18 Sep 21 | r53 | Melilla | 1 - 3 | Recreativo G |
18 Sep 21 | r53 | Hercules | 2 - 1 | Mar Menor |
19 Sep 21 | r53 | Murcia | 2 - 0 | CF Intercity |
19 Sep 21 | r53 | La Nucía | 0 - 0 | Socuéllamos |
19 Sep 21 | r53 | El Ejido | 0 - 1 | CA Pulpileñ |
19 Sep 21 | r53 | Mancha Real | 2 - 0 | CD Toledo |
19 Sep 21 | r53 | Águilas | 2 - 0 | CD Marchamal |
19 Sep 21 | r53 | Eldense | 1 - 1 | Alzira |
19 Sep 21 | r53 | Calvo Sotelo | 0 - 0 | Atlético Le |