
| 12 Jun 21 |
r03 | | Øygarden FK | 5 - 0 | Floroe |
| 12 Jun 21 |
r03 | | Chayka Pesch | 2 - 0 | Akron Tolyat |
| 12 Jun 21 |
r03 | | FC Ufa | 0 - 2 | Veles Moscow |
| 13 Jun 21 |
r03 | | Eintracht No | 3 - 3 | Heider SV |
| 13 Jun 21 |
r03 | | Hoedd | 2 - 0 | Aalesund |
| 13 Jun 21 |
r03 | | Baerum | 0 - 3 | Notodden |
| 14 Jun 21 |
r04 | | Birkirkara | 3 - 1 | Hibernians F |
| 14 Jun 21 |
r03 | | Spartak-2 Mo | 0 - 4 | Baltika Kali |
| 16 Jun 21 |
r03 | | FC Ufa | 2 - 1 | Chayka Pesch |
| 16 Jun 21 |
r03 | | Ludogorets R | 2 - 0 | SV Heimstett |
| 17 Jun 21 |
r03 | | SV Lafnitz | 1 - 2 | Videoton FC |
| 18 Jun 21 |
r03 | | Sheriff Tira | 1 - 0 | Akron Tolyat |
| 18 Jun 21 |
r03 | | Radomlje | 1 - 1 | Domzale |
| 18 Jun 21 |
r03 | | Ħamrun Spar | 2 - 1 | SK Vorwarts |
| 19 Jun 21 |
r03 | | Lask Juniors | 0 - 5 | Puskás Akad |
| 19 Jun 21 |
r04 | | Portstewart | 0 - 2 | Coleraine |
| 19 Jun 21 |
r03 | | Dukla Praha | 2 - 0 | Sparta Pragu |
| 19 Jun 21 |
r03 | | Baltika Kali | 0 - 2 | FC Ufa |
| 19 Jun 21 |
r03 | | Gaz Metan Me | 1 - 2 | 1599 Șelimb |
| 19 Jun 21 |
r03 | | Hacken | 1 - 0 | Oerebro |
| 19 Jun 21 |
r03 | | Eintracht No | - | Hannoversche |
| 19 Jun 21 |
r03 | | Mjallby | 1 - 2 | Halmstad |
| 19 Jun 21 |
r03 | | Djurgaarden | 2 - 3 | Kalmar FF |
| 19 Jun 21 |
r03 | | Malmo FF | 2 - 0 | Elfsborg |
| 19 Jun 21 |
r03 | | Veles Moscow | 0 - 2 | Volgar Astra |
| 19 Jun 21 |
r03 | | CFR Cluj-Nap | 1 - 1 | Ludogorets R |
| 19 Jun 21 |
r03 | | Spartak-2 Mo | 1 - 2 | SKA-Khabarov |
| 19 Jun 21 |
r03 | | CSKA Sofia | 2 - 0 | Litex Lovech |
| 19 Jun 21 |
r03 | | Tatran Lipto | 2 - 1 | MFK Zemplín |
| 19 Jun 21 |
r03 | | Slavia Sofia | 3 - 0 | Marek Dupnit |
| 19 Jun 21 |
r03 | | FC Trenkwald | 4 - 0 | SV Horn |
| 19 Jun 21 |
r03 | | TSC Bačka T | 2 - 3 | Spartak Subo |
| 19 Jun 21 |
r03 | | NŠ Mura | 0 - 4 | Dinamo Zagre |
| 20 Jun 21 |
r03 | | Gazovik Oren | 2 - 0 | Videoton FC |
| 20 Jun 21 |
r03 | | AIK | 3 - 3 | Sirius |
| 20 Jun 21 |
r03 | | Legia Warsaw | 0 - 2 | Ferencvaros |
| 20 Jun 21 |
r03 | | SV Kapfenber | 1 - 4 | Slovan Brati |
| 21 Jun 21 |
r03 | | Fakel Vorone | 3 - 1 | Torpedo Mosc |
| 21 Jun 21 |
r03 | | PFC Sochi | 2 - 3 | FC Krasnodar |
| 21 Jun 21 |
r03 | | Olimpija Lju | 1 - 1 | Neftçi PFK |
| 22 Jun 21 |
r04 | | Gżira Unite | 3 - 0 | Hibernians F |
| 22 Jun 21 |
r03 | | Hammarby | 1 - 0 | Österlen FF |
| 22 Jun 21 |
r03 | | Mladost Luč | 0 - 0 | Kolubara |
| 22 Jun 21 |
r03 | | NK Maribor | - | Slovan Brati |
| 22 Jun 21 |
r03 | | Lokomotiv Pl | 3 - 1 | Septemvri Si |
| 22 Jun 21 |
r03 | | Spartak Subo | 0 - 5 | Krylya Sovet |
| 22 Jun 21 |
r03 | | MFK Ružombe | 3 - 0 | Kosice |
| 22 Jun 21 |
r03 | | Akron Tolyat | 1 - 0 | Sfântul Ghe |
| 22 Jun 21 |
r03 | | CFR Cluj-Nap | 0 - 1 | Puskás Akad |
| 22 Jun 21 |
r03 | | Slovacko | 6 - 1 | Vyškov |
| 22 Jun 21 |
r03 | | Harelbeke | 0 - 5 | Kortrijk |
| 22 Jun 21 |
r03 | | East Kilbrid | 2 - 1 | Dumbarton |
| 23 Jun 21 |
r03 | | Academica Cl | 1 - 0 | Chindia Târ |
| 23 Jun 21 |
r03 | | Keçiöreng� | 1 - 4 | Dinamo Bucur |
| 23 Jun 21 |
r03 | | Young Boys | - | SC Kriens |
| 23 Jun 21 |
r03 | | Radomlje | 2 - 2 | NK Bravo |
| 23 Jun 21 |
r04 | | Metalac GM | 1 - 0 | Dečić |
| 23 Jun 21 |
r03 | | Dorados | 1 - 4 | Tijuana |
| 23 Jun 21 |
r03 | | Farul Consta | 2 - 0 | FC Braşov |
| 23 Jun 21 |
r03 | | Volgar Astra | 2 - 1 | Olimp-Dolgop |
| 23 Jun 21 |
r03 | | Varbergs BoI | 1 - 0 | Elfsborg |
| 23 Jun 21 |
r03 | | Rakow Czesto | 2 - 4 | Lechia Gdań |
| 23 Jun 21 |
r03 | | IFK Gothenbu | 1 - 2 | Brøndby |
| 23 Jun 21 |
r03 | | Zorya | 3 - 3 | FC Olexandri |
| 23 Jun 21 |
r03 | | Legia Warsaw | 1 - 1 | FC Krasnodar |
| 23 Jun 21 |
r03 | | Chayka Pesch | 5 - 1 | StavAgrosoyu |
| 23 Jun 21 |
r03 | | Ludogorets R | 1 - 3 | Ferencvaros |
| 23 Jun 21 |
r03 | | CSKA 1948 | 2 - 3 | Slavia Sofia |
| 23 Jun 21 |
r03 | | Tsarsko Selo | 4 - 0 | Strumska Sla |
| 23 Jun 21 |
r03 | | Lok. Moscow | 3 - 2 | MSK Zilina |
| 23 Jun 21 |
r03 | | Radnički 19 | 1 - 0 | Novi Pazar |
| 23 Jun 21 |
r03 | | Wiener Neust | 1 - 3 | CSKA Moscow |
| 23 Jun 21 |
r03 | | Vojvodina | 1 - 0 | Slask Wrocla |
| 23 Jun 21 |
r03 | | Tatran Lipto | 1 - 0 | FK Pohronie |
| 23 Jun 21 |
r03 | | Rijeka | 1 - 0 | Domzale |
| 23 Jun 21 |
r03 | | East Fife | 1 - 1 | TNS |
| 23 Jun 21 |
r03 | | Clachnacuddi | 0 - 5 | Inverness C |
| 24 Jun 21 |
r04 | | Struga | 1 - 1 | Partizani |
| 24 Jun 21 |
r04 | | Sileks | 0 - 1 | KS Teuta |
| 24 Jun 21 |
r03 | | Proleter Nov | 1 - 3 | Krylya Sovet |
| 24 Jun 21 |
r03 | | Dinamo Zagre | 3 - 0 | ŠKF Sereď |
| 24 Jun 21 |
r03 | | Dinamo Zagre | - | Slovan Brati |
| 24 Jun 21 |
r03 | | Berliner AK | 2 - 2 | Hertha Zehle |
| 24 Jun 21 |
r03 | | FK Rubin Kaz | 2 - 1 | Nizhny Novgo |
| 24 Jun 21 |
r03 | | HOBRO | 1 - 0 | AaB |
| 24 Jun 21 |
r03 | | Norrkoping | 1 - 0 | Oerebro |
| 24 Jun 21 |
r03 | | FC Copenhage | 1 - 1 | Hvidovre IF |
| 24 Jun 21 |
r03 | | Gazovik Oren | 0 - 1 | Slovan Brati |
| 24 Jun 21 |
r03 | | FK Rostov | 2 - 2 | Videoton FC |
| 25 Jun 21 |
r03 | | Paderborn | - | Duisburg |
| 25 Jun 21 |
r03 | | Baltika Kali | - | Neftekhimik |
| 25 Jun 21 |
r03 | | Uta Arad | 2 - 0 | 1599 Șelimb |
| 25 Jun 21 |
r03 | | Pirin Blagoe | 6 - 1 | Marek Dupnit |
| 25 Jun 21 |
r03 | | Arda Kardzha | 2 - 1 | Maritsa Plov |
| 25 Jun 21 |
r03 | | Berliner FC | 1 - 2 | Viktoria Ber |
| 25 Jun 21 |
r03 | | Pumas | - | FC Juarez |
| 25 Jun 21 |
r03 | | Chrudim | 1 - 0 | Vysočina Ji |
| 25 Jun 21 |
r03 | | Inhulets | 2 - 0 | FC Kolos Kov |
| 25 Jun 21 |
r03 | | Akron Tolyat | 3 - 0 | Florești |
| 25 Jun 21 |
r03 | | FC U Craiova | 0 - 2 | FC Ufa |
| 25 Jun 21 |
r03 | | Montana | 2 - 0 | Sportist Svo |
| 25 Jun 21 |
r03 | | Berwick Rang | - | Hearts |
| 25 Jun 21 |
r04 | | Shkendija 79 | 2 - 1 | Laci |
| 25 Jun 21 |
r03 | | Lyngby | - | Hvidovre IF |
| 25 Jun 21 |
r03 | | Hamburg | - | VSG Altglien |
| 25 Jun 21 |
r03 | | FC Lausanne- | 4 - 2 | Neuchâtel X |
| 25 Jun 21 |
r03 | | Zaglebie Lub | 0 - 3 | Pogon Szczec |
| 25 Jun 21 |
r03 | | Anderlecht | 1 - 1 | St.Truiden |
| 25 Jun 21 |
r03 | | Zurich | 2 - 2 | FC Wil |
| 25 Jun 21 |
r03 | | FC Liefering | 1 - 2 | SV Josko Rie |
| 25 Jun 21 |
r03 | | Grasshoppers | 2 - 4 | Schaffhausen |
| 25 Jun 21 |
r03 | | Baltika Kali | 3 - 1 | Rotor Volgog |
| 25 Jun 21 |
r03 | | NK Aluminij | 0 - 1 | Puskás Akad |
| 25 Jun 21 |
r03 | | Sturm Graz | 6 - 0 | Lask Juniors |
| 25 Jun 21 |
r03 | | Neftekhimik | 1 - 1 | Tekstilshchi |
| 25 Jun 21 |
r03 | | Beroe | 1 - 1 | Yantra Gabro |
| 25 Jun 21 |
r03 | | Sochaux | 3 - 0 | F91 Dudelang |
| 25 Jun 21 |
r03 | | Germania Hal | 1 - 3 | Braunschweig |
| 25 Jun 21 |
r03 | | SV Salzburg | 3 - 1 | DAC 1904 Dun |
| 26 Jun 21 |
r03 | | Wuerzburger | 1 - 2 | Sandhausen |
| 26 Jun 21 |
r03 | | Glentoran | 1 - 0 | Coleraine |
| 26 Jun 21 |
r03 | | Kelty Hearts | 2 - 3 | Partick |
| 26 Jun 21 |
r03 | | Raith Rvs | 4 - 1 | Stranraer |
| 26 Jun 21 |
r03 | | Khimki FK | 0 - 1 | Olimp-Dolgop |
| 26 Jun 21 |
r03 | | Alianza Lima | 0 - 0 | Academia Dep |
| 26 Jun 21 |
r03 | | Vorskla | 3 - 0 | SC Dnipro-1 |
| 26 Jun 21 |
r03 | | Mynai | 0 - 2 | FC Lviv |
| 26 Jun 21 |
r03 | | Tekstilshchi | 2 - 0 | FC Ryazan |
| 26 Jun 21 |
r03 | | Universitate | 1 - 2 | Hajduk Split |
| 26 Jun 21 |
r03 | | Leon | 1 - 3 | Morelia |
| 26 Jun 21 |
r03 | | Wacker Innsb | 0 - 1 | CSKA Sofia |
| 26 Jun 21 |
r03 | | NŠ Mura | 2 - 2 | Partizan Bel |
| 26 Jun 21 |
r03 | | Apollon Lima | 3 - 4 | Omonia Nicos |
| 26 Jun 21 |
r03 | | NK Bravo | 1 - 3 | MSK Zilina |
| 26 Jun 21 |
r03 | | Šibenik | 2 - 1 | Zrinjski |
| 26 Jun 21 |
r03 | | Dečić | 1 - 1 | Spartak Subo |
| 26 Jun 21 |
r03 | | Buducnost Po | 3 - 2 | Krylya Sovet |
| 26 Jun 21 |
r03 | | Buducnost Po | 2 - 1 | Radnički 19 |
| 26 Jun 21 |
r03 | | CD Guadalaja | - | Necaxa |
| 26 Jun 21 |
r03 | | Kispest Honv | 1 - 0 | Ajka |
| 26 Jun 21 |
r03 | | MTK Hungaria | 7 - 2 | III Kerület |
| 26 Jun 21 |
r03 | | Farul Consta | 1 - 1 | Rapid Bucure |
| 26 Jun 21 |
r03 | | Sparta Pragu | - | Dukla Praha |
| 26 Jun 21 |
r03 | | Kolubara | 0 - 1 | Metalac GM |
| 26 Jun 21 |
r03 | | Kazincbarcik | 1 - 3 | Kisvárda FC |
| 26 Jun 21 |
r03 | | Civil Servic | 2 - 2 | Dunfermline |
| 26 Jun 21 |
r03 | | Clachnacuddi | - | Broxburn Ath |
| 26 Jun 21 |
r03 | | Tatran Lipto | - | ŠKF Sereď |
| 26 Jun 21 |
r03 | | CSA Steaua B | 1 - 2 | Academica Cl |
| 26 Jun 21 |
r04 | | Gżira Unite | 3 - 0 | Birkirkara |
| 26 Jun 21 |
r03 | | MFK Ružombe | - | Wisla Krakow |
| 26 Jun 21 |
r03 | | MFK Zemplín | - | Kosice |
| 26 Jun 21 |
r03 | | Cimarrones d | - | Tijuana |
| 26 Jun 21 |
r03 | | Fakel Vorone | 1 - 1 | Veles Moscow |
| 26 Jun 21 |
r03 | | Levski Sofia | 1 - 0 | Lokomotiv Pl |
| 26 Jun 21 |
r03 | | Tsarsko Selo | 4 - 1 | Minyor Perni |
| 26 Jun 21 |
r03 | | Cherno More | 1 - 0 | CSKA 1948 |
| 26 Jun 21 |
r03 | | Viktoria Plz | 4 - 1 | FC Spartak T |
| 26 Jun 21 |
r03 | | Slovacko | 5 - 0 | Prostějov |
| 26 Jun 21 |
r03 | | Pardubice | 0 - 2 | Zbrojovka Br |
| 26 Jun 21 |
r03 | | Sigma Olomou | 3 - 0 | Vyškov |
| 26 Jun 21 |
r03 | | Wisla Plock | - | Rakow Czesto |
| 26 Jun 21 |
r03 | | Hradec Král | 3 - 1 | Bohemians 19 |
| 26 Jun 21 |
r03 | | Liberec | 5 - 0 | Viktoria Ži |
| 26 Jun 21 |
r03 | | Osijek | 1 - 2 | Slask Wrocla |
| 26 Jun 21 |
r03 | | Wisla Krakow | 3 - 2 | Stal Mielec |
| 26 Jun 21 |
r03 | | Karvina | 0 - 3 | Trencin |
| 26 Jun 21 |
r03 | | Cracovia Kra | 2 - 0 | Třinec |
| 26 Jun 21 |
r03 | | AC Horsens | 1 - 1 | Randers FC |
| 26 Jun 21 |
r03 | | FC Winterthu | 2 - 5 | Vaduz |
| 26 Jun 21 |
r03 | | Optik Rathen | 2 - 2 | Tennis Borus |
| 26 Jun 21 |
r03 | | Paderborn | 5 - 1 | SC Verl |
| 26 Jun 21 |
r03 | | Dumbarton | 1 - 0 | Motherwell |
| 26 Jun 21 |
r03 | | AGF Aarhus | 0 - 1 | FC Nordsjæl |
| 26 Jun 21 |
r03 | | AaB | 2 - 2 | Viborg |
| 26 Jun 21 |
r03 | | Dynamo Dresd | 3 - 1 | Hertha II |
| 26 Jun 21 |
r03 | | Jong Utrecht | 1 - 1 | Jong AZ |
| 26 Jun 21 |
r03 | | Forfar | 0 - 3 | Dundee FC |
| 26 Jun 21 |
r03 | | Hannover | 0 - 2 | St Pauli |
| 26 Jun 21 |
r03 | | Montrose | 1 - 1 | Arbroath |
| 26 Jun 21 |
r03 | | Eintracht No | - | Teutonia Ott |
| 26 Jun 21 |
r03 | | FC Krasnodar | 0 - 1 | FC Forte Tag |
| 26 Jun 21 |
r03 | | FC Heidenhei | 5 - 4 | Austria Lust |
| 26 Jun 21 |
r03 | | Nurnberg | 5 - 1 | Zwickau |
| 26 Jun 21 |
r03 | | SKN St. Polt | 0 - 2 | NK Aluminij |
| 26 Jun 21 |
r03 | | Waregem | 0 - 4 | St. Gilloise |
| 26 Jun 21 |
r03 | | FC Trenkwald | 0 - 4 | Slovan Brati |
| 26 Jun 21 |
r03 | | SV Lafnitz | 2 - 5 | Rapid Vienna |
| 26 Jun 21 |
r03 | | Austria Vien | 2 - 1 | SK Vorwarts |
| 26 Jun 21 |
r03 | | Gazovik Oren | 4 - 1 | FK Senica |
| 26 Jun 21 |
r03 | | Wolfsberger | 1 - 0 | Olympiakos |
| 26 Jun 21 |
r03 | | Petrocub Hî | 1 - 0 | Akron Tolyat |
| 26 Jun 21 |
r03 | | Jahn Regensb | 4 - 0 | FC BW Linz |
| 26 Jun 21 |
r03 | | Lok. Moscow | 6 - 1 | Olimpija Lju |
| 26 Jun 21 |
r03 | | USL Dunkerqu | 1 - 1 | Cercle Brugg |
| 26 Jun 21 |
r03 | | Club Brugge | 1 - 1 | Beerschot VA |
| 26 Jun 21 |
r03 | | Celje | 0 - 1 | HNK Gorica |
| 26 Jun 21 |
r03 | | Slaven Belup | 1 - 1 | Slask Wrocla |
| 26 Jun 21 |
r03 | | CFR Cluj-Nap | 1 - 0 | Dinamo Mosco |
| 26 Jun 21 |
r03 | | Mladost Luč | 1 - 2 | Voždovac |
| 26 Jun 21 |
r03 | | Rijeka | 3 - 0 | Hrvatski Dra |
| 26 Jun 21 |
r03 | | NK Maribor | 4 - 1 | Vojvodina |
| 27 Jun 21 |
r03 | | Ural S.R | - | FK Rubin Kaz |
| 27 Jun 21 |
r03 | | Cancún | 1 - 1 | Monterrey |
| 27 Jun 21 |
r03 | | VfV Hildeshe | - | Chemie Leipz |
| 27 Jun 21 |
r03 | | Volgar Astra | 1 - 2 | FC Yenisey K |
| 27 Jun 21 |
r03 | | Spartak-2 Mo | 7 - 0 | Chertanovo M |
| 27 Jun 21 |
r03 | | Zorya | 1 - 2 | Proleter Nov |
| 27 Jun 21 |
r03 | | Eintracht No | - | St Pauli |
| 27 Jun 21 |
r03 | | Malmo FF | 1 - 2 | FC Midtjylla |
| 27 Jun 21 |
r03 | | FC Basel | 2 - 3 | Thun |
| 27 Jun 21 |
r03 | | Ludogorets R | 3 - 0 | LASK |
| 27 Jun 21 |
r03 | | Hammarby | 3 - 1 | Sirius |
| 27 Jun 21 |
r03 | | Botev Plovdi | 1 - 1 | Zorya |
| 27 Jun 21 |
r03 | | Malmo FF | 2 - 0 | Køge |
| 27 Jun 21 |
r01 | | Galatasaray | 2 - 1 | Dinamo Bucur |
| 27 Jun 21 |
r03 | | Dinamo Zagre | 2 - 1 | FK Rostov |
| 27 Jun 21 |
r03 | | FC Krasnodar | 0 - 1 | Olympiakos |
| 27 Jun 21 |
r03 | | SV Kapfenber | 0 - 1 | CSKA Moscow |
| 27 Jun 21 |
r04 | | Marienlyst | - | B 1909 |
| 27 Jun 21 |
r03 | | Radomlje | 0 - 1 | Cukaricki |
| 27 Jun 21 |
r03 | | Novi Pazar | 2 - 2 | KF Vllaznia |
| 27 Jun 21 |
r03 | | Tabor Sežan | 0 - 2 | TSC Bačka T |
| 28 Jun 21 |
r03 | | Fredericia | 0 - 4 | Mjallby |
| 28 Jun 21 |
r03 | | Degerfors | 2 - 2 | Djurgaarden |
| 28 Jun 21 |
r03 | | Alania Vladi | - | Chayka Pesch |
| 28 Jun 21 |
r04 | | Mosta FC | 0 - 1 | Hibernians F |
| 28 Jun 21 |
r03 | | AIK | 0 - 1 | Ostersund |
| 28 Jun 21 |
r03 | | Sirius | 0 - 2 | Hammarby |
| 28 Jun 21 |
r03 | | Brøndby | 4 - 1 | Sønderjyske |
| 28 Jun 21 |
r03 | | Hacken | 0 - 2 | Halmstad |
| 28 Jun 21 |
r03 | | Young Boys | 4 - 1 | Neuchâtel X |
| 28 Jun 21 |
r03 | | Baltika Kali | 2 - 0 | Torpedo Mosc |
| 28 Jun 21 |
r03 | | Cherno More | 0 - 0 | Strumska Sla |
| 28 Jun 21 |
r03 | | CFR Cluj-Nap | 1 - 1 | Újpest FC |
| 28 Jun 21 |
r03 | | Crvena Zvezd | 4 - 0 | Grazer AK |
| 29 Jun 21 |
r03 | | Saturn Ramen | 0 - 3 | Tekstilshchi |
| 29 Jun 21 |
r03 | | Larne | 1 - 2 | Coleraine |
| 29 Jun 21 |
r03 | | Vejle Boldkl | 0 - 5 | Silkeborg IF |
| 29 Jun 21 |
r03 | | Wolfsberger | 0 - 0 | FC Ufa |
| 29 Jun 21 |
r03 | | Volyn | 0 - 0 | Veres Rivne |
| 29 Jun 21 |
r03 | | Helsingborg | 2 - 0 | Varbergs BoI |
| 29 Jun 21 |
r03 | | Rotor Volgog | 2 - 0 | Tomsk |
| 29 Jun 21 |
r03 | | CSKA 1948 | 2 - 3 | Shkendija 79 |
| 29 Jun 21 |
r03 | | WSG Swarovsk | 1 - 3 | FC U Craiova |
| 29 Jun 21 |
r03 | | NK Bravo | 1 - 1 | Universitate |
| 29 Jun 21 |
r03 | | Raith Rvs | 0 - 1 | Clyde |
| 29 Jun 21 |
r03 | | Tekstilshchi | 0 - 2 | Veles Moscow |
| 29 Jun 21 |
r03 | | Liberec | 1 - 3 | Dukla Praha |
| 29 Jun 21 |
r03 | | FC Copenhage | 3 - 1 | Lyngby |
| 29 Jun 21 |
r03 | | Ahrobiznes | 1 - 1 | FC Lviv |
| 29 Jun 21 |
r03 | | Slovacko | 3 - 0 | Tatran Lipto |
| 29 Jun 21 |
r03 | | Neftekhimik | 2 - 0 | Shinnik Yaro |
| 29 Jun 21 |
r03 | | Spartak Mosc | 1 - 2 | Neftçi PFK |
| 29 Jun 21 |
r03 | | Gazovik Oren | 1 - 2 | Gyirmót |
| 29 Jun 21 |
r03 | | Pogon Szczec | 0 - 1 | MFK Ružombe |
| 29 Jun 21 |
r03 | | Hajduk Split | 4 - 0 | Slask Wrocla |
| 29 Jun 21 |
r03 | | Næsby | 1 - 3 | Odense BK |
| 29 Jun 21 |
r03 | | Sochaux | - | CA Pontarlie |
| 29 Jun 21 |
r03 | | SV Salzburg | 3 - 0 | Olympiakos |
| 29 Jun 21 |
r03 | | Olimpija Lju | - | Borac Banja |
| 29 Jun 21 |
r03 | | Dumbarton | 0 - 0 | Morton |
| 29 Jun 21 |
r03 | | Montrose | - | Fraserburgh |
| 30 Jun 21 |
r03 | | Voždovac | 0 - 1 | Metalac GM |
| 30 Jun 21 |
r03 | | Mechelen | 2 - 7 | FC Utrecht |
| 30 Jun 21 |
r03 | | Vitesse | 1 - 3 | AEK |
| 30 Jun 21 |
r03 | | PFC Sochi | 1 - 2 | PFC Kuban Kr |
| 30 Jun 21 |
r03 | | Rabotnichki | 0 - 0 | Napredak Kru |
| 30 Jun 21 |
r03 | | Farul Consta | 1 - 2 | Chindia Târ |
| 30 Jun 21 |
r03 | | Pachuca | - | Pumas |
| 30 Jun 21 |
r03 | | Hamburg | 1 - 0 | Wacker Innsb |
| 30 Jun 21 |
r03 | | Ferencvaros | 1 - 0 | DAC 1904 Dun |
| 30 Jun 21 |
r03 | | SKN St. Polt | 1 - 1 | Újpest FC |
| 30 Jun 21 |
r03 | | Tennis Borus | 1 - 8 | Magdeburg |
| 30 Jun 21 |
r03 | | SV Heimstett | 2 - 8 | Munich 1860 |
| 30 Jun 21 |
r03 | | Békéscsaba | 1 - 2 | Kisvárda FC |
| 30 Jun 21 |
r03 | | Sozopol | 1 - 6 | Pirin Blagoe |
| 30 Jun 21 |
r03 | | Eichstätt | 0 - 4 | Ingolstadt |
| 30 Jun 21 |
r03 | | Fola | 2 - 1 | FC Saarbrüc |
| 30 Jun 21 |
r03 | | Partizan Bel | 3 - 0 | Koper |
| 30 Jun 21 |
r03 | | Krylya Sovet | 3 - 0 | Radnički Ni |
| 30 Jun 21 |
r04 | | CSKA 1948 II | 0 - 2 | Maritsa Plov |
| 30 Jun 21 |
r04 | | Gżira Unite | 2 - 1 | Ħamrun Spar |
| 30 Jun 21 |
r04 | | Rudar Pljevl | 0 - 2 | Sloboda |
| 30 Jun 21 |
r03 | | Jagiellonia | - | Znicz Pruszk |
| 30 Jun 21 |
r03 | | CD Guadalaja | - | Tapatío |
| 30 Jun 21 |
r03 | | Gornik Zabrz | - | Podbeskidzie |
| 30 Jun 21 |
r03 | | FC Yenisey K | - | Olimp-Dolgop |
| 30 Jun 21 |
r03 | | Necaxa | 8 - 1 | Mineros de Z |
| 30 Jun 21 |
r03 | | Monterrey | 4 - 0 | Venados |
| 30 Jun 21 |
r03 | | Volgar Astra | 1 - 2 | Fakel Vorone |
| 30 Jun 21 |
r03 | | Kispest Honv | 4 - 1 | Budaörs |
| 30 Jun 21 |
r03 | | Farul Consta | 1 - 0 | CS Mioveni |
| 30 Jun 21 |
r03 | | Viktoria Ži | 2 - 0 | Táborsko |
| 30 Jun 21 |
r03 | | Karvina | 1 - 2 | Gornik Zabrz |
| 30 Jun 21 |
r03 | | Steaua Bucur | 5 - 1 | ACS Sirineas |
| 30 Jun 21 |
r03 | | Linfield | 0 - 1 | Kilmarnock |
| 30 Jun 21 |
r03 | | Beerschot VA | 2 - 1 | SC Verl |
| 30 Jun 21 |
r03 | | Braunschweig | 3 - 3 | Hertha II |
| 30 Jun 21 |
r03 | | PEC Zwolle | 1 - 1 | Dortmund II |
| 30 Jun 21 |
r03 | | Sparta Pragu | 4 - 1 | Nurnberg II |
| 30 Jun 21 |
r03 | | Khimki FK | 0 - 1 | Fakel Vorone |
| 30 Jun 21 |
r03 | | Eupen | 2 - 1 | RFC Seraing |
| 30 Jun 21 |
r03 | | Inhulets | 2 - 0 | Kryvbas Kryv |
| 30 Jun 21 |
r03 | | SKA-Khabarov | 2 - 1 | Tomsk |
| 30 Jun 21 |
r03 | | Bohemians 19 | 3 - 5 | Vlašim |
| 30 Jun 21 |
r03 | | Teplice | - | Varnsdorf |
| 30 Jun 21 |
r03 | | Liberec | 3 - 1 | Ústí nad L |
| 30 Jun 21 |
r03 | | Stal Mielec | 4 - 1 | Puszcza Niep |
| 30 Jun 21 |
r03 | | Dynamo Dresd | 3 - 1 | Jablonec |
| 30 Jun 21 |
r03 | | AaB | 0 - 0 | Esbjerg |
| 30 Jun 21 |
r03 | | Legia Warsaw | 3 - 2 | Lechia Gdań |
| 30 Jun 21 |
r03  |  | Viktoria Plz | 3 - 0 | Pribram |
| 30 Jun 21 |
r03 | | FC Heidenhei | 2 - 0 | SC Rheindorf |
| 30 Jun 21 |
r03 | | Cherno More | 3 - 2 | Arda Kardzha |
| 30 Jun 21 |
r03 | | St.Truiden | 2 - 1 | Lierse Kempe |
| 30 Jun 21 |
r03 | | Optik Rathen | 1 - 1 | SV Babelsber |
| 30 Jun 21 |
r03 | | Hansa Rostoc | 9 - 1 | Berliner AK |
| 30 Jun 21 |
r03 | | Botev Plovdi | 1 - 1 | Proleter Nov |
| 30 Jun 21 |
r03 | | Hannover | 1 - 0 | Viktoria Ber |
| 30 Jun 21 |
r03 | | Lokomotiv Pl | 1 - 2 | Beroe |
| 30 Jun 21 |
r03 | | Pardubice | 1 - 1 | Mlada Bolesl |
| 30 Jun 21 |
r03 | | Lech Poznan | 3 - 1 | Zaglebie Lub |
| 30 Jun 21 |
r03 | | HNK Gorica | 1 - 1 | Uta Arad |
| 30 Jun 21 |
r03 | | Ajaccio | 2 - 1 | FC Bastia-Bo |
| 30 Jun 21 |
r03 | | Dynamo Česk | 0 - 4 | Dinamo Mosco |
| 30 Jun 21 |
r03 | | FK Pohronie | 3 - 2 | ViOn Zlaté |
| 30 Jun 21 |
r03 | | Standard | 0 - 0 | St. Gilloise |
| 30 Jun 21 |
r03 | | Club Brugge | 2 - 1 | NK Lokomotiv |
| 30 Jun 21 |
r03 | | NŠ Mura | - | Arges Pitest |
| 30 Jun 21 |
r03 | | Olympiakos | 2 - 1 | CSKA Sofia |
| 30 Jun 21 |
r03 | | Germania Hal | 0 - 6 | Hallescher F |
| 30 Jun 21 |
r03 | | Spartak Subo | 2 - 2 | Radnik Surdu |
| 30 Jun 21 |
r03 | | NŠ Mura | 1 - 1 | Vojvodina |
| 30 Jun 21 |
r03 | | Szombathelyi | 1 - 1 | Zalaegerszeg |
| 30 Jun 21 |
r03 | | Šibenik | 0 - 1 | TSC Bačka T |
| 30 Jun 21 |
r03 | | Luckenwalde | 5 - 1 | Union Fürst |
| 30 Jun 21 |
r03 | | Paksi FC | 7 - 2 | III Kerület |
| 30 Jun 21 |
r03 | | Rijeka | 2 - 2 | MSK Zilina |
| 30 Jun 21 |
r03 | | Lucerne | 2 - 4 | SC Kriens |
| 30 Jun 21 |
r03 | | Novi Pazar | 0 - 0 | Rudar Pljevl |
| 30 Jun 21 |
r03 | | Zlatibor Ča | 0 - 3 | Mladost Luč |
| 30 Jun 21 |
r03 | | TSV Hartberg | 0 - 0 | SK Vorwarts |
| 30 Jun 21 |
r03 | | Oldenburg | 0 - 4 | Werder Breme |
| 30 Jun 21 |
r03 | | Bahlinger SC | 0 - 0 | Karlsruhe |
| 30 Jun 21 |
r03 | | Chemie Leipz | 1 - 7 | Zwickau |
| 30 Jun 21 |
r03 | | Slovan Brati | 1 - 1 | Zlín |
| 01 Jul 21 |
r03 | | Metaloglobus | - | Zorya |
| 01 Jul 21 |
r03 | | F.C. Paços | - | Varzim |
| 01 Jul 21 |
r03 | | Torpedo Mosc | 2 - 0 | Dynamo Bryan |
| 01 Jul 21 |
r03 | | Harrogate To | 0 - 5 | Doncaster |
| 01 Jul 21 |
r03 | | Steaua Bucur | 4 - 1 | Concordia |
| 01 Jul 21 |
r03 | | Eintracht No | 2 - 4 | Berliner AK |
| 01 Jul 21 |
r03 | | Lask Juniors | 2 - 5 | Wuerzburger |
| 01 Jul 21 |
r03 | | NK Maribor | 1 - 3 | Cracovia Kra |
| 01 Jul 21 |
r03 | | Domzale | 3 - 2 | Tuzla City |
| 01 Jul 21 |
r04 | | Birkirkara | 2 - 1 | Mosta FC |
| 01 Jul 21 |
r04 | | Stafford Ran | 2 - 1 | TNS |
| 01 Jul 21 |
r03 | | SGI | 0 - 1 | Esbjerg |
| 01 Jul 21 |
r03 | | AGF Aarhus | 3 - 2 | HOBRO |
| 01 Jul 21 |
r03 | | Herstedøste | 0 - 5 | Brøndby |
| 01 Jul 21 |
r03 | | AGF Aarhus | - | FC Midtjylla |
| 01 Jul 21 |
r03 | | Sparta Pragu | 1 - 0 | Líšeň |
| 01 Jul 21 |
r03 | | Slavia Sofia | 1 - 2 | Hebar Pazard |
| 01 Jul 21 |
r03 | | Arsenal Tula | 1 - 3 | Cukaricki |
| 01 Jul 21 |
r03 | | FC Krasnodar | 1 - 2 | Sepsi OSK Sf |
| 01 Jul 21 |
r03 | | Puskás Akad | 2 - 0 | FC Spartak T |
| 01 Jul 21 |
r03 | | NŠ Mura | 0 - 4 | FK Rostov |
| 01 Jul 21 |
r03 | | Crvena Zvezd | 2 - 1 | Aris |
| 01 Jul 21 |
r03 | | Osijek | 1 - 1 | Videoton FC |
| 01 Jul 21 |
r03 | | FC Basel | 4 - 4 | Dynamo Kiev |
| 02 Jul 21 |
r03 | | Austria Klag | - | FC BW Linz |
| 02 Jul 21 |
r03 | | Atlético Na | 2 - 2 | Jaguares de |
| 02 Jul 21 |
r03 | | Rapid Bucure | 2 - 1 | CS Mioveni |
| 02 Jul 21 |
r03 | | Anderlecht | - | KV Oostende |
| 02 Jul 21 |
r03 | | Lyngby | 2 - 3 | Nykøbing |
| 02 Jul 21 |
r03 | | Sønderjyske | - | Viborg |
| 02 Jul 21 |
r03 | | FC Wil | 1 - 2 | Grasshoppers |
| 02 Jul 21 |
r03 | | Cherno More | 4 - 3 | Beroe |
| 02 Jul 21 |
r03 | | Vitesse | 1 - 3 | NK Lokomotiv |
| 02 Jul 21 |
r03 | | Yverdon Spor | 2 - 4 | FC Sion |
| 02 Jul 21 |
r03 | | Zlatibor Ča | 2 - 3 | Metalac GM |
| 02 Jul 21 |
r03 | | FC Lviv | 2 - 1 | Veres Rivne |
| 02 Jul 21 |
r03 | | SC Dnipro-1 | 1 - 1 | FC Olexandri |
| 02 Jul 21 |
r03 | | Tekstilshchi | 0 - 3 | FC Yenisey K |
| 02 Jul 21 |
r03 | | Újpest FC | 1 - 0 | FC Voluntari |
| 02 Jul 21 |
r03 | | Dinamo Mosco | 1 - 0 | AEL Limassol |
| 02 Jul 21 |
r03 | | Apollon Lima | - | Anorthosis F |
| 02 Jul 21 |
r03 | | Celje | 0 - 0 | Universitate |
| 02 Jul 21 |
r03 | | Domzale | 2 - 1 | Šibenik |
| 02 Jul 21 |
r03 | | Nieciecza | 2 - 3 | Hapoel Beer |
| 02 Jul 21 |
r03 | | Osnabrueck | 7 - 3 | SSV Jeddeloh |
| 02 Jul 21 |
r03 | | Universitari | - | CC Deportivo |
| 02 Jul 21 |
r03 | | Kolding IF | 3 - 2 | Jammerbugt |
| 02 Jul 21 |
r03 | | Glentoran | 3 - 0 | Dundela |
| 02 Jul 21 |
r03 | | Civil Servic | 3 - 5 | Hibernian |
| 02 Jul 21 |
r03 | | FC Braşov | - | CS Mioveni |
| 02 Jul 21 |
r03 | | AC Horsens | 0 - 0 | Silkeborg IF |
| 02 Jul 21 |
r03 | | Mechelen | - | St.Truiden |
| 02 Jul 21 |
r03 | | Nizhny Novgo | 0 - 3 | FK Rubin Kaz |
| 02 Jul 21 |
r03 | | SC Heracles | 1 - 2 | Sparta |
| 02 Jul 21 |
r03 | | FC Wil | - | Vaduz |
| 02 Jul 21 |
r03 | | FC U Craiova | 0 - 1 | SV Horn |
| 02 Jul 21 |
r03 | | Sturm Graz | 9 - 1 | FC Liefering |
| 02 Jul 21 |
r03 | | Holstein Kie | 1 - 2 | Randers FC |
| 02 Jul 21 |
r03 | | Pogon Szczec | 2 - 1 | Warta Pozna� |
| 02 Jul 21 |
r03 | | FC Wil | 7 - 1 | Austria Lust |
| 02 Jul 21 |
r03 | | Le Havre | 0 - 2 | Amiens |
| 02 Jul 21 |
r03 | | Valenciennes | 0 - 0 | USL Dunkerqu |
| 02 Jul 21 |
r03 | | SV Josko Rie | 1 - 0 | Munich 1860 |
| 02 Jul 21 |
r03 | | Gazovik Oren | 2 - 2 | Slovacko |
| 02 Jul 21 |
r03 | | Spartak Mosc | 2 - 2 | NK Bravo |
| 02 Jul 21 |
r03 | | Sturm Graz | 1 - 3 | FC BW Linz |
| 02 Jul 21 |
r03 | | Dijon | 1 - 2 | Sochaux |
| 02 Jul 21 |
r03 | | Olympiakos | 1 - 1 | FC Ufa |
| 02 Jul 21 |
r03 | | Waregem | 1 - 2 | Cercle Brugg |
| 03 Jul 21 |
r03 | | Vlašim | 1 - 1 | Vysočina Ji |
| 03 Jul 21 |
r03 |  | Diosgyor | 3 - 2 | Kisvárda FC |
| 03 Jul 21 |
r03 | | Gyirmót | 1 - 0 | III Kerület |
| 03 Jul 21 |
r03 | | Gaz Metan Me | 0 - 1 | FC Hermannst |
| 03 Jul 21 |
r03 | | Chayka Pesch | - | PFC Spartak |
| 03 Jul 21 |
r03 | | Thun | 3 - 0 | Stade Lausan |
| 03 Jul 21 |
r03 | | Guimaraes | 2 - 1 | Feirense |
| 03 Jul 21 |
r03 | | SC Heerenvee | 3 - 1 | Jong Utrecht |
| 03 Jul 21 |
r03 | | VfB Auerbach | 1 - 1 | SpVgg Greuth |
| 03 Jul 21 |
r03 | | Karlsruhe | 5 - 1 | Viktoria Kö |
| 03 Jul 21 |
r03 | | FC Eilenburg | 0 - 5 | Hallescher F |
| 03 Jul 21 |
r03 | | East Kilbrid | 1 - 2 | Partick |
| 03 Jul 21 |
r03 | | Antwerp | - | FC Utrecht |
| 03 Jul 21 |
r03 | | Sportfreunde | 0 - 2 | SV Meppen |
| 03 Jul 21 |
r03 | | Linfield | 0 - 3 | St Mirren |
| 03 Jul 21 |
r03 | | Altona 93 | 1 - 2 | Randers FC |
| 03 Jul 21 |
r03 | | Magdeburg | 3 - 3 | Viktoria Ber |
| 03 Jul 21 |
r03 | | SC Verl | 3 - 0 | Bielefeld |
| 03 Jul 21 |
r03 | | Beerschot VA | 0 - 1 | Duisburg |
| 03 Jul 21 |
r03 | | Brechin City | 1 - 4 | Dundee Unite |
| 03 Jul 21 |
r03 | | Raith Rvs | 2 - 2 | Queens Park |
| 03 Jul 21 |
r03 | | Queen of Sou | 2 - 1 | Stranraer |
| 03 Jul 21 |
r03 | | Chindia Târ | 1 - 3 | Steaua Bucur |
| 03 Jul 21 |
r03 | | Uzhhorod | 3 - 2 | Vorskla |
| 03 Jul 21 |
r03 | | Larne | 2 - 2 | Kilmarnock |
| 03 Jul 21 |
r03 | | Eupen | 1 - 1 | FC Saarbrüc |
| 03 Jul 21 |
r03 | | Elgin City | 0 - 5 | Ross County |
| 03 Jul 21 |
r03 | | Farul Consta | 0 - 1 | Petrolul |
| 03 Jul 21 |
r03 | | Braunschweig | 0 - 1 | Dynamo Dresd |
| 03 Jul 21 |
r03 | | Grödig | 0 - 0 | SK Vorwarts |
| 03 Jul 21 |
r03 | | Livingston | 3 - 0 | East Stirlin |
| 03 Jul 21 |
r03 | | Hearts | 4 - 0 | Falkirk |
| 03 Jul 21 |
r03 | | Cusco FC | 1 - 2 | Universidad |
| 03 Jul 21 |
r03 | | Caen | 1 - 0 | AS Beauvais |
| 03 Jul 21 |
r03 | | Voždovac | 0 - 0 | Rudar Pljevl |
| 03 Jul 21 |
r03 | | Chornomorets | 2 - 0 | Balkany |
| 03 Jul 21 |
r03 | | Leon | 0 - 3 | Necaxa |
| 03 Jul 21 |
r03 | | WSG Swarovsk | 0 - 1 | FC Botoșani |
| 03 Jul 21 |
r03 | | Dobrudzha | - | Pirin Blagoe |
| 03 Jul 21 |
r03 | | Viktoria Plz | - | Aue |
| 03 Jul 21 |
r03 | | Levski Sofia | 1 - 1 | Botev Plovdi |
| 03 Jul 21 |
r03 | | Atlético Na | 0 - 0 | Rionegro Ág |
| 03 Jul 21 |
r03 | | KAMAZ Nabere | 1 - 1 | FC Chelyabin |
| 03 Jul 21 |
r03 | | Radnik Surdu | 2 - 2 | Sloboda |
| 03 Jul 21 |
r03 | | VV Katwijk | 1 - 2 | Jong AZ |
| 03 Jul 21 |
r03 | | Wisla Plock | 1 - 1 | Omonia Nicos |
| 03 Jul 21 |
r03 | | FC Krasnodar | 1 - 2 | PFC Kuban Kr |
| 03 Jul 21 |
r03 | | Alloa | 0 - 0 | Morton |
| 03 Jul 21 |
r03 | | Cruz Azul | 1 - 1 | FC Juarez |
| 03 Jul 21 |
r03 | | Debrecen | 3 - 1 | Tiszakécske |
| 03 Jul 21 |
r03 | | Nice | 1 - 1 | Rodez AF |
| 03 Jul 21 |
r03 | | Auxerre | 3 - 0 | Epinal |
| 03 Jul 21 |
r03 | | Tabor Sežan | 4 - 5 | Radnički Ni |
| 03 Jul 21 |
r03 | | Tijuana | 3 - 3 | Pachuca |
| 03 Jul 21 |
r01 | | Ajax | 6 - 0 | Koninklijke |
| 03 Jul 21 |
r03 | | Alianza Lima | - | FBC Melgar |
| 03 Jul 21 |
r01 | | Feyenoord | 3 - 1 | AEK |
| 03 Jul 21 |
r03 | | Arda Kardzha | - | Botev Vratsa |
| 03 Jul 21 |
r04 | | Sozopol | 1 - 2 | Spartak Varn |
| 03 Jul 21 |
r04 | | FC Ryazan | 7 - 2 | FC Znamya Tr |
| 03 Jul 21 |
r04 | | Carshalton A | 3 - 1 | Walton Casua |
| 03 Jul 21 |
r04 | | Dorking Wand | 1 - 0 | Kingstonian |
| 03 Jul 21 |
r04 | | Folkestone I | 3 - 1 | Welling Unit |
| 03 Jul 21 |
r04 | | Limavady Uni | 4 - 2 | Ballinamalla |
| 03 Jul 21 |
r04 | | Staines Town | 1 - 1 | Farnborough |
| 03 Jul 21 |
r04 | | The Spartans | 1 - 5 | Stenhousemui |
| 03 Jul 21 |
r03 | | FC Krasnodar | 1 - 0 | FC Chernomor |
| 03 Jul 21 |
r04 | | Botev Plovdi | 1 - 2 | Maritsa Plov |
| 03 Jul 21 |
r03 | | SKN St. Polt | - | Arges Pitest |
| 03 Jul 21 |
r03 | | Radnik Surdu | - | Mornar |
| 03 Jul 21 |
r03 | | KFUM Roskild | - | Køge |
| 03 Jul 21 |
r03 | | Farul Consta | 1 - 1 | Csikszereda |
| 03 Jul 21 |
r03 | | Arda Kardzha | 1 - 1 | Strumska Sla |
| 03 Jul 21 |
r03 | | Chrudim | 3 - 1 | Viktoria Ži |
| 03 Jul 21 |
r03 | | Vizela | 2 - 3 | Gil Vicente |
| 03 Jul 21 |
r04 | | Borec | 0 - 2 | Bregalnica � |
| 03 Jul 21 |
r03 | | Moreirense | 1 - 0 | F.C. Paços |
| 03 Jul 21 |
r03 | | Kolubara | 4 - 1 | Rudar Pljevl |
| 03 Jul 21 |
r03 | | Jablonec | 2 - 0 | Varnsdorf |
| 03 Jul 21 |
r03 | | VfR Garching | 0 - 6 | Nurnberg II |
| 03 Jul 21 |
r04 | | ACS Sirineas | 0 - 2 | Slatina |
| 03 Jul 21 |
r03 | | Proleter Nov | - | Mariupol |
| 03 Jul 21 |
r03 | | Septemvri Si | 1 - 2 | CSKA 1948 |
| 03 Jul 21 |
r03 |  | Sigma Olomou | 2 - 0 | Zbrojovka Br |
| 03 Jul 21 |
r03 | | SFC Opava | 0 - 1 | Karvina |
| 03 Jul 21 |
r03 | | Táborsko | 2 - 1 | Dynamo Česk |
| 03 Jul 21 |
r03 | | LKS Lodz | 2 - 0 | Stal Mielec |
| 03 Jul 21 |
r03 | | Banik Ostrav | 3 - 0 | Prostějov |
| 03 Jul 21 |
r03 | | Gornik Zabrz | 3 - 0 | Puszcza Niep |
| 03 Jul 21 |
r03 | | Liberec | 3 - 1 | Sparta Pragu |
| 03 Jul 21 |
r03 | | Osijek | 0 - 0 | Zalaegerszeg |
| 03 Jul 21 |
r03 | | Neftekhimik | 3 - 1 | Spartak-2 Mo |
| 03 Jul 21 |
r03 | | Paksi FC | 5 - 2 | Pécs |
| 03 Jul 21 |
r03 | | Mlada Bolesl | 2 - 0 | Pribram |
| 03 Jul 21 |
r03 | | FK Pohronie | 2 - 1 | Kosice |
| 03 Jul 21 |
r03 | | SSV Jeddeloh | 1 - 4 | VfL Oldenbur |
| 03 Jul 21 |
r03 | | Zlín | 1 - 1 | Trencin |
| 03 Jul 21 |
r03 | | Jagiellonia | 0 - 2 | Legia Warsaw |
| 03 Jul 21 |
r03 | | Zurich | 0 - 1 | FC Aarau |
| 03 Jul 21 |
r03 | | Piast Gliwic | 3 - 0 | Sandecja Now |
| 03 Jul 21 |
r03 | | Korona Kielc | 3 - 2 | Zaglebie Sos |
| 03 Jul 21 |
r03 | | Union Fürst | 3 - 2 | Lichtenberg |
| 03 Jul 21 |
r03 | | Odense BK | 7 - 0 | Fremad Amage |
| 03 Jul 21 |
r03 | | Teplice | - | Bohemians 19 |
| 03 Jul 21 |
r03 | | FC Winterthu | 1 - 3 | Lucerne |
| 03 Jul 21 |
r03 | | Pardubice | 3 - 1 | Dukla Praha |
| 03 Jul 21 |
r03 | | Sigma Olomou | 2 - 1 | ŠKF Sereď |
| 03 Jul 21 |
r03 | | Viktoria Asc | - | Wehen Wiesba |
| 03 Jul 21 |
r03 | | Jahn Regensb | 4 - 0 | SpVgg Bayreu |
| 03 Jul 21 |
r03 | | Hannover II | 1 - 2 | Chemnitzer F |
| 03 Jul 21 |
r03 | | Go Ahead Eag | 1 - 1 | RKC Waalwijk |
| 03 Jul 21 |
r03 | | Banik Ostrav | 2 - 2 | Třinec |
| 03 Jul 21 |
r03 | | Vejle Boldkl | 1 - 1 | AaB |
| 03 Jul 21 |
r03 | | Wacker Innsb | 1 - 3 | Nurnberg |
| 03 Jul 21 |
r03 | | Schwarz-Wei� | 0 - 5 | Osnabrueck |
| 03 Jul 21 |
r03 | | Hannover | 1 - 1 | Paderborn |
| 03 Jul 21 |
r03 | | Hansa Rostoc | 3 - 1 | Luckenwalde |
| 03 Jul 21 |
r03 | | Eintracht Ce | 3 - 1 | Tennis Borus |
| 03 Jul 21 |
r03 | | FC Lausanne- | 1 - 1 | Dynamo Kiev |
| 03 Jul 21 |
r03 | | Thun | 1 - 2 | SC Kriens |
| 03 Jul 21 |
r03 | | Lech Poznan | 0 - 1 | Lechia Gdań |
| 03 Jul 21 |
r01 | | PSV Eindhove | 6 - 2 | Molenbeek |
| 03 Jul 21 |
r03 | | St Pauli | - | PEC Zwolle |
| 03 Jul 21 |
r03 | | Kelty Hearts | 1 - 1 | Montrose |
| 03 Jul 21 |
r03 | | Berliner FC | 5 - 1 | Eintracht No |
| 03 Jul 21 |
r03 | | Wolfsberger | 1 - 3 | Rijeka |
| 03 Jul 21 |
r03 | | Spennymoor T | 2 - 2 | Sunderland |
| 03 Jul 21 |
r03 | | Hitchin Town | 0 - 7 | Luton |
| 03 Jul 21 |
r03 | | AZ Alkmaar | 4 - 1 | NEC Nijmegen |
| 03 Jul 21 |
r03 | | Chrudim | - | Vlašim |
| 03 Jul 21 |
r03 | | Schalke 04 | 0 - 0 | Zenit St Pet |
| 03 Jul 21 |
r03 | | Olympiakos | 2 - 0 | FC U Craiova |
| 03 Jul 21 |
r03 | | SC Rheindorf | 1 - 3 | St. Gallen |
| 03 Jul 21 |
r03 | | Clyde | 3 - 1 | Albion Rover |
| 03 Jul 21 |
r03 | | SV Salzburg | 1 - 3 | Monaco |
| 03 Jul 21 |
r03 | | Rapid Vienna | 0 - 0 | Lok. Moscow |
| 03 Jul 21 |
r03 | | Chemie Leipz | 4 - 1 | Beitar Jerus |
| 03 Jul 21 |
r03 | | Standard | 3 - 2 | Cercle Brugg |
| 03 Jul 21 |
r03 | | Tsarsko Selo | 0 - 0 | Lokomotiv So |
| 03 Jul 21 |
r03 | | Servette | 2 - 2 | Neuchâtel X |
| 03 Jul 21 |
r03 | | Troyes | 1 - 2 | Clermont Foo |
| 03 Jul 21 |
r03 | | Tatran Lipto | 1 - 3 | Wisla Krakow |
| 03 Jul 21 |
r03 | | LASK | 3 - 0 | Dinamo Mosco |
| 03 Jul 21 |
r03 | | TSV Hartberg | 3 - 2 | SV Lafnitz |
| 03 Jul 21 |
r03 | | DAC 1904 Dun | 4 - 2 | Szombathelyi |
| 03 Jul 21 |
r03 | | HNK Gorica | 0 - 2 | Vojvodina |
| 03 Jul 21 |
r03 | | Quevilly | 0 - 3 | Ajaccio |
| 03 Jul 21 |
r03 | | Club Brugge | 0 - 1 | Kortrijk |
| 03 Jul 21 |
r03 | | NK Aluminij | 1 - 2 | Uta Arad |
| 04 Jul 21 |
r04 | | FC Zenit Pen | - | FC Sokol Sar |
| 04 Jul 21 |
r03 | | Partizan Bel | 3 - 0 | Cracovia Kra |
| 04 Jul 21 |
r03 | | Aris | 1 - 3 | Hajduk Split |
| 04 Jul 21 |
r03 | | Fortuna Düs | - | Wuerzburger |
| 04 Jul 21 |
r03 | | SKN St. Polt | 1 - 2 | FC Voluntari |
| 04 Jul 21 |
r03 | | Kaiserslaute | 1 - 1 | Unterhaching |
| 04 Jul 21 |
r03 | | FC Yenisey K | 0 - 0 | Metallurg Li |
| 04 Jul 21 |
r03 | | Helsingborg | - | Fremad Amage |
| 04 Jul 21 |
r03 | | Paderborn | 2 - 4 | Dortmund II |
| 04 Jul 21 |
r03 | | Hebar Pazard | 0 - 3 | Botev Vratsa |
| 04 Jul 21 |
r03 | | Envigado F.C | 2 - 0 | Jaguares de |
| 04 Jul 21 |
r03 | | Rukh Lviv | 2 - 1 | Volyn |
| 04 Jul 21 |
r03 | | Resovia Rzes | 2 - 1 | Hapoel Beer |
| 04 Jul 21 |
r03 | | Mladost Luč | 1 - 0 | Spartak Subo |
| 04 Jul 21 |
r04 | | FC Torpedo V | 2 - 3 | FC Khimik Dz |
| 04 Jul 21 |
r03 | | Lokomotiv Pl | - | Yantra Gabro |
| 04 Jul 21 |
r03 | | Morelia | 1 - 3 | Pumas |
| 04 Jul 21 |
r03 | | TuS Dassendo | 2 - 6 | Holstein Kie |
| 04 Jul 21 |
r03 | | Werder Breme | 1 - 0 | CSKA Sofia |
| 04 Jul 21 |
r03 | | Clitheroe | 0 - 3 | Accrington |
| 04 Jul 21 |
r03 | | Sloboda | 1 - 1 | Novi Pazar |
| 04 Jul 21 |
r03 | | Austria Vien | - | FC Ashdod |
| 04 Jul 21 |
r03 | | Rakow Czesto | 2 - 1 | Shakhtar Don |
| 04 Jul 21 |
r03 | | Olimpija Lju | 1 - 2 | Cukaricki |
| 04 Jul 21 |
r03 | | Bastia | 1 - 0 | FC Bastia-Bo |
| 04 Jul 21 |
r03 | | TSC Bačka T | 2 - 4 | Tuzla City |
| 05 Jul 21 |
r03 | | Patriotas Bo | 1 - 3 | Once Caldas |
| 05 Jul 21 |
r03 | | Rio Grande V | 1 - 5 | Monterrey |
| 05 Jul 21 |
r03 | | FC Lviv | 1 - 2 | Prykarpattia |
| 05 Jul 21 |
r03 | | Esbjerg | 5 - 2 | HOBRO |
| 05 Jul 21 |
r03 | | FC Yenisey K | 2 - 2 | FC Tver |
| 05 Jul 21 |
r03 | | FC Ufa | 1 - 3 | Sepsi OSK Sf |
| 05 Jul 21 |
r03 | | Cracovia Kra | 2 - 2 | Lok. Moscow |
| 05 Jul 21 |
r03 | | AEL Limassol | 0 - 0 | FC Voluntari |
| 05 Jul 21 |
r03 | | Partick | 0 - 1 | Rangers |
| 05 Jul 21 |
r03 | | Helsingborg | 2 - 1 | FC Helsingoe |
| 05 Jul 21 |
r03 | | Triglav Kran | 2 - 3 | FC Ashdod |
| 05 Jul 21 |
r03 | | Livingston | 4 - 0 | Arbroath |
| 05 Jul 21 |
r04 | | Grays | 2 - 3 | Cray Valley |
| 05 Jul 21 |
r03 | | Santos | 0 - 1 | CF America |
| 05 Jul 21 |
r03 | | Spartak Mosc | 4 - 2 | Šibenik |
| 05 Jul 21 |
r03 | | FK Rubin Kaz | - | Ural S.R |
| 05 Jul 21 |
r03 | | Türkgücü | 1 - 2 | Shakhtar Don |
| 05 Jul 21 |
r03 | | Crvena Zvezd | 3 - 0 | Arges Pitest |
| 05 Jul 21 |
r03 | | CSKA Moscow | 0 - 1 | FC Copenhage |
| 06 Jul 21 |
r03 | | Apollon Lima | - | FC Heidenhei |
| 06 Jul 21 |
r03 | | Dijon | 1 - 1 | Grenoble |
| 06 Jul 21 |
r03 | | Sandhausen | 1 - 0 | FC Botoșani |
| 06 Jul 21 |
r03 | | Vizela | 3 - 4 | Braga |
| 06 Jul 21 |
r03 | | NK Bravo | 1 - 1 | MTK Hungaria |
| 06 Jul 21 |
r03 | | Beroe | - | Hebar Pazard |
| 06 Jul 21 |
r03 | | FC Heidenhei | 4 - 2 | SV Josko Rie |
| 06 Jul 21 |
r03 | | CSKA 1948 | 1 - 1 | Inhulets |
| 06 Jul 21 |
r04 | | FC Zenit-Izh | 0 - 2 | FC Chelyabin |
| 06 Jul 21 |
r03 | | Botev Vratsa | 0 - 2 | Beroe |
| 06 Jul 21 |
r03 | | Radnik Surdu | - | Sloboda |
| 06 Jul 21 |
r03 | | Santa Clara | 0 - 0 | Feirense |
| 06 Jul 21 |
r03 | | Vorskla | 4 - 0 | Karpaty |
| 06 Jul 21 |
r03 | | Pardubice | 3 - 1 | Viktoria Ži |
| 06 Jul 21 |
r03 | | Kortrijk | 0 - 1 | Valenciennes |
| 06 Jul 21 |
r03 | | Accrington | 1 - 0 | Hibernian |
| 06 Jul 21 |
r03 | | St. Gilloise | 6 - 2 | KMSK Deinze |
| 06 Jul 21 |
r03 | | Wolfsburg | 2 - 1 | Aue |
| 06 Jul 21 |
r03 | | Montana | 2 - 1 | Academica Cl |
| 06 Jul 21 |
r03 | | Lechia Gdań | 2 - 0 | Stomil Olszt |
| 06 Jul 21 |
r03 | | SC Farense | 0 - 1 | Varzim |
| 06 Jul 21 |
r03 | | Opatija | 0 - 0 | NK Istra 196 |
| 06 Jul 21 |
r03 | | AFC Fylde | - | Barnsley |
| 06 Jul 21 |
r03 | | Cumbernauld | 0 - 2 | Morton |
| 06 Jul 21 |
r04 | | Witton | 1 - 3 | Macclesfield |
| 06 Jul 21 |
r04 | | Broxburn Ath | 2 - 1 | East Stirlin |
| 06 Jul 21 |
r03 | | CS Mioveni | 3 - 2 | Slatina |
| 06 Jul 21 |
r03 | | Jagiellonia | 1 - 4 | Radomiak Rad |
| 06 Jul 21 |
r03 | | Arsenal Tula | 1 - 4 | Sparta Pragu |
| 06 Jul 21 |
r03 | | Austria Klag | 1 - 2 | Munich 1860 |
| 06 Jul 21 |
r03 | | FC Basel | 1 - 0 | Grasshoppers |
| 06 Jul 21 |
r03 |  | Jablonec | - | Pardubice |
| 06 Jul 21 |
r03 | | Dundee FC | 3 - 0 | Leyton Orien |
| 06 Jul 21 |
r03 | | Gornik Zabrz | 3 - 4 | Omonia Nicos |
| 06 Jul 21 |
r03 | | Young Boys | 0 - 1 | SC Rheindorf |
| 06 Jul 21 |
r03 | | HSC 21 | 0 - 2 | FC Twente |
| 06 Jul 21 |
r03 | | SV Venray | 0 - 4 | VVV-Venlo |
| 06 Jul 21 |
r03 | | Aylesbury | - | AFC Fylde |
| 06 Jul 21 |
r03 | | Luckenwalde | 0 - 1 | Hertha Zehle |
| 06 Jul 21 |
r03 | | Walton Casua | 0 - 3 | Crawley |
| 07 Jul 21 |
r03 | | Hapoel Beer | - | Omonia Nicos |
| 07 Jul 21 |
r03 | | Club Brugge | 2 - 1 | Waregem |
| 07 Jul 21 |
r03 | | Uta Arad | - | Zalaegerszeg |
| 07 Jul 21 |
r03 | | Beerschot VA | 2 - 0 | Waasland-Bev |
| 07 Jul 21 |
r03 | | Austria Vien | 2 - 1 | Tuzla City |
| 07 Jul 21 |
r03 | | CSKA Sofia | 0 - 1 | Qarabag FK |
| 07 Jul 21 |
r03 | | Tabor Sežan | 4 - 1 | Zalaegerszeg |
| 07 Jul 21 |
r03 | | Auxerre | 3 - 1 | Creteil |
| 07 Jul 21 |
r03 | | Caen | 1 - 1 | Guingamp |
| 07 Jul 21 |
r03 | | AZ Alkmaar | 3 - 0 | TOP Oss |
| 07 Jul 21 |
r03 | | HNK Gorica | 1 - 3 | NK Lokomotiv |
| 07 Jul 21 |
r03 | | Aris | 2 - 1 | Lok. Moscow |
| 07 Jul 21 |
r03 | | Celje | 3 - 0 | Hajduk Split |
| 07 Jul 21 |
r04 | | Pécs | 3 - 0 | Szeged-Csan� |
| 07 Jul 21 |
r03 | | Banik Ostrav | - | SFC Opava |
| 07 Jul 21 |
r04 | | CSA Steaua B | 6 - 0 | OFK Beograd |
| 07 Jul 21 |
r01 | | Feyenoord | 1 - 0 | Zurich |
| 07 Jul 21 |
r03 | | Pirin Blagoe | 1 - 0 | Spartak Varn |
| 07 Jul 21 |
r03 | | Lens | 1 - 1 | Standard |
| 07 Jul 21 |
r03 | | Rapid Vienna | 2 - 2 | SKN St. Polt |
| 07 Jul 21 |
r03 | | Líšeň | 2 - 1 | FK Senica |
| 07 Jul 21 |
r03 | | Toluca | 0 - 1 | FC Juarez |
| 07 Jul 21 |
r03 | | Veres Rivne | 0 - 1 | Ahrobiznes |
| 07 Jul 21 |
r03 | | Guimaraes | 2 - 1 | Sporting B |
| 07 Jul 21 |
r03 | | Levski Sofia | 4 - 0 | Lokomotiv So |
| 07 Jul 21 |
r03 | | Chindia Târ | 0 - 0 | Csikszereda |
| 07 Jul 21 |
r03 | | Steaua Bucur | 1 - 0 | CS Mioveni |
| 07 Jul 21 |
r03 | | Hansa Rostoc | 4 - 3 | Viktoria Ber |
| 07 Jul 21 |
r04 | | Tikveš | 3 - 1 | Rabotnichki |
| 07 Jul 21 |
r03 | | FC Kolos Kov | 2 - 0 | FC Olexandri |
| 07 Jul 21 |
r03 | | Lucerne | 3 - 3 | Dynamo Kiev |
| 07 Jul 21 |
r03 | | Kispest Honv | 1 - 1 | ŠKF Sereď |
| 07 Jul 21 |
r03 | | Wehen Wiesba | 1 - 0 | FC Schweinfu |
| 07 Jul 21 |
r03 | | QPR | 2 - 1 | Portsmouth |
| 07 Jul 21 |
r03 | | Genk | 2 - 0 | Eupen |
| 07 Jul 21 |
r03 | | Gornik Zabrz | 0 - 3 | Hapoel Beer |
| 07 Jul 21 |
r03 | | Jablonec | 1 - 1 | Sparta Pragu |
| 07 Jul 21 |
r03 | | Gyirmót | 1 - 0 | Szombathelyi |
| 07 Jul 21 |
r03 | | San Antonio | 2 - 4 | Queretaro FC |
| 07 Jul 21 |
r03 | | Benfica | 2 - 0 | Covilha |
| 07 Jul 21 |
r03 | | Independient | 3 - 1 | Once Caldas |
| 07 Jul 21 |
r03 | | Gil Vicente | 1 - 1 | Leixoes |
| 07 Jul 21 |
r03 | | Envigado F.C | 0 - 2 | Atlético Na |
| 07 Jul 21 |
r03 | | Universitate | - | Zalaegerszeg |
| 07 Jul 21 |
r03 | | Mornar | 0 - 0 | Mladost Luč |
| 07 Jul 21 |
r03 | | FC Lausanne- | - | Valenciennes |
| 07 Jul 21 |
r03 | | Jastrzębie | 1 - 1 | Ruch Chorzow |
| 07 Jul 21 |
r03 | | Zaglebie Lub | 1 - 1 | Miedz Legnic |
| 07 Jul 21 |
r03 | | Vlašim | 3 - 2 | Teplice |
| 07 Jul 21 |
r03 | | Zaglebie Sos | 1 - 3 | Karvina |
| 07 Jul 21 |
r03 | | Mornar | 4 - 1 | Novi Pazar |
| 07 Jul 21 |
r03 | | Wisla Plock | 0 - 2 | Widzew Lodz |
| 07 Jul 21 |
r03 | | Odense BK | 1 - 1 | Brøndby |
| 07 Jul 21 |
r03 | | Augsburg | 2 - 2 | Hamburg |
| 07 Jul 21 |
r03 | | Sigma Olomou | 2 - 0 | Tatran Lipto |
| 07 Jul 21 |
r03 | | Puszcza Niep | 2 - 3 | Wisla Krakow |
| 07 Jul 21 |
r00  | | Sheffield We | 1 - 3 | Celtic |
| 07 Jul 21 |
r03 | | Lech Poznan | 3 - 2 | FC Midtjylla |
| 07 Jul 21 |
r03 | | WSG Swarovsk | 3 - 3 | Rakow Czesto |
| 07 Jul 21 |
r03 | | Paksi FC | 5 - 0 | Budaörs |
| 07 Jul 21 |
r03 | | Tsarsko Selo | 4 - 0 | Litex Lovech |
| 07 Jul 21 |
r03 | | Mlada Bolesl | 5 - 0 | Trencin |
| 07 Jul 21 |
r03 | | Arda Kardzha | 1 - 0 | CSKA 1948 |
| 07 Jul 21 |
r03 | | FC Sion | 1 - 3 | FC Lausanne- |
| 07 Jul 21 |
r03 | | Yverdon Spor | 1 - 0 | Servette |
| 07 Jul 21 |
r03 | | Charleroi | 3 - 3 | Amiens |
| 07 Jul 21 |
r03 | | Quevilly | 0 - 1 | Le Havre |
| 07 Jul 21 |
r03 | | St.Truiden | 1 - 0 | Molenbeek |
| 07 Jul 21 |
r03 | | Union Fürst | 0 - 1 | Tennis Borus |
| 07 Jul 21 |
r03 | | TSV Hartberg | - | SV Kapfenber |
| 07 Jul 21 |
r03 | | Berliner FC | 3 - 1 | Lichtenberg |
| 07 Jul 21 |
r03 | | Wacker Innsb | - | Karlsruhe |
| 07 Jul 21 |
r03 | | Werder Breme | 2 - 2 | Zenit St Pet |
| 07 Jul 21 |
r03 | | Laval | 1 - 2 | Ajaccio |
| 07 Jul 21 |
r03 | | Cukaricki | 1 - 1 | FC Ashdod |
| 08 Jul 21 |
r03 | | Santa Clara | - | Famalicao |
| 08 Jul 21 |
r03 | | Pachuca | 1 - 2 | Cruz Azul |
| 08 Jul 21 |
r03 | | CF America | 1 - 0 | Atlas |
| 08 Jul 21 |
r03 | | Uta Arad | 0 - 1 | Hajduk Split |
| 08 Jul 21 |
r03 | | Aberdeen | 1 - 1 | Inverness C |
| 08 Jul 21 |
r03 | | Magdeburg | 1 - 1 | VSG Altglien |
| 08 Jul 21 |
r03 | | Kisvárda FC | 2 - 2 | Arges Pitest |
| 08 Jul 21 |
r04 | | VV Katwijk | 3 - 2 | FC Rijnvogel |
| 08 Jul 21 |
r03 | | Tigres | 0 - 0 | CD Guadalaja |
| 08 Jul 21 |
r03 | | Slovacko | - | Arges Pitest |
| 08 Jul 21 |
r03 | | Anorthosis F | - | Doxa Katokop |
| 08 Jul 21 |
r03 | | Casa Pia | 2 - 0 | Sønderjyske |
| 08 Jul 21 |
r03 | | Partizan Bel | 1 - 0 | FK Rostov |
| 08 Jul 21 |
r03 | | Fortuna Düs | 2 - 2 | AEL Limassol |
| 08 Jul 21 |
r03 | | Morelia | 2 - 3 | Tepatitlán |
| 08 Jul 21 |
r03 | | Universitate | 0 - 0 | Radnički Ni |
| 08 Jul 21 |
r03 | | Zwickau | 2 - 1 | Carl Zeiss J |
| 08 Jul 21 |
r03 | | Csikszereda | 2 - 3 | Gaz Metan Me |
| 08 Jul 21 |
r03 | | Sturm Graz | 0 - 1 | Cracovia Kra |
| 08 Jul 21 |
r03 | | Viktoria Plz | 1 - 1 | Sepsi OSK Sf |
| 08 Jul 21 |
r03 | | Zorya | 2 - 1 | Proleter Nov |
| 08 Jul 21 |
r03 | | Inhulets | 1 - 0 | Academica Cl |
| 08 Jul 21 |
r03 | | Mlada Bolesl | 4 - 0 | Ústí nad L |
| 08 Jul 21 |
r03 | | PEC Zwolle | 0 - 2 | FC Volendam |
| 08 Jul 21 |
r03 | | Sturm Graz | - | FK Rostov |
| 08 Jul 21 |
r03 | | Lugano | 0 - 0 | FC Winterthu |
| 08 Jul 21 |
r03 | | Triglav Kran | 1 - 3 | Rijeka |
| 08 Jul 21 |
r03 | | Annecy | 2 - 3 | Bastia |
| 08 Jul 21 |
r03 | | Sturm Graz | 1 - 1 | Crvena Zvezd |
| 09 Jul 21 |
r04 | | FC Khimik Dz | 1 - 2 | FC Torpedo V |
| 09 Jul 21 |
r04 | | FC Yessentuk | 1 - 2 | FC Biolog-No |
| 09 Jul 21 |
r04 | | FC Zenit-Izh | 2 - 0 | FK Spartak T |
| 09 Jul 21 |
r04 | | Matlock | 3 - 2 | Boston Unite |
| 09 Jul 21 |
r03 | | SKU Amstette | 5 - 2 | AEL Limassol |
| 09 Jul 21 |
r03 | | Lens | 0 - 1 | St. Gilloise |
| 09 Jul 21 |
r03 | | Landskrona | 1 - 1 | B.93 |
| 09 Jul 21 |
r03 | | FC Utrecht | 3 - 0 | Gent |
| 09 Jul 21 |
r03 | | Stoke | 1 - 1 | Hibernian |
| 09 Jul 21 |
r03 | | Lechia Gdań | 0 - 2 | Radomiak Rad |
| 09 Jul 21 |
r03 | | Gyirmót | 0 - 0 | Szolnok |
| 09 Jul 21 |
r03 | | Petrolul | 0 - 0 | Chindia Târ |
| 09 Jul 21 |
r03 | | Queretaro FC | 1 - 2 | Real España |
| 09 Jul 21 |
r03 | | La Equidad | 0 - 1 | Once Caldas |
| 09 Jul 21 |
r03 | | Korona Kielc | - | Nieciecza |
| 09 Jul 21 |
r03 | | Jong Utrecht | 3 - 0 | Almere City |
| 09 Jul 21 |
r03 | | Mainz | 2 - 1 | Wuerzburger |
| 09 Jul 21 |
r03 | | SPVGG Greuth | 0 - 1 | Bayern Munic |
| 09 Jul 21 |
r03 | | Universitari | 0 - 0 | Universidad |
| 09 Jul 21 |
r03 | | Cracovia Kra | 0 - 1 | Slovacko |
| 09 Jul 21 |
r03 | | Lorient | 0 - 0 | Concarneau |
| 09 Jul 21 |
r03 | | Vizela | 1 - 2 | F.C. Paços |
| 09 Jul 21 |
r03 | | Fortuna Köl | 0 - 4 | FC Koln |
| 09 Jul 21 |
r03 | | Vejle Boldkl | 5 - 1 | Esbjerg |
| 09 Jul 21 |
r03 | | FC Ufa | 2 - 1 | FC Botoșani |
| 09 Jul 21 |
r03 | | Varzim | 0 - 1 | Estrela Amad |
| 09 Jul 21 |
r03 | | Waasland-Bev | 0 - 2 | Lille |
| 09 Jul 21 |
r03 | | SCM Gloria B | 1 - 5 | Steaua Bucur |
| 09 Jul 21 |
r03 | | Dijon | 1 - 2 | Nancy |
| 09 Jul 21 |
r03 | | Stafford Ran | 2 - 0 | Port Vale |
| 09 Jul 21 |
r03 | | Sønderjyske | - | Braga |
| 09 Jul 21 |
r03 | | CSKA 1948 | 2 - 1 | Lokomotiv Pl |
| 09 Jul 21 |
r03 | | Mladost Luč | 0 - 3 | Radnik Surdu |
| 09 Jul 21 |
r03 | | Jagiellonia | 1 - 1 | Wigry Suwał |
| 09 Jul 21 |
r03 | | Mechelen | 2 - 2 | Roda JC |
| 09 Jul 21 |
r03 | | Dundee FC | 2 - 2 | West Ham |
| 09 Jul 21 |
r03 | | AaB | 1 - 0 | AGF Aarhus |
| 09 Jul 21 |
r03 | | Osters IF | 2 - 2 | Gais |
| 09 Jul 21 |
r03 | | Rijeka | 4 - 3 | MTK Hungaria |
| 09 Jul 21 |
r03 | | Lech Poznan | 0 - 2 | Arka Gdynia |
| 09 Jul 21 |
r03 | | FC BW Linz | 1 - 1 | Liberec |
| 09 Jul 21 |
r03 | | Wolfsberger | 3 - 2 | Sparta Pragu |
| 09 Jul 21 |
r03 | | FC Trenkwald | 0 - 1 | CSKA Moscow |
| 09 Jul 21 |
r03 | | DAC 1904 Dun | 2 - 1 | Vasas |
| 09 Jul 21 |
r03 | | Austria Klag | 2 - 2 | SV Lafnitz |
| 09 Jul 21 |
r03 | | SV Josko Rie | 0 - 2 | Jahn Regensb |
| 09 Jul 21 |
r03 | | TSV Hartberg | 0 - 1 | Lok. Moscow |
| 09 Jul 21 |
r03 | | SV Horn | - | FC Copenhage |
| 09 Jul 21 |
r03 | | Shakhtar Don | 0 - 0 | Schalke 04 |
| 09 Jul 21 |
r03 | | SC Rheindorf | 4 - 1 | Dornbirn |
| 09 Jul 21 |
r03 | | Club Brugge | 2 - 1 | AEK |
| 09 Jul 21 |
r03 | | Schwarz-Wei� | 1 - 3 | Rödinghause |
| 09 Jul 21 |
r03 | | Strasbourg | 0 - 1 | FC Basel |
| 09 Jul 21 |
r03 | | PAOK | 3 - 1 | NFC Volos |
| 09 Jul 21 |
r03 | | FC Groningen | - | FC Emmen |
| 09 Jul 21 |
r03 | | VVV-Venlo | 2 - 0 | VV UNA |
| 09 Jul 21 |
r03 | | Chesham Unit | - | Wycombe |
| 09 Jul 21 |
r03 | | Squires Gate | 0 - 7 | Blackpool |
| 09 Jul 21 |
r03 | | Tiverton Tow | 0 - 1 | Exeter |
| 10 Jul 21 |
r03 | | Levski Sofia | - | Pirin Blagoe |
| 10 Jul 21 |
r03 | | Moreirense | 0 - 4 | Braga |
| 10 Jul 21 |
r03 | | Banik Ostrav | 2 - 0 | Líšeň |
| 10 Jul 21 |
r03 | | Levski Sofia | 1 - 1 | Levski Lom |
| 10 Jul 21 |
r03 | | CS Mioveni | 2 - 1 | Astra |
| 10 Jul 21 |
r03 | | FC Kolos Kov | 1 - 0 | Avanhard |
| 10 Jul 21 |
r03 | | Zlín | 2 - 2 | Prostějov |
| 10 Jul 21 |
r03 | | Teplice | 2 - 2 | Táborsko |
| 10 Jul 21 |
r03 | | Stade Lausan | 0 - 3 | Yverdon Spor |
| 10 Jul 21 |
r03 | | Silkeborg IF | 5 - 1 | Hvidovre IF |
| 10 Jul 21 |
r03 | | Siófok | - | Zalaegerszeg |
| 10 Jul 21 |
r03 | | FC Liefering | 4 - 0 | Grödig |
| 10 Jul 21 |
r03 | | Vlašim | 1 - 3 | Dynamo Česk |
| 10 Jul 21 |
r03 | | Odra Opole | 0 - 0 | Ruch Chorzow |
| 10 Jul 21 |
r03 | | Wisla Plock | 3 - 0 | Skra Często |
| 10 Jul 21 |
r03 | | Køge | 3 - 0 | Nykøbing |
| 10 Jul 21 |
r03 | | Guimaraes | 2 - 1 | Mafra |
| 10 Jul 21 |
r03 | | GKS Katowice | 1 - 0 | Sandecja Now |
| 10 Jul 21 |
r03 | | MVV Maastric | - | Fortuna Sitt |
| 10 Jul 21 |
r03 | | Korona Kielc | 2 - 0 | Widzew Lodz |
| 10 Jul 21 |
r03 | | Górnik Polk | 0 - 0 | Slask Wrocla |
| 10 Jul 21 |
r03 | | Gil Vicente | 2 - 1 | Santa Clara |
| 10 Jul 21 |
r03 | | Tondela | - | Arouca |
| 10 Jul 21 |
r03 | | HOBRO | 2 - 0 | Aarhus Frema |
| 10 Jul 21 |
r03 | | Zwickau | 2 - 0 | ZFC Meuselwi |
| 10 Jul 21 |
r03 | | Holstein Kie | 1 - 1 | Brøndby |
| 10 Jul 21 |
r03 | | Fremad Amage | 3 - 2 | Hellerup IK |
| 10 Jul 21 |
r03 | | Lyngby | 4 - 4 | FC Helsingoe |
| 10 Jul 21 |
r03 | | Tranmere | 1 - 0 | Rangers |
| 10 Jul 21 |
r03 | | TSV Havelse | 3 - 2 | Rot Weiss Ah |
| 10 Jul 21 |
r03 | | Chojniczanka | 3 - 1 | Stomil Olszt |
| 10 Jul 21 |
r03 | | VSG Altglien | - | Viktoria Ber |
| 10 Jul 21 |
r03 | | Motherwell | 0 - 2 | Millwall |
| 10 Jul 21 |
r03 | | Phönix Lüb | 1 - 0 | Tennis Borus |
| 10 Jul 21 |
r03 | | Reading | 1 - 0 | Lincoln |
| 10 Jul 21 |
r03 | | Sparta | 3 - 3 | Gent |
| 10 Jul 21 |
r03 | | Germania Hal | - | Hannover |
| 10 Jul 21 |
r03 | | Hannoversche | 2 - 1 | Germania Hal |
| 10 Jul 21 |
r03 | | Berliner AK | 0 - 2 | Hallescher F |
| 10 Jul 21 |
r03 | | TSV Aubstadt | 2 - 1 | FC Eilenburg |
| 10 Jul 21 |
r03 | | Jong PSV | 0 - 1 | FC Eindhoven |
| 10 Jul 21 |
r03 | | Bognor Regis | 0 - 3 | Burton |
| 10 Jul 21 |
r04 | | III Kerület | 3 - 3 | Budaörs |
| 10 Jul 21 |
r03 | | Nurnberg | 0 - 0 | FC Krasnodar |
| 10 Jul 21 |
r03 | | Waldhof Mann | - | Fola |
| 10 Jul 21 |
r03 | | TSV Steinbac | 5 - 1 | Bergisch Gla |
| 10 Jul 21 |
r03 | | Genk | 1 - 1 | FC Groningen |
| 10 Jul 21 |
r03 | | Amsterdamsch | 2 - 1 | NEC Nijmegen |
| 10 Jul 21 |
r03 | | SC Heerenvee | 2 - 2 | Kortrijk |
| 10 Jul 21 |
r03 | | IJsselmeervo | 1 - 3 | De Graafscha |
| 10 Jul 21 |
r04 | | Kaposvári R | - | Pécs |
| 10 Jul 21 |
r03 | | Oud-Heverlee | 1 - 0 | Valenciennes |
| 10 Jul 21 |
r03 | | Union Berlin | - | Dukla Praha |
| 10 Jul 21 |
r03 | | NAC Breda | 1 - 0 | Maccabi Tel |
| 10 Jul 21 |
r03 | | WSG Swarovsk | - | Nottingham F |
| 10 Jul 21 |
r03 | | Wolfsburg | 0 - 3 | Hansa Rostoc |
| 10 Jul 21 |
r03 | | Excelsior | - | Excelsior |
| 10 Jul 21 |
r03 | | FK Rubin Kaz | 1 - 0 | Khimki FK |
| 10 Jul 21 |
r03 | | Ein Frankfur | 1 - 3 | Wehen Wiesba |
| 10 Jul 21 |
r03 | | Guingamp | 2 - 2 | Brest |
| 10 Jul 21 |
r03 | | Chester City | 0 - 2 | Sheffield We |
| 10 Jul 21 |
r03 | | VfR Garching | - | Wacker Innsb |
| 10 Jul 21 |
r03 | | Necaxa | 0 - 0 | CS Herediano |
| 10 Jul 21 |
r03 | | Leon | 2 - 0 | Atletico de |
| 10 Jul 21 |
r03 | | Resovia Rzes | 3 - 1 | Kosice |
| 10 Jul 21 |
r03 | | Standard | 2 - 2 | Mechelen |
| 10 Jul 21 |
r03 | | Duisburg | 1 - 1 | FC Koln |
| 10 Jul 21 |
r03 | | Septemvri So | 0 - 2 | Beroe |
| 10 Jul 21 |
r03 | | SC Dnipro-1 | 1 - 1 | FC Kolos Kov |
| 10 Jul 21 |
r03 | | Beerschot VA | 2 - 1 | Lommel SK |
| 10 Jul 21 |
r03 | | SKN St. Polt | 1 - 0 | Bohemians 19 |
| 10 Jul 21 |
r03 | | Stade de Rei | 4 - 1 | Auxerre |
| 10 Jul 21 |
r03 | | Radnički 19 | 0 - 3 | Metalac GM |
| 10 Jul 21 |
r03 | | Farul Consta | 1 - 1 | Cherno More |
| 10 Jul 21 |
r03 | | Benfica | 3 - 2 | SC Farense |
| 10 Jul 21 |
r03 | | Tabor Sežan | 2 - 0 | Gorica |
| 10 Jul 21 |
r03 | | Novi Pazar | 1 - 0 | Rudar Pljevl |
| 10 Jul 21 |
r03 | | Portimonense | 0 - 1 | Covilha |
| 10 Jul 21 |
r03 | | Europa Point | 0 - 3 | Sheffield Un |
| 10 Jul 21 |
r03 | | SC Cambuur | 6 - 0 | SC Telstar |
| 10 Jul 21 |
r03 | | Montpellier | 2 - 4 | Sète 34 |
| 10 Jul 21 |
r03 | | Vojvodina | 0 - 0 | Maccabi Neta |
| 10 Jul 21 |
r03 | | Tigres | 0 - 1 | CF America |
| 10 Jul 21 |
r03 | | Lyon | 5 - 1 | Bourg-Peronn |
| 10 Jul 21 |
r03 | | WSG Swarovsk | 3 - 1 | Sandhausen |
| 10 Jul 21 |
r04 | | Marske Unite | - | Blyth Sparta |
| 10 Jul 21 |
r04 | | Ballyclare C | 2 - 0 | Limavady Uni |
| 10 Jul 21 |
r04 | | Portstewart | 1 - 3 | Knockbreda |
| 10 Jul 21 |
r04 | | Linlithgow R | 1 - 0 | Bo'ness Unit |
| 10 Jul 21 |
r04 | | Haringey Bor | 1 - 3 | Chelmsford |
| 10 Jul 21 |
r04 | | Folkestone I | 3 - 3 | Eastbourne B |
| 10 Jul 21 |
r04 | | Didcot Town | 0 - 4 | Hungerford T |
| 10 Jul 21 |
r04 | | Braintree To | 0 - 1 | Bishops Stor |
| 10 Jul 21 |
r04 | | Wimborne Tow | 4 - 0 | Christchurch |
| 10 Jul 21 |
r04 | | Hebar Pazard | 4 - 0 | Botev Plovdi |
| 10 Jul 21 |
r04 | | Sirens FC | 0 - 1 | Balzan FC |
| 10 Jul 21 |
r04 | | Akademija Pa | 2 - 0 | Rabotnichki |
| 10 Jul 21 |
r04 | | Šibenik | 0 - 2 | Posušje |
| 10 Jul 21 |
r04 | | Sloboda | 1 - 1 | Sloga Doboj |
| 10 Jul 21 |
r04 | | Javor Ivanji | 1 - 0 | Zlatibor Ča |
| 10 Jul 21 |
r04 | | Zrinjski | 1 - 0 | GOŠK Gabela |
| 10 Jul 21 |
r01 | | Ajax | 4 - 1 | Paderborn |
| 10 Jul 21 |
r01 | | Young Boys | 2 - 0 | Feyenoord |
| 10 Jul 21 |
r01 | | Galatasaray | 4 - 2 | Kasimpasa |
| 10 Jul 21 |
r02 | | Gaziantep FK | 3 - 2 | Istanbulspor |
| 10 Jul 21 |
r03 | | Wisla Plock | - | Radomiak Rad |
| 10 Jul 21 |
r03 | | Valenciennes | - | Bastia |
| 10 Jul 21 |
r03 | | SC Telstar | - | Jong Ajax |
| 10 Jul 21 |
r03 | | SC Cambuur | - | FC Twente |
| 10 Jul 21 |
r03 | | CS Mioveni | - | Petrolul |
| 10 Jul 21 |
r03 | | Atlético Na | - | Valledupar |
| 10 Jul 21 |
r03 | | Cusco FC | - | Academia Dep |
| 10 Jul 21 |
r03 | | Alianza Univ | - | FBC Melgar |
| 10 Jul 21 |
r03 | | Cienciano | - | CC Deportivo |
| 10 Jul 21 |
r03 | | San Antonio | 2 - 4 | Pumas |
| 10 Jul 21 |
r03 | | CS Mioveni | 3 - 2 | Slatina |
| 10 Jul 21 |
r03 | | Arda Kardzha | 0 - 1 | Slavia Sofia |
| 10 Jul 21 |
r03 | | Monaco | 3 - 1 | Cercle Brugg |
| 10 Jul 21 |
r03 | | Bergerac Pé | 0 - 1 | Bordeaux |
| 10 Jul 21 |
r03 | | Leixoes | 3 - 1 | Trofense |
| 10 Jul 21 |
r05 | | Osijek II | 1 - 0 | BSK Bijelo B |
| 10 Jul 21 |
r05 | | Szombathelyi | 1 - 1 | Ajka |
| 10 Jul 21 |
r05 | | Mezőkövesd | 4 - 0 | Tiszakécske |
| 10 Jul 21 |
r05 | | Pirin Blagoe | 6 - 1 | Neftochimic |
| 10 Jul 21 |
r05 | | Slavia Mozyr | 1 - 2 | Gomel |
| 10 Jul 21 |
r03 | | Banik Ostrav | - | FK Senica |
| 10 Jul 21 |
r03 | | Dukla Praha | 4 - 2 | Varnsdorf |
| 10 Jul 21 |
r03 | | Nice | 0 - 3 | FC Lausanne- |
| 10 Jul 21 |
r05 | | Universitate | 0 - 2 | Unirea Dej |
| 10 Jul 21 |
r05 | | Unirea Slobo | 0 - 1 | Metaloglobus |
| 10 Jul 21 |
r03 | | Dynamo Česk | - | Teplice |
| 10 Jul 21 |
r03 | | Vysočina Ji | 1 - 2 | Zbrojovka Br |
| 10 Jul 21 |
r03 | | SFC Opava | 2 - 1 | Tatran Lipto |
| 10 Jul 21 |
r03 | | Warta Pozna� | 1 - 2 | Gornik Zabrz |
| 10 Jul 21 |
r03 | | FC Sion | 3 - 1 | Sochaux |
| 10 Jul 21 |
r03 | | Hradec Král | 1 - 0 | Pribram |
| 10 Jul 21 |
r03 | | Chrudim | - | Mlada Bolesl |
| 10 Jul 21 |
r03 | | Zaglebie Sos | 1 - 2 | Podbeskidzie |
| 10 Jul 21 |
r05 | | Mlada Bolesl | 1 - 3 | Chrudim |
| 10 Jul 21 |
r03 | | Tychy 71 | 3 - 3 | Karvina |
| 10 Jul 21 |
r03 | | Vlašim | - | Táborsko |
| 10 Jul 21 |
r00   | | Paderborn | 1 - 4 | Ajax |
| 10 Jul 21 |
r05 | | Fortuna Sitt | - | MVV Maastric |
| 10 Jul 21 |
r05 | | Santa Clara | 1 - 2 | Gil Vicente |
| 10 Jul 21 |
r05 | | FC Utrecht | 1 - 1 | Anderlecht |
| 10 Jul 21 |
r03 | | AC Horsens | 2 - 0 | Kolding IF |
| 10 Jul 21 |
r03 | | Viborg | - | Randers FC |
| 10 Jul 21 |
r03 | | SC Heracles | - | Go Ahead Eag |
| 10 Jul 21 |
r05 | | Quick Boys | 2 - 5 | Willem II |
| 10 Jul 21 |
r03 | | Bochum | - | SC Verl |
| 10 Jul 21 |
r03 | | IFK Varnamo | 0 - 1 | Falkenbergs |
| 10 Jul 21 |
r03 | | Huddersfield | 1 - 0 | Harrogate To |
| 10 Jul 21 |
r03 | | St Pauli II | 4 - 1 | TuS Dassendo |
| 10 Jul 21 |
r03 | | AC Horsens | - | Aarhus Frema |
| 10 Jul 21 |
r03 | | Dartford | 0 - 1 | Ipswich |
| 10 Jul 21 |
r03 | | Welling Unit | 3 - 3 | Gillingham |
| 10 Jul 21 |
r03 | | Luton | 4 - 0 | Rochdale |
| 10 Jul 21 |
r03 | | Leamington | - | Coventry |
| 10 Jul 21 |
r03 | | Aue | 1 - 2 | Magdeburg |
| 10 Jul 21 |
r03 | | Chemie Leipz | 2 - 0 | SpVgg Greuth |
| 10 Jul 21 |
r03 | | Eintracht No | - | Bremer SV |
| 10 Jul 21 |
r05 | | Antwerp | 1 - 1 | FC Nordsjæl |
| 10 Jul 21 |
r05 | | FK Pirmasens | 2 - 2 | Viktoria Asc |
| 10 Jul 21 |
r03 | | Grasshoppers | 0 - 2 | Lucerne |
| 10 Jul 21 |
r03 | | SV Salzburg | - | Rakow Czesto |
| 10 Jul 21 |
r03 | | Amiens | 2 - 1 | KV Oostende |
| 10 Jul 21 |
r03 | | Bielefeld | 1 - 0 | Hannover |
| 10 Jul 21 |
r03 | | Freiburg | 2 - 1 | FC Saarbrüc |
| 10 Jul 21 |
r03 | | Waregem | 3 - 2 | Charleroi |
| 10 Jul 21 |
r03 | | VV UNA | - | FC Eindhoven |
| 10 Jul 21 |
r03 | | Stuttgart | 3 - 0 | St. Gallen |
| 10 Jul 21 |
r03 | | Willem II | 5 - 2 | Quick Boys |
| 10 Jul 21 |
r03 | | Schaffhausen | 1 - 1 | Freiburg II |
| 10 Jul 21 |
r03 | | Mönchenglad | 2 - 2 | Viktoria Kö |
| 10 Jul 21 |
r05 | | SV Babelsber | 1 - 3 | Hertha |
| 10 Jul 21 |
r05 | | Aberystwyth | 0 - 2 | Cardiff Metr |
| 10 Jul 21 |
r05 | | Nyva Ternopi | 1 - 0 | Rukh Lviv |
| 10 Jul 21 |
r05 | | Dorking Wand | 2 - 1 | Horsham |
| 10 Jul 21 |
r05 | | USL Dunkerqu | 3 - 0 | Mouscron-Per |
| 10 Jul 21 |
r01 | | Osnabrueck | 0 - 0 | PSV Eindhove |
| 10 Jul 21 |
r03 | | Jastrzębie | 0 - 2 | Piast Gliwic |
| 10 Jul 21 |
r03 | | Bamber Bridg | 3 - 8 | Preston |
| 10 Jul 21 |
r03 | | AFC Fylde | 0 - 1 | Blackburn |
| 10 Jul 21 |
r03 | | Caen | 0 - 0 | Ajaccio |
| 10 Jul 21 |
r03 | | Pardubice | 2 - 1 | Trencin |
| 10 Jul 21 |
r03 | | Hitchin Town | 0 - 1 | Stevenage |
| 10 Jul 21 |
r03 | | Thun | 0 - 1 | Neuchâtel X |
| 10 Jul 21 |
r03 |  | Vaduz | 0 - 0 | Zurich |
| 10 Jul 21 |
r03 | | Radcliffe | 0 - 2 | Fleetwood To |
| 10 Jul 21 |
r03 | | Havant & Wat | 2 - 5 | Portsmouth |
| 10 Jul 21 |
r03 | | St.Truiden | 2 - 1 | Westerlo |
| 10 Jul 21 |
r03 | | Bath City | 0 - 5 | Cardiff |
| 10 Jul 21 |
r03 | | Ashton | 1 - 2 | Oldham |
| 10 Jul 21 |
r03 | | Jahn Regensb | 2 - 2 | Wacker Innsb |
| 10 Jul 21 |
r03 | | Eupen | 1 - 0 | Molenbeek |
| 10 Jul 21 |
r03 | | Southport | 0 - 2 | Blackpool |
| 10 Jul 21 |
r03 | | Atherton Col | 0 - 3 | Salford City |
| 10 Jul 21 |
r05 | | FC Rodina Mo | 2 - 0 | FC Ryazan |
| 10 Jul 21 |
r05 | | Beroe | 2 - 0 | Septemvri So |
| 10 Jul 21 |
r05 | | Marek Dupnit | 2 - 1 | Sportist Svo |
| 10 Jul 21 |
r05 | | FC Rouen | 1 - 1 | Boulogne |
| 10 Jul 21 |
r03 | | MFK Ružombe | 2 - 1 | FK Pohronie |
| 10 Jul 21 |
r03 | | Tsarsko Selo | 3 - 2 | Botev Plovdi |
| 10 Jul 21 |
r03 | | Sigma Olomou | 1 - 2 | FC Midtjylla |
| 10 Jul 21 |
r03 | | LASK | 1 - 0 | FC Heidenhei |
| 10 Jul 21 |
r03 | | Atlas | 3 - 0 | Dorados |
| 10 Jul 21 |
r03 | | Troyes | 2 - 2 | Nimes |
| 10 Jul 21 |
r05 | | FC Chambly | 1 - 0 | FC Versaille |
| 10 Jul 21 |
r05 | | Radnički Sr | 2 - 1 | Inđija |
| 10 Jul 21 |
r05 | | Zvijezda 09 | 0 - 0 | Loznica |
| 10 Jul 21 |
r05 | | Skopje | 0 - 1 | Napredak Kru |
| 10 Jul 21 |
r05 | | IMT Novi Beo | 0 - 3 | Buducnost Do |
| 10 Jul 21 |
r05 | | Le Havre | 2 - 2 | Rennes |
| 10 Jul 21 |
r05 | | NK Lokomotiv | 2 - 1 | Tuzla City |
| 10 Jul 21 |
r05 | | Paris FC | 3 - 0 | Quevilly |
| 10 Jul 21 |
r05 | | Rabotnichki | 0 - 2 | Akademija Pa |
| 10 Jul 21 |
r03 | | Rennes | 2 - 2 | Le Havre |
| 10 Jul 21 |
r03 |  | Újpest FC | 1 - 1 | Diosgyor |
| 10 Jul 21 |
r03 | | Clermont Foo | 2 - 2 | Rodez AF |
| 10 Jul 21 |
r03 | | Osijek | 3 - 0 | TSC Bačka T |
| 10 Jul 21 |
r03 | | Slaven Belup | 3 - 1 | NK Aluminij |
| 10 Jul 21 |
r03 | | Olimpija Lju | 2 - 0 | FC Ashdod |
| 10 Jul 21 |
r05 | | Hrvatski Dra | 4 - 0 | Kustošija |
| 10 Jul 21 |
r03 | | Rapid Vienna | 1 - 0 | FC Copenhage |
| 10 Jul 21 |
r03 | | St Etienne | 2 - 2 | Le Puy Foot |
| 10 Jul 21 |
r05 | | CSKA Sofia | 4 - 0 | Botev Vratsa |
| 10 Jul 21 |
r05 | | OFK Petrovac | 1 - 1 | Iskra Danilo |
| 10 Jul 21 |
r05 | | Voždovac | 1 - 1 | Kolubara |
| 10 Jul 21 |
r03 | | HNK Gorica | 0 - 2 | NK Bravo |
| 10 Jul 21 |
r03 | | FC Basel | 3 - 3 | FC Aarau |
| 10 Jul 21 |
r03 | | Servette | 1 - 1 | Dynamo Kiev |
| 10 Jul 21 |
r05 | | Radnik Bijel | 1 - 1 | Mačva Šaba |
| 10 Jul 21 |
r05 | | CF America | 1 - 0 | Tigres |
| 11 Jul 21 |
r03 | | Vejle Boldkl | 1 - 0 | Lübeck |
| 11 Jul 21 |
r03 | | Estrela Amad | 1 - 1 | Benfica B |
| 11 Jul 21 |
r04 | | Mornar | 0 - 2 | Bregalnica � |
| 11 Jul 21 |
r03 | | San Diego Lo | 0 - 1 | Tijuana |
| 11 Jul 21 |
r03 | | Santos | 4 - 4 | Tampico Made |
| 11 Jul 21 |
r03 | | Skive IK | 1 - 4 | Jammerbugt |
| 11 Jul 21 |
r03 | | Lichtenberg | 1 - 3 | Cottbus |
| 11 Jul 21 |
r03 | | Monterrey | 1 - 0 | CD Guadalaja |
| 11 Jul 21 |
r04 | | Clitheroe | 0 - 1 | Chester City |
| 11 Jul 21 |
r03 | | NK Istra 196 | 1 - 1 | Koper |
| 11 Jul 21 |
r03 | | Marseille | 2 - 1 | Sète 34 |
| 11 Jul 21 |
r03 | | Paksi FC | 1 - 1 | FC Hermannst |
| 11 Jul 21 |
r03 | | FC U Craiova | 7 - 0 | Pandurii |
| 11 Jul 21 |
r03 | | Lok. Moscow | 1 - 0 | Celje |
| 11 Jul 21 |
r03 | | Spartak Mosc | 4 - 0 | PFC Sochi |
| 11 Jul 21 |
r03 | | Munich 1860 | 4 - 2 | Wacker Burgh |
| 11 Jul 21 |
r03 | | VfL Oldenbur | 1 - 6 | Oberneuland |
| 11 Jul 21 |
r03 | | Ural S.R | - | Krylya Sovet |
| 11 Jul 21 |
r03 | | Türkgücü | 0 - 0 | Karlsruhe |
| 11 Jul 21 |
r03 | | Nantwich Tow | 1 - 4 | Crewe |
| 11 Jul 21 |
r03 | | Chemie Leipz | 0 - 1 | VfV Hildeshe |
| 11 Jul 21 |
r03 | | FC Lviv | 1 - 0 | Podillya Khm |
| 11 Jul 21 |
r05 | | Rukh Lviv | 1 - 0 | Veres Rivne |
| 11 Jul 21 |
r03 | | Karlsruhe | 1 - 3 | Zenit St Pet |
| 11 Jul 21 |
r05 | | Zenit St Pet | 3 - 1 | Karlsruhe |
| 11 Jul 21 |
r05 | | Universitate | 7 - 0 | Pandurii |
| 11 Jul 21 |
r05 | | Orleans | 1 - 2 | Chateauroux |
| 11 Jul 21 |
r03 | | Arsenal Tula | 1 - 0 | Qarabag FK |
| 11 Jul 21 |
r03 | | Angers | 2 - 2 | Niort |
| 11 Jul 21 |
r03 | | Sigma Olomou | 1 - 1 | Zaglebie Lub |
| 11 Jul 21 |
r05 | | DC United | - | Alianza |
| 11 Jul 21 |
r05 | | Alajuelense | 0 - 1 | DC United |
| 12 Jul 21 |
r03 | | Viktoria Plz | 2 - 0 | FC Ufa |
| 12 Jul 21 |
r03 | | Terek Grozny | 1 - 3 | Bohemians 19 |
| 12 Jul 21 |
r03 | | Hajduk Split | 1 - 3 | Zrinjski |
| 12 Jul 21 |
r03 | | Santa Clara | 0 - 0 | Varzim |
| 12 Jul 21 |
r03 | | Austin Bold | 0 - 1 | Cruz Azul |
| 12 Jul 21 |
r03 | | FK Rostov | 1 - 2 | Lok. Moscow |
| 12 Jul 21 |
r03 | | Hamburg | 1 - 0 | Silkeborg IF |
| 12 Jul 21 |
r03 | | Sparta Pragu | 2 - 2 | Dinamo Mosco |
| 12 Jul 21 |
r03 | | Terek Grozny | 1 - 2 | Liberec |
| 12 Jul 21 |
r03 | | Apollon Lima | - | Bohemians 19 |
| 12 Jul 21 |
r03 | | Giannina | - | Gornik Leczn |
| 12 Jul 21 |
r05 | | Bohemians 19 | - | Apollon Lima |
| 12 Jul 21 |
r03 | | FC Metalist | 3 - 1 | Kryvbas Kryv |
| 12 Jul 21 |
r05 | | Hapoel Tel-A | 2 - 0 | Sektzia Nes |
| 12 Jul 21 |
r05 | | Slovacko | 1 - 0 | Nyíregyház |
| 12 Jul 21 |
r03 | | Nyíregyház | 0 - 1 | Slovacko |
| 12 Jul 21 |
r03 | | Kisvárda FC | 2 - 1 | FK Rostov |
| 12 Jul 21 |
r05 | | Maritimo | 3 - 0 | Braga B |
| 12 Jul 21 |
r05 | | Cambrian & C | 3 - 5 | Pen-y-Bont |
| 13 Jul 21 |
r03 | | Austin FC | 1 - 3 | Tigres |
| 13 Jul 21 |
r03 | | SC Cambuur | - | FC Dordrecht |
| 13 Jul 21 |
r03 | | Metalac GM | - | Pyunik Yerev |
| 13 Jul 21 |
r03 | | Estrela Amad | 0 - 0 | Braga |
| 13 Jul 21 |
r03 | | Benfica | 0 - 0 | Belenenses |
| 13 Jul 21 |
r03 | | Lille | - | Valenciennes |
| 13 Jul 21 |
r03 | | Oberneuland | 0 - 12 | Werder Breme |
| 13 Jul 21 |
r03 | | Lancaster Ci | - | Barrow |
| 13 Jul 21 |
r03 | | Heybridge Sw | - | Aldershot |
| 13 Jul 21 |
r03 | | Academico Vi | 1 - 1 | Anadia |
| 13 Jul 21 |
r03 | | Pumas | 2 - 2 | Queretaro FC |
| 13 Jul 21 |
r05 | | Dijon | 0 - 3 | Bourg-Peronn |
| 13 Jul 21 |
r03 | | Casa Pia | - | Vilafranquen |
| 13 Jul 21 |
r03 | | Arka Gdynia | 2 - 1 | Gornik Zabrz |
| 13 Jul 21 |
r03 | | Yverdon Spor | - | Young Boys |
| 13 Jul 21 |
r03 | | Fleetwood To | 1 - 0 | Port Vale |
| 13 Jul 21 |
r03 | | SC Telstar | 0 - 0 | Sparta |
| 13 Jul 21 |
r03 | | Joenkoeping | 5 - 3 | IFK Gothenbu |
| 13 Jul 21 |
r05 | | Mornar | 0 - 0 | Iskra Danilo |
| 13 Jul 21 |
r03 | | Duisburg | 2 - 3 | Preußen Mü |
| 13 Jul 21 |
r03 | | Vorskla | 0 - 0 | Mynai |
| 13 Jul 21 |
r05 | | Rudar Pljevl | 5 - 1 | Tiszakécske |
| 13 Jul 21 |
r02 | | Alanyaspor | 1 - 2 | Zorya |
| 13 Jul 21 |
r03 | | Pardubice | 0 - 2 | Vysočina Ji |
| 13 Jul 21 |
r03 | | Metz | 3 - 2 | Nancy |
| 13 Jul 21 |
r05 | | Zorya | 2 - 1 | Alanyaspor |
| 13 Jul 21 |
r05 | | Prykarpattia | 0 - 1 | Karpaty |
| 13 Jul 21 |
r03 | | Lechia Gdań | 0 - 0 | Chojniczanka |
| 13 Jul 21 |
r03 | | Club Brugge | 2 - 4 | FC Utrecht |
| 13 Jul 21 |
r03 | | Szombathelyi | 4 - 1 | Rapid Wien I |
| 13 Jul 21 |
r03 | | CSKA Moscow | 2 - 0 | ViOn Zlaté |
| 13 Jul 21 |
r03 | | Vitesse | 2 - 1 | OFI |
| 13 Jul 21 |
r03 | | Fredericia | 4 - 1 | Middelfart |
| 13 Jul 21 |
r05 | | Rumilly-Vall | - | Dijon |
| 13 Jul 21 |
r05 | | ViOn Zlaté | 0 - 2 | CSKA Moscow |
| 13 Jul 21 |
r05 | | Nyva Ternopi | 1 - 2 | Ahrobiznes |
| 13 Jul 21 |
r03 | | SC Heerenvee | 0 - 2 | Maccabi Tel |
| 13 Jul 21 |
r01 | | FC Gießen | 0 - 2 | Dortmund |
| 13 Jul 21 |
r05 | | Cartagena FC | 0 - 0 | Al-Wehda |
| 13 Jul 21 |
r05 | | Toulouse | 1 - 2 | Real Socieda |
| 13 Jul 21 |
r03 | | Covilha | 2 - 1 | Trofense |
| 13 Jul 21 |
r03 | | Young Boys | 2 - 2 | Strasbourg |
| 13 Jul 21 |
r03 | | VV Gemert | 2 - 2 | Helmond Spor |
| 13 Jul 21 |
r03 | | FC Eindhoven | 4 - 1 | VV UNA |
| 13 Jul 21 |
r04 | | VV Katwijk | 3 - 4 | Jong Volenda |
| 13 Jul 21 |
r03 | | Leyton Orien | 0 - 0 | West Ham |
| 13 Jul 21 |
r03 | | Northampton | 1 - 2 | West Ham |
| 13 Jul 21 |
r03 | | Dartford | - | Gillingham |
| 13 Jul 21 |
r03 | | Stalybridge | 0 - 2 | Oldham |
| 13 Jul 21 |
r03 | | Spennymoor T | - | Doncaster |
| 13 Jul 21 |
r03 | | Stamford AFC | 0 - 4 | Peterboro |
| 13 Jul 21 |
r05 | | Kings Lynn T | 1 - 3 | Milton Keyne |
| 13 Jul 21 |
r03 | | St Johnstone | 1 - 1 | Preston |
| 13 Jul 21 |
r01 | | Olympiakos | - | Galatasaray |
| 13 Jul 21 |
r05 | | Billericay | 0 - 3 | Colchester |
| 13 Jul 21 |
r03 | | Leamington | 3 - 1 | Walsall |
| 13 Jul 21 |
r03 | | Taunton Town | 0 - 5 | Exeter |
| 13 Jul 21 |
r03 | | Atherton Col | 0 - 4 | Bolton |
| 13 Jul 21 |
r03 | | Hungerford T | 3 - 2 | Swindon |
| 13 Jul 21 |
r03 | | Bradford Par | 0 - 5 | Bradford |
| 13 Jul 21 |
r03 | | Welling Unit | 0 - 3 | Charlton |
| 13 Jul 21 |
r04 | | Bamber Bridg | 1 - 1 | Chorley |
| 13 Jul 21 |
r05 | | Ammanford AF | 1 - 2 | Haverfordwes |
| 13 Jul 21 |
r03 | | Brighouse To | 0 - 1 | Harrogate To |
| 13 Jul 21 |
r03 | | Alfreton Tow | 0 - 1 | Sheffield We |
| 13 Jul 21 |
r04 | | Nantwich Tow | 3 - 1 | Stafford Ran |
| 13 Jul 21 |
r05 | | Tonbridge An | 1 - 0 | Lewes |
| 13 Jul 21 |
r00 | | AFC Telford | 2 - 3 | Shrewsbury |
| 13 Jul 21 |
r04 | | Skelmersdale | - | Radcliffe |
| 14 Jul 21 |
r03 | | Casa Pia | 2 - 1 | Torreense |
| 14 Jul 21 |
r03 | | TOP Oss | - | NEC Nijmegen |
| 14 Jul 21 |
r03 | | Arouca | - | F.C. Paços |
| 14 Jul 21 |
r03 | | Santa Clara | 3 - 0 | Moreirense |
| 14 Jul 21 |
r03 | | Guimaraes | - | Boavista |
| 14 Jul 21 |
r03 | | Gil Vicente | - | Chaves |
| 14 Jul 21 |
r03 | | Gent | - | Sporting CP |
| 14 Jul 21 |
r03 | | União de Le | 1 - 3 | Benfica B |
| 14 Jul 21 |
r03 | | Oud-Heverlee | - | Fortuna Sitt |
| 14 Jul 21 |
r03 | | Køge | - | Hellerup IK |
| 14 Jul 21 |
r03 | | Esbjerg | - | Weiche Flens |
| 14 Jul 21 |
r02 | | Gaziantep FK | 2 - 1 | Sumgayit FK |
| 14 Jul 21 |
r05 | | Alianza | - | Alajuelense |
| 14 Jul 21 |
r03 | | Leixoes | 2 - 1 | Torreense |
| 14 Jul 21 |
r05 | | Austin FC | 1 - 3 | Tigres |
| 14 Jul 21 |
r04 | | FC Politehni | 2 - 0 | CSM Reşiţa |
| 14 Jul 21 |
r03 | | Inter Bratis | 0 - 5 | Gyirmót |
| 14 Jul 21 |
r03 | | Jagiellonia | 1 - 1 | Aris Limasso |
| 14 Jul 21 |
r01 | | Paris SG | 4 - 0 | Le Mans |
| 14 Jul 21 |
r05 | | Gyirmót | 5 - 0 | Inter Bratis |
| 14 Jul 21 |
r03 | | Mlada Bolesl | 6 - 1 | Varnsdorf |
| 14 Jul 21 |
r03 | | Resovia Rzes | 2 - 1 | Wisla Krakow |
| 14 Jul 21 |
r03 | | Vizela | - | Boavista |
| 14 Jul 21 |
r03 | | Korona Kielc | 1 - 0 | Ruch Chorzow |
| 14 Jul 21 |
r03 | | Genk | 1 - 1 | AZ Alkmaar |
| 14 Jul 21 |
r05 | | Chaves | - | Gil Vicente |
| 14 Jul 21 |
r03 | | Rochdale | 1 - 2 | Barnsley |
| 14 Jul 21 |
r05 | | Sevan | 1 - 0 | Noravank |
| 14 Jul 21 |
r03 | | Stuttgart | 1 - 1 | Darmstadt |
| 14 Jul 21 |
r03 | | Cherno More | 1 - 0 | Sozopol |
| 14 Jul 21 |
r05 | | Paderborn | 2 - 1 | Braunschweig |
| 14 Jul 21 |
r03 | | Bochum | 6 - 0 | Bonner SC |
| 14 Jul 21 |
r03 | | Almere City | 3 - 0 | MVV Maastric |
| 14 Jul 21 |
r03 | | Inhulets | 1 - 1 | Makedonija G |
| 14 Jul 21 |
r03 | | Caen | 3 - 1 | Orleans |
| 14 Jul 21 |
r03 | | Charleroi | 2 - 2 | Molenbeek |
| 14 Jul 21 |
r03 | | Zeljeznicar | 2 - 2 | Paksi FC |
| 14 Jul 21 |
r03 | | Khimki FK | 2 - 3 | PFC Sochi |
| 14 Jul 21 |
r03 | | Levski Sofia | - | Septemvri So |
| 14 Jul 21 |
r03 | | Nantes | 1 - 0 | Guingamp |
| 14 Jul 21 |
r03 | | Stade de Rei | 1 - 0 | Paris FC |
| 14 Jul 21 |
r04 | | Inđija | 0 - 1 | Mornar |
| 14 Jul 21 |
r04 | | Gyor | 0 - 3 | Vasas |
| 14 Jul 21 |
r04 | | Etar Veliko | 1 - 0 | Spartak Varn |
| 14 Jul 21 |
r05 | | Lille | 0 - 1 | Gent |
| 14 Jul 21 |
r05 | | Makedonija G | 1 - 1 | Inhulets |
| 14 Jul 21 |
r01 | | Trabzonspor | 5 - 3 | Ümraniyespo |
| 14 Jul 21 |
r03 | | Lokomotiv So | 0 - 1 | Botev Vratsa |
| 14 Jul 21 |
r04 | | Skopje | 2 - 0 | Akademija Pa |
| 14 Jul 21 |
r04 | | Grafičar | 2 - 2 | Bregalnica � |
| 14 Jul 21 |
r03 | | Hertha | 4 - 4 | Hannover |
| 14 Jul 21 |
r03 | | Wuerzburger | 1 - 0 | SPVGG Greuth |
| 14 Jul 21 |
r03 | | FC Krasnodar | 2 - 2 | Dynamo Česk |
| 14 Jul 21 |
r05 | | CSA Steaua B | 3 - 1 | Astra |
| 14 Jul 21 |
r03 | | Cherno More | 3 - 0 | Dobrudzha |
| 14 Jul 21 |
r03 | | Viktoria Ber | 2 - 5 | Union Berlin |
| 14 Jul 21 |
r03 | | Beerschot VA | 1 - 2 | FC Utrecht |
| 14 Jul 21 |
r03 | | GKS Katowice | 2 - 1 | Bełchatów |
| 14 Jul 21 |
r03 | | Montpellier | 1 - 0 | Rodez AF |
| 14 Jul 21 |
r03 | | Kispest Honv | 3 - 5 | Pribram |
| 14 Jul 21 |
r03 | | SD Amorebiet | 1 - 1 | Burgos |
| 14 Jul 21 |
r04 | | Diosgyor | 2 - 0 | Kosice |
| 14 Jul 21 |
r05 | | Benfica B | 3 - 1 | União de Le |
| 14 Jul 21 |
r05 | | Orleans | 1 - 3 | Caen |
| 14 Jul 21 |
r05 | | NK Varaždin | 4 - 0 | Dubrava |
| 14 Jul 21 |
r03 | | St. Gilloise | 1 - 1 | Valenciennes |
| 14 Jul 21 |
r05 | | Akademija Pa | 0 - 2 | Skopje |
| 14 Jul 21 |
r03 | | Angers | - | US Avranches |
| 14 Jul 21 |
r03 | | Clermont Foo | 0 - 0 | Grenoble |
| 14 Jul 21 |
r03 | | Leverkusen | - | Wehen Wiesba |
| 14 Jul 21 |
r03 | | Skive IK | 1 - 0 | Holstebro |
| 14 Jul 21 |
r03 | | FC Sion | - | Dynamo Kiev |
| 14 Jul 21 |
r03 | | Ajaccio | - | GFCO Ajaccio |
| 14 Jul 21 |
r03 | | KMSK Deinze | 1 - 3 | Waregem |
| 14 Jul 21 |
r03 | | Alaves | 1 - 3 | SD Logroñé |
| 14 Jul 21 |
r03 | | Atletico de | 1 - 0 | Correcaminos |
| 14 Jul 21 |
r03 | | Thisted | - | Jammerbugt |
| 14 Jul 21 |
r04 | | NK Inter Zap | 2 - 0 | Sesvete |
| 14 Jul 21 |
r05 | | Cibalia | 0 - 2 | BSK Bijelo B |
| 14 Jul 21 |
r05 | | Orijent 1919 | 1 - 1 | Opatija |
| 14 Jul 21 |
r05 | | Quevilly | 0 - 1 | Red Star |
| 14 Jul 21 |
r05 | | Uta Arad | 3 - 2 | Ripensia Tim |
| 14 Jul 21 |
r05 | | Eintracht Tr | - | Rot-Weiß Ko |
| 14 Jul 21 |
r03 | | Blauw Geel 3 | 1 - 1 | FC Den Bosch |
| 14 Jul 21 |
r03 | | FK Rubin Kaz | 0 - 4 | Spartak Mosc |
| 14 Jul 21 |
r03 | | St Albans Ci | 0 - 1 | Stevenage |
| 14 Jul 21 |
r03 | | Bristol City | 0 - 0 | Celtic |
| 14 Jul 21 |
r05 | | Tamworth | 3 - 1 | West Brom |
| 14 Jul 21 |
r03 | | Ashton | 1 - 5 | Crewe |
| 14 Jul 21 |
r03 | | Witton | 0 - 6 | Crewe |
| 14 Jul 21 |
r05 | | Sporting CP | 2 - 2 | Portimonense |
| 14 Jul 21 |
r03 | | Morelia | 3 - 0 | CS Herediano |
| 15 Jul 21 |
r03 | | Lask Juniors | - | Slavia Pragu |
| 15 Jul 21 |
r05 | | Zlatibor Ča | 0 - 1 | Iskra Danilo |
| 15 Jul 21 |
r05 | | DC United | 1 - 0 | Alianza |
| 15 Jul 21 |
r03 | | FC Lviv | 1 - 2 | FC Kolos Kov |
| 15 Jul 21 |
r03 | | Maritimo | 4 - 0 | Varzim |
| 15 Jul 21 |
r03 | | F.C. Paços | - | Santa Clara |
| 15 Jul 21 |
r03 | | Tijuana | 0 - 0 | Mazatlán |
| 15 Jul 21 |
r03 | | Atlas | 1 - 0 | Tampico Made |
| 15 Jul 21 |
r03 | | Covilha | 1 - 0 | Academico Vi |
| 15 Jul 21 |
r03 | | Dinamo Mosco | 0 - 2 | Jablonec |
| 15 Jul 21 |
r03 | | SC Heracles | 2 - 1 | Rödinghause |
| 15 Jul 21 |
r05 | | Santa Clara | - | F.C. Paços |
| 15 Jul 21 |
r03 | | Viktoria Plz | 1 - 0 | Arsenal Tula |
| 15 Jul 21 |
r02 | | Antalyaspor | 0 - 1 | Kocaelispor |
| 15 Jul 21 |
r05 | | Zaglebie Lub | 0 - 1 | Warta Pozna� |
| 15 Jul 21 |
r02 | | Fenerbahce | 2 - 0 | Csikszereda |
| 15 Jul 21 |
r03 | | Warta Pozna� | 1 - 0 | Zaglebie Lub |
| 15 Jul 21 |
r03 | | AEL Limassol | 2 - 2 | Olympiakos N |
| 15 Jul 21 |
r03 | | Slovacko | 2 - 1 | Paksi FC |
| 15 Jul 21 |
r05 | | Atlético Pe | 2 - 0 | Interclube |
| 15 Jul 21 |
r05 | | Dynamo Kiev | 3 - 0 | Thonon Évia |
| 15 Jul 21 |
r05 | | Hapoel Nof H | 0 - 2 | Hapoel Tel-A |
| 15 Jul 21 |
r05 | | Paksi FC | 1 - 2 | Slovacko |
| 15 Jul 21 |
r03 | | DAC 1904 Dun | 2 - 1 | Újpest FC |
| 15 Jul 21 |
r03 | | AEK Larnaca | 1 - 0 | Doxa Katokop |
| 15 Jul 21 |
r03 | | Dinamo Mosco | 0 - 2 | MTK Hungaria |
| 15 Jul 21 |
r03 | | Apoel Nicosi | 1 - 0 | PAEEK |
| 15 Jul 21 |
r02 | | Kasimpasa | 3 - 1 | Istanbulspor |
| 15 Jul 21 |
r03 | | Qarabag FK | 2 - 2 | Augsburg |
| 15 Jul 21 |
r03 | | Kisvárda FC | 3 - 2 | Maccabi Peta |
| 15 Jul 21 |
r03 | | Beroe | 0 - 2 | Arda Kardzha |
| 15 Jul 21 |
r05 | | Arda Kardzha | 2 - 0 | Beroe |
| 15 Jul 21 |
r03 | | Straelen | 2 - 2 | VVV-Venlo |
| 15 Jul 21 |
r03 | | AEK | 3 - 0 | Apollon Lima |
| 15 Jul 21 |
r05 | | Sporting CP | 2 - 1 | Belenenses |
| 16 Jul 21 |
r03 | | Benfica | - | Gent |
| 16 Jul 21 |
r03 | | Freiburg | - | Vaduz |
| 16 Jul 21 |
r03 | | FK Rostov | - | Burnley |
| 16 Jul 21 |
r05 | | FC Volendam | 2 - 1 | SC Heracles |
| 16 Jul 21 |
r05 | | Lechia Gdań | 3 - 2 | FK Panevėž |
| 16 Jul 21 |
r05 | | Ħamrun Spar | 0 - 0 | Santa Lucia |
| 16 Jul 21 |
r05 | | Colne | 1 - 0 | Hyde United |
| 16 Jul 21 |
r05 | | Bishops Stor | 2 - 2 | Maldon & Tip |
| 16 Jul 21 |
r03 | | Bournemouth | 4 - 2 | Linense |
| 16 Jul 21 |
r03 | | Armagh City | 1 - 6 | Coleraine |
| 16 Jul 21 |
r03 | | Pachuca | 1 - 3 | CD Guadalaja |
| 16 Jul 21 |
r05 | | Sektzia Nes | 3 - 1 | Hapoel Ramat |
| 16 Jul 21 |
r05 | | Maccabi Neta | 0 - 2 | Kafr Qasim |
| 16 Jul 21 |
r03 | | Getafe | 1 - 0 | UD Ibiza |
| 16 Jul 21 |
r03 | | FC Lausanne- | 4 - 0 | Stade Lausan |
| 16 Jul 21 |
r05 | | Cracovia Kra | 0 - 4 | Nieciecza |
| 16 Jul 21 |
r03 | | Nieciecza | 4 - 0 | Cracovia Kra |
| 16 Jul 21 |
r03 | | Gil Vicente | - | Famalicao |
| 16 Jul 21 |
r03 | | Anderlecht | 1 - 1 | OFI |
| 16 Jul 21 |
r03 | | Køge | 2 - 2 | FC Helsingoe |
| 16 Jul 21 |
r03 | | Jahn Regensb | 1 - 0 | Liberec |
| 16 Jul 21 |
r03 | | Sigma Olomou | 1 - 1 | Arka Gdynia |
| 16 Jul 21 |
r05 | | FK Senica | 0 - 5 | Bohemians 19 |
| 16 Jul 21 |
r03 | | Bohemians 19 | 5 - 0 | FK Senica |
| 16 Jul 21 |
r03 | | Teplice | 1 - 2 | Dukla Praha |
| 16 Jul 21 |
r03 | | Aberdeen | - | Reading |
| 16 Jul 21 |
r05 | | Vaduz | 1 - 1 | Freiburg |
| 16 Jul 21 |
r03 | | Pafos FC | 1 - 0 | Dynamo Česk |
| 16 Jul 21 |
r03 | | Slavia Pragu | 1 - 1 | Piast Gliwic |
| 16 Jul 21 |
r03 | | Dynamo Česk | 0 - 1 | Pafos FC |
| 16 Jul 21 |
r03 | | Augsburg | - | Ingolstadt |
| 16 Jul 21 |
r05 | | Podillya Khm | 3 - 2 | FC Kolos Kov |
| 16 Jul 21 |
r03 | | Triglav Kran | 1 - 1 | MTK Hungaria |
| 16 Jul 21 |
r03 | | FK Rostov | 1 - 0 | Beitar Jerus |
| 16 Jul 21 |
r02 | | Gaziantep FK | 0 - 0 | Adanaspor |
| 16 Jul 21 |
r05 | | Nimes | - | Sète 34 |
| 16 Jul 21 |
r05 | | Stade Brioch | 1 - 1 | FC Versaille |
| 16 Jul 21 |
r03 | | Cherno More | 3 - 0 | Neftochimic |
| 16 Jul 21 |
r05 | | Laval | 1 - 2 | SO Cholet |
| 16 Jul 21 |
r03 | | St Etienne | 1 - 1 | Bourg-Peronn |
| 16 Jul 21 |
r03 | | Germania Hal | 3 - 1 | Rot-Weiß Er |
| 16 Jul 21 |
r05 | | FC Groningen | 2 - 3 | SC Verl |
| 16 Jul 21 |
r05 | | US Avranches | 2 - 5 | Concarneau |
| 16 Jul 21 |
r05 | | Krka | 0 - 2 | Budafoki MTE |
| 16 Jul 21 |
r03 | | SC Verl | 3 - 2 | FC Groningen |
| 16 Jul 21 |
r03 | | Yverdon Spor | 1 - 3 | Sochaux |
| 16 Jul 21 |
r03 | | Lokomotiv Pl | 1 - 0 | Hebar Pazard |
| 16 Jul 21 |
r05 | | FC Villefran | 1 - 0 | Le Puy Foot |
| 16 Jul 21 |
r03 | | Beroe | 6 - 0 | Sozopol |
| 16 Jul 21 |
r03 | | Bastia | 1 - 0 | Nice |
| 16 Jul 21 |
r03 |  | MVV Maastric | - | Helmond Spor |
| 16 Jul 21 |
r03 | | Helmond Spor | - | FC Dordrecht |
| 16 Jul 21 |
r03 | | Bordeaux | 1 - 1 | Niort |
| 16 Jul 21 |
r03 | | Lokomotive L | 2 - 0 | VfV Hildeshe |
| 16 Jul 21 |
r05 | | Nice | 0 - 1 | Bastia |
| 16 Jul 21 |
r03 | | Drochtersen- | 0 - 1 | Oberneuland |
| 16 Jul 21 |
r03 | | SV TEC | 3 - 0 | Jong Utrecht |
| 16 Jul 21 |
r03 | | Aberdeen | 0 - 0 | St Johnstone |
| 16 Jul 21 |
r03 | | Gillingham | - | QPR |
| 16 Jul 21 |
r03 | | Raith Rvs | 1 - 3 | Hibernian |
| 16 Jul 21 |
r03 | | SC Farense | 0 - 0 | Braga |
| 16 Jul 21 |
r05 | | Bath City | 3 - 4 | Exeter |
| 16 Jul 21 |
r03 | | Oxford City | 2 - 3 | Oxford Utd |
| 16 Jul 21 |
r03 | | Kings Lynn T | 1 - 3 | Norwich |
| 16 Jul 21 |
r03 | | Matlock | 1 - 0 | Mansfield |
| 16 Jul 21 |
r03 | | Woking | 0 - 1 | West Brom |
| 17 Jul 21 |
r03 | | Wisla Plock | - | Lechia Gdań |
| 17 Jul 21 |
r04 | | Dorchester T | 5 - 0 | Christchurch |
| 17 Jul 21 |
r03 | | Amsterdamsch | - | SC Telstar |
| 17 Jul 21 |
r03 | | Apollon Lima | - | Doxa Katokop |
| 17 Jul 21 |
r03 | | Volyn | - | FC Lviv |
| 17 Jul 21 |
r03 | | CD Teruel | - | Zaragoza |
| 17 Jul 21 |
r03 | | Guimaraes | - | Gil Vicente |
| 17 Jul 21 |
r03 | | Arouca | - | Chaves |
| 17 Jul 21 |
r03 | | Casa Pia | - | Benfica B |
| 17 Jul 21 |
r03 | | Toluca | - | Atlante |
| 17 Jul 21 |
r03 | | Nurnberg | - | Beerschot VA |
| 17 Jul 21 |
r04 | | Javor Ivanji | 1 - 0 | Mačva Šaba |
| 17 Jul 21 |
r04 | | NK Varaždin | 3 - 2 | NK Inter Zap |
| 17 Jul 21 |
r04 | | Radnički Sr | 0 - 2 | Al-Faisaly |
| 17 Jul 21 |
r05 | | Pécs | 1 - 0 | Siófok |
| 17 Jul 21 |
r05 | | Burgos | 0 - 0 | Lugo |
| 17 Jul 21 |
r03 | | FC Porto | 3 - 2 | Academico Vi |
| 17 Jul 21 |
r05 | | Dergview | 0 - 1 | Ballinamalla |
| 17 Jul 21 |
r05 | | TSV Steinbac | 1 - 1 | Schalke 04 I |
| 17 Jul 21 |
r05 | | Hessen Kasse | 4 - 0 | Wuppertaler |
| 17 Jul 21 |
r05 | | Litex Lovech | 0 - 1 | Minyor Perni |
| 17 Jul 21 |
r05 | | Swindon Supe | 0 - 2 | Gloucester C |
| 17 Jul 21 |
r05 | | Dorking Wand | 4 - 0 | Leatherhead |
| 17 Jul 21 |
r05 | | Haringey Bor | 0 - 0 | Billericay |
| 17 Jul 21 |
r05 | | Szolnok | 1 - 1 | Kosice |
| 17 Jul 21 |
r05 | | Hednesford T | 1 - 0 | Stafford Ran |
| 17 Jul 21 |
r05 | | Calahorra | 2 - 1 | Eibar |
| 17 Jul 21 |
r03 | | Excelsior Ma | 2 - 1 | SC Telstar |
| 17 Jul 21 |
r05 | | Ingolstadt | 1 - 1 | SPVGG Greuth |
| 17 Jul 21 |
r05 | | Næstved BK | 2 - 3 | Hillerød |
| 17 Jul 21 |
r05 | | KV Oostende | 0 - 0 | Mouscron-Per |
| 17 Jul 21 |
r05 | | Hamburg | 1 - 0 | FC Basel |
| 17 Jul 21 |
r05 | | Iskra Danilo | 1 - 2 | Bregalnica � |
| 17 Jul 21 |
r05 | | Kings Langle | 1 - 2 | St Albans Ci |
| 17 Jul 21 |
r05 | | Mafra | 2 - 0 | Vilafranquen |
| 17 Jul 21 |
r01 | | Milan | 6 - 0 | Pro Sesto |
| 17 Jul 21 |
r03 | | Slaven Belup | 2 - 2 | Sesvete |
| 17 Jul 21 |
r03 | | Teplice | - | Dukla Praha |
| 17 Jul 21 |
r03 | | Frem | - | AB Gladsaxe |
| 17 Jul 21 |
r03 | | De Graafscha | 4 - 0 | FC Dordrecht |
| 17 Jul 21 |
r03 | | Linfield | 0 - 6 | Stoke |
| 17 Jul 21 |
r03 | | Blackpool | 1 - 3 | Accrington |
| 17 Jul 21 |
r03 | | Hearts | 0 - 2 | Sunderland |
| 17 Jul 21 |
r03 | | FC Lviv | 1 - 0 | Nyva Ternopi |
| 17 Jul 21 |
r03 | | Lokomotiv So | 3 - 1 | Levski Lom |
| 17 Jul 21 |
r03 | | SSV Ulm | 2 - 1 | Stuttgarter |
| 17 Jul 21 |
r03 | | Strasbourg | 0 - 1 | FC Sion |
| 17 Jul 21 |
r04 | | SCM Gloria B | 1 - 0 | Petrolul |
| 17 Jul 21 |
r04 | | Deveronvale | 4 - 5 | Rothes |
| 17 Jul 21 |
r04 | | Spartak Varn | 0 - 4 | Dunav Ruse |
| 17 Jul 21 |
r04 | | Sirens FC | - | Gudja United |
| 17 Jul 21 |
r05 | | Alcorcon | 1 - 2 | Fuenlabrada |
| 17 Jul 21 |
r05 | | Chelsea | 6 - 1 | Peterboro |
| 17 Jul 21 |
r03 | | Tsarsko Selo | 0 - 0 | Pirin Blagoe |
| 17 Jul 21 |
r03 | | ViOn Zlaté | 2 - 1 | ŠKF Sereď |
| 17 Jul 21 |
r03 | | Zaglebie Sos | 2 - 2 | GKS Katowice |
| 17 Jul 21 |
r03 | | Portimonense | 1 - 1 | Braga |
| 17 Jul 21 |
r03 | | Fuenlabrada | 2 - 1 | Alcorcon |
| 17 Jul 21 |
r03 | | Sepsi OSK Sf | 2 - 0 | Politehnica |
| 17 Jul 21 |
r03 | | Jastrzębie | 2 - 0 | Odra Opole |
| 17 Jul 21 |
r05 | | Mezőkövesd | - | Diosgyor |
| 17 Jul 21 |
r03 | | Táborsko | - | Viktoria Plz |
| 17 Jul 21 |
r03 | | Gyirmót | 2 - 1 | Ajka |
| 17 Jul 21 |
r05 | | Covilha | 1 - 1 | Portimonense |
| 17 Jul 21 |
r03 | | Tychy 71 | 1 - 1 | SFC Opava |
| 17 Jul 21 |
r05 | | Kispest Honv | 1 - 0 | FK Rostov |
| 17 Jul 21 |
r03 | | FK Rostov | 0 - 1 | Kispest Honv |
| 17 Jul 21 |
r03 | | Leixoes | 4 - 1 | Caldas |
| 17 Jul 21 |
r03 | | Líšeň | - | Banik Ostrav |
| 17 Jul 21 |
r03 | | Kolding IF | 4 - 1 | VSK Århus |
| 17 Jul 21 |
r03 | | Puszcza Niep | 2 - 4 | Sandecja Now |
| 17 Jul 21 |
r05 | | Sandecja Now | 4 - 2 | Puszcza Niep |
| 17 Jul 21 |
r01 | | Paris SG | 2 - 2 | FC Chambly |
| 17 Jul 21 |
r05 | | Vasas | 3 - 2 | Kazincbarcik |
| 17 Jul 21 |
r03 | | Vizela | 0 - 0 | Estoril-Prai |
| 17 Jul 21 |
r05 | | Bełchatów | 1 - 1 | Polonia Wars |
| 17 Jul 21 |
r03 | | Esbjerg | 1 - 2 | Aarhus Frema |
| 17 Jul 21 |
r03 | | Chojniczanka | 3 - 1 | Chrobry Gło |
| 17 Jul 21 |
r05 | | São João d | - | União de Le |
| 17 Jul 21 |
r05 | | AC Horsens | 2 - 0 | Fredericia |
| 17 Jul 21 |
r03 | | Fredericia | 0 - 2 | AC Horsens |
| 17 Jul 21 |
r03 | | Watford | 2 - 1 | Colchester |
| 17 Jul 21 |
r03 | | Jagiellonia | 4 - 0 | Gornik Leczn |
| 17 Jul 21 |
r05 | | Korona Kielc | 2 - 2 | LKS Lodz |
| 17 Jul 21 |
r05 | | Charleroi | 0 - 2 | PAOK |
| 17 Jul 21 |
r03 | | Nurnberg | 3 - 2 | Munich 1860 |
| 17 Jul 21 |
r03 | | Stamford AFC | 2 - 1 | Northampton |
| 17 Jul 21 |
r03 | | Lyngby | 2 - 0 | Fremad Amage |
| 17 Jul 21 |
r03 | | Barnsley | 2 - 0 | Sheffield We |
| 17 Jul 21 |
r03 | | Molenbeek | 0 - 1 | SC Cambuur |
| 17 Jul 21 |
r03 | | HOBRO | 3 - 0 | Jammerbugt |
| 17 Jul 21 |
r03 | | Wycombe | 1 - 0 | Stevenage |
| 17 Jul 21 |
r03 | | TSV Havelse | 1 - 1 | Cottbus |
| 17 Jul 21 |
r03 | | VSG Altglien | 3 - 3 | Hertha II |
| 17 Jul 21 |
r03 | | FC Heidenhei | 1 - 0 | Hoffenheim |
| 17 Jul 21 |
r03 | | SC Heerenvee | 3 - 2 | TOP Oss |
| 17 Jul 21 |
r03 | | Blackpool | 1 - 3 | Newport |
| 17 Jul 21 |
r03 | | Quick Boys | 2 - 0 | Jong PSV |
| 17 Jul 21 |
r03 | | Bristol Rove | 1 - 1 | Plymouth |
| 17 Jul 21 |
r03 | | Jong Ajax | 1 - 4 | FC Emmen |
| 17 Jul 21 |
r03 | | Cardiff | - | Cambridge Un |
| 17 Jul 21 |
r03 | | Kaiserslaute | 2 - 0 | Stuttgart II |
| 17 Jul 21 |
r03 | | Waldhof Mann | 5 - 3 | FC Gießen |
| 17 Jul 21 |
r03 | | Hansa Rostoc | 1 - 2 | Braunschweig |
| 17 Jul 21 |
r03 | | Skive IK | 2 - 0 | Middelfart |
| 17 Jul 21 |
r03 | | Lucerne | 2 - 0 | FC Wil |
| 17 Jul 21 |
r03 | | Walsall | 0 - 1 | Crystal Pala |
| 17 Jul 21 |
r05 | | Viktoria Ber | 1 - 1 | Chemnitzer F |
| 17 Jul 21 |
r03 | | Lech Poznan | - | Miedz Legnic |
| 17 Jul 21 |
r05 | | Hannoversche | 1 - 2 | St Pauli II |
| 17 Jul 21 |
r03 | | Optik Rathen | 2 - 2 | Greifswalder |
| 17 Jul 21 |
r03 | | Chemnitzer F | 1 - 1 | Viktoria Ber |
| 17 Jul 21 |
r03 | | FC Emmen | - | Jong Utrecht |
| 17 Jul 21 |
r03 | | Yate Town | 0 - 2 | Forest Green |
| 17 Jul 21 |
r03 | | Karlsruhe | 1 - 0 | FC Saarbrüc |
| 17 Jul 21 |
r03 | | Wehen Wiesba | 1 - 2 | Elversberg |
| 17 Jul 21 |
r03 | | Hallescher F | 2 - 2 | Holstein Kie |
| 17 Jul 21 |
r03 |  | De Graafscha | - | FC Eindhoven |
| 17 Jul 21 |
r03 | | Hannover II | 0 - 3 | Fortuna Düs |
| 17 Jul 21 |
r03 | | Spennymoor T | - | Barrow |
| 17 Jul 21 |
r03 | | FC Eilenburg | 3 - 0 | Bischofswerd |
| 17 Jul 21 |
r03 | | Wuerzburger | 1 - 2 | Carl Zeiss J |
| 17 Jul 21 |
r03 | | Zwickau | 1 - 1 | Ústí nad L |
| 17 Jul 21 |
r03 | | FC Dordrecht | - | Excelsior |
| 17 Jul 21 |
r03 | | Mechelen | 2 - 1 | NFC Volos |
| 17 Jul 21 |
r03 | | Waregem | 0 - 0 | FC Utrecht |
| 17 Jul 21 |
r03 | | NAC Breda | 2 - 1 | FC Den Bosch |
| 17 Jul 21 |
r03 | | Willem II | 2 - 0 | Excelsior |
| 17 Jul 21 |
r03 | | Hannover | 2 - 4 | Magdeburg |
| 17 Jul 21 |
r03 | | Caen | 1 - 0 | Nantes |
| 17 Jul 21 |
r03 | | St.Truiden | 1 - 1 | Eupen |
| 17 Jul 21 |
r03 | | Zurich | 6 - 1 | SC Kriens |
| 17 Jul 21 |
r03 | | FK Rubin Kaz | 1 - 3 | PFC Sochi |
| 17 Jul 21 |
r03 | | FC Olexandri | 2 - 2 | Kryvbas Kryv |
| 17 Jul 21 |
r03 | | Paderborn | 3 - 1 | Mönchenglad |
| 17 Jul 21 |
r03 | | Osnabrueck | 0 - 1 | FC Groningen |
| 17 Jul 21 |
r03 | | Grasshoppers | 2 - 3 | Thun |
| 17 Jul 21 |
r02 | | Kayserispor | 0 - 1 | Samsunspor |
| 17 Jul 21 |
r05 | | Nantes | 0 - 1 | Caen |
| 17 Jul 21 |
r05 | | Ebbsfleet Un | - | Gillingham |
| 17 Jul 21 |
r05 | | Duisburg | - | Dortmund |
| 17 Jul 21 |
r05 | | Dortmund | 1 - 3 | Bochum |
| 17 Jul 21 |
r01 | | Rangers | 2 - 2 | Arsenal |
| 17 Jul 21 |
r03 | | Lens | 2 - 2 | Le Havre |
| 17 Jul 21 |
r03 | | Fortuna Düs | 3 - 0 | Oud-Heverlee |
| 17 Jul 21 |
r03 | | Jahn Regensb | 1 - 0 | Türkgücü |
| 17 Jul 21 |
r00 | | AFC Telford | 2 - 2 | Birmingham |
| 17 Jul 21 |
r03 | | Chorley | 1 - 0 | Morecambe |
| 17 Jul 21 |
r03 | | Elgin City | 3 - 0 | Nairn County |
| 17 Jul 21 |
r03 | | Boston Unite | 5 - 0 | Lincoln |
| 17 Jul 21 |
r03 | | Horsham | 0 - 5 | Crawley |
| 17 Jul 21 |
r03 | | Tamworth | - | Shrewsbury |
| 17 Jul 21 |
r03 | | St. Gallen | 2 - 1 | Ath Bilbao |
| 17 Jul 21 |
r03 | | Farnborough | 5 - 7 | Aldershot |
| 17 Jul 21 |
r03 | | SC Dnipro-1 | 2 - 0 | Alians Lypov |
| 17 Jul 21 |
r03 | | Fortuna Sitt | 1 - 1 | Beerschot VA |
| 17 Jul 21 |
r03 | | Port Vale | 0 - 2 | Nottingham F |
| 17 Jul 21 |
r03 | | AFC Wimbledo | 0 - 1 | Brentford |
| 17 Jul 21 |
r03 | | Ein Frankfur | 1 - 0 | Sandhausen |
| 17 Jul 21 |
r03 | | Almere City | 3 - 3 | SV Meppen |
| 17 Jul 21 |
r03 | | Braintree To | 3 - 4 | Dagenham & R |
| 17 Jul 21 |
r03 | | Amiens | 3 - 4 | St. Gilloise |
| 17 Jul 21 |
r01 | | Leyton Orien | 1 - 1 | Tottenham |
| 17 Jul 21 |
r03 | | Casa Pia | 1 - 0 | Mafra |
| 17 Jul 21 |
r03 | | Tijuana | 3 - 0 | CS Herediano |
| 17 Jul 21 |
r05 | | Beerschot VA | 1 - 1 | Fortuna Sitt |
| 17 Jul 21 |
r05 | | Havant & Wat | 2 - 3 | Bognor Regis |
| 17 Jul 21 |
r05 | | Nancy | 2 - 2 | Guingamp |
| 17 Jul 21 |
r05 | | FC Rouen | 1 - 2 | Olympique Sa |
| 17 Jul 21 |
r03 | | Southport | 0 - 2 | Huddersfield |
| 17 Jul 21 |
r03 | | Cheltenham | 0 - 3 | Birmingham |
| 17 Jul 21 |
r03 | | RasenBallspo | 1 - 0 | AZ Alkmaar |
| 17 Jul 21 |
r03 | | Dartford | 1 - 2 | Charlton |
| 17 Jul 21 |
r03 | | FC United of | 1 - 1 | Bolton |
| 17 Jul 21 |
r03 | | Maidstone | - | Sutton Unite |
| 17 Jul 21 |
r05 | | Buxton F.C. | - | Barwell FC |
| 17 Jul 21 |
r03 | | Boreham Wood | 1 - 3 | Luton |
| 17 Jul 21 |
r05 | | Paris FC | 2 - 2 | Creteil |
| 17 Jul 21 |
r03 | | Alfreton Tow | 3 - 2 | Chesterfield |
| 17 Jul 21 |
r03 | | Swindon | - | Swansea |
| 17 Jul 21 |
r05 | | AFC Sudbury | 1 - 2 | Brightlingse |
| 17 Jul 21 |
r03 | | Oldham | 1 - 2 | Wigan |
| 17 Jul 21 |
r03 | | Farsley Celt | - | Scunthorpe |
| 17 Jul 21 |
r03 | | Rochdale | 3 - 3 | Fleetwood To |
| 17 Jul 21 |
r03 | | Mlada Bolesl | 4 - 1 | Viktoria Ži |
| 17 Jul 21 |
r03 | | Lommel SK | 1 - 1 | Roda JC |
| 17 Jul 21 |
r03 | | Bradford | 2 - 0 | Doncaster |
| 17 Jul 21 |
r03 | | Crewe | 1 - 0 | Wolves |
| 17 Jul 21 |
r03 |  | Zlín | 1 - 1 | Zbrojovka Br |
| 17 Jul 21 |
r03 | | Lorient | 3 - 2 | Brest |
| 17 Jul 21 |
r03 | | Hradec Král | 2 - 0 | Chrudim |
| 17 Jul 21 |
r03 | | Auxerre | 1 - 3 | Orleans |
| 17 Jul 21 |
r03 | | Aris Limasso | 0 - 1 | Wisla Plock |
| 17 Jul 21 |
r03 | | Gornik Zabrz | 1 - 3 | Banik Ostrav |
| 17 Jul 21 |
r03 | | Standard | 3 - 3 | Rennes |
| 17 Jul 21 |
r03 | | Botev Vratsa | 1 - 1 | Apollon Smir |
| 17 Jul 21 |
r03 | | Atlas | 1 - 1 | Atletico de |
| 17 Jul 21 |
r03 | | Zurich | 1 - 4 | Neuchâtel X |
| 17 Jul 21 |
r05 | | Annecy | 2 - 1 | Toulon |
| 17 Jul 21 |
r03 | | Kortrijk | 1 - 1 | Lille |
| 17 Jul 21 |
r03 | | Dinamo Mosco | 3 - 0 | Budafoki MTE |
| 17 Jul 21 |
r03 | | MFK Ružombe | 2 - 1 | Karvina |
| 17 Jul 21 |
r05 | | Angers | 3 - 0 | Chateauroux |
| 17 Jul 21 |
r03 | | Dijon | 1 - 2 | Troyes |
| 17 Jul 21 |
r03 | | Chateauroux | 0 - 3 | Angers |
| 17 Jul 21 |
r03 | | NEC Nijmegen | 3 - 0 | RKC Waalwijk |
| 17 Jul 21 |
r03 | | Pardubice | 2 - 0 | Vlašim |
| 17 Jul 21 |
r03 | | Antwerp | 0 - 0 | Monaco |
| 17 Jul 21 |
r03 | | Metz | 1 - 1 | RFC Seraing |
| 17 Jul 21 |
r03 | | LKS Lodz | - | Korona Kielc |
| 17 Jul 21 |
r03 | | Levski Sofia | 2 - 0 | Etar Veliko |
| 17 Jul 21 |
r03 | | Nimes | 1 - 0 | Ajaccio |
| 17 Jul 21 |
r03 | | Toulouse | 2 - 0 | Rodez AF |
| 17 Jul 21 |
r03 | | Clermont Foo | 3 - 2 | Montpellier |
| 17 Jul 21 |
r03 | | Alaves | 5 - 2 | SD Amorebiet |
| 17 Jul 21 |
r03 | | Strasbourg | - | Cercle Brugg |
| 17 Jul 21 |
r03 | | Kispest Honv | - | Al-Ettifaq |
| 17 Jul 21 |
r03 | | Slavia Sofia | 4 - 0 | Montana |
| 17 Jul 21 |
r05 | | USL Dunkerqu | 1 - 0 | Boulogne |
| 17 Jul 21 |
r05 | | Makedonija G | 1 - 2 | CSKA 1948 |
| 17 Jul 21 |
r05 | | Gyor | 2 - 2 | Al Hazm |
| 17 Jul 21 |
r03 | | Valenciennes | 0 - 1 | Stade de Rei |
| 17 Jul 21 |
r03 | | Lyon | 2 - 0 | FC Villefran |
| 17 Jul 21 |
r03 | | St Etienne | 2 - 1 | Grenoble |
| 17 Jul 21 |
r02 | | Alanyaspor | 0 - 1 | Polissya Zhy |
| 17 Jul 21 |
r05 | | Cartagena FC | 2 - 0 | Al-Raed |
| 17 Jul 21 |
r05 | | Pau FC | 0 - 0 | Canet Roussi |
| 17 Jul 21 |
r05 | | Sociedad | 6 - 1 | Huesca |
| 17 Jul 21 |
r05 | | Quevilly | 0 - 1 | Le Mans |
| 17 Jul 21 |
r03 | | Ethnikos Ach | 0 - 2 | Anorthosis F |
| 17 Jul 21 |
r03 | | Nice | 2 - 1 | Dynamo Kiev |
| 17 Jul 21 |
r03 | | Wisla Krakow | 1 - 1 | Podbeskidzie |
| 17 Jul 21 |
r03 | | Cristo Atlé | - | Valladolid |
| 17 Jul 21 |
r01 | | Lugano | 2 - 2 | Inter |
| 17 Jul 21 |
r03 | | Atlético Sa | 1 - 0 | Cadiz |
| 17 Jul 21 |
r03 | | Necaxa | 2 - 0 | Queretaro FC |
| 18 Jul 21 |
r03 | | Santos | - | Tepatitlán |
| 18 Jul 21 |
r03 | | Moreirense | - | Academico Vi |
| 18 Jul 21 |
r03 | | Leverkusen | - | Dinamo Mosco |
| 18 Jul 21 |
r03 | | Benfica | - | Boavista |
| 18 Jul 21 |
r05 | | Rizespor | 2 - 3 | Kocaelispor |
| 18 Jul 21 |
r05 | | FSV Frankfur | 3 - 1 | Waldhof Mann |
| 18 Jul 21 |
r05 | | Rakow Czesto | 2 - 0 | Skra Często |
| 18 Jul 21 |
r05 | | Terek Grozny | 0 - 0 | Szombathelyi |
| 18 Jul 21 |
r05 | | Erzurumspor | 1 - 2 | Antalyaspor |
| 18 Jul 21 |
r04 | | Rudar Velenj | 1 - 0 | Nyíregyház |
| 18 Jul 21 |
r03 | | Nantes | 0 - 1 | Niort |
| 18 Jul 21 |
r03 | | Dortmund II | 1 - 2 | Preußen Mü |
| 18 Jul 21 |
r05 | | Bordeaux | 2 - 1 | Caen |
| 18 Jul 21 |
r03 | | Chievo | 1 - 1 | Virtus Veron |
| 18 Jul 21 |
r03 | | Salernitana | 6 - 0 | A.S.D. Citt� |
| 18 Jul 21 |
r05 | | Gaziantep FK | 1 - 5 | Malatyaspor |
| 18 Jul 21 |
r05 | | Atalanta | 1 - 1 | Maccabi Bnei |
| 18 Jul 21 |
r03 | | Elche | 6 - 1 | Atromitos |
| 18 Jul 21 |
r05 | | Mechelen | 1 - 3 | Westerlo |
| 18 Jul 21 |
r05 | | Portimonense | 0 - 0 | SC Farense |
| 18 Jul 21 |
r03 | | Westerlo | 1 - 3 | Mechelen |
| 18 Jul 21 |
r03 | | Covilha | 1 - 1 | Portimonense |
| 18 Jul 21 |
r05 | | Niort | 1 - 0 | Nantes |
| 18 Jul 21 |
r05 | | Hampton & Ri | - | Carshalton A |
| 18 Jul 21 |
r03 | | York | 1 - 0 | Newcastle |
| 18 Jul 21 |
r03 | | Club Brugge | 3 - 0 | Lierse Kempe |
| 18 Jul 21 |
r03 | | Krylya Sovet | 0 - 1 | Ural S.R |
| 18 Jul 21 |
r03 | | Harrogate To | - | Newcastle |
| 18 Jul 21 |
r03 | | FC Krasnodar | - | Bielefeld |
| 18 Jul 21 |
r03 | | Freiburg II | 1 - 0 | Mulhouse |
| 18 Jul 21 |
r02 | | Istanbul Bas | - | Sakaryaspor |
| 18 Jul 21 |
r03 | | Lüneburger | 0 - 2 | Lübeck |
| 18 Jul 21 |
r05 | | Desna | 2 - 0 | Veres Rivne |
| 18 Jul 21 |
r05 | | Rudar Pljevl | 1 - 0 | Nyíregyház |
| 18 Jul 21 |
r03 | | FC Koln | 2 - 0 | Schaffhausen |
| 18 Jul 21 |
r05 | | FC 03 Differ | 4 - 0 | UT Pétange |
| 18 Jul 21 |
r05 | | Tikveš | 0 - 1 | Renova |
| 18 Jul 21 |
r03 | | SC Dnipro-1 | 0 - 1 | Zorya |
| 18 Jul 21 |
r01 | | Roma | 2 - 0 | Ternana |
| 18 Jul 21 |
r03 | | Vizela | 0 - 1 | Maritimo |
| 18 Jul 21 |
r03 | | Spartak Mosc | 5 - 1 | Khimki FK |
| 18 Jul 21 |
r03 | | Khimki FK | 1 - 5 | Spartak Mosc |
| 18 Jul 21 |
r05 | | Poblense | 0 - 1 | Mallorca |
| 19 Jul 21 |
r05 | | Brønshøj | 1 - 0 | Hvidovre IF |
| 19 Jul 21 |
r05 | | Nyíregyház | 2 - 0 | Beitar Jerus |
| 19 Jul 21 |
r05 | | CSKA Moscow | 2 - 1 | Nizhny Novgo |
| 19 Jul 21 |
r03 | | Granada | 2 - 1 | Bournemouth |
| 19 Jul 21 |
r05 | | Aveley | 5 - 2 | East Thurroc |
| 19 Jul 21 |
r03 | | Genk | 5 - 2 | MVV Maastric |
| 19 Jul 21 |
r05 | | Terek Grozny | 2 - 2 | Al Fateh FC |
| 19 Jul 21 |
r01 | | Fenerbahce | 4 - 1 | Kasimpasa |
| 19 Jul 21 |
r05 | | Bournemouth | 0 - 0 | Granada |
| 19 Jul 21 |
r03 | | Bishops Stor | - | Kings Lynn T |
| 20 Jul 21 |
r05 | | Chippenham T | 1 - 2 | Newport |
| 20 Jul 21 |
r05 | | Carshalton A | 1 - 3 | Dartford |
| 20 Jul 21 |
r03 | | FC Porto | - | Anadia |
| 20 Jul 21 |
r05 | | Calahorra | 2 - 0 | Zaragoza |
| 20 Jul 21 |
r05 | | Northwich Vi | 1 - 5 | Chester City |
| 20 Jul 21 |
r04 | | Inđija | 2 - 0 | Borec |
| 20 Jul 21 |
r05 | | TSV Steinbac | 2 - 4 | Wuppertaler |
| 20 Jul 21 |
r05 | | Ein Frankfur | 6 - 1 | FC Gießen |
| 20 Jul 21 |
r03 | | Burnley | 4 - 0 | Salford City |
| 20 Jul 21 |
r03 | | Apoel Nicosi | 0 - 0 | Apollon Smir |
| 20 Jul 21 |
r03 | | Newry City A | 1 - 0 | Warrenpoint |
| 20 Jul 21 |
r03 | | Benfica B | 3 - 2 | Mafra |
| 20 Jul 21 |
r05 | | Kings Langle | 1 - 3 | Slough Town |
| 20 Jul 21 |
r03 | | Gillingham | - | Peterboro |
| 20 Jul 21 |
r05 | | Oxford Utd | 9 - 0 | Hayes & Yead |
| 20 Jul 21 |
r04 | | Salisbury | - | Havant & Wat |
| 20 Jul 21 |
r03 | | Burnley | 2 - 1 | Morecambe |
| 20 Jul 21 |
r03 | | TOP Oss | 2 - 2 | SV OSS 20 |
| 20 Jul 21 |
r03 | | Maritimo | 1 - 2 | F.C. Paços |
| 20 Jul 21 |
r03 | | Birmingham | 1 - 1 | Barrow |
| 20 Jul 21 |
r03 | | Stevenage | - | Ipswich |
| 20 Jul 21 |
r03 | | VV Noordwijk | - | Jong PSV |
| 20 Jul 21 |
r03 | | PEC Zwolle | 3 - 0 | Helmond Spor |
| 20 Jul 21 |
r03 | | Ath Bilbao | 1 - 0 | Dynamo Kiev |
| 20 Jul 21 |
r03 | | Sheffield We | 0 - 2 | West Brom |
| 20 Jul 21 |
r05 | | West Brom | 2 - 0 | Sheffield We |
| 20 Jul 21 |
r03 | | Bristol City | 3 - 3 | Portsmouth |
| 20 Jul 21 |
r05 | | Paris FC | - | Creteil |
| 20 Jul 21 |
r03 | | SC Telstar | - | SC Heracles |
| 20 Jul 21 |
r03 | | NFC Volos | 0 - 1 | KMSK Deinze |
| 20 Jul 21 |
r03 | | Norwich | 1 - 0 | Lincoln |
| 20 Jul 21 |
r05 | | Shakhtar Don | 5 - 0 | Obolon-Brova |
| 20 Jul 21 |
r03 | | Mansfield | 0 - 1 | Grimsby |
| 20 Jul 21 |
r05 | | FA 2000 | 0 - 0 | Vanløse |
| 20 Jul 21 |
r05 | | Wacker Innsb | 1 - 1 | Liverpool |
| 20 Jul 21 |
r05 | | Le Puy Foot | 1 - 2 | Bourg-Peronn |
| 20 Jul 21 |
r03 | | Rot-Weiss Es | 0 - 3 | FC Emmen |
| 20 Jul 21 |
r03 | | Lazio | - | A.C. Belluno |
| 20 Jul 21 |
r03 | | Real Socieda | 3 - 1 | Osasuna B |
| 20 Jul 21 |
r05 | | Al Ain | - | Al-Nasr Sala |
| 20 Jul 21 |
r03 | | VV ASWH | 0 - 1 | FC Dordrecht |
| 20 Jul 21 |
r05 | | Stuttgart | 1 - 0 | Wacker Innsb |
| 20 Jul 21 |
r03 | | Plymouth | 1 - 2 | Swansea |
| 20 Jul 21 |
r03 | | Rochdale | 2 - 2 | Rotherham |
| 20 Jul 21 |
r03 | | Kidderminste | 1 - 2 | Cheltenham |
| 20 Jul 21 |
r03 | | Forest Green | 1 - 2 | Cardiff |
| 20 Jul 21 |
r03 | | Bolton | 1 - 0 | Preston |
| 20 Jul 21 |
r03 | | Crewe | 2 - 3 | Stoke |
| 20 Jul 21 |
r05 | | Ebbsfleet Un | - | Colchester |
| 20 Jul 21 |
r03 | | Stalybridge | 1 - 3 | Tranmere |
| 20 Jul 21 |
r03 | | Weymouth | 2 - 3 | Exeter |
| 20 Jul 21 |
r05 | | Swindon | 3 - 2 | Swindon Supe |
| 20 Jul 21 |
r03 | | AFC Fylde | 0 - 1 | Wigan |
| 20 Jul 21 |
r03 | | Guiseley | 1 - 2 | Bradford |
| 20 Jul 21 |
r03 | | Swindon Supe | 2 - 3 | Swindon |
| 20 Jul 21 |
r03 | | Chorley | 0 - 2 | Carlisle |
| 20 Jul 21 |
r03 | | Scunthorpe | 2 - 1 | Burton |
| 20 Jul 21 |
r03 | | Boreham Wood | 0 - 2 | Brentford |
| 20 Jul 21 |
r03 | | Hereford | 1 - 2 | Shrewsbury |
| 20 Jul 21 |
r03 | | Metropolitan | 0 - 1 | AFC Wimbledo |
| 20 Jul 21 |
r05 | | Flint Town U | 3 - 1 | Marine |
| 20 Jul 21 |
r05 | | Bishops Stor | - | Kings Lynn T |
| 20 Jul 21 |
r03 | | Northampton | 0 - 2 | Nottingham F |
| 20 Jul 21 |
r03 | | St Albans Ci | 1 - 1 | Wealdstone |
| 20 Jul 21 |
r03 | | Kingstonian | 2 - 0 | AFC Wimbledo |
| 20 Jul 21 |
r05 | | Haringey Bor | 0 - 4 | Sutton Unite |
| 20 Jul 21 |
r03 | | Sporting CP | 2 - 0 | Angers |
| 21 Jul 21 |
r03 | | Wacker Innsb | - | Genoa |
| 21 Jul 21 |
r03 | | Anorthosis F | - | Hapoel Haifa |
| 21 Jul 21 |
r03 | | Real Oviedo | 2 - 0 | Rayo Majadah |
| 21 Jul 21 |
r03 | | Espanol | 0 - 1 | Las Palmas |
| 21 Jul 21 |
r04 | | Grafičar | 0 - 0 | Radnički Sr |
| 21 Jul 21 |
r04 | | Mosta FC | 1 - 8 | Balzan FC |
| 21 Jul 21 |
r05 | | Mallorca | 1 - 0 | Cartagena FC |
| 21 Jul 21 |
r05 | | Salernitana | 3 - 2 | Sambenedette |
| 21 Jul 21 |
r04 | | Sevenoaks To | 2 - 4 | Lewes |
| 21 Jul 21 |
r05 | | Osasuna | 2 - 1 | Huesca |
| 21 Jul 21 |
r05 | | Santander | 2 - 1 | SD Amorebiet |
| 21 Jul 21 |
r05 | | Paris SG | 2 - 1 | Augsburg |
| 21 Jul 21 |
r05 | | UD Ibiza | 2 - 0 | Al-Raed |
| 21 Jul 21 |
r04 | | Orijent 1919 | 3 - 0 | NK Inter Zap |
| 21 Jul 21 |
r05 | | CSA Steaua B | 2 - 2 | Metaloglobus |
| 21 Jul 21 |
r05 | | Skra Często | 0 - 2 | Aris Limasso |
| 21 Jul 21 |
r05 | | Reggina | 4 - 1 | A.S.D. Citt� |
| 21 Jul 21 |
r05 | | Zaglebie Lub | 2 - 2 | Górnik Polk |
| 21 Jul 21 |
r04 | | Skopje | 3 - 2 | Teteks |
| 21 Jul 21 |
r03 | | Hartford Ath | - | Western Mass |
| 21 Jul 21 |
r05 | | CD Nacional | 1 - 0 | Pevidém |
| 21 Jul 21 |
r05 | | Vilafranquen | 0 - 1 | Torreense |
| 21 Jul 21 |
r03 | | SC Heracles | 1 - 2 | PAOK |
| 21 Jul 21 |
r05 | | Roma | - | Triestina |
| 21 Jul 21 |
r03 | | Podbeskidzie | 0 - 2 | Chrobry Gło |
| 21 Jul 21 |
r05 | | Bačka Palan | 1 - 2 | Bregalnica � |
| 21 Jul 21 |
r03 | | Parma Calcio | 0 - 1 | Bochum |
| 21 Jul 21 |
r03 | | Stade de Rei | 0 - 2 | FC Chambly |
| 21 Jul 21 |
r05 | | Siófok | 0 - 0 | Al Hazm |
| 21 Jul 21 |
r05 | | FC Chambly | - | Stade de Rei |
| 21 Jul 21 |
r05 | | Renova | 0 - 1 | Rabotnichki |
| 21 Jul 21 |
r05 | | Inter | 4 - 0 | Pro Vercelli |
| 21 Jul 21 |
r03 | | St Etienne | - | Nice |
| 21 Jul 21 |
r05 | | FC Villefran | - | Jura Sud Foo |
| 21 Jul 21 |
r05 | | OFI | - | Fortuna Sitt |
| 21 Jul 21 |
r05 | | Solin | 0 - 1 | RNK Split |
| 21 Jul 21 |
r03 | | Fortuna Sitt | 1 - 1 | OFI |
| 21 Jul 21 |
r05 | | Eibar | - | SD Logroñé |
| 21 Jul 21 |
r05 | | Duisburg | 0 - 3 | VfB Homberg |
| 21 Jul 21 |
r03 | | Preußen Mü | 1 - 0 | Werder Breme |
| 21 Jul 21 |
r05 | | Vallecano | 2 - 2 | Al Shabab |
| 21 Jul 21 |
r05 | | Lugo | 1 - 0 | Ponferradina |
| 21 Jul 21 |
r05 | | Voltigeurs d | 0 - 1 | Laval |
| 21 Jul 21 |
r05 | | Las Palmas | 1 - 0 | Espanol |
| 21 Jul 21 |
r05 | | Epinal | 0 - 2 | Mulhouse |
| 21 Jul 21 |
r01 | | Barcelona | 4 - 0 | Gimnastic |
| 21 Jul 21 |
r03 | | Brest | 1 - 2 | Stade Brioch |
| 21 Jul 21 |
r05 | | Real Oviedo | - | Extremadura |
| 21 Jul 21 |
r03 | | Linense | 0 - 2 | Cadiz |
| 21 Jul 21 |
r03 | | Getafe | 2 - 1 | Rennes |
| 21 Jul 21 |
r03 | | Valencia | 3 - 0 | Atromitos |
| 21 Jul 21 |
r05 | | Eintracht Tr | 2 - 1 | Mondorf-les- |
| 21 Jul 21 |
r03 | | VV UNA | 2 - 0 | FC Den Bosch |
| 21 Jul 21 |
r01 | | Triestina | 0 - 1 | Roma |
| 21 Jul 21 |
r03 | | York | 1 - 1 | Sunderland |
| 21 Jul 21 |
r03 | | Blackpool | - | Rangers |
| 21 Jul 21 |
r03 | | Ashton | 0 - 2 | Stockport |
| 21 Jul 21 |
r03 | | Reading | 0 - 3 | West Ham |
| 21 Jul 21 |
r03 | | Vélez | 0 - 2 | Malaga |
| 21 Jul 21 |
r03 | | Harrogate To | 1 - 3 | Rotherham |
| 21 Jul 21 |
r05 | | Talavera | 0 - 2 | Alcorcon |
| 21 Jul 21 |
r03 | | Brighouse To | 1 - 3 | Bradford |
| 21 Jul 21 |
r03 | | Walsall | 0 - 4 | Aston Villa |
| 21 Jul 21 |
r03 | | Matlock | 1 - 3 | Chesterfield |
| 21 Jul 21 |
r01 | | Colchester | 0 - 3 | Tottenham |
| 21 Jul 21 |
r05 | | Gainsborough | 2 - 1 | Lincoln |
| 21 Jul 21 |
r03 | | Arbroath | 1 - 4 | St Johnstone |
| 21 Jul 21 |
r03 | | Braga | 1 - 1 | Marseille |
| 22 Jul 21 |
r03 | | Lyon | 2 - 2 | Villarreal |
| 22 Jul 21 |
r03 | | Hapoel Kirya | - | Al Sharjah |
| 22 Jul 21 |
r03 | | Kolubara | 1 - 1 | Hapoel Hader |
| 22 Jul 21 |
r05 | | Benevento | 2 - 2 | A.S.D. Citt� |
| 22 Jul 21 |
r00 | | Sevilla | 1 - 0 | Las Palmas |
| 22 Jul 21 |
r05 | | Stamford AFC | 1 - 3 | Kettering To |
| 22 Jul 21 |
r05 | | Beitar Jerus | 0 - 0 | AEK Larnaca |
| 22 Jul 21 |
r03 | | Olympiakos N | 2 - 1 | Doxa Katokop |
| 22 Jul 21 |
r01 | | Trabzonspor | 1 - 0 | Bandırmaspo |
| 22 Jul 21 |
r05 | | Makedonija G | 2 - 1 | Akademija Pa |
| 22 Jul 21 |
r05 | | Rad | 0 - 3 | Hapoel Kirya |
| 22 Jul 21 |
r05 | | Chelsea | - | Drogheda |
| 22 Jul 21 |
r00 | | Villarreal | 2 - 2 | Lyon |
| 22 Jul 21 |
r03 | | Benfica | 1 - 0 | Lille |
| 23 Jul 21 |
r05 | | Ternana | 3 - 0 | FC Grosseto |
| 23 Jul 21 |
r04 | | Szombathelyi | 1 - 1 | Al-Ettifaq |
| 23 Jul 21 |
r03 | | Hapoel Tel-A | 1 - 3 | Arka Gdynia |
| 23 Jul 21 |
r05 | | Stuttgart | 5 - 2 | Bielefeld |
| 23 Jul 21 |
r05 | | Dynamo Kiev | 1 - 1 | Union Berlin |
| 23 Jul 21 |
r05 | | Celta Vigo | 3 - 0 | Atlético Sa |
| 23 Jul 21 |
r03 | | Morecambe | 0 - 0 | Barnsley |
| 23 Jul 21 |
r05 | | Numancia | 1 - 1 | Ath Madrid |
| 23 Jul 21 |
r05 | | Leverkusen | 0 - 0 | Freiburg |
| 23 Jul 21 |
r03 | | Górnik Polk | 1 - 1 | Odra Opole |
| 23 Jul 21 |
r03 | | Korona Kielc | 2 - 1 | Sandecja Now |
| 23 Jul 21 |
r03 | | FC Groningen | - | FC Volendam |
| 23 Jul 21 |
r03 | | Norwich | 2 - 0 | Huddersfield |
| 23 Jul 21 |
r03 | | FC Groningen | - | SC Heerenvee |
| 23 Jul 21 |
r03 | | Roda JC | 2 - 4 | RKC Waalwijk |
| 23 Jul 21 |
r03 | | LKS Lodz | 3 - 0 | Znicz Pruszk |
| 23 Jul 21 |
r03 | | Apoel Nicosi | 0 - 1 | Bnei Sakhnin |
| 23 Jul 21 |
r05 | | Atalanta | - | Modena |
| 23 Jul 21 |
r03 | | Zaglebie Sos | 4 - 0 | Puszcza Niep |
| 23 Jul 21 |
r05 | | PAEEK | - | Onisilos |
| 23 Jul 21 |
r05 | | Arka Gdynia | 3 - 1 | Hapoel Tel-A |
| 23 Jul 21 |
r03 | | RasenBallspo | 1 - 2 | Montpellier |
| 23 Jul 21 |
r03 | | Brescia | - | Real Calepin |
| 23 Jul 21 |
r03 | | Sparta | 1 - 2 | NAC Breda |
| 23 Jul 21 |
r03 | | FC Dordrecht | 2 - 3 | Almere City |
| 23 Jul 21 |
r01 | | Liverpool | 1 - 0 | Mainz |
| 23 Jul 21 |
r01 | | Mainz | - | Liverpool |
| 23 Jul 21 |
r05 | | Stade Brioch | - | Concarneau |
| 23 Jul 21 |
r03 | | SSV Jeddeloh | 0 - 1 | Rödinghause |
| 23 Jul 21 |
r03 | | Lazio | 5 - 2 | Triestina |
| 23 Jul 21 |
r05 | | Santander | - | Sp Gijon B |
| 23 Jul 21 |
r03 | | FC Eindhoven | - | Lommel SK |
| 23 Jul 21 |
r03 | | Go Ahead Eag | 1 - 1 | Vitesse |
| 23 Jul 21 |
r03 | | VVV-Venlo | 1 - 4 | Helmond Spor |
| 23 Jul 21 |
r03 | | Atlas Delmen | 2 - 2 | VfL Oldenbur |
| 23 Jul 21 |
r05 | | Ath Madrid | 2 - 1 | Numancia |
| 23 Jul 21 |
r03 | | Unionistas d | - | Valladolid |
| 23 Jul 21 |
r05 | | Cambridge Un | 1 - 3 | Brentford |
| 23 Jul 21 |
r03 | | Plymouth | 1 - 2 | Middlesbroug |
| 23 Jul 21 |
r03 | | Doncaster | 2 - 3 | Newcastle |
| 23 Jul 21 |
r05 | | Mosta FC | - | Balzan FC |
| 23 Jul 21 |
r05 | | Stevenage | 1 - 0 | Crystal Pala |
| 23 Jul 21 |
r03 | | Wycombe | 3 - 1 | Aylesbury |
| 23 Jul 21 |
r05 | | Alfreton Tow | 1 - 2 | Mansfield |
| 23 Jul 21 |
r03 | | Aylesbury | 1 - 3 | Wycombe |
| 23 Jul 21 |
r03 | | Hampton & Ri | 1 - 1 | AFC Wimbledo |
| 24 Jul 21 |
r03 | | Salford City | 2 - 1 | Derby |
| 24 Jul 21 |
r05 | | Pisa | 1 - 1 | Cremonese |
| 24 Jul 21 |
r05 | | Bath City | 3 - 3 | Gloucester C |
| 24 Jul 21 |
r05 | | Hillerød | 1 - 1 | Frem |
| 24 Jul 21 |
r05 | | Monza | 3 - 0 | Pro Sesto |
| 24 Jul 21 |
r05 | | Blyth Sparta | 1 - 2 | South Shield |
| 24 Jul 21 |
r05 | | Eastbourne B | 1 - 2 | Kingstonian |
| 24 Jul 21 |
r05 | | Brønshøj | 0 - 4 | Roskilde |
| 24 Jul 21 |
r05 | | Hyde United | 4 - 4 | Bradford Par |
| 24 Jul 21 |
r05 | | Stalybridge | 1 - 2 | Curzon |
| 24 Jul 21 |
r05 | | Perugia | 6 - 0 | Montevarchi |
| 24 Jul 21 |
r05 | | Recreativo | 0 - 1 | Betis Deport |
| 24 Jul 21 |
r05 | | Petrolul | 2 - 1 | Concordia |
| 24 Jul 21 |
r03 | | Jong AZ | - | FC Volendam |
| 24 Jul 21 |
r05 | | Jong Volenda | 6 - 1 | Jong AZ |
| 24 Jul 21 |
r05 | | Chelmsford | 1 - 1 | Boreham Wood |
| 24 Jul 21 |
r05 | | Colchester | 0 - 2 | Gillingham |
| 24 Jul 21 |
r05 | | Vitesse | 0 - 1 | Lommel SK |
| 24 Jul 21 |
r05 | | Napoli | 1 - 0 | Pro Vercelli |
| 24 Jul 21 |
r03 | | Watford | 1 - 3 | Brentford |
| 24 Jul 21 |
r05 | | Brescia | 1 - 2 | Renate |
| 24 Jul 21 |
r05 | | Aris Limasso | 0 - 1 | Hapoel Jerus |
| 24 Jul 21 |
r05 | | Zalaegerszeg | 0 - 0 | AEK Larnaca |
| 24 Jul 21 |
r05 | | Badajoz | 2 - 1 | Benfica B |
| 24 Jul 21 |
r05 | | Extremadura | 0 - 3 | FC Porto B |
| 24 Jul 21 |
r03 | | Skive IK | 0 - 2 | Aarhus Frema |
| 24 Jul 21 |
r05 | | Ħamrun Spar | 2 - 1 | Balzan FC |
| 24 Jul 21 |
r03 | | Kolding IF | - | Silkeborg IF |
| 24 Jul 21 |
r01 | | Paris SG | 1 - 0 | Orleans |
| 24 Jul 21 |
r03 | | Debrecen | - | Diosgyor |
| 24 Jul 21 |
r05 | | Sirens FC | 0 - 1 | Floriana FC |
| 24 Jul 21 |
r03 | | Real Avilés | 0 - 1 | Real Oviedo |
| 24 Jul 21 |
r03 | | Trento | 2 - 4 | Parma Calcio |
| 24 Jul 21 |
r05 | | Mačva Šaba | 2 - 1 | Bačka Palan |
| 24 Jul 21 |
r03 | | Lecce | 0 - 0 | Legnago Salu |
| 24 Jul 21 |
r03 | | Coleraine | 0 - 2 | Annagh Unite |
| 24 Jul 21 |
r03 | | Cliftonville | 2 - 0 | Newry City A |
| 24 Jul 21 |
r05 | | Accrington | 1 - 1 | Preston |
| 24 Jul 21 |
r05 | | AB Gladsaxe | 0 - 4 | Næstved BK |
| 24 Jul 21 |
r03 | | Leganes | - | Talavera |
| 24 Jul 21 |
r05 | | Haringey Bor | 0 - 4 | Oxford City |
| 24 Jul 21 |
r05 | | Crusaders | 3 - 1 | H and W Weld |
| 24 Jul 21 |
r05 | | Kickers Offe | 5 - 1 | Bergisch Gla |
| 24 Jul 21 |
r05 | | Milan | 5 - 0 | Modena |
| 24 Jul 21 |
r05 | | Espanol | 0 - 2 | Vallecano |
| 24 Jul 21 |
r05 | | Ripensia Tim | 0 - 2 | FC Politehni |
| 24 Jul 21 |
r05 | | CSA Steaua B | 3 - 0 | Unirea Const |
| 24 Jul 21 |
r05 | | Sesvete | 0 - 1 | Kustošija |
| 24 Jul 21 |
r05 | | Juventus | 3 - 1 | Cesena |
| 24 Jul 21 |
r05 | | Socuéllamos | 1 - 4 | Linares Depo |
| 24 Jul 21 |
r05 | | SD Amorebiet | 1 - 1 | UD Logroñé |
| 24 Jul 21 |
r05 | | Osasuna B | 1 - 0 | SD Logroñé |
| 24 Jul 21 |
r05 | | B.93 | 4 - 0 | FA 2000 |
| 24 Jul 21 |
r05 | | Sioni | 3 - 0 | Metalurgi Ru |
| 24 Jul 21 |
r05 | | Al Ain | 0 - 1 | UCAM Murcia |
| 24 Jul 21 |
r05 | | FC Hermannst | 1 - 1 | 1599 Șelimb |
| 24 Jul 21 |
r03 | | Getafe | 3 - 0 | Atromitos |
| 24 Jul 21 |
r03 | | Jastrzębie | 2 - 5 | Tychy 71 |
| 24 Jul 21 |
r03 | | Tychy 71 | - | Jastrzębie |
| 24 Jul 21 |
r03 | | Nantes | 3 - 1 | Brest |
| 24 Jul 21 |
r03 | | Paksi FC | 2 - 0 | Budafoki MTE |
| 24 Jul 21 |
r05 | | Brest | 1 - 3 | Nantes |
| 24 Jul 21 |
r05 | | Stuttgart II | 1 - 4 | Bahlinger SC |
| 24 Jul 21 |
r03 | | Real Socieda | 1 - 2 | Eibar |
| 24 Jul 21 |
r05 | | Osasuna | 2 - 0 | Burgos |
| 24 Jul 21 |
r03 | | Ath Bilbao | 0 - 1 | Mirandes |
| 24 Jul 21 |
r05 | | Skive IK | 0 - 2 | VSK Århus |
| 24 Jul 21 |
r03 | | FC Den Bosch | 1 - 2 | MVV Maastric |
| 24 Jul 21 |
r05 | | Middelfart | - | Hellerup IK |
| 24 Jul 21 |
r05 | | Radomiak Rad | 2 - 1 | Bełchatów |
| 24 Jul 21 |
r05 | | Lens | 2 - 1 | Stade de Rei |
| 24 Jul 21 |
r03 | | De Graafscha | 2 - 1 | SC Telstar |
| 24 Jul 21 |
r03 | | Hull | 1 - 2 | Mansfield |
| 24 Jul 21 |
r03 | | Willem II | 4 - 1 | Lierse Kempe |
| 24 Jul 21 |
r03 | | SC Heracles | 0 - 1 | NEC Nijmegen |
| 24 Jul 21 |
r03 | | Bromley | 4 - 0 | Ebbsfleet Un |
| 24 Jul 21 |
r03 | | Grimsby | 0 - 1 | Rotherham |
| 24 Jul 21 |
r03 | | Hoffenheim | - | SPVGG Greuth |
| 24 Jul 21 |
r03 | | Sheffield We | - | Wrexham |
| 24 Jul 21 |
r03 | | Oldham | 0 - 2 | Burnley |
| 24 Jul 21 |
r05 | | ADO Den Haag | 2 - 2 | FC Twente |
| 24 Jul 21 |
r03 | | Jong PSV | 1 - 4 | Schalke 04 I |
| 24 Jul 21 |
r03 | | St Johnstone | 0 - 0 | Fleetwood To |
| 24 Jul 21 |
r03 |  | Jong Utrecht | - | Go Ahead Eag |
| 24 Jul 21 |
r03 | | Leamington | 0 - 0 | Forest Green |
| 24 Jul 21 |
r03 | | Eintracht No | 3 - 0 | Greifswalder |
| 24 Jul 21 |
r03 | | Cardiff | 2 - 2 | Exeter |
| 24 Jul 21 |
r05 | | Arsenal | 4 - 1 | Millwall |
| 24 Jul 21 |
r03 | | PEC Zwolle | 2 - 1 | SC Cambuur |
| 24 Jul 21 |
r03 | | Stade de Rei | 1 - 2 | Lens |
| 24 Jul 21 |
r03 | | Bristol City | 3 - 1 | Milton Keyne |
| 24 Jul 21 |
r05 | | Atlas Delmen | 4 - 1 | Bremer SV |
| 24 Jul 21 |
r03 | | Schwarz-Wei� | 0 - 2 | Preußen Mü |
| 24 Jul 21 |
r03 | | Reading | 1 - 1 | Charlton |
| 24 Jul 21 |
r05 | | Barnet | 2 - 3 | Peterboro |
| 24 Jul 21 |
r03 | | Mönchenglad | 1 - 0 | Metz |
| 24 Jul 21 |
r05 | | Kidderminste | 0 - 5 | Walsall |
| 24 Jul 21 |
r05 | | Needham Mark | 2 - 0 | Brightlingse |
| 24 Jul 21 |
r05 | | Chorley | 0 - 2 | Dorking Wand |
| 24 Jul 21 |
r03 | | Carlisle | 0 - 1 | Blackpool |
| 24 Jul 21 |
r01 | | QPR | 4 - 2 | Manchester U |
| 24 Jul 21 |
r01 | | Dortmund | 0 - 2 | Ath Bilbao |
| 24 Jul 21 |
r03 | | L.R. Vicenza | 0 - 3 | Cagliari |
| 24 Jul 21 |
r03 | | Poole Town F | 0 - 2 | Torquay |
| 24 Jul 21 |
r03 | | Hornchurch | 0 - 3 | Dagenham & R |
| 24 Jul 21 |
r03 | | Stoke | 2 - 0 | Aston Villa |
| 24 Jul 21 |
r03 | | AFC Fylde | 0 - 1 | Rochdale |
| 24 Jul 21 |
r03 | | Warrington T | 0 - 1 | Tranmere |
| 24 Jul 21 |
r03 | | Nice | 0 - 2 | Union Berlin |
| 24 Jul 21 |
r03 | | Birmingham | - | Oxford Utd |
| 24 Jul 21 |
r03 | | Bristol Rove | - | Swansea |
| 24 Jul 21 |
r03 | | Crewe | 2 - 2 | Nottingham F |
| 24 Jul 21 |
r03 | | Scunthorpe | 0 - 1 | Hull |
| 24 Jul 21 |
r03 | | Harrogate To | 0 - 4 | Sunderland |
| 24 Jul 21 |
r05 | | East Thurroc | - | Concord Rang |
| 24 Jul 21 |
r03 | | Ipswich | 0 - 1 | Crystal Pala |
| 24 Jul 21 |
r03 | | Maidenhead U | 1 - 2 | Leyton Orien |
| 24 Jul 21 |
r03 | | Barrow | 0 - 1 | Bolton |
| 24 Jul 21 |
r03 | | Burton | 0 - 0 | Leicester |
| 24 Jul 21 |
r03 | | Ashton | 0 - 2 | Altrincham |
| 24 Jul 21 |
r03 | | Banbury | 1 - 1 | Solihull Moo |
| 24 Jul 21 |
r03 | | Maidstone | - | Southend |
| 24 Jul 21 |
r03 | | Luton | 1 - 1 | Portsmouth |
| 24 Jul 21 |
r00 | | AFC Telford | 0 - 1 | Notts County |
| 24 Jul 21 |
r03 | | Wolfsburg | 1 - 2 | Monaco |
| 24 Jul 21 |
r03 | | Stratford To | 0 - 1 | Yeovil |
| 24 Jul 21 |
r05 | | Brighouse To | 2 - 3 | Matlock |
| 24 Jul 21 |
r05 | | Union Berlin | 2 - 0 | Nice |
| 24 Jul 21 |
r03 | | Northampton | 3 - 2 | Birmingham |
| 24 Jul 21 |
r03 | | Watford | 0 - 0 | West Brom |
| 24 Jul 21 |
r03 | | Celtic | 2 - 6 | West Ham |
| 24 Jul 21 |
r03 | | Dartford | 1 - 0 | AFC Wimbledo |
| 24 Jul 21 |
r03 | | Derby | 2 - 1 | Salford City |
| 24 Jul 21 |
r03 | | Bradford | 2 - 0 | Blackburn |
| 24 Jul 21 |
r03 | | Weymouth | 1 - 0 | Swindon |
| 24 Jul 21 |
r03 | | Metropolitan | - | Eastleigh |
| 24 Jul 21 |
r03 | | Dover | 2 - 1 | Folkestone I |
| 24 Jul 21 |
r03 | | Cheltenham | 2 - 0 | Coventry |
| 24 Jul 21 |
r04 | | Radcliffe | 1 - 2 | Chester City |
| 24 Jul 21 |
r03 | | Bologna | 1 - 0 | Feralpisalò |
| 24 Jul 21 |
r01 | | Bayern Munic | 2 - 2 | Ajax |
| 24 Jul 21 |
r03 | | Bochum | - | Torino |
| 24 Jul 21 |
r05 | | Lorient | - | Bordeaux |
| 24 Jul 21 |
r03 | | Miedz Legnic | 2 - 0 | Chrobry Gło |
| 24 Jul 21 |
r05 | | Spezia | - | Lecce |
| 24 Jul 21 |
r05 | | Fenerbahce | - | Udinese |
| 24 Jul 21 |
r05 | | Reggina | - | Sambenedette |
| 24 Jul 21 |
r03 | | Westerlo | 1 - 0 | OFI |
| 24 Jul 21 |
r03 | | Bordeaux | 1 - 1 | Lorient |
| 24 Jul 21 |
r03 | | Gyor | 1 - 1 | Kisvárda FC |
| 24 Jul 21 |
r05 | | Renova | - | Egnatia |
| 24 Jul 21 |
r03 | | FC Koln | 2 - 1 | Elversberg |
| 24 Jul 21 |
r03 | | Chrobry Gło | - | Miedz Legnic |
| 24 Jul 21 |
r03 | | Ein Frankfur | 2 - 3 | Strasbourg |
| 24 Jul 21 |
r03 | | Verona | 0 - 0 | Virtus Veron |
| 24 Jul 21 |
r03 | | Angers | 3 - 0 | Troyes |
| 24 Jul 21 |
r05 | | IMT Novi Beo | 0 - 2 | Al Feiha |
| 24 Jul 21 |
r05 | | Diosgyor | 1 - 1 | Al Hazm |
| 24 Jul 21 |
r05 | | Parma Calcio | 4 - 2 | Trento |
| 24 Jul 21 |
r03 | | Sassuolo | 0 - 0 | Sudtirol |
| 24 Jul 21 |
r05 | | Jeunesse Esc | 2 - 2 | Swift Hesper |
| 24 Jul 21 |
r05 | | Le Mans | 3 - 1 | FC Versaille |
| 24 Jul 21 |
r05 | | Orleans | - | Laval |
| 24 Jul 21 |
r03 | | Rennes | 1 - 3 | Levante |
| 24 Jul 21 |
r03 | | FC Utrecht | 6 - 2 | NFC Volos |
| 24 Jul 21 |
r05 | | Szombathelyi | - | Siófok |
| 24 Jul 21 |
r03 | | St Etienne | 2 - 3 | Clermont Foo |
| 24 Jul 21 |
r01 | | Trabzonspor | 0 - 0 | Istanbul Bas |
| 24 Jul 21 |
r03 | | Sutton Unite | 1 - 2 | Aldershot |
| 24 Jul 21 |
r03 | | Levante | 3 - 1 | Rennes |
| 24 Jul 21 |
r03 | | Rangers | 0 - 0 | Brighton |
| 24 Jul 21 |
r05 | | Paris SG | - | Genoa |
| 24 Jul 21 |
r05 | | Alaves | 1 - 3 | Sociedad |
| 24 Jul 21 |
r03 | | Betis | 0 - 1 | Wolves |
| 24 Jul 21 |
r03 | | Malaga | 2 - 0 | Sevilla Atle |
| 24 Jul 21 |
r03 | | Valencia | 3 - 2 | Cartagena FC |
| 24 Jul 21 |
r01 | | Barcelona | 3 - 1 | Girona |
| 24 Jul 21 |
r03 | | Sociedad | 3 - 1 | Alaves |
| 24 Jul 21 |
r03 | | UD Ibiza | 1 - 2 | Mallorca |
| 24 Jul 21 |
r03 | | Kispest Honv | - | Villarreal |
| 24 Jul 21 |
r03 | | Ponferradina | - | Valladolid |
| 24 Jul 21 |
r03 | | Algeciras CF | 0 - 4 | Cadiz |
| 24 Jul 21 |
r05 | | Braga | - | F.C. Paços |
| 24 Jul 21 |
r03 | | Elche | - | Zaragoza |
| 24 Jul 21 |
r03 | | F.C. Paços | 2 - 1 | Braga |
| 25 Jul 21 |
r03 | | Anorthosis F | 2 - 0 | Doxa Katokop |
| 25 Jul 21 |
r04 | | Bačka Palan | 0 - 2 | Zlatibor Ča |
| 25 Jul 21 |
r03 | | Águilas | 0 - 1 | Almeria |
| 25 Jul 21 |
r05 | | Erzurumspor | 1 - 2 | Konyaspor |
| 25 Jul 21 |
r05 | | AZ Alkmaar | 3 - 0 | Panathinaiko |
| 25 Jul 21 |
r05 | | Goztepe | 1 - 1 | Ümraniyespo |
| 25 Jul 21 |
r05 | | Lamia | 2 - 2 | Ethnikos Ach |
| 25 Jul 21 |
r05 | | Sp Gijon | 2 - 0 | Racing Club |
| 25 Jul 21 |
r05 | | Badajoz | 0 - 1 | FC Porto B |
| 25 Jul 21 |
r05 | | Szombathelyi | 1 - 3 | Siófok |
| 25 Jul 21 |
r05 | | Antalyaspor | 4 - 1 | Menemen Bele |
| 25 Jul 21 |
r05 | | Salernitana | 0 - 1 | Gubbio |
| 25 Jul 21 |
r05 | | Struga | 2 - 0 | Gjilani |
| 25 Jul 21 |
r02 | | Gaziantep FK | 2 - 3 | Dynamo Kiev |
| 25 Jul 21 |
r03 | | AZ Alkmaar | - | Panetolikos |
| 25 Jul 21 |
r03 | | Pordenone Ca | 2 - 1 | Gorica |
| 25 Jul 21 |
r05 | | Vasas | 2 - 2 | Soroksár |
| 25 Jul 21 |
r05 | | DEAC | 1 - 0 | Békéscsaba |
| 25 Jul 21 |
r03 | | Hannover II | 2 - 0 | Teutonia Ott |
| 25 Jul 21 |
r02 | | Alanyaspor | - | Adana Demirs |
| 25 Jul 21 |
r03 | | FC Emmen | 4 - 1 | SC Heracles |
| 25 Jul 21 |
r01 | | Feyenoord | 1 - 2 | PAOK |
| 25 Jul 21 |
r05 | | SO Cholet | 0 - 1 | Voltigeurs d |
| 25 Jul 21 |
r05 | | Fiorentina | - | A.S.D. Citt� |
| 25 Jul 21 |
r05 | | Atalanta | - | Pergolettese |
| 25 Jul 21 |
r05 | | FC 03 Differ | 3 - 2 | Rodange |
| 25 Jul 21 |
r05 | | Dynamo Kiev | 3 - 2 | Gaziantep FK |
| 25 Jul 21 |
r05 | | Podbeskidzie | - | Gorica |
| 25 Jul 21 |
r03 | | III Kerület | 1 - 2 | Újpest FC |
| 25 Jul 21 |
r05 | | Potenza | 0 - 3 | SSD Palermo |
| 25 Jul 21 |
r01 | | Roma | 5 - 2 | Debrecen |
| 25 Jul 21 |
r01 | | Rangers | 2 - 1 | Real Madrid |
| 25 Jul 21 |
r03 | | FC Porto | 2 - 0 | Lille |
| 25 Jul 21 |
r03 | | Benfica | 1 - 1 | Marseille |
| 25 Jul 21 |
r03 | | Sporting CP | 3 - 2 | Lyon |
| 25 Jul 21 |
r05 | | Arsenal | - | Inter |
| 25 Jul 21 |
r05 | | Everton | 2 - 1 | Millonarios |
| 25 Jul 21 |
r05 | | Everton | 1 - 1 | Millonarios |
| 26 Jul 21 |
r05 | | Las Palmas | 3 - 2 | Wolves |
| 26 Jul 21 |
r05 | | Genclerbirli | 0 - 4 | Fenerbahce |
| 26 Jul 21 |
r05 | | Hendon | 2 - 0 | Hampton & Ri |
| 26 Jul 21 |
r05 | | Sampdoria | 2 - 0 | Piacenza |
| 26 Jul 21 |
r01 | | Trabzonspor | 2 - 1 | Kasimpasa |
| 26 Jul 21 |
r03 | | Chelmsford | 1 - 1 | Kings Lynn T |
| 27 Jul 21 |
r05 | | Cadiz | 0 - 2 | Las Palmas |
| 27 Jul 21 |
r05 | | Granada | 1 - 1 | Espanol |
| 27 Jul 21 |
r05 | | Cliftonville | 3 - 2 | Ards |
| 27 Jul 21 |
r05 | | Armagh City | 0 - 1 | Warrenpoint |
| 27 Jul 21 |
r05 | | Bournemouth | 1 - 2 | Chelsea |
| 27 Jul 21 |
r05 | | Karlslunde | 1 - 1 | FA 2000 |
| 27 Jul 21 |
r03 | | Apoel Nicosi | - | CSKA Sofia |
| 27 Jul 21 |
r05 | | Stourbridge | 0 - 1 | Solihull Moo |
| 27 Jul 21 |
r05 | | Manchester C | 2 - 0 | Preston |
| 27 Jul 21 |
r05 | | Besiktas | 1 - 0 | Istanbul Bas |
| 27 Jul 21 |
r03 | | FC Andorra | 0 - 1 | UD Ibiza |
| 27 Jul 21 |
r05 | | Kayserispor | 1 - 1 | Ballkani |
| 27 Jul 21 |
r05 | | Blyth Sparta | 2 - 1 | Hartlepool |
| 27 Jul 21 |
r05 | | Mainz | 1 - 0 | Gaziantep FK |
| 27 Jul 21 |
r03 | | Pirin Blagoe | 0 - 4 | Apoel Nicosi |
| 27 Jul 21 |
r03 | | Al Nasr | 1 - 1 | Cartagena FC |
| 27 Jul 21 |
r04 | | Opatija | 2 - 3 | Orijent 1919 |
| 27 Jul 21 |
r01 | | Paris SG | 2 - 2 | Sevilla |
| 27 Jul 21 |
r05 | | York | 2 - 1 | Middlesbroug |
| 27 Jul 21 |
r03 | | Exeter | 0 - 4 | Bristol City |
| 27 Jul 21 |
r05 | | Osnabrueck | 9 - 0 | Sportfreunde |
| 27 Jul 21 |
r03 | | Genk | 1 - 3 | Molenbeek |
| 27 Jul 21 |
r05 | | Rabotnichki | 0 - 0 | Gjilani |
| 27 Jul 21 |
r05 | | Samsunspor | 2 - 1 | Bursaspor |
| 27 Jul 21 |
r05 | | Annecy | 3 - 0 | Besançon Fo |
| 27 Jul 21 |
r05 | | Tabor Sežan | - | Fenerbahce |
| 27 Jul 21 |
r05 | | Apoel Nicosi | 4 - 0 | Pirin Blagoe |
| 27 Jul 21 |
r03 | | Torino | 0 - 0 | Al Fateh FC |
| 27 Jul 21 |
r05 | | Frem | - | FC Helsingoe |
| 27 Jul 21 |
r05 | | Al Feiha | 3 - 2 | Ajman |
| 27 Jul 21 |
r03 | | Lazio | 1 - 1 | Calcio Padov |
| 27 Jul 21 |
r05 | | Vannes OC | 1 - 1 | Stade Brioch |
| 27 Jul 21 |
r05 | | Hessen Kasse | 0 - 0 | KSV Baunatal |
| 27 Jul 21 |
r05 | | Stade Plaben | 3 - 2 | Concarneau |
| 27 Jul 21 |
r05 | | Oxford Utd | - | Peterboro |
| 27 Jul 21 |
r03 | | Rijnsburgse | 1 - 2 | SC Telstar |
| 27 Jul 21 |
r03 | | Levante | 2 - 1 | Atromitos |
| 27 Jul 21 |
r05 | | Cartagena FC | 1 - 1 | Al-Nasr Sala |
| 27 Jul 21 |
r01 | | Mallorca | - | Besiktas |
| 27 Jul 21 |
r03 | | NAC Breda | 1 - 2 | Almere City |
| 27 Jul 21 |
r03 | | Plymouth | 0 - 1 | Bristol City |
| 27 Jul 21 |
r03 | | Crystal Pala | 2 - 2 | Charlton |
| 27 Jul 21 |
r03 | | De Treffers | 0 - 0 | De Graafscha |
| 27 Jul 21 |
r05 | | Dollingstown | 1 - 1 | Loughgall |
| 27 Jul 21 |
r03 | | Tranmere | 0 - 0 | Sunderland |
| 27 Jul 21 |
r03 | | Bristol Rove | 0 - 0 | Havant & Wat |
| 27 Jul 21 |
r03 | | Gillingham | 1 - 1 | Millwall |
| 27 Jul 21 |
r03 | | Mansfield | 1 - 0 | Coventry |
| 27 Jul 21 |
r03 | | Cambridge Un | 1 - 2 | QPR |
| 27 Jul 21 |
r03 | | Oldham | 2 - 1 | Crewe |
| 27 Jul 21 |
r03 | | Fleetwood To | 2 - 1 | Huddersfield |
| 27 Jul 21 |
r03 | | Brackley Tow | - | Northampton |
| 27 Jul 21 |
r03 | | Cardiff | 0 - 4 | Southampton |
| 27 Jul 21 |
r03 | | Havant & Wat | - | Bristol Rove |
| 27 Jul 21 |
r05 | | Sevilla | 2 - 2 | Paris SG |
| 27 Jul 21 |
r03 | | Rotherham | 1 - 1 | Newcastle |
| 27 Jul 21 |
r03 | | Scunthorpe | 0 - 2 | Lincoln |
| 27 Jul 21 |
r03 | | Barnet | - | Swindon |
| 27 Jul 21 |
r05 | | Worthing | 5 - 1 | Welling Unit |
| 27 Jul 21 |
r03 | | Wigan | 2 - 1 | Stoke |
| 27 Jul 21 |
r03 | | Chesham Unit | 1 - 4 | Wealdstone |
| 27 Jul 21 |
r03 | | Warrington T | 0 - 2 | Accrington |
| 27 Jul 21 |
r03 | | Walsall | - | West Brom |
| 27 Jul 21 |
r05 | | Chorley | 0 - 1 | Bolton |
| 27 Jul 21 |
r03 | | Hungerford T | - | Cheltenham |
| 27 Jul 21 |
r03 | | Darlington F | 1 - 5 | Harrogate To |
| 27 Jul 21 |
r03 | | Dartford | 3 - 1 | Sutton Unite |
| 27 Jul 21 |
r03 | | Woking | 1 - 0 | AFC Wimbledo |
| 27 Jul 21 |
r03 | | Port Vale | 1 - 2 | Sheffield We |
| 27 Jul 21 |
r05 | | Whitby Town | 0 - 2 | Spennymoor T |
| 27 Jul 21 |
r03 | | Wimborne Tow | 1 - 1 | Eastleigh |
| 27 Jul 21 |
r03 | | Chesterfield | 2 - 1 | Bradford |
| 27 Jul 21 |
r03 | | Guiseley | 2 - 3 | Leeds |
| 27 Jul 21 |
r05 | | Stafford Ran | 3 - 1 | Hednesford T |
| 27 Jul 21 |
r05 | | Southport | 2 - 0 | Marine |
| 27 Jul 21 |
r03 | | Blackpool | 0 - 1 | Burnley |
| 27 Jul 21 |
r03 | | Haringey Bor | 0 - 0 | Aldershot |
| 27 Jul 21 |
r05 | | Chelsea | - | Bournemouth |
| 27 Jul 21 |
r03 | | Colchester | 3 - 3 | Ipswich |
| 27 Jul 21 |
r03 | | Hereford | 1 - 8 | Cheltenham |
| 27 Jul 21 |
r03 | | Boston Unite | 1 - 3 | Notts County |
| 27 Jul 21 |
r03 | | Alfreton Tow | 2 - 1 | Burton |
| 27 Jul 21 |
r03 | | Enfield Town | 1 - 4 | Boreham Wood |
| 27 Jul 21 |
r03 | | Curzon | 0 - 1 | Salford City |
| 27 Jul 21 |
r03 | | Nantwich Tow | 0 - 3 | Altrincham |
| 27 Jul 21 |
r03 | | Farsley Celt | 0 - 0 | Halifax |
| 27 Jul 21 |
r03 | | Torquay | 3 - 0 | Truro City |
| 27 Jul 21 |
r03 | | Stevenage | 1 - 1 | Watford |
| 27 Jul 21 |
r05 | | Dorchester T | 0 - 3 | Hungerford T |
| 28 Jul 21 |
r05 | | Compostela | 0 - 3 | Lugo |
| 28 Jul 21 |
r05 | | Fenerbahce | 2 - 2 | PEC Zwolle |
| 28 Jul 21 |
r05 | | Empoli | 3 - 0 | Pontedera |
| 28 Jul 21 |
r05 | | Alessandria | 4 - 1 | Renate |
| 28 Jul 21 |
r03 | | Onisilos | 1 - 6 | Olympiakos N |
| 28 Jul 21 |
r05 | | FC Porto | 1 - 1 | Roma |
| 28 Jul 21 |
r05 | | Alaves | 1 - 0 | Mirandes |
| 28 Jul 21 |
r05 | | FC Gießen | 0 - 3 | Wuppertaler |
| 28 Jul 21 |
r05 | | Lamia | 0 - 1 | Apollon Smir |
| 28 Jul 21 |
r03 | | Casa Pia | 0 - 0 | União de Sa |
| 28 Jul 21 |
r05 | | Sp Gijon | 0 - 2 | Real Socieda |
| 28 Jul 21 |
r05 | | Elversberg | 4 - 1 | Eintracht Tr |
| 28 Jul 21 |
r05 | | Granada | 0 - 1 | Alcorcon |
| 28 Jul 21 |
r05 | | UCAM Murcia | 0 - 1 | CA Pulpileñ |
| 28 Jul 21 |
r05 | | Anorthosis F | 4 - 1 | PAEEK |
| 28 Jul 21 |
r04 | | Sevenoaks To | 1 - 0 | Tonbridge An |
| 28 Jul 21 |
r03 | | Omonia Nicos | 5 - 1 | Olympiada Ly |
| 28 Jul 21 |
r05 | | Türkgücü | 1 - 0 | Sonnenhof Gr |
| 28 Jul 21 |
r05 | | Frosinone | 1 - 2 | Viterbese |
| 28 Jul 21 |
r05 | | Bellinzona | 1 - 0 | Lugano |
| 28 Jul 21 |
r05 | | Udinese | 2 - 3 | Sturm Graz |
| 28 Jul 21 |
r05 | | Inter | 6 - 0 | Crotone |
| 28 Jul 21 |
r05 | | Antalyaspor | 1 - 1 | Ümraniyespo |
| 28 Jul 21 |
r03 | | AEK Larnaca | 0 - 0 | Dhamk |
| 28 Jul 21 |
r04 | | Cayón | 0 - 3 | Santander |
| 28 Jul 21 |
r04 | | Xerez Deport | 2 - 1 | Real Madrid |
| 28 Jul 21 |
r03 | | SD Amorebiet | 0 - 1 | Osasuna |
| 28 Jul 21 |
r03 | | Leonesa | 2 - 1 | Real Oviedo |
| 28 Jul 21 |
r03 | | Alcorcon | - | Crotone |
| 28 Jul 21 |
r03 | | Pafos FC | 2 - 0 | Coruxo |
| 28 Jul 21 |
r04 | | Al Shabab | - | Linense |
| 28 Jul 21 |
r04 | | SD Logroñé | 0 - 0 | Osasuna B |
| 28 Jul 21 |
r05 | | Altay | 3 - 0 | Giresunspor |
| 28 Jul 21 |
r05 | | Renova | 2 - 2 | Vardar |
| 28 Jul 21 |
r05 | | Augsburg | - | SPVGG Greuth |
| 28 Jul 21 |
r03 | | Aston Villa | - | Nottingham F |
| 28 Jul 21 |
r03 | | Oxford Utd | 2 - 2 | Peterboro |
| 28 Jul 21 |
r05 | | Sioni | - | Samgurali |
| 28 Jul 21 |
r03 | | Nantes | 0 - 1 | Lorient |
| 28 Jul 21 |
r02 | | Alanyaspor | 2 - 2 | Hatayspor |
| 28 Jul 21 |
r03 | | AZ Alkmaar | 2 - 0 | OFI |
| 28 Jul 21 |
r05 | | Konyaspor | - | Goztepe |
| 28 Jul 21 |
r05 | | Arsenal | 4 - 1 | Watford |
| 28 Jul 21 |
r03 | | Leverkusen | 1 - 5 | FC Utrecht |
| 28 Jul 21 |
r05 | | Beitar Tel A | 1 - 3 | Hapoel Ramat |
| 28 Jul 21 |
r05 | | Saburtalo Tb | 2 - 1 | Sabah FC |
| 28 Jul 21 |
r03 | | Doxa Katokop | 2 - 0 | Karmiotissa |
| 28 Jul 21 |
r05 | | Olympiakos N | 6 - 1 | Onisilos |
| 28 Jul 21 |
r05 | | Viterbese | - | Frosinone |
| 28 Jul 21 |
r03 | | Troyes | 1 - 2 | Metz |
| 28 Jul 21 |
r05 | | Entella | - | SC Ligorna 1 |
| 28 Jul 21 |
r05 | | Dinamo Zagre | 2 - 1 | Međimurje |
| 28 Jul 21 |
r05 | | Skenderbeu | 1 - 3 | Gjilani |
| 28 Jul 21 |
r01 | | Bayern Munic | 0 - 2 | Mönchenglad |
| 28 Jul 21 |
r03 | | Sociedad | 2 - 1 | Monaco |
| 28 Jul 21 |
r04 | | Slagelse B&I | - | Holbæk B&I |
| 28 Jul 21 |
r05 | | SD Amorebiet | - | Osasuna B |
| 28 Jul 21 |
r05 | | Hertha | - | Villarreal |
| 28 Jul 21 |
r05 | | Real Oviedo | 1 - 2 | Leonesa |
| 28 Jul 21 |
r03 | | Valencia | 0 - 2 | Zaragoza |
| 28 Jul 21 |
r03 | | Elche | 2 - 2 | Tenerife |
| 28 Jul 21 |
r05 | | SD Logroñé | - | Burgos |
| 28 Jul 21 |
r03 | | Stade Plaben | 2 - 4 | Brest |
| 28 Jul 21 |
r03 | | Leganes | 2 - 1 | Rayo Majadah |
| 28 Jul 21 |
r05 | | Coventry | - | Norwich |
| 28 Jul 21 |
r01 | | SV Salzburg | 1 - 0 | Ath Madrid |
| 28 Jul 21 |
r03 | | Doncaster | 0 - 4 | Sheffield Un |
| 28 Jul 21 |
r03 | | Derby | 1 - 0 | Betis |
| 28 Jul 21 |
r05 | | San Roque Le | 0 - 0 | Sevilla Atle |
| 28 Jul 21 |
r03 | | Forest Green | 1 - 2 | Swansea |
| 28 Jul 21 |
r05 | | Bognor Regis | - | Portsmouth |
| 28 Jul 21 |
r03 | | Wycombe | 1 - 0 | Leicester |
| 28 Jul 21 |
r03 | | Blackburn | 1 - 1 | Leeds |
| 28 Jul 21 |
r03 | | Basford Utd. | 0 - 3 | Mansfield |
| 28 Jul 21 |
r01 | | Milton Keyne | 1 - 3 | Tottenham |
| 28 Jul 21 |
r03 | | Lancaster Ci | - | Carlisle |
| 28 Jul 21 |
r05 | | Marseille | 2 - 1 | St Etienne |
| 28 Jul 21 |
r01 | | Manchester U | 2 - 2 | Brentford |
| 28 Jul 21 |
r03 | | St Etienne | 1 - 2 | Marseille |
| 28 Jul 21 |
r05 | | Everton | 1 - 0 | Pumas |
| 29 Jul 21 |
r04 | | Al Shabab | 3 - 2 | Algeciras CF |
| 29 Jul 21 |
r04 | | FC Andorra | 2 - 0 | Villarreal B |
| 29 Jul 21 |
r03 | | Wiedenbrück | 1 - 1 | Schwarz-Wei� |
| 29 Jul 21 |
r05 | | Benevento | 3 - 1 | Reggina |
| 29 Jul 21 |
r05 | | Pisa | 1 - 0 | Pro Sesto |
| 29 Jul 21 |
r05 | | Kickers Offe | 1 - 4 | Rot-Weiss Es |
| 29 Jul 21 |
r03 | | Apoel Nicosi | 0 - 0 | Al Nassr FC |
| 29 Jul 21 |
r05 | | Salernitana | 1 - 0 | Fermana |
| 29 Jul 21 |
r05 | | Verona | 3 - 2 | Modena |
| 29 Jul 21 |
r05 | | Dalum | 4 - 1 | SfB-Oure |
| 29 Jul 21 |
r05 | | Staines Town | 0 - 6 | Maidenhead U |
| 29 Jul 21 |
r05 | | Villarreal | 0 - 0 | Levante |
| 29 Jul 21 |
r05 | | Millonarios | 2 - 3 | Atlético Na |
| 29 Jul 21 |
r05 | | Andorra | 2 - 0 | Villarreal B |
| 29 Jul 21 |
r03 | | Jong Utrecht | 1 - 3 | TOP Oss |
| 29 Jul 21 |
r03 | | Rödinghause | - | Jong Utrecht |
| 29 Jul 21 |
r05 | | Locomotive T | 2 - 0 | Sabail FK |
| 29 Jul 21 |
r05 | | Vitesse | - | Bochum |
| 29 Jul 21 |
r03 | | Bochum | 1 - 2 | Vitesse |
| 29 Jul 21 |
r03 | | Apoel Nicosi | - | Al Nasr |
| 29 Jul 21 |
r03 | | Fiorentina | 9 - 0 | US Levico Te |
| 29 Jul 21 |
r05 | | L.R. Vicenza | - | Virtus Veron |
| 29 Jul 21 |
r05 | | SSD Palermo | 1 - 0 | Monopoli |
| 29 Jul 21 |
r05 | | Algeciras CF | 2 - 3 | Al Shabab |
| 29 Jul 21 |
r01 | | Hertha | 4 - 3 | Liverpool |
| 30 Jul 21 |
r03 | | Las Palmas | 5 - 0 | UD San Ferna |
| 30 Jul 21 |
r05 | | Næstved BK | 5 - 3 | B.93 |
| 30 Jul 21 |
r05 | | Hyde United | 2 - 0 | Grimsby |
| 30 Jul 21 |
r05 | | L.R. Vicenza | 0 - 1 | Lecce |
| 30 Jul 21 |
r05 | | Brabrand IF | 1 - 0 | Skive IK |
| 30 Jul 21 |
r05 | | Haro Deporti | 2 - 1 | Racing Rioja |
| 30 Jul 21 |
r05 | | Frem | 0 - 2 | Roskilde |
| 30 Jul 21 |
r05 | | Cadiz | 0 - 2 | Espanol |
| 30 Jul 21 |
r05 | | Aris Limasso | 0 - 2 | Doxa Katokop |
| 30 Jul 21 |
r03 | | Jong AZ | - | Standard |
| 30 Jul 21 |
r03 | | FC Den Bosch | 0 - 1 | SV TEC |
| 30 Jul 21 |
r03 | | Parma Calcio | - | Giana Ermini |
| 30 Jul 21 |
r05 | | União de Le | 1 - 1 | Anadia |
| 30 Jul 21 |
r03 | | Straelen | 3 - 4 | Fortuna Sitt |
| 30 Jul 21 |
r03 | | FC Dordrecht | 0 - 0 | Fortuna Sitt |
| 30 Jul 21 |
r01 | | Dortmund | 3 - 0 | Bologna |
| 30 Jul 21 |
r05 | | Struga | 2 - 1 | Malisheva |
| 30 Jul 21 |
r05 | | Sampdoria | - | Spezia |
| 30 Jul 21 |
r03 | | Fiorentina | 4 - 0 | Virtus Veron |
| 30 Jul 21 |
r05 | | Torpedo Kuta | 3 - 1 | Shukura |
| 30 Jul 21 |
r05 | | Les Herbiers | 0 - 1 | SO Cholet |
| 30 Jul 21 |
r05 | | Hertha | 3 - 2 | Al Hilal |
| 30 Jul 21 |
r05 | | FC Villefran | 1 - 1 | Thonon Évia |
| 30 Jul 21 |
r05 | | Espanol | - | Cadiz |
| 30 Jul 21 |
r05 | | Rot Weiss Ah | 1 - 1 | Rot-Weiß Er |
| 30 Jul 21 |
r05 | | Concarneau | 0 - 1 | Vannes OC |
| 30 Jul 21 |
r05 | | Bremer SV | 3 - 3 | VfL Oldenbur |
| 30 Jul 21 |
r03 | | SC Heracles | 4 - 1 | RKC Waalwijk |
| 30 Jul 21 |
r03 | | FC Den Bosch | - | Helmond Spor |
| 30 Jul 21 |
r03 | | FC Eindhoven | 0 - 2 | Lierse Kempe |
| 30 Jul 21 |
r05 | | Creteil | 0 - 0 | Red Star |
| 30 Jul 21 |
r05 | | Laval | 1 - 0 | US Lusitanos |
| 30 Jul 21 |
r05 | | Valencia | - | Levante |
| 30 Jul 21 |
r05 | | Bourg-Peronn | 1 - 1 | Annecy |
| 30 Jul 21 |
r05 | | FC Chambly | 3 - 0 | FC Fleury 91 |
| 30 Jul 21 |
r03 | | NEC Nijmegen | 2 - 0 | OFI |
| 30 Jul 21 |
r05 | | Boulogne | 2 - 1 | FC Versaille |
| 30 Jul 21 |
r03 | | Zaragoza | 1 - 1 | Atromitos |
| 30 Jul 21 |
r03 | | Levante | 1 - 0 | Valencia |
| 30 Jul 21 |
r03 | | Valladolid | - | Osasuna |
| 30 Jul 21 |
r03 | | SSV Jeddeloh | 0 - 3 | Atlas Delmen |
| 30 Jul 21 |
r05 | | Yeclano | 1 - 1 | UCAM Murcia |
| 30 Jul 21 |
r03 | | SC Cambuur | - | FC Emmen |
| 30 Jul 21 |
r03 | | Fuenlabrada | 0 - 1 | Getafe |
| 30 Jul 21 |
r05 | | Sunderland | - | Hull |
| 30 Jul 21 |
r03 | | NAC Breda | 1 - 0 | Lommel SK |
| 30 Jul 21 |
r03 | | Hull | 2 - 1 | Sunderland |
| 30 Jul 21 |
r03 | | Rotherham | 0 - 1 | Middlesbroug |
| 30 Jul 21 |
r03 | | Carlisle | 3 - 0 | Halifax |
| 30 Jul 21 |
r03 | | Fleetwood To | 2 - 1 | Leeds |
| 30 Jul 21 |
r03 | | Bamber Bridg | - | Blackpool |
| 30 Jul 21 |
r03 | | Wigan | 3 - 2 | Preston |
| 30 Jul 21 |
r03 | | Knockbreda | 2 - 2 | Portadown |
| 30 Jul 21 |
r03 | | Aveley | 0 - 5 | Dagenham & R |
| 30 Jul 21 |
r05 | | Chippenham T | - | Taunton Town |
| 30 Jul 21 |
r03 | | Burton | 0 - 2 | Newcastle |
| 31 Jul 21 |
r05 | | Kustošija | 1 - 0 | Dubrava |
| 31 Jul 21 |
r05 | | Entella | 1 - 1 | Albinoleffe |
| 31 Jul 21 |
r05 | | Atalanta | 2 - 1 | Pordenone Ca |
| 31 Jul 21 |
r05 | | Frosinone | 2 - 0 | Ternana |
| 31 Jul 21 |
r05 | | Belasica | 1 - 1 | Borec |
| 31 Jul 21 |
r05 | | Besiktas | 0 - 3 | Kayserispor |
| 31 Jul 21 |
r05 | | Stuttgart | 0 - 3 | Barcelona |
| 31 Jul 21 |
r05 | | Wolfsburg | 1 - 2 | Ath Madrid |
| 31 Jul 21 |
r03 | | Troyes | - | Strasbourg |
| 31 Jul 21 |
r03 | | Jong AZ | - | St. Gilloise |
| 31 Jul 21 |
r01 | | Manchester C | 4 - 0 | Barnsley |
| 31 Jul 21 |
r03 | | Leganes | 0 - 1 | Real Madrid |
| 31 Jul 21 |
r05 | | Osasuna | 1 - 0 | Mirandes |
| 31 Jul 21 |
r05 | | Portstewart | 1 - 3 | Cliftonville |
| 31 Jul 21 |
r05 | | Ballinamalla | 3 - 0 | Warrenpoint |
| 31 Jul 21 |
r05 | | Coleraine | 5 - 0 | Dergview |
| 31 Jul 21 |
r05 | | Karmiotissa | 1 - 4 | Olympiakos N |
| 31 Jul 21 |
r05 | | Exeter | 0 - 2 | Shrewsbury |
| 31 Jul 21 |
r05 | | Fenerbahce | 3 - 2 | SPVGG Greuth |
| 31 Jul 21 |
r05 | | FC Utrecht | 2 - 3 | Venezia |
| 31 Jul 21 |
r03 | | Empoli | - | Montevarchi |
| 31 Jul 21 |
r03 | | Pro Patria | 0 - 1 | Alessandria |
| 31 Jul 21 |
r03 | | Strasbourg | 2 - 1 | Freiburg |
| 31 Jul 21 |
r03 | | Malaga | 1 - 1 | Almeria |
| 31 Jul 21 |
r03 | | Go Ahead Eag | 1 - 2 | FC Emmen |
| 31 Jul 21 |
r03 | | Troyes | 1 - 1 | Bordeaux |
| 31 Jul 21 |
r05 | | Como | 2 - 0 | Renate |
| 31 Jul 21 |
r05 | | Ascoli | 2 - 0 | Viterbese |
| 31 Jul 21 |
r05 | | Worksop Town | 0 - 0 | Gainsborough |
| 31 Jul 21 |
r03 | | Doxa Katokop | - | Aris Limasso |
| 31 Jul 21 |
r05 | | FC Porto | 5 - 3 | Lyon |
| 31 Jul 21 |
r05 | | Monza | 1 - 2 | Juventus |
| 31 Jul 21 |
r02 | | Alanyaspor | - | Karagumruk |
| 31 Jul 21 |
r01 | | Troyes | - | Manchester C |
| 31 Jul 21 |
r05 | | Reading | 1 - 3 | Crystal Pala |
| 31 Jul 21 |
r05 | | Cremonese | 2 - 1 | Feralpisalò |
| 31 Jul 21 |
r05 | | Ossett Unite | 1 - 0 | Grantham Tow |
| 31 Jul 21 |
r05 | | Nantes | 1 - 2 | Clermont Foo |
| 31 Jul 21 |
r03 | | Sutton Unite | 2 - 1 | Barnet |
| 31 Jul 21 |
r05 | | Hednesford T | 0 - 0 | Leamington |
| 31 Jul 21 |
r05 | | Havant & Wat | 3 - 1 | Gosport Boro |
| 31 Jul 21 |
r03 | | Tranmere | 1 - 2 | Burnley |
| 31 Jul 21 |
r05 | | Brackley Tow | 2 - 1 | Kettering To |
| 31 Jul 21 |
r05 | | Hamburg II | 2 - 3 | Aachen |
| 31 Jul 21 |
r05 | | FC Koln | 1 - 1 | Roda JC |
| 31 Jul 21 |
r05 | | Bochum | 0 - 2 | FC Utrecht |
| 31 Jul 21 |
r05 | | Giresunspor | 0 - 2 | Ümraniyespo |
| 31 Jul 21 |
r05 | | Lippstadt 08 | 1 - 3 | TSV Steinbac |
| 31 Jul 21 |
r05 | | Wingate & Fi | 0 - 2 | Chesham Unit |
| 31 Jul 21 |
r05 | | Sp Gijon B | 2 - 2 | Athletic Bil |
| 31 Jul 21 |
r05 | | AB Gladsaxe | 3 - 3 | Herlev |
| 31 Jul 21 |
r03 | | Leverkusen | 3 - 1 | Rot-Weiß Ob |
| 31 Jul 21 |
r05 | | Slagelse B&I | 3 - 2 | FA 2000 |
| 31 Jul 21 |
r05 | | Tudelano | 1 - 3 | UD Logroñé |
| 31 Jul 21 |
r03 | | Dungannon Sw | 4 - 1 | H and W Weld |
| 31 Jul 21 |
r03 | | VVV-Venlo | 2 - 2 | Panathinaiko |
| 31 Jul 21 |
r03 | | Tamworth | 0 - 5 | Wrexham |
| 31 Jul 21 |
r05 | | Cordoba | 0 - 1 | Linares Depo |
| 31 Jul 21 |
r05 | | Mačva Šaba | 1 - 0 | Radnički Sr |
| 31 Jul 21 |
r05 | | Weiche Flens | 1 - 1 | Kolding IF |
| 31 Jul 21 |
r05 | | Brentford | 0 - 1 | West Ham |
| 31 Jul 21 |
r05 | | Chesterfield | 0 - 1 | Port Vale |
| 31 Jul 21 |
r05 | | Eastbourne B | 2 - 3 | Lewes |
| 31 Jul 21 |
r03 | | Swindon | 0 - 1 | Peterboro |
| 31 Jul 21 |
r04 | | Atlético Sa | 0 - 1 | Xerez Deport |
| 31 Jul 21 |
r03 | | Crusaders | 3 - 1 | Loughgall |
| 31 Jul 21 |
r05 | | Cittadella | 0 - 0 | Trento |
| 31 Jul 21 |
r04 | | Valladolid P | 2 - 1 | Cristo Atlé |
| 31 Jul 21 |
r05 | | Extremadura | 1 - 1 | Sevilla Atle |
| 31 Jul 21 |
r05 | | CD Teruel | 0 - 0 | Atlético Le |
| 31 Jul 21 |
r05 | | Calahorra | 1 - 3 | SD Amorebiet |
| 31 Jul 21 |
r05 | | Real Unión | 2 - 2 | Santander |
| 31 Jul 21 |
r05 | | Numancia | 1 - 3 | Osasuna B |
| 31 Jul 21 |
r05 | | Sp Gijon | 1 - 0 | Ponferradina |
| 31 Jul 21 |
r05 | | Roma | 0 - 0 | Sevilla |
| 31 Jul 21 |
r05 | | SPAL 2013 | 6 - 0 | Pontedera |
| 31 Jul 21 |
r05 | | Sirens FC | 1 - 1 | Valletta |
| 31 Jul 21 |
r05 | | Lugo | 1 - 1 | Real Oviedo |
| 31 Jul 21 |
r05 | | Lens | 4 - 1 | Udinese |
| 31 Jul 21 |
r05 | | Leeds | 2 - 3 | Betis |
| 31 Jul 21 |
r05 | | Fortuna Köl | 4 - 2 | Schott Mainz |
| 31 Jul 21 |
r05 | | Hessen Kasse | 0 - 1 | VfV Hildeshe |
| 31 Jul 21 |
r05 | | Ein Frankfur | 2 - 1 | St Etienne |
| 31 Jul 21 |
r05 | | Malaga | 0 - 3 | Alcorcon |
| 31 Jul 21 |
r05 | | Getafe | 0 - 0 | Vallecano |
| 31 Jul 21 |
r05 | | Dinamo Zagre | 2 - 2 | Osijek II |
| 31 Jul 21 |
r05 | | Sabadell | 3 - 1 | L-'Hospitale |
| 31 Jul 21 |
r05 | | Al-Raed | 1 - 0 | CF Intercity |
| 31 Jul 21 |
r05 | | Peña Sport | 0 - 2 | SD Logroñé |
| 31 Jul 21 |
r05 | | Celta Vigo | 2 - 0 | Pafos FC |
| 31 Jul 21 |
r05 | | Genk | - | Waasland-Bev |
| 31 Jul 21 |
r05 | | Stuttgart II | - | Astoria Wall |
| 31 Jul 21 |
r03 | | Sutton Unite | - | Swindon |
| 31 Jul 21 |
r03 | | Sparta Nijke | - | Go Ahead Eag |
| 31 Jul 21 |
r03 | | Almere City | 0 - 1 | FC Groningen |
| 31 Jul 21 |
r03 | | Dover | 0 - 2 | Stevenage |
| 31 Jul 21 |
r03 | | Staines Town | - | Maidenhead U |
| 31 Jul 21 |
r03 | | SC Heracles | 2 - 2 | De Graafscha |
| 31 Jul 21 |
r03 | | Huddersfield | - | Crewe |
| 31 Jul 21 |
r03 | | Cardiff | 2 - 0 | Newport |
| 31 Jul 21 |
r03 | | Bristol City | 0 - 3 | Aston Villa |
| 31 Jul 21 |
r03 | | Bristol Rove | 3 - 2 | Oxford Utd |
| 31 Jul 21 |
r03 | | Stoke | 1 - 1 | Wolves |
| 31 Jul 21 |
r05 | | Wolves | - | Stoke |
| 31 Jul 21 |
r03 | | Westerlo | - | Panathinaiko |
| 31 Jul 21 |
r03 | | Rödinghause | - | Oldenburg |
| 31 Jul 21 |
r03 | | Schalke 04 I | 0 - 2 | Hannover II |
| 31 Jul 21 |
r03 | | Excelsior | 0 - 3 | Sparta |
| 31 Jul 21 |
r03 | | Ballymena Un | 0 - 2 | Institute |
| 31 Jul 21 |
r01 | | Preston | - | Manchester U |
| 31 Jul 21 |
r03 | | FC Volendam | 4 - 2 | Jong Ajax |
| 31 Jul 21 |
r03 | | Angers | 1 - 0 | Lorient |
| 31 Jul 21 |
r05 | | Stocksbridge | 1 - 2 | Spennymoor T |
| 31 Jul 21 |
r03 | | Brightlingse | 0 - 5 | Altrincham |
| 31 Jul 21 |
r03 | | Leyton Orien | 2 - 0 | Gillingham |
| 31 Jul 21 |
r03 | | Union Berlin | 2 - 1 | Ath Bilbao |
| 31 Jul 21 |
r03 | | Bielefeld | 1 - 1 | FC Twente |
| 31 Jul 21 |
r03 | | Augsburg | 3 - 1 | Cagliari |
| 31 Jul 21 |
r03 | | Hoffenheim | 3 - 1 | Stade de Rei |
| 31 Jul 21 |
r03 | | Mönchenglad | 2 - 1 | FC Groningen |
| 31 Jul 21 |
r00 | | Caernarfon T | - | AFC Telford |
| 31 Jul 21 |
r03 | | Alfreton Tow | 1 - 2 | Solihull Moo |
| 31 Jul 21 |
r03 | | QPR | 3 - 3 | Leicester |
| 31 Jul 21 |
r03 | | Accrington | 0 - 2 | Bradford |
| 31 Jul 21 |
r03 | | Torquay | 0 - 3 | Plymouth |
| 31 Jul 21 |
r03 | | Cambridge Un | 0 - 0 | Northampton |
| 31 Jul 21 |
r03 | | Sheffield Un | - | Norwich |
| 31 Jul 21 |
r03 | | Dartford | 2 - 2 | Southend |
| 31 Jul 21 |
r03 | | Wealdstone | 1 - 1 | Colchester |
| 31 Jul 21 |
r03 | | Yeovil | 0 - 1 | Forest Green |
| 31 Jul 21 |
r03 | | Portsmouth | 2 - 0 | Peterboro |
| 31 Jul 21 |
r03 | | Chester City | 3 - 0 | Fleetwood To |
| 31 Jul 21 |
r03 | | Ipswich | 0 - 3 | Millwall |
| 31 Jul 21 |
r03 | | Swansea | 1 - 3 | Southampton |
| 31 Jul 21 |
r03 | | Cheltenham | 2 - 0 | Walsall |
| 31 Jul 21 |
r03 | | Nottingham F | - | Burnley |
| 31 Jul 21 |
r03 | | Birmingham | 0 - 4 | West Brom |
| 31 Jul 21 |
r05 | | Ajax | 1 - 1 | RasenBallspo |
| 31 Jul 21 |
r03 | | Dorchester T | 2 - 5 | Weymouth |
| 31 Jul 21 |
r03 | | Salford City | 0 - 2 | Lincoln |
| 31 Jul 21 |
r05 | | Enfield Town | 1 - 7 | Hayes & Yead |
| 31 Jul 21 |
r03 | | Southport | 2 - 1 | Barrow |
| 31 Jul 21 |
r03 | | Stratford To | 0 - 2 | Kings Lynn T |
| 31 Jul 21 |
r03 | | Morecambe | 1 - 1 | Blackpool |
| 31 Jul 21 |
r02 | | Hertha | - | Gaziantep FK |
| 31 Jul 21 |
r05 | | Horsham | 2 - 1 | Metropolitan |
| 31 Jul 21 |
r05 | | Luton | 1 - 3 | Brighton |
| 31 Jul 21 |
r05 | | Leverkusen | - | Celta Vigo |
| 31 Jul 21 |
r05 | | Cray Valley | 1 - 1 | Welling Unit |
| 31 Jul 21 |
r01 | | RasenBallspo | 1 - 1 | Ajax |
| 31 Jul 21 |
r03 | | Bolton | 2 - 2 | Blackburn |
| 31 Jul 21 |
r03 | | AFC Wimbledo | 1 - 2 | Scunthorpe |
| 31 Jul 21 |
r05 | | Tamworth | - | Worcester |
| 31 Jul 21 |
r03 | | Hemel Hempst | 0 - 3 | Dagenham & R |
| 31 Jul 21 |
r03 | | Kings Langle | 0 - 5 | Boreham Wood |
| 31 Jul 21 |
r03 | | Banbridge To | 0 - 5 | Carrick Rang |
| 31 Jul 21 |
r03 | | Curzon | 0 - 4 | Stockport |
| 31 Jul 21 |
r03 | | Farnborough | 1 - 1 | Maidenhead U |
| 31 Jul 21 |
r01 | | Bayern Munic | 0 - 3 | Napoli |
| 31 Jul 21 |
r05 | | Voltigeurs d | 0 - 1 | Stade Brioch |
| 31 Jul 21 |
r05 | | Spezia | - | Calcio Monte |
| 31 Jul 21 |
r03 | | AZ Alkmaar | 1 - 0 | Sociedad |
| 31 Jul 21 |
r03 | | Watford | - | Barnsley |
| 31 Jul 21 |
r05 | | Watford | - | Nantes |
| 31 Jul 21 |
r03 | | Fulham | 1 - 0 | Charlton |
| 31 Jul 21 |
r05 | | Pevidém | 0 - 1 | União de Le |
| 31 Jul 21 |
r03 | | SPVGG Greuth | - | Eibar |
| 31 Jul 21 |
r03 | | Mainz | 3 - 2 | Genoa |
| 31 Jul 21 |
r03 | | Huddersfield | - | Oldham |
| 31 Jul 21 |
r05 | | Alessandria | 1 - 0 | Pro Patria |
| 31 Jul 21 |
r03 | | Rennes | 1 - 0 | Torino |
| 31 Jul 21 |
r03 | | MVV Maastric | - | Lommel SK |
| 31 Jul 21 |
r02 | | Kasimpasa | 1 - 2 | Istanbul Bas |
| 31 Jul 21 |
r03 | | Metz | 1 - 0 | Montpellier |
| 31 Jul 21 |
r03 | | Lommel SK | 1 - 2 | MVV Maastric |
| 31 Jul 21 |
r04 | | Cayón | - | Rayo Cantabr |
| 31 Jul 21 |
r03 | | PEC Zwolle | 0 - 2 | SC Heerenvee |
| 31 Jul 21 |
r03 | | Alaves | 0 - 1 | Elche |
| 31 Jul 21 |
r05 | | Apollon Smir | 1 - 3 | Ionikos |
| 31 Jul 21 |
r03 | | Real Socieda | 0 - 0 | Burgos |
| 31 Jul 21 |
r03 | | Tenerife | 0 - 0 | Cartagena FC |
| 31 Jul 21 |
r05 | | Guijuelo | 2 - 2 | Unionistas d |
| 31 Jul 21 |
r03 | | Go Ahead Eag | - | Willem II |
| 31 Jul 21 |
r05 | | CD Toledo | 0 - 1 | SS Reyes |
| 31 Jul 21 |
r05 | | Badajoz | 1 - 0 | Salamanca UD |
| 31 Jul 21 |
r05 | | Xerez | - | Marbella |
| 31 Jul 21 |
r01 | | Nice | 1 - 1 | Milan |
| 31 Jul 21 |
r03 | | Marseille | 2 - 1 | Villarreal |
| 01 Aug 21 |
r03 | | RKVV DEM | 1 - 1 | SC Telstar |
| 01 Aug 21 |
r05 | | Konyaspor | 1 - 0 | Antalyaspor |
| 01 Aug 21 |
r03 | | SSD Palermo | 1 - 2 | Salernitana |
| 01 Aug 21 |
r05 | | Goztepe | 3 - 1 | Nazilli Bele |
| 01 Aug 21 |
r03 | | Crotone | 1 - 0 | Giana Ermini |
| 01 Aug 21 |
r05 | | Lamia | 1 - 3 | Panetolikos |
| 01 Aug 21 |
r05 | | Perugia | 2 - 0 | Cesena |
| 01 Aug 21 |
r05 | | Parma Calcio | 0 - 3 | Sassuolo |
| 01 Aug 21 |
r05 | | Huesca | 1 - 0 | Castellón |
| 01 Aug 21 |
r03 | | Almere City | 1 - 1 | Westerlo |
| 01 Aug 21 |
r05 | | Cadiz | 1 - 2 | Almeria |
| 01 Aug 21 |
r05 | | Catanzaro | 1 - 1 | Vibonese |
| 01 Aug 21 |
r05 | | Bognor Regis | 1 - 3 | Dorking Wand |
| 01 Aug 21 |
r05 | | Harrogate To | 2 - 3 | Doncaster |
| 01 Aug 21 |
r05 | | Brescia | 1 - 0 | Mantova |
| 01 Aug 21 |
r05 | | Asteras Trip | 4 - 0 | Ionikos |
| 01 Aug 21 |
r04 | | Pergolettese | 3 - 2 | Piacenza |
| 01 Aug 21 |
r05 | | Lens | - | USL Dunkerqu |
| 01 Aug 21 |
r03 | | Coventry | 1 - 2 | Wolves |
| 01 Aug 21 |
r03 | | Derby | 0 - 2 | Notts County |
| 01 Aug 21 |
r05 | | Notts County | - | Derby |
| 01 Aug 21 |
r05 | | Wolves | 2 - 1 | Coventry |
| 01 Aug 21 |
r03 | | SC Telstar | 1 - 1 | RKVV DEM |
| 01 Aug 21 |
r03 | | Feyenoord | 1 - 1 | ADO Den Haag |
| 01 Aug 21 |
r03 | | Lüneburger | - | Holstein Kie |
| 01 Aug 21 |
r05 | | Almere City | - | FC Koln |
| 01 Aug 21 |
r01 | | Arsenal | 1 - 2 | Chelsea |
| 01 Aug 21 |
r05 | | Kaizer Chief | 1 - 0 | Orlando Pira |
| 01 Aug 21 |
r05 | | Giana Ermini | 0 - 1 | Crotone |
| 01 Aug 21 |
r05 | | Piacenza | 2 - 3 | Pergolettese |
| 01 Aug 21 |
r05 | | Alessandria | - | U.S.D. 1913 |
| 01 Aug 21 |
r05 | | Arda Kardzha | 2 - 1 | Al Nassr FC |
| 01 Aug 21 |
r05 | | Cittadella | - | Luparense F. |
| 01 Aug 21 |
r05 | | Salernitana | 2 - 1 | SSD Palermo |
| 01 Aug 21 |
r05 | | Bregalnica � | 3 - 0 | Sileks |
| 01 Aug 21 |
r03 | | Brest | 1 - 2 | Mallorca |
| 01 Aug 21 |
r05 | | Águilas | 1 - 2 | Al-Nasr Sala |
| 01 Aug 21 |
r05 | | Tenerife | 1 - 1 | Albacete |
| 01 Aug 21 |
r05 | | Llagostera | 0 - 2 | Girona |
| 02 Aug 21 |
r03 | | Granada | 3 - 0 | Linense |
| 02 Aug 21 |
r03 | | Standard | - | Molenbeek |
| 03 Aug 21 |
r05 | | Cray Valley | 3 - 2 | Leatherhead |
| 03 Aug 21 |
r05 | | Dulwich Haml | 2 - 2 | Bromley |
| 03 Aug 21 |
r05 | | Faversham To | 2 - 1 | Margate |
| 03 Aug 21 |
r05 | | Hungerford T | 3 - 2 | Swindon Supe |
| 03 Aug 21 |
r05 | | Hyde United | 2 - 0 | Curzon |
| 03 Aug 21 |
r03 | | Spezia | - | Trento |
| 03 Aug 21 |
r05 | | Witton | 1 - 2 | Marine |
| 03 Aug 21 |
r05 | | Brighouse To | 2 - 2 | Farsley Celt |
| 03 Aug 21 |
r05 | | Panetolikos | 0 - 1 | NFC Volos |
| 03 Aug 21 |
r05 | | Dundela | 1 - 3 | Glentoran |
| 03 Aug 21 |
r05 | | Warrington T | 1 - 2 | Southport |
| 03 Aug 21 |
r00 | | AFC Telford | 1 - 1 | Stafford Ran |
| 03 Aug 21 |
r05 | | Aveley | 2 - 4 | Lewes |
| 03 Aug 21 |
r05 | | FC Twente | 0 - 1 | Venezia |
| 03 Aug 21 |
r05 | | Antalyaspor | 0 - 1 | Altay |
| 03 Aug 21 |
r04 | | Sportlust 46 | 3 - 1 | Excelsior Ma |
| 03 Aug 21 |
r05 | | Manchester C | 4 - 1 | Blackpool |
| 03 Aug 21 |
r05 | | Fleetwood To | 0 - 4 | Wrexham |
| 03 Aug 21 |
r03 | | Armagh City | 0 - 4 | Dungannon Sw |
| 03 Aug 21 |
r05 | | Extremadura | 0 - 1 | Talavera |
| 03 Aug 21 |
r04 | | Lorca Deport | 2 - 1 | Mar Menor |
| 03 Aug 21 |
r05 | | SV TEC | 2 - 1 | GVVV |
| 03 Aug 21 |
r05 | | Institute | 0 - 3 | Cliftonville |
| 03 Aug 21 |
r02 | | Alanyaspor | 2 - 0 | Rizespor |
| 03 Aug 21 |
r05 | | Stockport | - | Lincoln |
| 03 Aug 21 |
r03 | | Peña Deport | 2 - 0 | UD Ibiza |
| 03 Aug 21 |
r05 | | Cibalia | 2 - 2 | Osijek II |
| 03 Aug 21 |
r02 | | Istanbul Bas | 2 - 2 | Hatayspor |
| 03 Aug 21 |
r05 | | Celta Vigo | 0 - 0 | Gil Vicente |
| 03 Aug 21 |
r05 | | NK Inter Zap | 2 - 1 | Dinamo Zagre |
| 03 Aug 21 |
r05 | | Hannoversche | 1 - 1 | Sportfreunde |
| 03 Aug 21 |
r05 | | Olot | 1 - 3 | Barcelona B |
| 03 Aug 21 |
r03 | | Elche | 1 - 1 | Cartagena FC |
| 03 Aug 21 |
r05 | | Unionistas d | 3 - 0 | Leganés II |
| 03 Aug 21 |
r05 | | Ossett Unite | 0 - 1 | York |
| 03 Aug 21 |
r03 | | Kings Lynn T | 1 - 0 | Peterboro |
| 03 Aug 21 |
r03 | | Truro City | 1 - 0 | Exeter |
| 03 Aug 21 |
r03 | | Chippenham T | 2 - 2 | Eastleigh |
| 03 Aug 21 |
r03 | | Taunton Town | 0 - 1 | Yeovil |
| 03 Aug 21 |
r03 | | Queens Unive | - | Carrick Rang |
| 03 Aug 21 |
r05 | | Stalybridge | - | Rochdale |
| 03 Aug 21 |
r05 | | St Albans Ci | 2 - 0 | Hendon |
| 03 Aug 21 |
r03 | | Tiverton Tow | 1 - 3 | Torquay |
| 03 Aug 21 |
r03 | | Farnborough | 2 - 1 | Woking |
| 03 Aug 21 |
r03 | | Bradford Par | 1 - 2 | Altrincham |
| 03 Aug 21 |
r03 | | Alfreton Tow | 0 - 1 | Grimsby |
| 03 Aug 21 |
r05 | | Tamworth | 3 - 1 | Birmingham |
| 03 Aug 21 |
r05 | | Cray Wandere | 2 - 2 | Welling Unit |
| 03 Aug 21 |
r03 | | Guiseley | 1 - 2 | Halifax |
| 03 Aug 21 |
r03 | | Norwich | 5 - 0 | Gillingham |
| 04 Aug 21 |
r05 | | SV Salzburg | 2 - 1 | Barcelona |
| 04 Aug 21 |
r05 | | Gimnastic | 4 - 1 | Atlético Le |
| 04 Aug 21 |
r05 | | Cordoba | 4 - 3 | Marbella |
| 04 Aug 21 |
r05 | | Zaragoza | 0 - 0 | Getafe |
| 04 Aug 21 |
r05 | | Valencia | 0 - 0 | Milan |
| 04 Aug 21 |
r05 | | Huesca | 1 - 0 | Mallorca |
| 04 Aug 21 |
r05 | | Fenerbahce | 1 - 1 | Dynamo Kiev |
| 04 Aug 21 |
r05 | | Valladolid | 3 - 1 | Vallecano |
| 04 Aug 21 |
r05 | | Cadiz | 1 - 1 | Ath Madrid |
| 04 Aug 21 |
r05 | | Southampton | 1 - 0 | Levante |
| 04 Aug 21 |
r05 | | Leicester | 3 - 2 | Villarreal |
| 04 Aug 21 |
r03 | | Mouscron-Per | 1 - 0 | Gent |
| 04 Aug 21 |
r03 | | Lazio | 1 - 1 | SV Meppen |
| 04 Aug 21 |
r03 | | Empoli | - | Carrarese |
| 04 Aug 21 |
r03 | | Frosinone | - | Avellino |
| 04 Aug 21 |
r04 | | Albacete | 0 - 1 | CF Intercity |
| 04 Aug 21 |
r03 | | Pro Patria | 1 - 1 | Monza |
| 04 Aug 21 |
r04 | | Tropezón | 1 - 2 | Barakaldo |
| 04 Aug 21 |
r04 | | Alcoyano | 3 - 0 | Eldense |
| 04 Aug 21 |
r04 | | Águilas | 0 - 0 | Linares Depo |
| 04 Aug 21 |
r04 | | Sabadell | 2 - 1 | CE Europa |
| 04 Aug 21 |
r05 | | Düren | 3 - 3 | Fortuna Köl |
| 04 Aug 21 |
r05 | | Wisla Krakow | 1 - 2 | Napoli |
| 04 Aug 21 |
r05 | | Cittadella | 2 - 0 | Virtus Veron |
| 04 Aug 21 |
r05 | | Lamia | 2 - 0 | Giannina |
| 04 Aug 21 |
r05 | | Belenenses | 1 - 3 | Roma |
| 04 Aug 21 |
r03 | | Zamora | 0 - 3 | Ponferradina |
| 04 Aug 21 |
r03 | | Almeria | 2 - 1 | Betis |
| 04 Aug 21 |
r05 | | Fortuna Düs | 0 - 1 | Mainz II |
| 04 Aug 21 |
r05 | | Asteras Trip | 4 - 0 | Apollon Smir |
| 04 Aug 21 |
r05 | | Calcio Padov | 2 - 2 | Pordenone Ca |
| 04 Aug 21 |
r05 | | Sp Gijon B | 3 - 2 | Marino |
| 04 Aug 21 |
r05 | | Cornellà | 1 - 0 | Villarreal B |
| 04 Aug 21 |
r05 | | UCAM Murcia | 3 - 0 | Racing Murci |
| 04 Aug 21 |
r05 | | Chester City | 0 - 0 | Bolton |
| 04 Aug 21 |
r05 | | SS Reyes | 0 - 1 | Alcorcon |
| 04 Aug 21 |
r05 | | Osasuna | 2 - 0 | UD Logroñé |
| 04 Aug 21 |
r05 | | Ajax | - | Leeds |
| 04 Aug 21 |
r05 | | Monza | 1 - 1 | Pro Patria |
| 04 Aug 21 |
r03 | | Doxa Katokop | 1 - 0 | PAEEK |
| 04 Aug 21 |
r03 | | Olbia | 0 - 3 | Cagliari |
| 04 Aug 21 |
r05 | | Aris Limasso | - | Karmiotissa |
| 04 Aug 21 |
r03 | | SD Amorebiet | 2 - 1 | Eibar |
| 04 Aug 21 |
r02 | | Kasimpasa | 5 - 1 | Karagumruk |
| 04 Aug 21 |
r05 | | Bergantiños | 2 - 1 | La Coruna |
| 04 Aug 21 |
r03 | | Leganes | 0 - 2 | Fuenlabrada |
| 04 Aug 21 |
r05 | | Betis | 1 - 2 | Almeria |
| 04 Aug 21 |
r03 | | SC Heracles | 7 - 0 | HSC 21 |
| 04 Aug 21 |
r05 | | Schwarz-Wei� | - | Rot-Weiss Es |
| 04 Aug 21 |
r05 | | Southend | 2 - 3 | Brentford |
| 04 Aug 21 |
r05 | | Zamora F.C. | 0 - 3 | Ponferradina |
| 04 Aug 21 |
r05 | | Laredo | - | CD Vitoria |
| 04 Aug 21 |
r01 | | Chelsea | 2 - 2 | Tottenham |
| 05 Aug 21 |
r05 | | East Thurroc | 1 - 3 | Maidstone |
| 05 Aug 21 |
r03 | | Las Palmas | 1 - 0 | Panadería P |
| 05 Aug 21 |
r04 | | Arosa | 0 - 1 | Racing Club |
| 05 Aug 21 |
r05 | | Grantham Tow | 2 - 3 | Kettering To |
| 05 Aug 21 |
r04 | | Real Oviedo | 0 - 1 | CD Toledo |
| 05 Aug 21 |
r05 | | Ethnikos Ach | 3 - 1 | Olympiakos N |
| 05 Aug 21 |
r05 | | Alessandria | 5 - 1 | Fossano Calc |
| 05 Aug 21 |
r05 | | Goztepe | 3 - 2 | Menemen Bele |
| 05 Aug 21 |
r05 | | Atlético Ba | 0 - 1 | Algeciras CF |
| 05 Aug 21 |
r05 | | Liverpool | 2 - 0 | Bologna |
| 05 Aug 21 |
r05 | | Gjilani | 2 - 0 | Malisheva |
| 05 Aug 21 |
r05 | | Tvååkers I | 0 - 0 | Varbergs BoI |
| 06 Aug 21 |
r05 | | Bradford Par | 0 - 3 | Scarborough |
| 06 Aug 21 |
r05 | | Panathinaiko | 2 - 2 | NK Lokomotiv |
| 06 Aug 21 |
r05 | | Granada | 3 - 1 | Malaga |
| 06 Aug 21 |
r05 | | Altay | 1 - 3 | Ümraniyespo |
| 06 Aug 21 |
r05 | | Adana Demirs | 1 - 1 | Besiktas |
| 06 Aug 21 |
r05 | | Apollon Lima | 1 - 1 | Doxa Katokop |
| 06 Aug 21 |
r05 | | FC Groningen | 0 - 0 | Venezia |
| 06 Aug 21 |
r05 | | Sociedad | 3 - 1 | Eibar |
| 06 Aug 21 |
r04 | | Xerez Deport | 1 - 1 | Sevilla Atle |
| 06 Aug 21 |
r05 | | Crotone | 1 - 1 | Vibonese |
| 06 Aug 21 |
r03 | | Mancha Real | 2 - 2 | Vélez |
| 06 Aug 21 |
r02 | | Istanbul Bas | 0 - 0 | Malatyaspor |
| 06 Aug 21 |
r05 | | Santander | 0 - 0 | Burgos |
| 06 Aug 21 |
r04 | | L-'Hospitale | 0 - 2 | FC Andorra |
| 06 Aug 21 |
r03 | | Sociedad | 1 - 3 | Osasuna |
| 06 Aug 21 |
r03 | | SPAL 2013 | 1 - 2 | Cremonese |
| 06 Aug 21 |
r03 | | Alaves | 4 - 3 | Al Nasr |
| 06 Aug 21 |
r05 | | Valladolid | 2 - 2 | SD Amorebiet |
| 06 Aug 21 |
r02 | | Erzurumspor | 0 - 2 | Antalyaspor |
| 06 Aug 21 |
r03 | | Udinese | 4 - 0 | A.S.D. Cjarl |
| 06 Aug 21 |
r05 | | Las Palmas | 3 - 0 | Tamaraceite |
| 06 Aug 21 |
r05 | | Levante | 0 - 1 | Alaves |
| 06 Aug 21 |
r05 | | Alaves | 4 - 3 | Al-Nasr Sala |
| 06 Aug 21 |
r05 | | Spezia | - | Cremonese |
| 06 Aug 21 |
r03 | | Alcorcon | 2 - 1 | UD Ibiza |
| 06 Aug 21 |
r05 | | Lippstadt 08 | 0 - 0 | KSV Baunatal |
| 06 Aug 21 |
r05 | | SPAL 2013 | - | Verona |
| 06 Aug 21 |
r02 | | Istanbul Bas | - | Panathinaiko |
| 06 Aug 21 |
r05 | | Mancha Real | 0 - 0 | Velez Mostar |
| 06 Aug 21 |
r05 | | L-'Hospitale | 0 - 0 | Andorra |
| 06 Aug 21 |
r05 | | Dover | 4 - 1 | Watford |
| 06 Aug 21 |
r05 | | Merstham | 0 - 0 | Dulwich Haml |
| 07 Aug 21 |
r05 | | FC Utrecht | 2 - 3 | Fortuna Sitt |
| 07 Aug 21 |
r05 | | Rot Weiss Ah | 3 - 0 | FC Gießen |
| 07 Aug 21 |
r05 | | Fortuna Köl | 1 - 3 | TSV Steinbac |
| 07 Aug 21 |
r05 | | Nantwich Tow | 3 - 2 | Chester City |
| 07 Aug 21 |
r05 | | Rot-Weiss Es | 4 - 4 | SC Verl |
| 07 Aug 21 |
r05 | | Stuttgart II | 3 - 1 | TSG Balingen |
| 07 Aug 21 |
r05 | | Burnley | 0 - 2 | Cadiz |
| 07 Aug 21 |
r05 | | Dungannon Sw | 3 - 1 | Moyola Park |
| 07 Aug 21 |
r05 | | Cirencester | 3 - 2 | Didcot Town |
| 07 Aug 21 |
r05 | | Hungerford T | 1 - 1 | Gosport Boro |
| 07 Aug 21 |
r05 | | Mossley | 0 - 3 | Stalybridge |
| 07 Aug 21 |
r05 | | Southampton | 1 - 3 | Ath Bilbao |
| 07 Aug 21 |
r05 | | Swindon Supe | 0 - 0 | Banbury |
| 07 Aug 21 |
r05 | | Tobermore Un | 1 - 4 | Ballymena Un |
| 07 Aug 21 |
r05 | | West Ham | 2 - 0 | Atalanta |
| 07 Aug 21 |
r05 | | PAEEK | 1 - 1 | Olympiakos N |
| 07 Aug 21 |
r05 | | Giresunspor | 0 - 0 | Samsunspor |
| 07 Aug 21 |
r05 | | Udinese | 1 - 0 | Empoli |
| 07 Aug 21 |
r05 | | Brentford | 2 - 1 | Valencia |
| 07 Aug 21 |
r05 | | Frosinone | 2 - 2 | Benevento |
| 07 Aug 21 |
r05 | | Sampdoria | 1 - 0 | Verona |
| 07 Aug 21 |
r05 | | Brighton | 0 - 2 | Getafe |
| 07 Aug 21 |
r05 | | Goztepe | 2 - 0 | Altınordu |
| 07 Aug 21 |
r05 | | Elche | 1 - 2 | Levante |
| 07 Aug 21 |
r05 | | Sassuolo | 3 - 1 | L.R. Vicenza |
| 07 Aug 21 |
r03 | | Wiedenbrück | 0 - 0 | Hessen Kasse |
| 07 Aug 21 |
r03 | | Chesterfield | 3 - 1 | Tamworth |
| 07 Aug 21 |
r03 | | Glenavon | 2 - 0 | Portstewart |
| 07 Aug 21 |
r03 | | Crusaders | 4 - 0 | Bangor |
| 07 Aug 21 |
r03 | | Granada | - | Crotone |
| 07 Aug 21 |
r03 | | Pisa | - | U.S. Fiorenz |
| 07 Aug 21 |
r03 | | Fiorentina | 0 - 0 | Espanol |
| 07 Aug 21 |
r03 | | Ponferradina | 1 - 0 | Real Oviedo |
| 07 Aug 21 |
r03 | | Leganes | 1 - 1 | Vallecano |
| 07 Aug 21 |
r03 | | Leeds | 2 - 2 | Villarreal |
| 07 Aug 21 |
r03 | | Gimnastic | 2 - 1 | Girona |
| 07 Aug 21 |
r04 | | Gimnástica | 4 - 1 | Zamora |
| 07 Aug 21 |
r04 | | Farsley Celt | - | Hyde United |
| 07 Aug 21 |
r04 | | Onisilos | 1 - 5 | Nea Salamis |
| 07 Aug 21 |
r04 | | Dubrava | 3 - 0 | Opatija |
| 07 Aug 21 |
r04 | | Langreo | 1 - 1 | Leonesa |
| 07 Aug 21 |
r04 | | Albacete | 1 - 1 | Talavera |
| 07 Aug 21 |
r04 | | Real Titáni | 1 - 2 | UD Llanera |
| 07 Aug 21 |
r04 | | Recreativo | 1 - 0 | Cordoba |
| 07 Aug 21 |
r04 | | CD Teruel | 1 - 1 | Castellón |
| 07 Aug 21 |
r04 | | Cacereño | 2 - 1 | Guijuelo |
| 07 Aug 21 |
r04 | | Atlético Sa | - | Extremadura |
| 07 Aug 21 |
r04 | | Espanyol B | 1 - 4 | FC Andorra |
| 07 Aug 21 |
r04 | | Xerez | 0 - 0 | San Fernando |
| 07 Aug 21 |
r04 | | União de Le | 1 - 1 | Braga B |
| 07 Aug 21 |
r04 | | UCAM Murcia | 5 - 0 | Mar Menor |
| 07 Aug 21 |
r04 | | Rayo Cantabr | 0 - 0 | Barakaldo |
| 07 Aug 21 |
r04 | | Real Oviedo | 1 - 1 | Real Avilés |
| 07 Aug 21 |
r04 | | Burgos Prome | 1 - 1 | Cristo Atlé |
| 07 Aug 21 |
r04 | | Arenteiro | 3 - 0 | Celta Vigo B |
| 07 Aug 21 |
r05 | | Waasland-Bev | 2 - 2 | SC Cambuur |
| 07 Aug 21 |
r05 | | Brackley Tow | 1 - 0 | Oxford City |
| 07 Aug 21 |
r05 | | Ossett Unite | 1 - 2 | Matlock |
| 07 Aug 21 |
r05 | | Spennymoor T | 2 - 2 | Wrexham |
| 07 Aug 21 |
r05 | | Welling Unit | 1 - 2 | Bromley |
| 07 Aug 21 |
r05 | | RKC Waalwijk | 4 - 2 | Lommel SK |
| 07 Aug 21 |
r05 | | FC Twente | 0 - 1 | Lazio |
| 07 Aug 21 |
r05 | | Sesvete | 2 - 0 | Dinamo Zagre |
| 07 Aug 21 |
r05 | | FC Minsk | 0 - 2 | Isloch Minsk |
| 07 Aug 21 |
r05 | | Numancia | 2 - 0 | Rayo Majadah |
| 07 Aug 21 |
r05 | | VV DOVO | 3 - 1 | IJsselmeervo |
| 07 Aug 21 |
r04 | | Excelsior Ma | 4 - 0 | RKVV Westlan |
| 07 Aug 21 |
r03 | | Leganes | 2 - 0 | Alcorcon |
| 07 Aug 21 |
r05 | | Gimnástica | 4 - 1 | Zamora F.C. |
| 07 Aug 21 |
r03 | | Wolves | 0 - 1 | Celta Vigo |
| 07 Aug 21 |
r01 | | Manchester U | 4 - 0 | Everton |
| 07 Aug 21 |
r03 | | Willem II | - | Sparta |
| 07 Aug 21 |
r05 | | Aachen | 0 - 1 | FSV Frankfur |
| 07 Aug 21 |
r03 | | Wiedenbrück | 2 - 0 | Hannover II |
| 07 Aug 21 |
r03 | | Club Brugge | 2 - 1 | Westerlo |
| 07 Aug 21 |
r03 | | Alfreton Tow | 4 - 1 | Kings Lynn T |
| 07 Aug 21 |
r05 | | Atlas Delmen | 0 - 0 | Altona 93 |
| 07 Aug 21 |
r03 | | Newcastle | 3 - 0 | Norwich |
| 07 Aug 21 |
r03 | | Oldenburg | 3 - 4 | VfB Homberg |
| 07 Aug 21 |
r03 | | Schwarz-Wei� | - | Teutonia Ott |
| 07 Aug 21 |
r00 | | AFC Telford | - | Stoke |
| 07 Aug 21 |
r05 | | Lewes | 2 - 1 | Dartford |
| 07 Aug 21 |
r05 | | Potters Bar | 0 - 1 | Beaconsfield |
| 07 Aug 21 |
r05 | | Wingate & Fi | 2 - 3 | Harrow Borou |
| 07 Aug 21 |
r03 | | Aston Villa | - | Sevilla |
| 07 Aug 21 |
r05 | | Watford | - | Udinese |
| 07 Aug 21 |
r03 | | Wimborne Tow | 0 - 2 | Weymouth |
| 07 Aug 21 |
r03 | | Torquay | 3 - 0 | Chippenham T |
| 07 Aug 21 |
r03 | | Crystal Pala | 3 - 1 | Watford |
| 07 Aug 21 |
r03 | | Billericay | 3 - 2 | Dagenham & R |
| 07 Aug 21 |
r05 | | Stafford Ran | 1 - 1 | St Ives Town |
| 07 Aug 21 |
r03 | | Guiseley | 0 - 5 | Stockport |
| 07 Aug 21 |
r03 | | Slough Town | 1 - 2 | Aldershot |
| 07 Aug 21 |
r03 | | Dollingstown | 0 - 2 | Portadown |
| 07 Aug 21 |
r05 | | Bamber Bridg | - | City of Live |
| 07 Aug 21 |
r03 | | Leamington | 0 - 2 | Solihull Moo |
| 07 Aug 21 |
r03 | | Dorking Wand | 1 - 2 | Wealdstone |
| 07 Aug 21 |
r03 | | Ebbsfleet Un | 1 - 1 | Southend |
| 07 Aug 21 |
r05 | | Crusaders | - | Banbridge To |
| 07 Aug 21 |
r03 | | Tonbridge An | 0 - 4 | Dover |
| 07 Aug 21 |
r05 | | Folkestone I | 3 - 1 | Maidstone |
| 07 Aug 21 |
r05 | | Hereford | 1 - 2 | Bath City |
| 07 Aug 21 |
r05 | | Tamworth | 1 - 3 | Chesterfield |
| 07 Aug 21 |
r03 | | AFC Fylde | - | Halifax |
| 07 Aug 21 |
r03 | | Salisbury | 1 - 2 | Eastleigh |
| 07 Aug 21 |
r03 | | Curzon | 1 - 1 | Altrincham |
| 07 Aug 21 |
r03 | | Weston-super | 1 - 1 | Yeovil |
| 07 Aug 21 |
r05 | | Warrington T | 2 - 1 | Chorley |
| 07 Aug 21 |
r03 | | Boston Unite | 0 - 1 | Grimsby |
| 07 Aug 21 |
r03 | | Hemel Hempst | - | Boreham Wood |
| 07 Aug 21 |
r03 | | Hampton & Ri | 1 - 1 | Woking |
| 07 Aug 21 |
r03 | | Notts County | 2 - 3 | York |
| 07 Aug 21 |
r03 | | SC Heracles | 3 - 1 | PEC Zwolle |
| 07 Aug 21 |
r04 | | Needham Mark | - | AFC Sudbury |
| 07 Aug 21 |
r03 | | Apoel Nicosi | 1 - 1 | AEK Larnaca |
| 07 Aug 21 |
r05 | | Brescia | - | Reggio Audac |
| 07 Aug 21 |
r05 | | SC Heerenvee | - | Lecce |
| 07 Aug 21 |
r03 | | Lierse Kempe | 1 - 0 | Dender |
| 07 Aug 21 |
r05 | | Sabadell | 0 - 1 | Villarreal B |
| 07 Aug 21 |
r05 | | Granada | 2 - 1 | Linares Depo |
| 07 Aug 21 |
r05 | | Ankaragucu | 0 - 0 | Genclerbirli |
| 07 Aug 21 |
r03 | | Go Ahead Eag | - | Rödinghause |
| 07 Aug 21 |
r03 | | Real Socieda | 1 - 1 | Mirandes |
| 07 Aug 21 |
r03 | | Real Madrid | 0 - 1 | Fuenlabrada |
| 07 Aug 21 |
r05 | | Villarreal | - | Leeds |
| 07 Aug 21 |
r05 | | Pisa | - | Modena |
| 07 Aug 21 |
r03 | | Mallorca | 1 - 0 | Cagliari |
| 07 Aug 21 |
r01 | | Betis | 5 - 2 | Roma |
| 08 Aug 21 |
r05 | | Lamia | 3 - 0 | Ionikos |
| 08 Aug 21 |
r05 | | Panetolikos | 0 - 0 | Giannina |
| 08 Aug 21 |
r03 | | Napoli | 2 - 1 | Ascoli |
| 08 Aug 21 |
r04 | | Pontevedra | 1 - 3 | Racing Club |
| 08 Aug 21 |
r04 | | Linense | 1 - 1 | Atlético Ba |
| 08 Aug 21 |
r05 | | AZ Alkmaar | 2 - 1 | Torino |
| 08 Aug 21 |
r03 | | Almeria | 1 - 0 | Betis Deport |
| 08 Aug 21 |
r03 | | Aston Villa | 3 - 1 | Salernitana |
| 08 Aug 21 |
r03 | | Monza | 3 - 0 | Giana Ermini |
| 08 Aug 21 |
r01 | | Tottenham | 1 - 0 | Arsenal |
| 08 Aug 21 |
r05 | | Feyenoord | 2 - 1 | Ath Madrid |
| 08 Aug 21 |
r05 | | Liverpool | 1 - 1 | Ath Bilbao |
| 08 Aug 21 |
r02 | | Hatayspor | 1 - 0 | Gaziantep FK |
| 08 Aug 21 |
r03 | | Ethnikos Ach | 0 - 0 | AEK Larnaca |
| 08 Aug 21 |
r01 | | Real Madrid | 0 - 0 | Milan |
| 08 Aug 21 |
r05 | | Parma Calcio | 0 - 2 | Inter |
| 08 Aug 21 |
r02 | | Alanyaspor | 1 - 3 | Konyaspor |
| 08 Aug 21 |
r03 | | La Coruna | 1 - 2 | Ponferradina |
| 08 Aug 21 |
r05 | | Bologna | 4 - 2 | Pordenone Ca |
| 08 Aug 21 |
r05 | | Barcelona | 3 - 0 | Juventus |
| 09 Aug 21 |
r01 | | Giresunspor | 1 - 3 | Fenerbahce |
| 09 Aug 21 |
r05 | | Liverpool | 3 - 1 | Osasuna |
| 09 Aug 21 |
r03 | | Cliftonville | 1 - 2 | Derry City |
| 09 Aug 21 |
r03 | | UCD | 4 - 1 | Warrenpoint |
| 10 Aug 21 |
r04 | | VV Katwijk | 2 - 0 | Sparta Nijke |
| 10 Aug 21 |
r04 | | Al-Arabi | 3 - 2 | AD Ceuta FC |
| 10 Aug 21 |
r04 | | GVVV | 2 - 3 | SV OSS 20 |
| 10 Aug 21 |
r04 | | VV Staphorst | 1 - 3 | HHC Hardenbe |
| 10 Aug 21 |
r04 | | Real Calepin | 1 - 1 | Albinoleffe |
| 10 Aug 21 |
r03 | | Apollon Lima | 1 - 2 | Aris Limasso |
| 10 Aug 21 |
r03 | | SPAL 2013 | 5 - 0 | U.S. Adriese |
| 10 Aug 21 |
r03 | | Willem II | 2 - 1 | Virton |
| 10 Aug 21 |
r03 | | Aris | 0 - 0 | AE Larissa |
| 10 Aug 21 |
r03 | | Dollingstown | 0 - 6 | Glenavon |
| 10 Aug 21 |
r03 | | Panathinaiko | 1 - 1 | Apoel Nicosi |
| 10 Aug 21 |
r05 | | Tamworth | - | Notts County |
| 10 Aug 21 |
r03 | | Harrow Borou | 0 - 4 | Barnet |
| 10 Aug 21 |
r03 | | Carrick Rang | 3 - 0 | Lisburn Dist |
| 10 Aug 21 |
r05 | | Carrick Rang | - | PSNI |
| 10 Aug 21 |
r03 | | East Thurroc | - | Dagenham & R |
| 10 Aug 21 |
r03 | | Cartagena FC | 2 - 0 | Murcia |
| 11 Aug 21 |
r04 | | Entella | - | SC Ligorna 1 |
| 11 Aug 21 |
r03 | | Apoel Nicosi | - | Olympiakos N |
| 11 Aug 21 |
r03 | | Atalanta | 7 - 1 | Alessandria |
| 11 Aug 21 |
r03 | | Doxa Katokop | 1 - 3 | Alki Oroklin |
| 11 Aug 21 |
r03 | | Pafos FC | 2 - 0 | Akritas Chlo |
| 11 Aug 21 |
r04 | | S.C. Caronne | 1 - 2 | Pro Patria |
| 11 Aug 21 |
r04 | | Rayo Cantabr | 0 - 1 | Basconia |
| 11 Aug 21 |
r03 | | Vibonese | 0 - 2 | Reggina |
| 11 Aug 21 |
r04 | | Real Unión | 0 - 2 | Athletic Bil |
| 11 Aug 21 |
r03 | | FC Trenkwald | 1 - 5 | Al-Duhail SC |
| 11 Aug 21 |
r04 | | Real Titáni | 1 - 2 | Langreo |
| 11 Aug 21 |
r04 | | Albacete | 1 - 1 | UCAM Murcia |
| 11 Aug 21 |
r04 | | Cristo Atlé | 0 - 4 | Santander |
| 11 Aug 21 |
r04 | | Alcoyano | 2 - 1 | CF Intercity |
| 11 Aug 21 |
r04 | | Valladolid P | 2 - 2 | Burgos Prome |
| 11 Aug 21 |
r04 | | Arenteiro | 1 - 1 | Coruxo |
| 11 Aug 21 |
r04 | | Algeciras CF | 0 - 1 | Cordoba |
| 11 Aug 21 |
r04 | | Marino | 0 - 0 | Real Oviedo |
| 11 Aug 21 |
r03 | | Hitchin Town | 2 - 1 | Boreham Wood |
| 11 Aug 21 |
r04 | | Villarrubia | 2 - 0 | Calvo Sotelo |
| 12 Aug 21 |
r04 | | Don Benito | - | Extremadura |
| 12 Aug 21 |
r04 | | Valladolid P | 2 - 2 | Sp Gijon B |
| 13 Aug 21 |
r03 | | Lamia | - | NFC Volos |
| 13 Aug 21 |
r04 | | Teramo | 2 - 1 | Castelnuovo |
| 13 Aug 21 |
r03 | | Juventus U23 | 1 - 1 | Como |
| 13 Aug 21 |
r04 | | Pergolettese | 1 - 5 | Feralpisalò |
| 13 Aug 21 |
r03 | | PAEEK | - | Karmiotissa |
| 13 Aug 21 |
r04 | | Albinoleffe | 0 - 1 | Triestina |
| 13 Aug 21 |
r04 | | Ayia Napa | 0 - 5 | Nea Salamis |
| 13 Aug 21 |
r04 | | Cesena | 1 - 2 | Mantova |
| 13 Aug 21 |
r03 | | AEK Larnaca | 3 - 3 | Olympiakos N |
| 13 Aug 21 |
r04 | | Zamora | 2 - 1 | Salamanca UD |
| 13 Aug 21 |
r04 | | Badajoz | 1 - 1 | Sevilla Atle |
| 13 Aug 21 |
r04 | | Cordoba | 3 - 2 | Rayo Majadah |
| 14 Aug 21 |
r03 | | Ethnikos Ach | 5 - 2 | Doxa Katokop |
| 14 Aug 21 |
r04 | | Pontevedra | - | Coruxo |
| 14 Aug 21 |
r04 | | Mérida AD | - | Extremadura |
| 14 Aug 21 |
r03 | | Napoli | 4 - 0 | Pescara |
| 14 Aug 21 |
r04 | | Mérida AD | 0 - 0 | CD Coria |
| 14 Aug 21 |
r04 | | Gimnástica | 1 - 0 | Laredo |
| 14 Aug 21 |
r04 | | UCAM Murcia | 2 - 2 | Hercules |
| 14 Aug 21 |
r04 | | UD Llanera | 1 - 4 | Sp Gijon B |
| 14 Aug 21 |
r04 | | Numancia | 5 - 0 | Mutilvera |
| 14 Aug 21 |
r03 | | Moyola Park | 0 - 1 | Ballymena Un |
| 14 Aug 21 |
r03 | | Galway Unite | 1 - 3 | Warrenpoint |
| 14 Aug 21 |
r03 | | Chesterfield | 2 - 1 | Grimsby |
| 14 Aug 21 |
r03 | | Glentoran | 0 - 1 | Coleraine |
| 14 Aug 21 |
r03 | | Carrick Rang | 4 - 1 | Crusaders |
| 14 Aug 21 |
r03 | | Wealdstone | 3 - 1 | Hungerford T |
| 14 Aug 21 |
r03 | | Solihull Moo | 2 - 2 | Notts County |
| 14 Aug 21 |
r04 | | Enosis Neon | 1 - 1 | Anagennisi D |
| 14 Aug 21 |
r04 | | Athletic Bil | 2 - 1 | Santander |
| 14 Aug 21 |
r03 | | Apoel Nicosi | 2 - 0 | Apollon Lima |
| 14 Aug 21 |
r03 | | Asteras Trip | 1 - 0 | Giannina |
| 14 Aug 21 |
r03 | | Apoel Nicosi | - | Pafos FC |
| 14 Aug 21 |
r04 | | Entella | - | U.S.D. Real |
| 14 Aug 21 |
r03 | | Doxa Katokop | 5 - 2 | Ethnikos Ach |
| 14 Aug 21 |
r00 | | Inter | 3 - 0 | Dynamo Kiev |
| 14 Aug 21 |
r03 | | Ionikos | 1 - 1 | Atromitos |
| 14 Aug 21 |
r04 | | CE Europa | 1 - 2 | Espanyol B |
| 14 Aug 21 |
r03 | | Lazio | 1 - 1 | Sassuolo |
| 14 Aug 21 |
r03 | | Pafos FC | 1 - 1 | Aris Limasso |
| 14 Aug 21 |
r04 | | Linense | 2 - 1 | El Ejido |
| 14 Aug 21 |
r04 | | Gimnástica | 1 - 2 | Unionistas d |
| 14 Aug 21 |
r04 | | CF Badalona | 2 - 0 | Cornellà |
| 14 Aug 21 |
r03 | | Aris | 4 - 3 | NFC Volos |
| 14 Aug 21 |
r04 | | CD Teruel | 1 - 1 | Valencia Mes |
| 14 Aug 21 |
r03 | | AEK | 1 - 0 | Lamia |
| 14 Aug 21 |
r04 | | L-'Hospitale | 1 - 1 | AE Prat |
| 14 Aug 21 |
r04 | | Calvo Sotelo | 0 - 0 | CD Marchamal |
| 14 Aug 21 |
r00 | | Juventus | 3 - 1 | Atalanta |
| 14 Aug 21 |
r00 | | Milan | 2 - 1 | Panathinaiko |
| 14 Aug 21 |
r04 | | Albacete | 1 - 0 | Castellón |
| 14 Aug 21 |
r00 | | Roma | 5 - 0 | Raja Casabla |
| 15 Aug 21 |
r04 | | San Roque Le | 1 - 1 | Recreativo |
| 15 Aug 21 |
r04 | | Águilas | 0 - 0 | Lorca Deport |
| 15 Aug 21 |
r04 | | Móstoles CF | 0 - 0 | Mar Menor |
| 15 Aug 21 |
r05 | | La Coruna | 0 - 0 | Real Madrid |
| 15 Aug 21 |
r04 | | Vélez | 1 - 1 | Cacereño |
| 15 Aug 21 |
r05 | | CD Móstoles | 0 - 0 | Mar Menor |
| 15 Aug 21 |
r05 | | Andorra | 2 - 0 | Atlètic d'E |
| 15 Aug 21 |
r05 | | Weymouth | 0 - 13 | Chelsea |
| 15 Aug 21 |
r05 | | US Monastir | 4 - 1 | Hammam-Souss |
| 16 Aug 21 |
r05 | | Leganes | 3 - 0 | SS Reyes |
| 16 Aug 21 |
r03 | | Club Brugge | 7 - 2 | KMSK Deinze |
| 16 Aug 21 |
r04 | | Bergantiños | - | Coruxo |
| 17 Aug 21 |
r05 | | KF Vllaznia | 1 - 0 | Tërbuni Puk |
| 17 Aug 21 |
r05 | | Sevilla Atle | 4 - 0 | AD Ceuta FC |
| 17 Aug 21 |
r05 | | Villarrobled | 1 - 0 | Socuéllamos |
| 17 Aug 21 |
r03 | | Cliftonville | 1 - 0 | Dungannon Sw |
| 17 Aug 21 |
r03 | | Coleraine | 0 - 1 | Portadown |
| 17 Aug 21 |
r03 | | Glentoran | 4 - 0 | Warrenpoint |
| 17 Aug 21 |
r03 | | Carrick Rang | 3 - 0 | Ballyclare C |
| 18 Aug 21 |
r05 | | Forli | 2 - 2 | Cesena |
| 18 Aug 21 |
r04 | | Sangiuliano | 2 - 2 | Giana Ermini |
| 18 Aug 21 |
r04 | | Murcia | 0 - 1 | Hercules |
| 18 Aug 21 |
r04 | | CD Coria | 1 - 1 | Salamanca UD |
| 18 Aug 21 |
r04 | | Langreo | 0 - 2 | Unionistas d |
| 18 Aug 21 |
r04 | | Real Oviedo | 0 - 1 | Ceares |
| 18 Aug 21 |
r05 | | Leonesa | 1 - 1 | UD Llanera |
| 18 Aug 21 |
r04 | | Águilas | 1 - 2 | Almeria B |
| 18 Aug 21 |
r05 | | Gimnástica | 1 - 1 | Las Rozas CF |
| 18 Aug 21 |
r05 | | Espanyol B | 2 - 3 | Cornellà |
| 18 Aug 21 |
r05 | | Achyronas Li | 2 - 4 | Alki Oroklin |
| 18 Aug 21 |
r05 | | Real Madrid | 1 - 1 | Badajoz |
| 18 Aug 21 |
r05 | | UCAM Murcia | 1 - 0 | El Ejido |
| 18 Aug 21 |
r05 | | CD Varea | 0 - 5 | Alavés B |
| 19 Aug 21 |
r05 | | Real Calepin | 0 - 1 | Olginatese |
| 19 Aug 21 |
r05 | | Socuéllamos | 1 - 1 | Villarrubia |
| 19 Aug 21 |
r05 | | Cordoba | 1 - 0 | Extremadura |
| 19 Aug 21 |
r04 | | Cristo Atlé | 3 - 1 | Zamora |
| 19 Aug 21 |
r05 | | Qadsia SC | 1 - 1 | Al-Markhiya |
| 20 Aug 21 |
r04 | | Ardoi | - | Real Unión |
| 20 Aug 21 |
r04 | | Burgos Prome | 3 - 1 | Zamora |
| 20 Aug 21 |
r04 | | Calvo Sotelo | 0 - 0 | Linares Depo |
| 20 Aug 21 |
r04 | | Arenteiro | 1 - 1 | La Coruna |
| 20 Aug 21 |
r04 | | Leganés II | 1 - 1 | Atlético Ma |
| 20 Aug 21 |
r04 | | Lleida Espor | 2 - 1 | FC Andorra |
| 20 Aug 21 |
r04 | | Real Avilés | 0 - 4 | Leonesa |
| 20 Aug 21 |
r05 | | ASIL | 0 - 0 | Nea Salamis |
| 20 Aug 21 |
r05 | | Real Unión | 0 - 1 | CD Izarra |
| 20 Aug 21 |
r04 | | Xerez Deport | 0 - 2 | Betis Deport |
| 20 Aug 21 |
r05 | | AEL Limassol | 0 - 0 | PAEEK |
| 20 Aug 21 |
r03 | | Cliftonville | 3 - 0 | Portadown |
| 20 Aug 21 |
r05 | | Burgos Prome | 3 - 1 | Zamora F.C. |
| 20 Aug 21 |
r05 | | Alzira | 1 - 0 | Castellón |
| 20 Aug 21 |
r05 | | El Ejido | 2 - 1 | Recreativo G |
| 21 Aug 21 |
r05 | | Calahorra | 2 - 0 | Ebro |
| 21 Aug 21 |
r05 | | Santander | 2 - 2 | Numancia |
| 21 Aug 21 |
r05 | | Alki Oroklin | 5 - 1 | ASIL |
| 21 Aug 21 |
r04 | | Xerez Deport | 2 - 1 | San Fernando |
| 21 Aug 21 |
r05 | | La Coruna | 3 - 2 | Pontevedra |
| 21 Aug 21 |
r05 | | UD Llanera | 3 - 0 | Real Oviedo |
| 21 Aug 21 |
r05 | | Belasica | 1 - 2 | Vardar |
| 21 Aug 21 |
r04 | | Linense | 2 - 0 | Cordoba |
| 21 Aug 21 |
r05 | | Panathinaiko | 1 - 2 | Panetolikos |
| 21 Aug 21 |
r03 | | Aris | 4 - 1 | Giannina |
| 21 Aug 21 |
r04 | | Águilas | 1 - 1 | UCAM Murcia |
| 21 Aug 21 |
r05 | | Real Madrid | 1 - 0 | Athletic Bil |
| 21 Aug 21 |
r03 | | Dollingstown | - | Coleraine |
| 21 Aug 21 |
r05 | | U.S. Folgore | 1 - 2 | USD Casatese |
| 21 Aug 21 |
r03 | | Glentoran | 3 - 1 | Crusaders |
| 21 Aug 21 |
r05 | | Apollon Smir | 1 - 2 | OFI |
| 21 Aug 21 |
r05 | | Akritas Chlo | 0 - 4 | Nea Salamis |
| 21 Aug 21 |
r05 | | Atromitos | 1 - 1 | Lamia |
| 21 Aug 21 |
r05 | | Olot | 0 - 1 | Gimnastic |
| 21 Aug 21 |
r05 | | AEK | 0 - 1 | Asteras Trip |
| 21 Aug 21 |
r05 | | Sabadell | 1 - 0 | Andorra |
| 21 Aug 21 |
r05 | | Aris Limasso | 4 - 1 | Giannina |
| 21 Aug 21 |
r05 | | Xerez Deport | 2 - 1 | UD San Ferna |
| 22 Aug 21 |
r04 | | Mancha Real | - | CD Toledo |
| 22 Aug 21 |
r05 | | Cacereño | 0 - 3 | Mérida AD |
| 22 Aug 21 |
r04 | | Atlético Ba | - | CD Ibiza Isl |
| 22 Aug 21 |
r05 | | Villanovense | 0 - 0 | Badajoz |
| 22 Aug 21 |
r05 | | AE Prat | 1 - 0 | Cornellà |
| 22 Aug 21 |
r05 | | SK Tirana | 1 - 0 | KF Vllaznia |
| 22 Aug 21 |
r05 | | Cerdanyola d | 0 - 2 | Espanyol B |
| 22 Aug 21 |
r05 | | Talavera | 1 - 0 | Unionistas d |
| 23 Aug 21 |
r04 | | Sp Gijon B | 2 - 0 | Polvorín |
| 23 Aug 21 |
r05 | | Sakaryaspor | 1 - 1 | Kırklarelis |
| 25 Aug 21 |
r05 | | Nea Salamis | 1 - 1 | Doxa Katokop |
| 25 Aug 21 |
r05 | | Ayia Napa | 1 - 0 | Omonia Aradi |
| 25 Aug 21 |
r04 | | Don Benito | 4 - 0 | Calvo Sotelo |
| 25 Aug 21 |
r05 | | Voždovac | 0 - 2 | Oman |
| 25 Aug 21 |
r05 | | Villarrobled | 2 - 1 | Mérida AD |
| 26 Aug 21 |
r05 | | Pafos FC | 0 - 0 | Karmiotissa |
| 27 Aug 21 |
r05 | | AEL Limassol | 2 - 1 | Othellos |
| 27 Aug 21 |
r05 | | Onisilos | 0 - 0 | Enosis Neon |
| 27 Aug 21 |
r05 | | AEK Larnaca | 2 - 1 | Aris Limasso |
| 27 Aug 21 |
r03 | | AEL Limassol | - | AEZ |
| 27 Aug 21 |
r03 | | Olympiada Ly | 0 - 1 | Doxa Katokop |
| 28 Aug 21 |
r04 | | Karmiotissa | 2 - 0 | Akritas Chlo |
| 28 Aug 21 |
r04 | | Covadonga | 0 - 3 | Langreo |
| 28 Aug 21 |
r04 | | Haro Deporti | 1 - 1 | Náxara |
| 28 Aug 21 |
r04 | | CE Europa | 0 - 0 | Olot |
| 28 Aug 21 |
r04 | | Hercules | 1 - 2 | Eldense |
| 28 Aug 21 |
r03 | | Panathinaiko | 1 - 1 | Asteras Trip |
| 28 Aug 21 |
r03 | | Aris | 1 - 1 | Lamia |
| 28 Aug 21 |
r05 | | Ourense | 2 - 2 | Coruxo |
| 28 Aug 21 |
r03 | | Panionios | 1 - 1 | Ionikos |
| 28 Aug 21 |
r03 | | AEL Limassol | - | Achyronas Li |
| 28 Aug 21 |
r05 | | Barakaldo | 0 - 0 | Arenas Club |
| 28 Aug 21 |
r05 | | Salamanca UD | 0 - 1 | Guijuelo |
| 28 Aug 21 |
r05 | | Osasuna B | 0 - 2 | Ebro |
| 28 Aug 21 |
r04 | | Nea Salamis | 2 - 0 | Alki Oroklin |
| 28 Aug 21 |
r04 | | Enosis Neon | 1 - 1 | Achyronas Li |
| 28 Aug 21 |
r04 | | Anagennisi D | 2 - 0 | Omonia Aradi |
| 29 Aug 21 |
r04 | | Cacereño | 2 - 2 | Leganés II |
| 29 Aug 21 |
r04 | | Mérida AD | 0 - 0 | Recreativo |
| 29 Aug 21 |
r03 | | Apoel Nicosi | 1 - 2 | Xylotymbou |
| 29 Aug 21 |
r03 | | NFC Volos | 4 - 3 | AEK |
| 31 Aug 21 |
r04 | | Guijuelo | 0 - 1 | Zamora |
| 31 Aug 21 |
r03 | | Numancia | 1 - 1 | Osasuna |
| 01 Sep 21 |
r03 | | Lichtenberg | 0 - 2 | Union Berlin |
| 01 Sep 21 |
r03 | | Dunav Ruse | 0 - 0 | Cherno More |
| 01 Sep 21 |
r03 | | Wolfsburg | 3 - 3 | Hannover |
| 01 Sep 21 |
r03 | | Shooting Sta | 4 - 0 | Tabor Sežan |
| 02 Sep 21 |
r03 | | Austria Lust | 0 - 4 | St. Gallen |
| 02 Sep 21 |
r03 | | ŠKF Sereď | 2 - 0 | Floridsdorfe |
| 02 Sep 21 |
r03 | | NK Istra 196 | 0 - 1 | Opatija |
| 02 Sep 21 |
r03 | | Stuttgart | 3 - 0 | Nurnberg |
| 02 Sep 21 |
r03 | | Fortuna Düs | 1 - 0 | St.Truiden |
| 02 Sep 21 |
r03 | | Mainz | 0 - 0 | Karlsruhe |
| 02 Sep 21 |
r03 | | Lask Juniors | 3 - 7 | LASK |
| 02 Sep 21 |
r01 | | Besiktas | 4 - 0 | Ümraniyespo |
| 02 Sep 21 |
r03 | | FC Utrecht | 3 - 1 | Cercle Brugg |
| 02 Sep 21 |
r03 | | SK Vorwarts | 0 - 3 | SKU Amstette |
| 03 Sep 21 |
r03 | | Achyronas Li | 0 - 8 | Olympiakos N |
| 03 Sep 21 |
r03 | | Nea Salamis | 2 - 1 | PAEEK |
| 03 Sep 21 |
r03 | | Aris | 1 - 1 | Olympiakos |
| 03 Sep 21 |
r03 | | Anorthosis F | 5 - 1 | Karmiotissa |
| 03 Sep 21 |
r03 | | OFI | 1 - 0 | Ergotelis |
| 03 Sep 21 |
r03 | | Rakow Czesto | 5 - 2 | Videoton FC |
| 03 Sep 21 |
r03 | | Aris Limasso | 0 - 0 | AEL Limassol |
| 03 Sep 21 |
r03 | | SC Rheindorf | 1 - 3 | Vaduz |
| 03 Sep 21 |
r03 | | Dynamo Dresd | 4 - 0 | Ústí nad L |
| 03 Sep 21 |
r03 | | Slask Wrocla | 2 - 3 | Tychy 71 |
| 03 Sep 21 |
r03 | | Kispest Honv | 0 - 1 | Budafoki MTE |
| 03 Sep 21 |
r03 | | Toulouse | 3 - 2 | Pau FC |
| 03 Sep 21 |
r03 | | Stal Mielec | 1 - 0 | Nieciecza |
| 03 Sep 21 |
r03 | | Górnik Polk | 2 - 0 | Chrobry Gło |
| 03 Sep 21 |
r03 | | Pardubice | 2 - 1 | Vlašim |
| 03 Sep 21 |
r03 | | Braga | 3 - 2 | Villarreal |
| 03 Sep 21 |
r03 | | Brest | 2 - 4 | Guingamp |
| 03 Sep 21 |
r03 | | TSC Bačka T | 2 - 1 | Ferencvaros |
| 03 Sep 21 |
r03 | | Sturm Graz | 1 - 1 | NK Bravo |
| 03 Sep 21 |
r03 | | Grasshoppers | 5 - 2 | Dornbirn |
| 03 Sep 21 |
r03 | | Slavia Sofia | 0 - 1 | Botev Plovdi |
| 03 Sep 21 |
r03 | | Metz | 0 - 3 | Auxerre |
| 03 Sep 21 |
r03 | | Doxa Katokop | 2 - 2 | Omonia 29is |
| 03 Sep 21 |
r03 | | Szombathelyi | 0 - 1 | SKN St. Polt |
| 03 Sep 21 |
r03 | | Levski Sofia | 2 - 1 | Sportist Svo |
| 03 Sep 21 |
r03 | | ASIL | 10 - 0 | Ethnikos Ach |
| 03 Sep 21 |
r03 | | Kisvárda FC | 2 - 1 | Veres Rivne |
| 03 Sep 21 |
r03 | | Vasas | 0 - 1 | Mynai |
| 03 Sep 21 |
r03 | | Lokomotiv Pl | 1 - 0 | CSKA 1948 II |
| 03 Sep 21 |
r03 | | Lecce | 3 - 2 | U.S.D. Citt� |
| 03 Sep 21 |
r03 | | AEK Larnaca | 3 - 0 | Enosis Neon |
| 03 Sep 21 |
r03 | | Olympiakos N | 0 - 8 | Achyronas Li |
| 04 Sep 21 |
r03 | | Slaven Belup | 4 - 1 | Cibalia |
| 04 Sep 21 |
r03 | | Aue | 6 - 0 | Hallescher F |
| 04 Sep 21 |
r03 | | Alessandria | 3 - 2 | Genoa |
| 04 Sep 21 |
r03 | | Academica Cl | 1 - 1 | FC U Craiova |
| 04 Sep 21 |
r03 | | Zorya | 3 - 1 | Inhulets |
| 04 Sep 21 |
r03 | | ArzignanoChi | 1 - 1 | L.R. Vicenza |
| 04 Sep 21 |
r03 | | U.S.D. Real | 2 - 8 | Empoli |
| 04 Sep 21 |
r03 | | NK Lokomotiv | 3 - 0 | NK Maribor |
| 04 Sep 21 |
r03 | | Udinese | 4 - 1 | Dolomiti Bel |
| 04 Sep 21 |
r03 | | SC Dnipro-1 | 1 - 1 | FC Olexandri |
| 04 Sep 21 |
r03 | | NFC Volos | 2 - 0 | Niki Volou |
| 04 Sep 21 |
r03 | | Sassuolo | 0 - 2 | Cremonese |
| 04 Sep 21 |
r03 | | Brescia | 4 - 0 | Venezia |
| 04 Sep 21 |
r03 | | Pandurii | - | FC U Craiova |
| 04 Sep 21 |
r03 | | GKS Katowice | 0 - 2 | Banik Ostrav |
| 04 Sep 21 |
r03 | | Uta Arad | 0 - 0 | Kolubara |
| 04 Sep 21 |
r03 | | Panetolikos | 3 - 1 | Panathinaiko |
| 04 Sep 21 |
r03 | | Lamezia Term | 0 - 2 | Reggina |
| 04 Sep 21 |
r03 | | Vorskla | 1 - 2 | FC Metalist |
| 04 Sep 21 |
r02 | | Istanbul Bas | 3 - 1 | Karagumruk |
| 04 Sep 21 |
r02 | | Kasimpasa | 0 - 3 | Tuzlaspor |
| 04 Sep 21 |
r02 | | Antalyaspor | 2 - 1 | Rizespor |
| 04 Sep 21 |
r03 | | Lokomotiv So | 0 - 1 | CSKA 1948 |
| 04 Sep 21 |
r03 | | CSA Steaua B | 1 - 2 | FC Voluntari |
| 04 Sep 21 |
r03 | | Beroe | 1 - 3 | Arda Kardzha |
| 04 Sep 21 |
r03 | | Arges Pitest | 2 - 2 | Rapid Bucure |
| 04 Sep 21 |
r03 |  | NK Aluminij | 2 - 0 | Domzale |
| 04 Sep 21 |
r03 | | FC Minsk | 1 - 5 | BATE Borisov |
| 04 Sep 21 |
r04 | | Zejtun Corin | 0 - 2 | Pietà Hotsp |
| 04 Sep 21 |
r03 | | Sampdoria | 3 - 1 | Ternana |
| 04 Sep 21 |
r03 | | Wisla Plock | 0 - 1 | Stomil Olszt |
| 04 Sep 21 |
r03 | | Korona Kielc | 1 - 1 | Radomiak Rad |
| 04 Sep 21 |
r03 | | Napredak Kru | 0 - 2 | Mladost Luč |
| 04 Sep 21 |
r03 | | Zaglebie Lub | 1 - 2 | Lech Poznan |
| 05 Sep 21 |
r03 | | Apollon Lima | 2 - 1 | Onisilos |
| 05 Sep 21 |
r02 | | Galatasaray | 1 - 3 | Farul Consta |
| 05 Sep 21 |
r02 | | Konyaspor | 0 - 3 | Genclerbirli |
| 05 Sep 21 |
r02 | | Goztepe | 5 - 3 | Manisa BBSK |
| 05 Sep 21 |
r03 | | FC Kolos Kov | 2 - 1 | Desna |
| 05 Sep 21 |
r03 | | Isloch Minsk | 2 - 1 | FC Smorgon |
| 05 Sep 21 |
r03 | | SPAL 2013 | 6 - 2 | Rimini |
| 05 Sep 21 |
r03 | | CSKA Moscow | 1 - 2 | Lok. Moscow |
| 05 Sep 21 |
r03 | | CFR Cluj-Nap | 6 - 0 | Gaz Metan Me |
| 05 Sep 21 |
r03 | | Ethnikos Ach | 0 - 1 | Omonia Nicos |
| 05 Sep 21 |
r04 | | GS Arconates | 0 - 0 | A.C. Legnano |
| 06 Sep 21 |
r03 | | FK Rubin Kaz | 1 - 3 | FC Krasnodar |
| 06 Sep 21 |
r03 | | Napoli | 1 - 5 | Benevento |
| 06 Sep 21 |
r03 | | Universitate | 2 - 0 | Metaloglobus |
| 08 Sep 21 |
r05 | | Westerlo | 0 - 5 | St.Truiden |
| 09 Sep 21 |
r04 | | Tiferno Lerc | 3 - 1 | Arezzo |
| 11 Sep 21 |
r05 | | Ergotelis | 1 - 1 | Chania |
| 11 Sep 21 |
r05 | | Kitchee | 2 - 1 | Lee Man |
| 22 Sep 21 |
r05 | | Tusker | 2 - 1 | GOR Mahia |
| 22 Sep 21 |
r05 | | Rejiche | 2 - 0 | CS Hammam-Li |
| 23 Sep 21 |
r05 | | CS Chebba | 2 - 2 | Étoile Spor |
| 03 Oct 21 |
r04 | | Rodos | 2 - 2 | Olympiakos V |
| 05 Oct 21 |
r05 | | Dobrudzha | 0 - 2 | Cherno More |
| 06 Oct 21 |
r05 | | TSV Hartberg | 1 - 0 | SV Kapfenber |
| 06 Oct 21 |
r03 | | Virton | 4 - 2 | UT Pétange |
| 06 Oct 21 |
r05 | | Union Berlin | 1 - 3 | St. Gallen |
| 06 Oct 21 |
r05 | | RasenBallspo | 1 - 2 | Slask Wrocla |
| 06 Oct 21 |
r05 | | Wolfsburg | 4 - 1 | Hamburg |
| 07 Oct 21 |
r03 | | Lübeck | 0 - 2 | Schalke 04 |
| 07 Oct 21 |
r03 | | Rapid Wien I | 3 - 2 | FC BW Linz |
| 07 Oct 21 |
r03 | | Rapid Vienna | - | FC BW Linz |
| 07 Oct 21 |
r03 | | Onisilos | 1 - 7 | Olympiakos N |
| 07 Oct 21 |
r03 | | Wuerzburger | 3 - 1 | Sonnenhof Gr |
| 07 Oct 21 |
r03 | | AIK | 1 - 3 | Joenkoeping |
| 07 Oct 21 |
r03 | | Anderlecht | 4 - 1 | Westerlo |
| 07 Oct 21 |
r05 | | Dornbirn | 0 - 3 | Vaduz |
| 07 Oct 21 |
r03 | | Leon | 1 - 0 | Mazatlán |
| 07 Oct 21 |
r05 | | Holstein Kie | 0 - 0 | Silkeborg IF |
| 07 Oct 21 |
r05 | | Bochum | 5 - 4 | NEC Nijmegen |
| 07 Oct 21 |
r05 | | Go Ahead Eag | 2 - 2 | Lommel SK |
| 07 Oct 21 |
r05 | | CD Guadalaja | 0 - 0 | FAS |
| 07 Oct 21 |
r05 | | Dynamo Dresd | 4 - 0 | Viktoria Ber |
| 07 Oct 21 |
r05 | | FC Utrecht | 3 - 2 | Sparta |
| 07 Oct 21 |
r05 | | Stuttgart | 1 - 4 | Sandhausen |
| 07 Oct 21 |
r03 | | KV Oostende | 5 - 2 | Waregem |
| 07 Oct 21 |
r05 | | Freiburg | 3 - 0 | St Pauli |
| 07 Oct 21 |
r05 | | Augsburg | 1 - 0 | Jahn Regensb |
| 07 Oct 21 |
r05 | | FC Liefering | 1 - 1 | SKU Amstette |
| 07 Oct 21 |
r05 | | SKN St. Polt | - | Floridsdorfe |
| 07 Oct 21 |
r05 | | Schalke 04 | 2 - 0 | Lübeck |
| 07 Oct 21 |
r05 | | Hostert | 2 - 3 | Swift Hesper |
| 08 Oct 21 |
r03 | | Dukla Praha | 4 - 3 | Bohemians 19 |
| 08 Oct 21 |
r03 | | Domzale | 1 - 2 | Sesvete |
| 08 Oct 21 |
r03 | | Kisvárda FC | 4 - 1 | Mynai |
| 08 Oct 21 |
r03 | | Vasas | 2 - 1 | Újpest FC |
| 08 Oct 21 |
r03 | | PAEEK | 2 - 3 | Olympiakos N |
| 08 Oct 21 |
r03 | | San Jose Ear | 2 - 0 | Cruz Azul |
| 08 Oct 21 |
r03 | | Arda Kardzha | 3 - 0 | Maritsa Plov |
| 08 Oct 21 |
r03 | | Liberec | 0 - 0 | Chrudim |
| 08 Oct 21 |
r03 | | RFC Seraing | - | Mouscron-Per |
| 08 Oct 21 |
r03 | | Kispest Honv | 3 - 0 | Siófok |
| 08 Oct 21 |
r03 | | Budafoki MTE | 0 - 2 | Paksi FC |
| 08 Oct 21 |
r02 | | Istanbul Bas | 3 - 1 | Kocaelispor |
| 08 Oct 21 |
r03 | | Nurnberg | 0 - 7 | Ingolstadt |
| 08 Oct 21 |
r03 | | Rijeka | 6 - 1 | Olimpija Lju |
| 08 Oct 21 |
r05 | | SV Josko Rie | 2 - 1 | SK Vorwarts |
| 08 Oct 21 |
r03 | | KMSK Deinze | - | Mechelen |
| 08 Oct 21 |
r03 | | Lechia Gdań | 5 - 0 | Stomil Olszt |
| 08 Oct 21 |
r03 | | Tsarsko Selo | 0 - 2 | Lokomotiv Pl |
| 08 Oct 21 |
r05 | | Dukla Praha | 4 - 3 | Bohemians |
| 09 Oct 21 |
r03 | | Ludogorets R | 2 - 2 | Yantra Gabro |
| 09 Oct 21 |
r04 | | Arges Pitest | 4 - 0 | Concordia |
| 09 Oct 21 |
r05 | | Borec | 2 - 0 | Vardar |
| 09 Oct 21 |
r01 | | Juventus | 2 - 1 | Alessandria |
| 09 Oct 21 |
r02 | | Altınordu | 0 - 1 | Goztepe |
| 09 Oct 21 |
r02 | | Galatasaray | 4 - 3 | Tuzlaspor |
| 09 Oct 21 |
r03 | | CF America | 0 - 1 | Pumas |
| 09 Oct 21 |
r03 | | Steaua Bucur | - | FC Voluntari |
| 09 Oct 21 |
r03 | | CSA Steaua B | 2 - 1 | FC Voluntari |
| 09 Oct 21 |
r03 | | CSKA 1948 | 2 - 0 | Marek Dupnit |
| 09 Oct 21 |
r03 | | Gaz Metan Me | 2 - 0 | SCM Gloria B |
| 09 Oct 21 |
r03 | | Dinamo Bucur | 3 - 2 | Petrolul |
| 09 Oct 21 |
r03 | | BATE Borisov | 2 - 1 | Isloch Minsk |
| 09 Oct 21 |
r03 | | Zaglebie Lub | 1 - 1 | Chrobry Gło |
| 09 Oct 21 |
r03 | | CS Mioveni | 1 - 0 | Rapid Bucure |
| 09 Oct 21 |
r03 | | Diosgyor | 1 - 4 | Mezőkövesd |
| 09 Oct 21 |
r03 | | Rakow Czesto | 1 - 0 | Podbeskidzie |
| 09 Oct 21 |
r03 | | HNK Gorica | - | Slaven Belup |
| 09 Oct 21 |
r03 | | SC Dnipro-1 | 2 - 2 | FC Metalist |
| 09 Oct 21 |
r03 | | Lech Poznan | 5 - 1 | LKS Lodz |
| 09 Oct 21 |
r03 | | Dynamo Brest | 3 - 2 | Neman Grodno |
| 09 Oct 21 |
r03 | | FC Krasnodar | 2 - 1 | FK Rubin Kaz |
| 09 Oct 21 |
r03 | | Udinese | 2 - 1 | Tabor Sežan |
| 09 Oct 21 |
r03 | | Empoli | 2 - 1 | Ternana |
| 10 Oct 21 |
r02 | | Malatyaspor | 0 - 1 | Gaziantep FK |
| 10 Oct 21 |
r03 | | Toluca | 0 - 2 | Tigres |
| 10 Oct 21 |
r03 | | CD Guadalaja | - | Leon |
| 10 Oct 21 |
r03 | | CSKA Moscow | 1 - 1 | Nizhny Novgo |
| 10 Oct 21 |
r03 | | Khimki FK | 2 - 2 | FK Arsenal D |
| 10 Oct 21 |
r03 | | FC Lviv | 2 - 0 | Veres Rivne |
| 10 Oct 21 |
r02 | | Karagumruk | 1 - 0 | Bursaspor |
| 10 Oct 21 |
r02 | | Konyaspor | 2 - 0 | Keçiöreng� |
| 11 Oct 21 |
r03 | | CFR Cluj-Nap | 4 - 0 | Unirea Dej |
| 11 Oct 21 |
r03 | | Ural S.R | 1 - 1 | Krylya Sovet |
| 12 Oct 21 |
r03 | | Levski Sofia | 4 - 0 | Strumska Sla |
| 12 Oct 21 |
r02 | | Kayserispor | 2 - 0 | Genclerbirli |
| 12 Oct 21 |
r02 | | Galatasaray | 3 - 3 | Istanbulspor |
| 30 Oct 21 |
r03 | | Dinamo Minsk | 2 - 2 | Isloch Minsk |
| 10 Nov 21 |
r03 | | Achyronas Li | 1 - 3 | Olympiakos N |
| 10 Nov 21 |
r03 | | Wolfsburg | 1 - 3 | Hansa Rostoc |
| 10 Nov 21 |
r03 | | FC Koln | 4 - 0 | Paderborn |
| 10 Nov 21 |
r03 | | Stuttgart | 1 - 0 | Zurich |
| 10 Nov 21 |
r03 | | Esbjerg | 2 - 1 | AGF Aarhus |
| 11 Nov 21 |
r03 | | Gent | 1 - 3 | Kortrijk |
| 11 Nov 21 |
r05 | | Besiktas | 3 - 0 | Shkupi |
| 11 Nov 21 |
r03 | | Oud-Heverlee | 0 - 2 | Genk |
| 11 Nov 21 |
r03 | | KV Oostende | 4 - 4 | KMSK Deinze |
| 11 Nov 21 |
r03 | | Cherno More | 3 - 1 | Dobrudzha |
| 11 Nov 21 |
r03 | | Karlsruhe | 1 - 2 | Freiburg |
| 11 Nov 21 |
r03 | | Nurnberg | 2 - 0 | SC Rheindorf |
| 11 Nov 21 |
r03 | | Fortuna Düs | 2 - 1 | SC Heracles |
| 11 Nov 21 |
r03 | | Osnabrueck | 2 - 1 | SC Heerenvee |
| 11 Nov 21 |
r03 | | St Pauli | 2 - 2 | Viborg |
| 11 Nov 21 |
r03 | | Hamburg | 7 - 4 | FC Nordsjæl |
| 11 Nov 21 |
r03 | | Grasshoppers | 3 - 1 | Vaduz |
| 11 Nov 21 |
r03 | | SV Meppen | 0 - 3 | Go Ahead Eag |
| 11 Nov 21 |
r03 | | TSV Hartberg | 1 - 1 | NK Bravo |
| 11 Nov 21 |
r03 | | Lask Juniors | 0 - 2 | FC BW Linz |
| 11 Nov 21 |
r03 | | Jahn Regensb | 3 - 1 | Aue |
| 11 Nov 21 |
r03 | | Apollon Lima | 4 - 1 | Omonia Aradi |
| 11 Nov 21 |
r03 | | Lask Juniors | - | TSV Hartberg |
| 11 Nov 21 |
r03 | | SV Horn | 1 - 1 | Rapid Wien I |
| 11 Nov 21 |
r03 | | RasenBallspo | 2 - 1 | FC Eilenburg |
| 12 Nov 21 |
r03 | | Aalesund | - | Molde |
| 12 Nov 21 |
r03 | | Gornik Zabrz | 0 - 1 | SFC Opava |
| 12 Nov 21 |
r03 |  | Videoton FC | 2 - 0 | Budafoki MTE |
| 12 Nov 21 |
r03 | | TSC Bačka T | 0 - 0 | Szeged-Csan� |
| 12 Nov 21 |
r03 | | Kispest Honv | 1 - 0 | Budaörs |
| 12 Nov 21 |
r03 | | Petrolul | 1 - 4 | Chindia Târ |
| 12 Nov 21 |
r03 | | Cercle Brugg | 5 - 1 | Mouscron-Per |
| 12 Nov 21 |
r03 | | Chrudim | 0 - 3 | Bohemians 19 |
| 12 Nov 21 |
r03 | | Stal Mielec | 1 - 1 | Wisla Krakow |
| 12 Nov 21 |
r03 | | NK Lokomotiv | 3 - 2 | Dubrava |
| 12 Nov 21 |
r03 | | Tsarsko Selo | 2 - 2 | Sportist Svo |
| 12 Nov 21 |
r03 | | Westerlo | 4 - 0 | Beerschot VA |
| 12 Nov 21 |
r03 | | Osijek | 2 - 0 | Szentlőrinc |
| 12 Nov 21 |
r03 | | Slaven Belup | 2 - 1 | Rudeš |
| 12 Nov 21 |
r04 | | Diosgyor | 1 - 1 | Szolnok |
| 12 Nov 21 |
r03 | | Domzale | 2 - 3 | Opatija |
| 12 Nov 21 |
r03 | | Metz | 2 - 1 | Kaiserslaute |
| 12 Nov 21 |
r03 | | St. Gallen | 3 - 4 | Wacker Innsb |
| 12 Nov 21 |
r03 | | OFI | 0 - 2 | Olympiakos N |
| 13 Nov 21 |
r02 | | Kasimpasa | 0 - 1 | Istanbulspor |
| 13 Nov 21 |
r02 | | Ümraniyespo | 1 - 3 | Istanbul Bas |
| 13 Nov 21 |
r03 | | FC Smorgon | 2 - 0 | Isloch Minsk |
| 13 Nov 21 |
r03 | | FC Voluntari | 6 - 0 | Metaloglobus |
| 13 Nov 21 |
r03 | | Gaz Metan Me | 2 - 2 | FC Hermannst |
| 13 Nov 21 |
r02 | | Rizespor | 1 - 4 | Erzurumspor |
| 13 Nov 21 |
r03 | | Zaglebie Sos | 1 - 1 | Tychy 71 |
| 13 Nov 21 |
r02 | | Karagumruk | 4 - 3 | Kocaelispor |
| 13 Nov 21 |
r03 | | SCM Gloria B | 2 - 3 | Dinamo Bucur |
| 13 Nov 21 |
r01 | | Galatasaray | 5 - 2 | Bursaspor |
| 13 Nov 21 |
r03 | | Rakow Czesto | 0 - 1 | Wisla Plock |
| 13 Nov 21 |
r03 | | Tabor Sežan | 2 - 1 | Venezia |
| 13 Nov 21 |
r03 | | Levski Sofia | 0 - 1 | Pirin Blagoe |
| 13 Nov 21 |
r03 | | Dinamo Minsk | 0 - 1 | FC Slutsk |
| 13 Nov 21 |
r03 | | Beroe | 1 - 2 | Arda Kardzha |
| 13 Nov 21 |
r03 | | Mynai | 2 - 2 | FC Lviv |
| 13 Nov 21 |
r03 | | FC U Craiova | 4 - 1 | CSA Steaua B |
| 13 Nov 21 |
r03 | | HNK Gorica | 3 - 3 | Celje |
| 13 Nov 21 |
r03 | | Empoli | 1 - 1 | Perugia |
| 13 Nov 21 |
r03 | | Udinese | 2 - 2 | Koper |
| 13 Nov 21 |
r02 | | Antalyaspor | 1 - 1 | Samsunspor |
| 13 Nov 21 |
r02 | | Goztepe | 1 - 2 | Manisa BBSK |
| 14 Nov 21 |
r03 | | Universitate | 2 - 1 | ACS Sirineas |
| 14 Nov 21 |
r03 | | CSKA Moscow | 3 - 1 | FC Ufa |
| 14 Nov 21 |
r03 | | Khimki FK | 0 - 4 | Krylya Sovet |
| 14 Nov 21 |
r03 | | FC Yessentuk | 1 - 7 | Ural S.R |
| 14 Nov 21 |
r03 | | FC Olexandri | 3 - 1 | Inhulets |
| 14 Nov 21 |
r02 | | Kayserispor | 1 - 1 | Sivasspor |
| 14 Nov 21 |
r03 | | CFR Cluj-Nap | 1 - 0 | Unirea Dej |
| 15 Nov 21 |
r03 | | Desna | 1 - 0 | Olimpik Done |
| 17 Nov 21 |
r03 | | Dinamo Bucur | 2 - 1 | Astra |
| 03 Dec 21 |
r03 | | FC Copenhage | - | Silkeborg IF |
| 03 Dec 21 |
r03 | | First Vienna | - | SKN St. Polt |
| 09 Dec 21 |
r03 | | Austria Vien | - | SKN St. Polt |
| 10 Dec 21 |
r05 | | FC Lahti | - | FC Haka |
| 11 Dec 21 |
r05 | | KuPS Kuopio | 3 - 3 | AC Oulu |
| 14 Dec 21 |
r01 | | Barcelona | 1 - 1 | Boca Juniors |
| 17 Dec 21 |
r05 | | MP | 3 - 3 | Ilves |
| 17 Dec 21 |
r05 | | FC Haka | 1 - 4 | KuPS Kuopio |
| 18 Dec 21 |
r03 | | FC Haka | 0 - 3 | Ilves |
| 18 Dec 21 |
r03 | | KuPS Kuopio | 3 - 0 | MP |
| 21 Dec 21 |
r05 | | Venados | 1 - 2 | Cruz Azul |
| 23 Dec 21 |
r04 | | Nam Dinh | 1 - 5 | Binh Duong |
| 23 Dec 21 |
r04 | | Khanh Hoa FC | 2 - 1 | Sai Gon |
| 23 Dec 21 |
r05 | | Atletico de | 3 - 1 | Necaxa |
| 25 Dec 21 |
r04 | | Binh Duong | 2 - 1 | Ba Ria Vung |
| 25 Dec 21 |
r04 | | Khanh Hoa FC | 2 - 2 | Nam Dinh |
| 25 Dec 21 |
r03 | | Energetik-BG | 3 - 3 | Isloch Minsk |
| 29 Dec 21 |
r05 | | Energetik-BG | 2 - 1 | Isloch Minsk |
| 29 Dec 21 |
r04 | | UCAM Murcia | 3 - 0 | Murcia |
| 30 Dec 21 |
r04 | | Numancia | 5 - 0 | Racing Rioja |
| 30 Dec 21 |
r04 | | Campinense | 1 - 1 | Globo |
| 30 Dec 21 |
r05 | | Necaxa | 2 - 3 | CD Guadalaja |
| 04 Jan 22 |
r05 | | Wolfsburg | 5 - 4 | Paderborn |
| 05 Jan 22 |
r05 | | Waldhof Mann | - | Hansa Rostoc |
| 05 Jan 22 |
r05 | | Holstein Kie | 5 - 0 | TSV Havelse |
| 05 Jan 22 |
r05 | | FC Heidenhei | 2 - 1 | Beerschot VA |
| 05 Jan 22 |
r05 | | Werder Breme | - | St.Truiden |
| 05 Jan 22 |
r05 | | Karlsruhe | 0 - 0 | Club Brugge |
| 05 Jan 22 |
r05 | | Club Brugge | - | Karlsruhe |
| 05 Jan 22 |
r05 | | Farnborough | 1 - 0 | Bournemouth |
| 06 Jan 22 |
r05 | | FC Groningen | 1 - 1 | SV Meppen |
| 06 Jan 22 |
r05 | | Ingolstadt | 3 - 1 | Wuerzburger |
| 06 Jan 22 |
r05 | | Rödinghause | 0 - 5 | Osnabrueck |
| 06 Jan 22 |
r05 | | Azam | 1 - 0 | Namungo FC |
| 07 Jan 22 |
r05 | | Munich 1860 | 3 - 1 | Hansa Rostoc |
| 07 Jan 22 |
r05 | | Fortuna Köl | 2 - 2 | Duisburg |
| 07 Jan 22 |
r05 | | Go Ahead Eag | 1 - 2 | Dortmund II |
| 07 Jan 22 |
r05 | | Hamburg | - | NEC Nijmegen |
| 07 Jan 22 |
r05 | | Carl Zeiss J | 2 - 3 | Zwickau |
| 07 Jan 22 |
r05 | | Young Africa | 2 - 2 | KMKM FC |
| 07 Jan 22 |
r05 | | Wehen Wiesba | 4 - 1 | Mechelen |
| 07 Jan 22 |
r05 | | Willem II | - | SC Cambuur |
| 07 Jan 22 |
r05 | | Gent | 0 - 1 | AZ Alkmaar |
| 07 Jan 22 |
r05 | | Simba SC | 0 - 0 | Mlandege |
| 08 Jan 22 |
r05 | | Eskisehirspo | 0 - 2 | Türkgücü |
| 08 Jan 22 |
r05 | | Arges Pitest | - | CS Mioveni |
| 08 Jan 22 |
r05 | | Liberec | 0 - 1 | Chrudim |
| 08 Jan 22 |
r05 | | Siófok | 2 - 4 | Soroksár |
| 08 Jan 22 |
r05 | | Zalaegerszeg | 2 - 4 | III Kerület |
| 08 Jan 22 |
r05 | | Zlín | 2 - 2 | Líšeň |
| 08 Jan 22 |
r05 | | Bonner SC | 1 - 1 | Rot-Weiß Ko |
| 08 Jan 22 |
r05 | | Viborg | 2 - 0 | HOBRO |
| 08 Jan 22 |
r05 | | Osijek | 2 - 0 | BSK Bijelo B |
| 08 Jan 22 |
r05 | | Mezőkövesd | 4 - 0 | Szentlőrinc |
| 08 Jan 22 |
r05 | | Hansa Rostoc | - | Samsunspor |
| 08 Jan 22 |
r05 | | Hannover | 2 - 2 | Werder Breme |
| 08 Jan 22 |
r05 | | Feyenoord | P - P | Club Brugge |
| 08 Jan 22 |
r05 | | Young Boys | 6 - 1 | Thun |
| 08 Jan 22 |
r05 | | Schalke 04 | 1 - 1 | Fortuna Sitt |
| 08 Jan 22 |
r05 | | NK Lokomotiv | 4 - 3 | NK Aluminij |
| 08 Jan 22 |
r05 | | Holstein Kie | 3 - 2 | Osnabrueck |
| 08 Jan 22 |
r05 | | Gyirmót | 0 - 2 | Dorog |
| 08 Jan 22 |
r05 | | Fortuna Düs | 2 - 1 | Freiburg II |
| 08 Jan 22 |
r05 | | Mönchenglad | 2 - 3 | Viktoria Kö |
| 08 Jan 22 |
r05 | | Nurnberg | 5 - 1 | Hallescher F |
| 08 Jan 22 |
r05 | | Darmstadt | 4 - 2 | Jahn Regensb |
| 08 Jan 22 |
r05 | | Eupen | 1 - 2 | Kaiserslaute |
| 08 Jan 22 |
r05 | | Rot-Weiß Ob | 6 - 1 | KFC Uerdinge |
| 08 Jan 22 |
r05 | | Preußen Mü | - | Duisburg |
| 08 Jan 22 |
r05 | | Dynamo Dresd | 5 - 0 | Aue |
| 08 Jan 22 |
r05 | | Straelen | - | SC Heracles |
| 08 Jan 22 |
r05 | | SC Verl | 0 - 2 | Paderborn |
| 08 Jan 22 |
r05 | | Werder Breme | - | Cercle Brugg |
| 08 Jan 22 |
r05 | | Drochtersen- | - | Heider SV |
| 08 Jan 22 |
r05 | | FC Basel | 3 - 1 | Sandhausen |
| 08 Jan 22 |
r05 | | SC Kriens | 2 - 1 | Lucerne |
| 08 Jan 22 |
r05 | | FC Koln II | - | Diosgyor |
| 08 Jan 22 |
r05 | | Oud-Heverlee | 1 - 3 | FC Heidenhei |
| 08 Jan 22 |
r05 | | Puskás Akad | - | KMSK Deinze |
| 08 Jan 22 |
r05 | | Rot-Weiss Es | 1 - 2 | SV Meppen |
| 09 Jan 22 |
r05 | | Uta Arad | 1 - 4 | Charleroi |
| 09 Jan 22 |
r05 | | Anderlecht | 2 - 0 | Westerlo |
| 09 Jan 22 |
r05 | | Wuerzburger | 4 - 0 | Aalen |
| 09 Jan 22 |
r05 | | Paderborn | - | SC Heracles |
| 09 Jan 22 |
r05 | | Ajax | - | Hajduk Split |
| 09 Jan 22 |
r05 | | Paksi FC | 2 - 5 | Universitate |
| 09 Jan 22 |
r05 | | Karlsruhe | 2 - 1 | Diosgyor |
| 10 Jan 22 |
r05 | | Rödinghause | 1 - 4 | FC Groningen |
| 10 Jan 22 |
r05 | | Türkgücü | - | FC Botoșani |
| 11 Jan 22 |
r05 | | Rapid Bucure | 1 - 3 | Samsunspor |
| 11 Jan 22 |
r05 | | Dortmund II | 4 - 0 | Aachen |
| 11 Jan 22 |
r05 | | Gaz Metan Me | 2 - 1 | Vaduz |
| 11 Jan 22 |
r05 | | Grasshoppers | 2 - 2 | FC Wil |
| 11 Jan 22 |
r05 | | Dinamo Zagre | 2 - 0 | Olimpija Lju |
| 11 Jan 22 |
r05 | | Fortuna Düs | - | TSV Steinbac |
| 11 Jan 22 |
r05 | | Diosgyor | 0 - 2 | KMSK Deinze |
| 11 Jan 22 |
r05 | | Linfield | 0 - 1 | Larne |
| 12 Jan 22 |
r05 | | Dinamo Bucur | P - P | CS Mioveni |
| 12 Jan 22 |
r05 | | NK Istra 196 | 0 - 2 | Žarkovo |
| 12 Jan 22 |
r05 | | Viktoria Plz | 6 - 0 | Pribram |
| 12 Jan 22 |
r05 | | Dynamo Česk | 1 - 0 | Táborsko |
| 12 Jan 22 |
r05 | | Liberec | - | Varnsdorf |
| 12 Jan 22 |
r05 | | Sparta Pragu | 5 - 0 | Chrudim |
| 12 Jan 22 |
r05 | | CS Mioveni | 2 - 0 | Dinamo Batum |
| 12 Jan 22 |
r05 | | Wisla Krakow | 3 - 0 | Tatran Lipto |
| 12 Jan 22 |
r05 | | NK Bravo | 1 - 1 | Budafoki MTE |
| 12 Jan 22 |
r05 | | Paksi FC | 3 - 0 | Chindia Târ |
| 12 Jan 22 |
r05 | | Lugano | 1 - 2 | FC Basel |
| 12 Jan 22 |
r05 | | Uta Arad | - | Kispest Honv |
| 12 Jan 22 |
r05 | | Soroksár | - | Zalaegerszeg |
| 12 Jan 22 |
r05 | | Gyirmót | - | III Kerület |
| 12 Jan 22 |
r05 | | Debrecen | 4 - 0 | Kazincbarcik |
| 12 Jan 22 |
r05 |  | Zalaegerszeg | 1 - 0 | Videoton FC |
| 12 Jan 22 |
r05 | | Rijeka | 2 - 3 | Domzale |
| 12 Jan 22 |
r05 | | Universitate | - | Raufoss |
| 12 Jan 22 |
r05 | | Young Boys | 4 - 2 | Servette |
| 12 Jan 22 |
r05 | | SV Kapfenber | - | NŠ Mura |
| 12 Jan 22 |
r05 | | Tennis Borus | - | Viktoria Ber |
| 12 Jan 22 |
r05 | | Aimoré | 0 - 0 | Caxias |
| 13 Jan 22 |
r05 | | Slavia Sofia | 3 - 1 | Hebar Pazard |
| 13 Jan 22 |
r05 | | Zurich | 3 - 3 | Wuppertaler |
| 13 Jan 22 |
r05 | | Hajduk Split | - | Servette |
| 13 Jan 22 |
r05 | | Dugopolje | 3 - 0 | Opatija |
| 13 Jan 22 |
r05 | | St. Gallen | 5 - 5 | FC Winterthu |
| 13 Jan 22 |
r05 | | Rapid Vienna | 4 - 0 | SV Lafnitz |
| 13 Jan 22 |
r05 | | FC Aarau | 4 - 1 | FC Voluntari |
| 13 Jan 22 |
r05 | | Lechia Gdań | 3 - 2 | FC Botoșani |
| 13 Jan 22 |
r05 | | CFR Cluj-Nap | 1 - 0 | La Nucía |
| 13 Jan 22 |
r05 | | UD Ibiza | 1 - 1 | Peña Deport |
| 14 Jan 22 |
r05 | | Malaga | - | Puskás Akad |
| 14 Jan 22 |
r05 | | MTK Hungaria | - | Csákvár |
| 14 Jan 22 |
r05 | | Real Unión | 0 - 1 | Eibar |
| 14 Jan 22 |
r05 | | HOBRO | 0 - 3 | Randers FC |
| 14 Jan 22 |
r05 | | Slask Wrocla | 1 - 0 | Warta Pozna� |
| 14 Jan 22 |
r05 | | Liberec | 2 - 0 | Chindia Târ |
| 14 Jan 22 |
r05 | | FC U Craiova | 3 - 0 | 1599 Șelimb |
| 14 Jan 22 |
r05 | | Neftçi PFK | 2 - 2 | Kisvárda FC |
| 14 Jan 22 |
r05 | | HNK Gorica | 4 - 0 | Radomlje |
| 14 Jan 22 |
r05 | | Austria Lust | 1 - 1 | WSG Swarovsk |
| 14 Jan 22 |
r05 | | Rakow Czesto | 1 - 2 | Rapid Bucure |
| 14 Jan 22 |
r05 | | Szombathelyi | - | TSV Hartberg |
| 14 Jan 22 |
r05 | | Banik Ostrav | - | FC U Craiova |
| 14 Jan 22 |
r05 | | FC Aarau | 2 - 1 | Uta Arad |
| 14 Jan 22 |
r05 | | SV Salzburg | 6 - 0 | SKU Amstette |
| 14 Jan 22 |
r05 | | Diosgyor | - | Waasland-Bev |
| 14 Jan 22 |
r05 | | Europa Point | 0 - 8 | Diosgyor |
| 14 Jan 22 |
r05 | | Khalidiya | 1 - 3 | Cordoba |
| 14 Jan 22 |
r05 | | Slavia Pragu | - | Servette |
| 14 Jan 22 |
r05 | | Viborg | 5 - 0 | Jammerbugt |
| 14 Jan 22 |
r05 | | Wiener Neust | 5 - 0 | Austria Vien |
| 14 Jan 22 |
r05 | | B.93 | 0 - 1 | Hvidovre IF |
| 14 Jan 22 |
r05 | | Frem | 0 - 5 | AB Gladsaxe |
| 14 Jan 22 |
r05 | | Figueirense | 0 - 0 | Brusque |
| 15 Jan 22 |
r05 | | Alianza Lima | 3 - 2 | La Equidad |
| 15 Jan 22 |
r05 | | Energetik-BG | 1 - 0 | FC Minsk |
| 15 Jan 22 |
r05 | | AC Horsens | 5 - 0 | Aarhus Frema |
| 15 Jan 22 |
r05 | | Viktoria Plz | 1 - 0 | Ústí nad L |
| 15 Jan 22 |
r05 | | Domzale | 2 - 2 | Budafoki MTE |
| 15 Jan 22 |
r05 | | FC Lausanne- | 1 - 1 | Stade Lausan |
| 15 Jan 22 |
r05 | | Kolding IF | 0 - 2 | Sønderjyske |
| 15 Jan 22 |
r05 | | Hradec Král | - | Liberec |
| 15 Jan 22 |
r05 | | Schalke 04 I | - | Stuttgart II |
| 15 Jan 22 |
r05 | | Eldense | 2 - 2 | UCAM Murcia |
| 15 Jan 22 |
r05 | | CS Mioveni | 0 - 0 | Steaua Bucur |
| 15 Jan 22 |
r05 | | Slavoj Vyše | - | Chrudim |
| 15 Jan 22 |
r05 |  | Zbrojovka Br | 3 - 3 | Zlín |
| 15 Jan 22 |
r05 | | Dynamo Česk | 2 - 0 | Pribram |
| 15 Jan 22 |
r05 | | Shakhter Sol | 3 - 0 | Slavia Mozyr |
| 15 Jan 22 |
r05 | | Racing FC Un | 1 - 3 | Elversberg |
| 15 Jan 22 |
r05 | | CD Toledo | 2 - 0 | CD Móstoles |
| 15 Jan 22 |
r05 | | Miedz Legnic | 0 - 2 | Górnik Polk |
| 15 Jan 22 |
r05 | | FC Koln II | 1 - 1 | Rot-Weiß Ko |
| 15 Jan 22 |
r05 | | Dynamo Dresd | 0 - 3 | Carl Zeiss J |
| 15 Jan 22 |
r05 | | Siófok | 2 - 2 | Shkendija 79 |
| 15 Jan 22 |
r05 | | Wanderers | 0 - 1 | Boston River |
| 15 Jan 22 |
r05 | | Young Boys | 5 - 2 | Grasshoppers |
| 15 Jan 22 |
r05 | | Kispest Honv | 0 - 0 | Zalaegerszeg |
| 15 Jan 22 |
r05 | | Legia Warsaw | 2 - 0 | Botev Plovdi |
| 15 Jan 22 |
r05 | | Warta Pozna� | 1 - 0 | Arka Gdynia |
| 15 Jan 22 |
r05 | | Karvina | 1 - 3 | Tatran Lipto |
| 15 Jan 22 |
r05 | | Zaglebie Sos | 2 - 2 | Resovia Rzes |
| 15 Jan 22 |
r05 | | Liverpool Mo | 1 - 1 | Rentistas |
| 15 Jan 22 |
r05 | | Gyor | 5 - 2 | Szolnok |
| 15 Jan 22 |
r05 | | Augsburg II | 1 - 3 | Aalen |
| 15 Jan 22 |
r05 | | LASK | 7 - 1 | Grazer AK |
| 15 Jan 22 |
r05 | | Cottbus | - | Hertha Zehle |
| 15 Jan 22 |
r05 | | Nomme Kalju | 2 - 2 | Tallinna JK |
| 15 Jan 22 |
r05 | | Mezőkövesd | - | Jagiellonia |
| 15 Jan 22 |
r05 | | VfB Homberg | 4 - 2 | Straelen |
| 15 Jan 22 |
r05 | | Lugano | 3 - 0 | Vaduz |
| 15 Jan 22 |
r05 | | Osijek | 3 - 0 | Olimpija Lju |
| 15 Jan 22 |
r05 |  | SJK Seinajok | 1 - 1 | FC Haka |
| 15 Jan 22 |
r05 | | SV Josko Rie | 1 - 1 | SK Vorwarts |
| 15 Jan 22 |
r05 | | Neuchâtel X | 1 - 3 | Thun |
| 15 Jan 22 |
r05 | | Zalaegerszeg | - | NŠ Mura |
| 15 Jan 22 |
r05 | | Wiedenbrück | 1 - 3 | Rot-Weiß Ob |
| 15 Jan 22 |
r05 | | FK Pirmasens | 0 - 4 | Etzella Ette |
| 15 Jan 22 |
r05 | | Aachen | 2 - 4 | Westerlo |
| 15 Jan 22 |
r05 | | CFR Cluj-Nap | - | Ferencvaros |
| 15 Jan 22 |
r05 | | Gyirmót | - | Vasas |
| 15 Jan 22 |
r05 | | KPV | - | SJK Seinajok |
| 15 Jan 22 |
r05 | | PK-35 | - | KTP |
| 15 Jan 22 |
r05 | | FC Gießen | 1 - 2 | Mainz II |
| 15 Jan 22 |
r05 | | Isloch Minsk | 0 - 0 | FC Dnepr Mog |
| 15 Jan 22 |
r05 | | OHiggins | 1 - 0 | Deportes San |
| 15 Jan 22 |
r05 | | Rijeka | 3 - 0 | NK Bravo |
| 15 Jan 22 |
r05 | | Šibenik | 0 - 3 | Žarkovo |
| 15 Jan 22 |
r05 | | Sturm Graz | 0 - 2 | Videoton FC |
| 15 Jan 22 |
r05 | | Lucerne | 0 - 1 | FC Winterthu |
| 15 Jan 22 |
r05 | | Bellinzona | - | Schaffhausen |
| 15 Jan 22 |
r05 | | Paksi FC | 1 - 1 | Sabah FC |
| 15 Jan 22 |
r05 | | Rot Weiss Ah | 3 - 4 | FSV Frankfur |
| 15 Jan 22 |
r05 | | Banik Ostrav | 2 - 4 | Lech Poznan |
| 15 Jan 22 |
r05 | | FC Sion | 0 - 2 | Servette |
| 15 Jan 22 |
r05 | | SC Rheindorf | 1 - 4 | St. Gallen |
| 15 Jan 22 |
r05 | | Düren | 2 - 3 | Wegberg-Beec |
| 15 Jan 22 |
r05 | | Universitate | - | Chornomorets |
| 15 Jan 22 |
r05 | | Lippstadt 08 | 4 - 3 | Hessen Kasse |
| 15 Jan 22 |
r05 | | Dinamo Bucur | 2 - 2 | Farul Consta |
| 15 Jan 22 |
r05 | | FBC Melgar | 1 - 0 | Deportivo Pe |
| 15 Jan 22 |
r05 | | Carlos A Man | - | Atlético Gr |
| 16 Jan 22 |
r05 | | NK Lokomotiv | 2 - 3 | Opatija |
| 16 Jan 22 |
r05 | | NK Varaždin | 1 - 2 | Celje |
| 16 Jan 22 |
r05 | | Pärnu JK Va | 0 - 2 | Paide Linnam |
| 16 Jan 22 |
r05 | | Ferencvaros | - | Spartak Subo |
| 16 Jan 22 |
r05 | | Debrecen | - | Újpest FC |
| 16 Jan 22 |
r05 | | Dugopolje | 5 - 1 | Iskra Danilo |
| 16 Jan 22 |
r05 | | Hajduk Split | 2 - 1 | Siroki Brije |
| 16 Jan 22 |
r05 | | Dinamo Zagre | 4 - 2 | Koper |
| 16 Jan 22 |
r05 | | Zaglebie Lub | 1 - 0 | FC Voluntari |
| 16 Jan 22 |
r05 | | NK Maribor | 4 - 0 | Triglav Kran |
| 16 Jan 22 |
r05 | | Galway Unite | 1 - 0 | Finn Harps F |
| 16 Jan 22 |
r05 | | Belgrano | 2 - 0 | Unión Espa� |
| 17 Jan 22 |
r05 | | Defensor Spo | 0 - 2 | Danubio |
| 17 Jan 22 |
r05 | | Zurich | 1 - 1 | Pogon Szczec |
| 17 Jan 22 |
r05 | | PFC Kuban Kr | - | Bregalnica � |
| 17 Jan 22 |
r05 | | Aktobe | - | MTK Hungaria |
| 17 Jan 22 |
r05 | | Radomiak Rad | - | Kyzylzhar SK |
| 17 Jan 22 |
r05 | | Lechia Gdań | - | Mezőkövesd |
| 17 Jan 22 |
r05 | | Al-Riffa SC | 1 - 1 | Cordoba |
| 17 Jan 22 |
r05 | | SV Salzburg | - | Young Boys |
| 17 Jan 22 |
r05 | | Peñarol | 4 - 0 | Barracas Cen |
| 18 Jan 22 |
r05 | | CD Nacional | 3 - 2 | Ñublense |
| 18 Jan 22 |
r05 | | Belasica | 0 - 4 | Akademija Pa |
| 18 Jan 22 |
r05 | | Rabotnichki | 2 - 1 | Makedonija G |
| 18 Jan 22 |
r05 | | Banik Ostrav | 1 - 0 | Kisvárda FC |
| 18 Jan 22 |
r05 | | Slavia Sofia | 0 - 3 | Stal Mielec |
| 18 Jan 22 |
r05 | | NK Istra 196 | 2 - 1 | Šibenik |
| 18 Jan 22 |
r05 | | Krylya Sovet | 2 - 0 | Szeged-Csan� |
| 18 Jan 22 |
r05 | | PFC Kuban Kr | 0 - 1 | Bregalnica � |
| 18 Jan 22 |
r05 | | Paksi FC | 2 - 0 | FC Ufa |
| 18 Jan 22 |
r05 | | Lechia Gdań | 0 - 2 | Chornomorets |
| 18 Jan 22 |
r05 | | Levski Sofia | 1 - 1 | Gornik Zabrz |
| 18 Jan 22 |
r05 | | SV Salzburg | 3 - 1 | SV Josko Rie |
| 18 Jan 22 |
r05 | | Lech Poznan | 4 - 1 | Shkupi |
| 18 Jan 22 |
r05 | | Unterhaching | - | Sonnenhof Gr |
| 18 Jan 22 |
r05 | | Young Boys | - | SV Salzburg |
| 18 Jan 22 |
r05 | | Cobh Rambler | 0 - 3 | Dundalk |
| 19 Jan 22 |
r05 | | Rakow Czesto | 3 - 0 | Navbahor |
| 19 Jan 22 |
r05 | | Viktoria Plz | 1 - 1 | Zbrojovka Br |
| 19 Jan 22 |
r05 | | MFK Zemplín | 3 - 0 | Kosice |
| 19 Jan 22 |
r05 | | Iskra Danilo | 3 - 3 | Opatija |
| 19 Jan 22 |
r05 | | Beroe | 1 - 1 | Sozopol |
| 19 Jan 22 |
r05 | | Legia Warsaw | 2 - 1 | FC Krasnodar |
| 19 Jan 22 |
r05 | | Slaven Belup | 1 - 1 | Rudeš |
| 19 Jan 22 |
r05 | | Nieciecza | 4 - 1 | MTK Hungaria |
| 19 Jan 22 |
r05 | | Wisla Plock | 1 - 1 | Neftçi PFK |
| 19 Jan 22 |
r05 | | Cracovia Kra | 1 - 2 | Rapid Vienna |
| 19 Jan 22 |
r05 | | FC Basel | 3 - 0 | FC Lausanne- |
| 19 Jan 22 |
r05 | | NK Bravo | - | Gorica |
| 19 Jan 22 |
r05 | | Cherno More | 3 - 3 | Dobrudzha |
| 19 Jan 22 |
r05 | | Piast Gliwic | 1 - 4 | Shkendija 79 |
| 19 Jan 22 |
r05 | | Mlada Bolesl | 4 - 1 | Vysočina Ji |
| 19 Jan 22 |
r05 | | NK Lokomotiv | 7 - 0 | Dugopolje |
| 19 Jan 22 |
r05 | | Dinamo Zagre | 3 - 0 | Domzale |
| 19 Jan 22 |
r05 | | Zenit St Pet | 3 - 0 | Emirates Clu |
| 19 Jan 22 |
r05 | | FC Wil | 0 - 1 | St. Gallen |
| 19 Jan 22 |
r05 | | Zorya | 1 - 3 | Pogon Szczec |
| 19 Jan 22 |
r05 | | Slask Wrocla | 2 - 1 | TSV Hartberg |
| 19 Jan 22 |
r05 | | FC Copenhage | - | B.93 |
| 19 Jan 22 |
r05 | | DAC 1904 Dun | 2 - 0 | Ferencvaros |
| 19 Jan 22 |
r05 | | Korona Kielc | 4 - 1 | Puszcza Niep |
| 19 Jan 22 |
r05 | | Astoria Wall | - | TSV Steinbac |
| 19 Jan 22 |
r05 | | Wacker Nordh | 1 - 4 | Germania Hal |
| 19 Jan 22 |
r05 | | Raufoss | - | Elverum |
| 19 Jan 22 |
r05 | | CD Nacional | 1 - 2 | Barracas Cen |
| 20 Jan 22 |
r05 | | Peñarol | 1 - 0 | Ñublense |
| 20 Jan 22 |
r05 | | Energetik-BG | 4 - 2 | Shakhter Sol |
| 20 Jan 22 |
r05 | | FK Rubin Kaz | 4 - 4 | Fakel Vorone |
| 20 Jan 22 |
r05 | | Orijent 1919 | 3 - 0 | Domzale |
| 20 Jan 22 |
r05 | | Legia Warsaw | 2 - 0 | Riga FC |
| 20 Jan 22 |
r05 | | Odense BK | 2 - 1 | Fredericia |
| 20 Jan 22 |
r05 | | Gornik Leczn | 2 - 2 | Zira FK |
| 20 Jan 22 |
r05 | | PFC Sochi | 4 - 0 | Tomsk |
| 20 Jan 22 |
r05 | | Rijeka | - | Budafoki MTE |
| 20 Jan 22 |
r05 | | Kickers Offe | - | ZFC Meuselwi |
| 20 Jan 22 |
r05 | | Osijek | 3 - 1 | Szombathelyi |
| 20 Jan 22 |
r05 | | Aktobe | 1 - 2 | Polissya Zhy |
| 20 Jan 22 |
r05 | | Lech Poznan | 1 - 2 | Dinamo Batum |
| 21 Jan 22 |
r05 | | Szeged-Csan� | 2 - 1 | Arsenal Tula |
| 21 Jan 22 |
r05 | | Wisla Krakow | 1 - 3 | Banik Ostrav |
| 21 Jan 22 |
r05 | | Radomiak Rad | 2 - 3 | MTK Hungaria |
| 21 Jan 22 |
r05 | | Krasava Odin | 2 - 3 | Peresvet Pod |
| 21 Jan 22 |
r05 | | Qarabag FK | 0 - 1 | TSC Bačka T |
| 21 Jan 22 |
r05 | | Dynamo Česk | - | Mezőkövesd |
| 21 Jan 22 |
r05 | | Rukh Brest | 0 - 0 | Slavia Mozyr |
| 21 Jan 22 |
r05 | | Šibenik | 2 - 0 | Opatija |
| 21 Jan 22 |
r05 | | Sandecja Now | 3 - 5 | Ruch Chorzow |
| 21 Jan 22 |
r05 | | Liberec | 4 - 2 | Warta Pozna� |
| 21 Jan 22 |
r05 | | FC Midtjylla | 5 - 1 | Esbjerg |
| 21 Jan 22 |
r05 | | Renova | - | Struga |
| 21 Jan 22 |
r05 | | MFK Ružombe | 2 - 1 | Podbeskidzie |
| 21 Jan 22 |
r05 | | Rijeka | 1 - 1 | Slovacko |
| 21 Jan 22 |
r05 | | Yverdon Spor | 0 - 1 | Gjilani |
| 21 Jan 22 |
r05 | | Gabala FK | 1 - 0 | Borec |
| 21 Jan 22 |
r05 | | Cottbus | 2 - 1 | Hertha II |
| 21 Jan 22 |
r05 | | Kisvárda FC | - | Kyzylzhar SK |
| 21 Jan 22 |
r05 | | Elversberg | 7 - 0 | Rot-Weiß Ko |
| 21 Jan 22 |
r05 | | DAC 1904 Dun | - | FK Pohronie |
| 21 Jan 22 |
r05 | | CSKA Sofia | 1 - 1 | Stal Mielec |
| 21 Jan 22 |
r05 | | AC Horsens | 2 - 1 | Randers FC |
| 21 Jan 22 |
r05 | | Metallurg Li | - | FK Aksu |
| 21 Jan 22 |
r05 | | Struga | - | Renova |
| 21 Jan 22 |
r05 | | Montana | - | Yantra Gabro |
| 21 Jan 22 |
r05 | | Levski Sofia | 1 - 1 | Bohemians |
| 21 Jan 22 |
r05 | | Wolfsberger | 3 - 3 | Ludogorets R |
| 21 Jan 22 |
r05 | | Cracovia Kra | 4 - 2 | Dynamo Česk |
| 21 Jan 22 |
r05 | | Grasshoppers | 1 - 1 | FC Winterthu |
| 21 Jan 22 |
r05 | | SKA-Khabarov | 2 - 0 | Nyíregyház |
| 21 Jan 22 |
r05 | | NK Aluminij | 0 - 0 | Budafoki MTE |
| 21 Jan 22 |
r05 | | Slask Wrocla | 3 - 2 | Qarabag FK |
| 21 Jan 22 |
r05 | | Norrby | 1 - 2 | Hacken |
| 21 Jan 22 |
r05 | | Jammerbugt | - | Vendsyssel F |
| 21 Jan 22 |
r05 | | Vendsyssel F | - | Aarhus Frema |
| 21 Jan 22 |
r05 | | UT Pétange | 0 - 0 | Fola |
| 21 Jan 22 |
r05 | | Bohemians | 2 - 3 | St Patricks |
| 22 Jan 22 |
r05 | | Dandenong Th | 4 - 0 | Green Gully |
| 22 Jan 22 |
r05 | | Baltika Kali | 1 - 0 | Lokomotiv So |
| 22 Jan 22 |
r05 | | Mlada Bolesl | - | Pribram |
| 22 Jan 22 |
r05 | | SJK Seinajok | 2 - 0 | Paide Linnam |
| 22 Jan 22 |
r05 | | Líšeň | - | Slovan Brati |
| 22 Jan 22 |
r05 | | Kolding IF | - | Middelfart |
| 22 Jan 22 |
r05 | | Viktoria Plz | 0 - 1 | Mlada Bolesl |
| 22 Jan 22 |
r05 | | SV Salzburg | - | Sparta Pragu |
| 22 Jan 22 |
r05 | | Osijek | 3 - 0 | Tabor Sežan |
| 22 Jan 22 |
r05 | | Slavoj Vyše | 0 - 2 | Viktoria Ži |
| 22 Jan 22 |
r05 | | Dubrava | 3 - 2 | Sesvete |
| 22 Jan 22 |
r05 | | NK Istra 196 | 1 - 0 | Dugopolje |
| 22 Jan 22 |
r05 | | Dinamo Minsk | 1 - 1 | Isloch Minsk |
| 22 Jan 22 |
r05 | | FC Flora Tal | 1 - 1 | Pärnu Jalgp |
| 22 Jan 22 |
r05 | | Chrobry Gło | 1 - 3 | Miedz Legnic |
| 22 Jan 22 |
r05 | | Miedz Legnic | - | Chrobry Gło |
| 22 Jan 22 |
r05 | | Gomel | 4 - 0 | FC Belshina |
| 22 Jan 22 |
r05 | | BATE Borisov | 3 - 0 | FC Slutsk |
| 22 Jan 22 |
r05 | | Nykøbing | 3 - 1 | Hillerød |
| 22 Jan 22 |
r05 | | Young Boys | - | FC Winterthu |
| 22 Jan 22 |
r05 | | Dila Gori | 2 - 2 | Sioni |
| 22 Jan 22 |
r05 | | Zaglebie Sos | 0 - 1 | Puszcza Niep |
| 22 Jan 22 |
r05 | | HNK Gorica | 1 - 3 | Rudeš |
| 22 Jan 22 |
r05 | | Køge | 3 - 0 | KFUM Roskild |
| 22 Jan 22 |
r05 | | Widzew Lodz | 1 - 2 | Chojniczanka |
| 22 Jan 22 |
r05 | | Unirea Dej | 0 - 1 | FC Hermannst |
| 22 Jan 22 |
r05 | | Fremad Amage | 4 - 1 | AB Gladsaxe |
| 22 Jan 22 |
r05 | | Dunav Ruse | 2 - 2 | Dobrudzha |
| 22 Jan 22 |
r05 | | Hertha Zehle | 2 - 2 | Tennis Borus |
| 22 Jan 22 |
r05 | | Koper | 2 - 0 | SV Kapfenber |
| 22 Jan 22 |
r05 | | Næstved BK | 3 - 1 | Roskilde |
| 22 Jan 22 |
r05 | | Jastrzębie | 1 - 2 | GKS Katowice |
| 22 Jan 22 |
r05 | | Brøndby | 1 - 4 | Lyngby |
| 22 Jan 22 |
r05 | | Djurgaarden | 3 - 0 | Vaesteraas S |
| 22 Jan 22 |
r05 | | Halmstad | 2 - 0 | Falkenbergs |
| 22 Jan 22 |
r05 | | River Plate | 2 - 1 | Deportivo Ma |
| 22 Jan 22 |
r05 | | Wanderers | 0 - 0 | Rentistas |
| 22 Jan 22 |
r05 | | Rapid Vienna | 1 - 2 | Pogon Szczec |
| 22 Jan 22 |
r05 | | Wexford | 0 - 2 | Shelbourne F |
| 22 Jan 22 |
r05 | | VMFD Zalgiri | 2 - 2 | Rīgas Futbo |
| 22 Jan 22 |
r05 | | Lokomotiv Pl | 3 - 1 | Maritsa Plov |
| 22 Jan 22 |
r05 | | Slavia Sofia | 0 - 5 | Metalist Kha |
| 22 Jan 22 |
r05 | | Hajduk Split | 1 - 1 | Velez Mostar |
| 22 Jan 22 |
r05 | | Landskrona | 2 - 3 | FC Helsingoe |
| 22 Jan 22 |
r05 | | Sumgayit FK | 1 - 2 | Shkupi |
| 22 Jan 22 |
r05 | | Longford Tow | 1 - 1 | Shamrock |
| 22 Jan 22 |
r05 | | Neman Grodno | 3 - 3 | Dynamo Brest |
| 22 Jan 22 |
r05 | | Peresvet Pod | 5 - 2 | FC Kvant Obn |
| 22 Jan 22 |
r05 | | Chemnitzer F | 1 - 1 | SpVgg Bayreu |
| 22 Jan 22 |
r05 | | Bełchatów | 1 - 0 | Znicz Pruszk |
| 22 Jan 22 |
r05 | | Opatija | 1 - 3 | Kustošija |
| 22 Jan 22 |
r05 | | Makedonija G | 1 - 0 | Spartak Varn |
| 22 Jan 22 |
r05 | | FC Levadia T | 2 - 0 | Tallinna JK |
| 22 Jan 22 |
r05 | | KuPS Kuopio | 5 - 1 | KTP |
| 22 Jan 22 |
r05 | | FA 2000 | 3 - 2 | Vanløse |
| 22 Jan 22 |
r05 | | Dynamo Brest | - | Neman Grodno |
| 22 Jan 22 |
r05 | | FC Homburg | 4 - 1 | UNA Strassen |
| 22 Jan 22 |
r05 | | HJK Helsinki | 3 - 0 | Ilves |
| 22 Jan 22 |
r05 | | Rot-Weiß Er | 1 - 1 | Hessen Kasse |
| 22 Jan 22 |
r05 | | Cobh Rambler | 0 - 5 | Waterford FC |
| 22 Jan 22 |
r05 | | Hamburg II | 3 - 3 | Eintracht No |
| 22 Jan 22 |
r05 | | Sirius | 2 - 1 | Oerebro |
| 22 Jan 22 |
r05 | | Zurich | 1 - 0 | FC Wil |
| 22 Jan 22 |
r05 | | Zenit St Pet | 2 - 2 | Botev Plovdi |
| 22 Jan 22 |
r05 | | Wisla Krakow | - | Makedonija G |
| 22 Jan 22 |
r05 | | Slaven Belup | 1 - 0 | NK Inter Zap |
| 22 Jan 22 |
r05 | | Nurnberg II | 0 - 1 | Sonnenhof Gr |
| 22 Jan 22 |
r05 | | FC Schweinfu | 8 - 0 | Bayern Alzen |
| 22 Jan 22 |
r05 | | Rielasingen- | 0 - 1 | TSG Balingen |
| 22 Jan 22 |
r05 | | SV Josko Rie | 6 - 0 | Lask Juniors |
| 22 Jan 22 |
r05 | | Phönix Lüb | - | Todesfelde |
| 22 Jan 22 |
r05 | | Paksi FC | - | Pécs |
| 22 Jan 22 |
r05 | | Olimpija Lju | 2 - 3 | Szombathelyi |
| 22 Jan 22 |
r05 | | FC Lviv | 0 - 0 | TSV Hartberg |
| 22 Jan 22 |
r05 | | FV Illertiss | 1 - 2 | FC Memmingen |
| 22 Jan 22 |
r05 | | KPV | 1 - 5 | VPS |
| 22 Jan 22 |
r05 | | FC Krasnodar | 5 - 2 | Hebar Pazard |
| 22 Jan 22 |
r05 | | FC Nordsjæl | 1 - 2 | Viborg |
| 22 Jan 22 |
r05 | | Lucerne | 2 - 2 | SC Rheindorf |
| 22 Jan 22 |
r05 | | Lugano | 1 - 0 | Chiasso |
| 22 Jan 22 |
r05 | | Vaduz | 4 - 0 | Austria Lust |
| 22 Jan 22 |
r05 | | Paris FC | 3 - 4 | Niort |
| 22 Jan 22 |
r05 | | Žarkovo | 2 - 1 | NK Lokomotiv |
| 22 Jan 22 |
r05 | | LASK | 1 - 2 | NK Maribor |
| 22 Jan 22 |
r05 | | FC Liefering | 2 - 3 | First Vienna |
| 22 Jan 22 |
r05 | | FC Basel | 3 - 1 | Neuchâtel X |
| 22 Jan 22 |
r05 | | Lechia Gdań | 2 - 1 | Terek Grozny |
| 22 Jan 22 |
r05 | | Chornomorets | 4 - 0 | FC Prishtina |
| 22 Jan 22 |
r05 | | Cukaricki | 1 - 0 | PFC Kuban Kr |
| 22 Jan 22 |
r05 | | Drogheda | 1 - 1 | Derry City |
| 22 Jan 22 |
r05 | | Gornik Zabrz | 2 - 1 | Baltika Kali |
| 22 Jan 22 |
r05 | | Nieciecza | 2 - 0 | Kolubara |
| 22 Jan 22 |
r05 | | Teplice | 2 - 1 | Rapid Vienna |
| 22 Jan 22 |
r05 | | Jablonec | - | FK Rostov |
| 22 Jan 22 |
r05 | | Lech Poznan | 4 - 1 | NŠ Mura |
| 22 Jan 22 |
r05 | | Krylya Sovet | 1 - 1 | Celje |
| 22 Jan 22 |
r05 | | Jeunesse Esc | 1 - 1 | Swift Hesper |
| 22 Jan 22 |
r05 | | FC Aarau | 9 - 0 | Bellinzona |
| 22 Jan 22 |
r05 | | Dynamo Kiev | 4 - 0 | Racing FC Un |
| 22 Jan 22 |
r05 | | Treaty Unite | 0 - 2 | Finn Harps F |
| 22 Jan 22 |
r05 | | CD Nacional | 0 - 0 | Peñarol |
| 23 Jan 22 |
r05 | | Sarmiento | - | Santiago Wan |
| 23 Jan 22 |
r05 | | FK Rubin Kaz | 0 - 0 | Wisla Plock |
| 23 Jan 22 |
r05 | | Fakel Vorone | 0 - 0 | Nizhny Novgo |
| 23 Jan 22 |
r05 | | Phnom Penh C | 3 - 0 | Kirivong Sok |
| 23 Jan 22 |
r05 | | Tomsk | 2 - 2 | FC Forte Tag |
| 23 Jan 22 |
r05 | | Fredericia | 6 - 0 | Næsby |
| 23 Jan 22 |
r05 | | Silkeborg IF | - | Raufoss |
| 23 Jan 22 |
r05 | | FC Krasnodar | 3 - 2 | MSK Zilina |
| 23 Jan 22 |
r05 | | Rakow Czesto | - | Rabotnichki |
| 23 Jan 22 |
r05 | | Soroksár | - | Diosgyor |
| 23 Jan 22 |
r05 | | SV Heimstett | 0 - 2 | Aalen |
| 23 Jan 22 |
r05 | | Warta Pozna� | 1 - 3 | Shkendija 79 |
| 23 Jan 22 |
r05 | | Piast Gliwic | 1 - 1 | Radnički Ni |
| 23 Jan 22 |
r05 | | Videoton FC | - | Gyirmót |
| 23 Jan 22 |
r05 | | Diosgyor | 2 - 2 | Kosice |
| 23 Jan 22 |
r05 | | Dinamo Zagre | 4 - 3 | Sturm Graz |
| 23 Jan 22 |
r05 | | TSV Rain am | 1 - 3 | Schwaben Aug |
| 23 Jan 22 |
r05 | | Schaffhausen | 1 - 3 | St. Gallen |
| 23 Jan 22 |
r05 | | Zorya | 2 - 2 | Aktobe |
| 23 Jan 22 |
r05 | | FC Olexandri | 1 - 2 | Zaglebie Lub |
| 23 Jan 22 |
r05 | | Gazovik Oren | 1 - 4 | FC Ufa |
| 23 Jan 22 |
r05 | | Chayka Pesch | 1 - 0 | Gjilani |
| 23 Jan 22 |
r05 | | Nomme Kalju | 5 - 0 | Trans Narva |
| 23 Jan 22 |
r05 | | Wisla Plock | 2 - 2 | Radnički 19 |
| 23 Jan 22 |
r05 | | Lechia Gdań | - | Dinamo Batum |
| 23 Jan 22 |
r05 | | Novi Pazar | 1 - 1 | Akademija Pa |
| 23 Jan 22 |
r05 | | Orlando City | - | New York Cit |
| 23 Jan 22 |
r05 | | Royal Pari | 3 - 1 | Real Santa C |
| 23 Jan 22 |
r05 | | Blooming | 1 - 2 | Oriente Petr |
| 24 Jan 22 |
r05 | | Krylya Sovet | 2 - 0 | Radnik Surdu |
| 24 Jan 22 |
r05 | | Prey Veng | 3 - 1 | Boeung Ket |
| 24 Jan 22 |
r05 | | Cibalia | 0 - 1 | Iskra Danilo |
| 24 Jan 22 |
r05 | | CSKA Moscow | 0 - 1 | F91 Dudelang |
| 24 Jan 22 |
r05 | | FC Copenhage | 3 - 2 | FC Helsingoe |
| 24 Jan 22 |
r05 | | FC Metalist | - | Liberec |
| 24 Jan 22 |
r05 | | FC Astana | - | TSC Bačka T |
| 24 Jan 22 |
r05 | | Tatran Lipto | - | FC Lviv |
| 24 Jan 22 |
r05 | | Austria Vien | - | Bohemians |
| 24 Jan 22 |
r05 | | Zira FK | 1 - 1 | Bregalnica � |
| 24 Jan 22 |
r05 | | Hradec Král | 1 - 1 | Veres Rivne |
| 24 Jan 22 |
r05 | | Metallurg Li | 0 - 0 | FC SKA Rosto |
| 24 Jan 22 |
r05 | | Wolfsberger | 1 - 4 | Shakhtar Don |
| 24 Jan 22 |
r05 | | Dynamo Česk | 4 - 2 | Khimki FK |
| 24 Jan 22 |
r05 | | CD Nacional | 1 - 0 | Sarmiento |
| 24 Jan 22 |
r05 | | Danubio | 0 - 1 | Barracas Cen |
| 25 Jan 22 |
r05 | | Peñarol | 2 - 0 | Santiago Wan |
| 25 Jan 22 |
r05 | | Zenit St Pet | 5 - 0 | MSK Zilina |
| 25 Jan 22 |
r05 | | Shakhter Kar | - | Gjilani |
| 25 Jan 22 |
r05 | | PFC Kuban Kr | - | Olimp-Dolgop |
| 25 Jan 22 |
r05 | | Dubnica | 1 - 1 | Třinec |
| 25 Jan 22 |
r05 | | Odra Opole | 2 - 2 | Chojniczanka |
| 25 Jan 22 |
r05 | | Tatran Lipto | - | Qarabag FK |
| 25 Jan 22 |
r05 | | Austria Vien | 0 - 0 | PFC Sochi |
| 25 Jan 22 |
r05 | | Lokomotiv So | 1 - 1 | Dukagjini |
| 25 Jan 22 |
r05 | | Riga FC | 2 - 1 | Slovan Brati |
| 25 Jan 22 |
r05 | | Skive IK | 0 - 5 | Randers FC |
| 25 Jan 22 |
r05 | | Slavia Sofia | 1 - 2 | Teplice |
| 25 Jan 22 |
r05 | | Partizan Bel | 2 - 1 | Tikveš |
| 25 Jan 22 |
r05 | | Dundalk | 1 - 5 | Bohemians |
| 25 Jan 22 |
r05 | | Mlada Bolesl | 2 - 2 | Dukla Praha |
| 25 Jan 22 |
r05 | | Randers FC | - | Raufoss |
| 25 Jan 22 |
r05 | | Hajduk Split | 4 - 2 | NK Varaždin |
| 25 Jan 22 |
r05 | | Olimpija Lju | 3 - 0 | Slovacko |
| 25 Jan 22 |
r05 | | Beroe | 1 - 3 | Gazovik Oren |
| 25 Jan 22 |
r05 | | Akron Tolyat | 2 - 1 | Proleter Nov |
| 25 Jan 22 |
r05 | | Celje | 1 - 0 | PFC Kuban Kr |
| 25 Jan 22 |
r05 | | NK Maribor | 1 - 1 | Crvena Zvezd |
| 25 Jan 22 |
r05 | | Esbjerg | 2 - 0 | Thisted |
| 25 Jan 22 |
r05 | | Murcia | 1 - 3 | Dynamo Kiev |
| 25 Jan 22 |
r05 | | Lyseng | 1 - 0 | Aarhus Frema |
| 25 Jan 22 |
r05 | | VfR Garching | 2 - 1 | TSV Buchbach |
| 25 Jan 22 |
r05 | | Jeunesse Esc | 1 - 1 | Mondorf-les- |
| 25 Jan 22 |
r05 | | Derry City | 5 - 0 | Institute |
| 25 Jan 22 |
r05 | | Liverpool Mo | 0 - 2 | Instituto AC |
| 26 Jan 22 |
r05 | | CSKA Sofia | - | TSV Hartberg |
| 26 Jan 22 |
r05 | | Visakha | 3 - 2 | Boeung Ket |
| 26 Jan 22 |
r05 | | Metalist Kha | 1 - 1 | Radomiak Rad |
| 26 Jan 22 |
r05 | | Podbeskidzie | 2 - 2 | GKS Katowice |
| 26 Jan 22 |
r05 | | NK Maribor | 1 - 2 | Voždovac |
| 26 Jan 22 |
r05 | | Arka Gdynia | 1 - 0 | Olimpia Grud |
| 26 Jan 22 |
r05 | | Floridsdorfe | - | ŠKF Sereď |
| 26 Jan 22 |
r05 | | Trans Narva | - | Maardu Linna |
| 26 Jan 22 |
r05 | | FC Anzhi Mak | 6 - 1 | PFC Dynamo S |
| 26 Jan 22 |
r05 | | Koper | 0 - 2 | Rudar Prijed |
| 26 Jan 22 |
r05 | | MFK Ružombe | 2 - 1 | Radnički Ni |
| 26 Jan 22 |
r05 | | Spartak Subo | 0 - 2 | Karvina |
| 26 Jan 22 |
r05 | | Strumska Sla | 0 - 2 | Sportist Svo |
| 26 Jan 22 |
r05 | | Teteks | 4 - 3 | Skopje |
| 26 Jan 22 |
r05 | | Vejle Boldkl | - | Esbjerg |
| 26 Jan 22 |
r05 | | Wanderers | 3 - 1 | Albion FC |
| 26 Jan 22 |
r05 | | Wisla Krakow | - | Rabotnichki |
| 26 Jan 22 |
r05 | | Ural S.R | 1 - 1 | Pyunik Yerev |
| 26 Jan 22 |
r05 | | Kazincbarcik | 1 - 2 | Kosice |
| 26 Jan 22 |
r05 | | Sesvete | 2 - 1 | Opatija |
| 26 Jan 22 |
r05 | | Siroki Brije | 0 - 3 | Velez Mostar |
| 26 Jan 22 |
r05 | | Zaglebie Lub | 3 - 1 | Metalac GM |
| 26 Jan 22 |
r05 | | FC Lviv | 0 - 0 | Dinamo Tbili |
| 26 Jan 22 |
r05 | | Cukaricki | 1 - 1 | NŠ Mura |
| 26 Jan 22 |
r05 | | Chornomorets | 1 - 1 | Shkupi |
| 26 Jan 22 |
r05 | | Gomel | 4 - 1 | FC Dnepr Mog |
| 26 Jan 22 |
r05 | | FC Prishtina | 2 - 2 | Atyrau |
| 26 Jan 22 |
r05 | | Jablonec | - | Bodoe/Glimt |
| 26 Jan 22 |
r05 | | Gornik Zabrz | 2 - 2 | FC Olexandri |
| 26 Jan 22 |
r05 | | Korona Kielc | 1 - 0 | Skra Często |
| 26 Jan 22 |
r05 | | Sparta Pragu | 2 - 3 | Lok. Moscow |
| 26 Jan 22 |
r05 | | Union Berlin | - | Aue |
| 26 Jan 22 |
r05 | | Dubrava | 3 - 2 | Kustošija |
| 26 Jan 22 |
r05 | | Rijeka | 3 - 0 | Triglav Kran |
| 26 Jan 22 |
r05 | | Slask Wrocla | 0 - 2 | Vojvodina |
| 26 Jan 22 |
r05 | | FV Illertiss | 0 - 2 | Aalen |
| 26 Jan 22 |
r05 | | UT Pétange | 2 - 2 | FC 03 Differ |
| 26 Jan 22 |
r05 | | Athlone Town | 1 - 2 | Sligo |
| 26 Jan 22 |
r05 | | Portuguesa | 0 - 1 | Monagas S.C. |
| 26 Jan 22 |
r05 | | Peñarol | 1 - 0 | CD Nacional |
| 26 Jan 22 |
r05 | | Club Univers | 1 - 2 | Real Tomayap |
| 26 Jan 22 |
r05 | | Metropolitan | 2 - 1 | Puerto Cabel |
| 27 Jan 22 |
r05 | | Estudiantes | 1 - 2 | San Lorenzo |
| 27 Jan 22 |
r05 | | Inter Miami | 4 - 0 | Universitari |
| 27 Jan 22 |
r05 | | Portland Tim | 0 - 0 | Seattle Soun |
| 27 Jan 22 |
r05 | | Saburtalo Tb | 0 - 0 | Sioni |
| 27 Jan 22 |
r05 | | Dynamo Kiev | 1 - 1 | Bodoe/Glimt |
| 27 Jan 22 |
r05 | | Karlsruhe | - | Elversberg |
| 27 Jan 22 |
r05 | | Osasuna | 0 - 1 | Alaves |
| 27 Jan 22 |
r05 | | Viking | 2 - 2 | Jablonec |
| 27 Jan 22 |
r05 | | Ludogorets R | 3 - 0 | Yantra Gabro |
| 27 Jan 22 |
r05 | | SC Cambuur | 0 - 1 | SC Heracles |
| 27 Jan 22 |
r05 | | DAC 1904 Dun | 1 - 1 | TSC Bačka T |
| 27 Jan 22 |
r05 | | FC Koln | 2 - 2 | Schalke 04 |
| 27 Jan 22 |
r05 | | Jablonec | - | FK Rostov |
| 27 Jan 22 |
r05 | | Metalist Kha | 0 - 0 | Warta Pozna� |
| 27 Jan 22 |
r05 | | Silkeborg IF | 2 - 0 | Odense BK |
| 27 Jan 22 |
r05 | | FK Aksu | - | Bregalnica � |
| 27 Jan 22 |
r05 | | Lokomotiv Pl | 0 - 0 | Etar Veliko |
| 27 Jan 22 |
r05 | | Vejle Boldkl | 1 - 1 | Jagiellonia |
| 27 Jan 22 |
r05 | | Llapi | 2 - 0 | Akademija Pa |
| 27 Jan 22 |
r05 | | Wolfsberger | 1 - 1 | Bohemians |
| 27 Jan 22 |
r05 | | Augsburg | 3 - 3 | Jahn Regensb |
| 27 Jan 22 |
r05 | | Bochum | 0 - 2 | Fortuna Düs |
| 27 Jan 22 |
r05 | | Mainz | 0 - 1 | Ein Frankfur |
| 27 Jan 22 |
r05 | | Nurnberg | 9 - 0 | Pribram |
| 27 Jan 22 |
r05 | | FC Olexandri | 0 - 1 | Ballkani |
| 27 Jan 22 |
r05 | | Piast Gliwic | 3 - 0 | Arda Kardzha |
| 27 Jan 22 |
r05 | | Rakow Czesto | 3 - 2 | Zorya |
| 27 Jan 22 |
r05 | | Stal Mielec | - | Makedonija G |
| 27 Jan 22 |
r05 | | Nieciecza | 1 - 1 | Radnik Surdu |
| 27 Jan 22 |
r05 | | Molde | 1 - 0 | F91 Dudelang |
| 27 Jan 22 |
r05 | | Ludogorets R | 2 - 1 | Wisla Plock |
| 27 Jan 22 |
r05 | | Gornik Leczn | 0 - 0 | Novi Pazar |
| 27 Jan 22 |
r05 | | Liberec | 3 - 1 | Shkendija 79 |
| 27 Jan 22 |
r05 | | AIK | 1 - 2 | Sollentuna |
| 27 Jan 22 |
r05 | | Hacken | 2 - 3 | Fredrikstad |
| 27 Jan 22 |
r05 | | Royal Pari | 1 - 1 | Real Santa C |
| 28 Jan 22 |
r05 | | Peresvet Pod | 1 - 2 | Saturn Ramen |
| 28 Jan 22 |
r05 | | Arka Gdynia | 0 - 2 | Odra Opole |
| 28 Jan 22 |
r05 | | Peninsula Po | 3 - 2 | Newcastle Ol |
| 28 Jan 22 |
r05 | | Dynamo Česk | - | Cracovia Kra |
| 28 Jan 22 |
r05 | | FK Rostov | 1 - 2 | Stuttgart |
| 28 Jan 22 |
r05 | | Galatasaray | 2 - 6 | Tuzlaspor |
| 28 Jan 22 |
r05 | | Hamburg | 1 - 5 | FC Midtjylla |
| 28 Jan 22 |
r05 | | Perth SC | 3 - 1 | Balcatta FC |
| 28 Jan 22 |
r05 | | Perth Glory | 1 - 0 | Gwelup Croat |
| 28 Jan 22 |
r05 | | Randers FC | - | Elfsborg |
| 28 Jan 22 |
r05 | | Zaglebie Sos | 1 - 1 | Sandecja Now |
| 28 Jan 22 |
r05 | | Domzale | 3 - 1 | Slovacko |
| 28 Jan 22 |
r05 | | Austria Vien | 3 - 1 | Hradec Král |
| 28 Jan 22 |
r05 | | Dynamo Brest | 0 - 1 | Neman Grodno |
| 28 Jan 22 |
r05 | | Polissya Zhy | - | Vardar |
| 28 Jan 22 |
r05 | | Riga FC | 2 - 1 | MSK Zilina |
| 28 Jan 22 |
r05 | | Legia Warsaw | 4 - 0 | Tychy 71 |
| 28 Jan 22 |
r05 | | Widzew Lodz | 1 - 0 | Ruch Chorzow |
| 28 Jan 22 |
r05 | | Dynamo Dresd | - | Mlada Bolesl |
| 28 Jan 22 |
r05 | | ECU Joondalu | 3 - 2 | Bayswater Ci |
| 28 Jan 22 |
r05 | | Brøndby | 2 - 1 | Viborg |
| 28 Jan 22 |
r05 | | SV Josko Rie | 5 - 2 | SKU Amstette |
| 28 Jan 22 |
r05 | | Spartak Mosc | 2 - 2 | Slovan Brati |
| 28 Jan 22 |
r05 | | Beroe | 1 - 2 | SC Dnipro-1 |
| 28 Jan 22 |
r05 | | Teplice | 1 - 1 | FC Lviv |
| 28 Jan 22 |
r05 | | Austria Vien | 3 - 1 | Lask Juniors |
| 28 Jan 22 |
r05 | | Bourg-Peronn | 3 - 0 | Grenoble |
| 28 Jan 22 |
r05 | | CSKA Sofia | 3 - 1 | Dinamo Mosco |
| 28 Jan 22 |
r05 | | Djurgaarden | - | METTA Latvij |
| 28 Jan 22 |
r05 | | SV Lafnitz | - | TSV Hartberg |
| 28 Jan 22 |
r05 | | Shakhtar Don | - | Shakhter Sol |
| 28 Jan 22 |
r05 | | Bayern Munic | 0 - 2 | SSV Ulm |
| 28 Jan 22 |
r05 | | Metallurg Li | 0 - 2 | Chayka Pesch |
| 28 Jan 22 |
r05 | | Malmo FF | 2 - 2 | Jammerbugt |
| 28 Jan 22 |
r05 | | FK Haugesund | 1 - 1 | ASANE FOTBAL |
| 28 Jan 22 |
r05 | | Valencia Mes | 2 - 1 | FC Liefering |
| 28 Jan 22 |
r05 | | Galway Unite | 2 - 0 | St Patricks |
| 28 Jan 22 |
r05 | | Tatran Lipto | - | Spartak Subo |
| 28 Jan 22 |
r05 | | Fremad Amage | 0 - 0 | Roskilde |
| 28 Jan 22 |
r05 | | Wiener Neust | 2 - 0 | SV Horn |
| 28 Jan 22 |
r05 | | Vendsyssel F | 3 - 2 | Aarhus Frema |
| 28 Jan 22 |
r05 | | Køge | 1 - 2 | Hillerød |
| 28 Jan 22 |
r05 | | FC Helsingoe | 5 - 2 | AB Gladsaxe |
| 28 Jan 22 |
r05 | | Bohemians | 1 - 0 | Bray Wandere |
| 29 Jan 22 |
r05 | | Bełchatów | - | Arka Gdynia |
| 29 Jan 22 |
r05 | | Kolding IF | 2 - 3 | Fredericia |
| 29 Jan 22 |
r05 | | Viktoria Plz | - | ŠKF Sereď |
| 29 Jan 22 |
r05 | | Vlašim | 5 - 2 | Vysočina Ji |
| 29 Jan 22 |
r05 | | Zlín | 4 - 0 | FK Senica |
| 29 Jan 22 |
r05 | | Lyngby | 3 - 3 | Hvidovre IF |
| 29 Jan 22 |
r05 | | AGF Aarhus | 7 - 0 | Esbjerg |
| 29 Jan 22 |
r05 | | Gomel | - | Slavia Mozyr |
| 29 Jan 22 |
r05 | | First Vienna | - | Líšeň |
| 29 Jan 22 |
r05 | | Gornik Zabrz | 1 - 1 | Podbeskidzie |
| 29 Jan 22 |
r05 | | Frem | 2 - 1 | Hellerup IK |
| 29 Jan 22 |
r05 | | HOBRO | 2 - 0 | Thisted |
| 29 Jan 22 |
r05 | | Nykøbing | 0 - 1 | Næstved BK |
| 29 Jan 22 |
r05 | | Landskrona | 3 - 0 | IFK Malmö |
| 29 Jan 22 |
r05 | | FC Copenhage | 3 - 0 | FC Flora Tal |
| 29 Jan 22 |
r05 | | VfR Garching | 0 - 2 | 1860 Rosenhe |
| 29 Jan 22 |
r05 | | Halmstad | 0 - 1 | Varbergs BoI |
| 29 Jan 22 |
r05 | | Holbæk B&I | 1 - 1 | Slagelse B&I |
| 29 Jan 22 |
r05 | | Legia Warsaw | 4 - 0 | Radomiak Rad |
| 29 Jan 22 |
r05 | | Norrby | 1 - 2 | Utsiktens BK |
| 29 Jan 22 |
r05 | | MFK Ružombe | 1 - 2 | Ballkani |
| 29 Jan 22 |
r05 | | Skra Często | 2 - 1 | Stal Stalowa |
| 29 Jan 22 |
r05 | | Honka | 0 - 1 | Paide Linnam |
| 29 Jan 22 |
r05 | | FC Schweinfu | 1 - 4 | Kickers Offe |
| 29 Jan 22 |
r05 | | Sirius | 1 - 3 | Hammarby |
| 29 Jan 22 |
r05 | | Veres Rivne | 3 - 4 | Karvina |
| 29 Jan 22 |
r05 | | Miedz Legnic | 0 - 0 | Lech Poznan |
| 29 Jan 22 |
r05 | | Hannover II | 2 - 3 | Holstein Kie |
| 29 Jan 22 |
r05 | | Pardubice | 4 - 1 | Dukla Praha |
| 29 Jan 22 |
r05 | | Baltika Kali | 0 - 1 | PFC Sochi |
| 29 Jan 22 |
r05 | | Alania Vladi | 0 - 0 | Cukaricki |
| 29 Jan 22 |
r05 | | SV Salzburg | - | WSG Swarovsk |
| 29 Jan 22 |
r05 | | Waterford FC | 2 - 1 | Dundalk |
| 29 Jan 22 |
r05 | | FC Tobol | 0 - 3 | Bregalnica � |
| 29 Jan 22 |
r05 | | DAC 1904 Dun | 0 - 1 | PFC Kuban Kr |
| 29 Jan 22 |
r05 | | FC Trenkwald | 2 - 3 | FC BW Linz |
| 29 Jan 22 |
r05 | | Cork City FC | 1 - 1 | Finn Harps F |
| 29 Jan 22 |
r05 | | Levski Sofia | 2 - 2 | NK Maribor |
| 29 Jan 22 |
r05 | | New England | 1 - 1 | Los Angeles |
| 29 Jan 22 |
r05 | | Sporting Kan | 0 - 0 | Colorado Rap |
| 30 Jan 22 |
r05 | | Makedonija G | 0 - 0 | SC Rheindorf |
| 30 Jan 22 |
r05 | | Metalac GM | 1 - 0 | Sileks |
| 30 Jan 22 |
r05 | | Slavia Pragu | 4 - 2 | Banik Ostrav |
| 30 Jan 22 |
r05 | | Slavia Sofia | 3 - 2 | NŠ Mura |
| 30 Jan 22 |
r05 | | Krylya Sovet | 0 - 0 | Akademija Pa |
| 31 Jan 22 |
r05 | | Shakhter Kar | 1 - 5 | CSKA Sofia |
| 31 Jan 22 |
r05 | | Borac Banja | - | Shakhter Sol |
| 31 Jan 22 |
r05 | | LKS Lodz | 1 - 1 | Rudar Pljevl |
| 31 Jan 22 |
r05 | | Metallurg Li | 1 - 1 | Csikszereda |
| 31 Jan 22 |
r05 | | FC Nordsjæl | 3 - 0 | IFK Gothenbu |
| 31 Jan 22 |
r05 | | Terek Grozny | 2 - 2 | Shkupi |
| 31 Jan 22 |
r05 | | DAC 1904 Dun | 0 - 2 | Cukaricki |
| 31 Jan 22 |
r05 | | Shakhtar Don | 3 - 2 | Crvena Zvezd |
| 31 Jan 22 |
r05 | | FC Olexandri | 3 - 0 | Vejle Boldkl |
| 01 Feb 22 |
r05 | | Torpedo Mosc | 4 - 1 | Sileks |
| 01 Feb 22 |
r05 | | Vysočina Ji | 3 - 3 | Chrudim |
| 01 Feb 22 |
r05 | | Ararat-Armen | 2 - 3 | Slovan Brati |
| 01 Feb 22 |
r05 | | FC SKA Rosto | 0 - 2 | Vardar |
| 01 Feb 22 |
r05 | | MFK Ružombe | 2 - 1 | Dinamo Mosco |
| 01 Feb 22 |
r05 | | Velez Mostar | 3 - 0 | GOŠK Gabela |
| 02 Feb 22 |
r05 | | Tychy 71 | 2 - 2 | Jastrzębie |
| 02 Feb 22 |
r05 | | Zaglebie Sos | - | Aktobe |
| 02 Feb 22 |
r05 | | Slavoj Vyše | 1 - 6 | Varnsdorf |
| 02 Feb 22 |
r05 | | FC Liefering | 2 - 1 | Villarreal B |
| 02 Feb 22 |
r05 | | Mariupol | P - P | Siroki Brije |
| 02 Feb 22 |
r05 | | Brabrand IF | 1 - 2 | Aarhus Frema |
| 02 Feb 22 |
r05 | | Raufoss | 2 - 2 | Skeid |
| 03 Feb 22 |
r05 | | Montana | - | Sileks |
| 03 Feb 22 |
r05 | | Slavia Sofia | - | Vojvodina |
| 03 Feb 22 |
r05 | | Hacken | 0 - 0 | FK Rostov |
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