15 Jan 22 | r06 | Akwa United | 2 - 0 | Katsina Unit |
16 Jan 22 | r06 | Gombe United | 0 - 0 | Enyimba |
16 Jan 22 | r06 | Abia Warrior | 1 - 0 | Heartland |
16 Jan 22 | r06 | Plateau Unit | 5 - 0 | Dakkada |
16 Jan 22 | r06 | Shooting Sta | 2 - 2 | Sunshine Sta |
16 Jan 22 | r06 | Rivers Unite | 3 - 0 | Kwara United |
16 Jan 22 | r06 | Nasarawa Uni | 2 - 1 | Lobi Stars |
16 Jan 22 | r06 | Kano Pillars | 1 - 0 | Niger Tornad |
16 Jan 22 | r06 | Wikki Touris | 1 - 2 | Remo Stars |
16 Jan 22 | r06 | Rangers Inte | 2 - 0 | MFM |