11 Sep 21 | r01 | Borussia Dor | 25 - 25 | Ferencváros |
11 Sep 21 | r01 | Rostov-Don W | 26 - 24 | Brest Bretag |
11 Sep 21 | r01 | Győri Audi | 35 - 29 | Vipers Krist |
11 Sep 21 | r01 | RK Podravka | 29 - 22 | ŽRK Budućn |
12 Sep 21 | r01 | Team Esbjerg | 22 - 21 | CSM Bucureș |
12 Sep 21 | r01 | IK Sävehof | 29 - 28 | RK Krim Wome |
12 Sep 21 | r01 | Kastamonu Bl | 25 - 31 | Odense Hånd |
17 Nov 21 | r01 | Metz Handbal | 24 - 32 | HBC CSKA Mos |