11 Feb 22 | r22 | Flambeau de | 1 - 0 | Les Crocos |
12 Feb 22 | r22 | Bujumbura Ci | 1 - 4 | Olympic Star |
12 Feb 22 | r22 | Rukinzo | 1 - 1 | Athlético O |
13 Feb 22 | r22 | Le Messager | 0 - 0 | Musongati FC |
13 Feb 22 | r22 | BS Dynamik | 1 - 0 | VitalO |
13 Feb 22 | r22 | Aigle Noir | 2 - 0 | Royal de Mur |
13 Feb 22 | r22 | Bumamuru | 0 - 0 | Top Junior |
13 Feb 22 | r22 | Kayanza Unit | 2 - 0 | Flambeau du |