Alessandro De Vitis (born 15 February 1992) is an Italian footballer, who plays as a midfielder for Pisa. His father is the Italian striker Antonio De Vitis.
On 21 August 2009, De Vitis moved from Fiorentina to Parma on a permanent deal. He played two seasons with Parma's youth team before he was loaned to Serie B side Modena in the summer of 2011. He made 24 league appearances in the 42-match season, but completed 90 minutes just twice and 14 of the 24 were from the bench.
The following year, he was loaned out to a Serie B side with better promotion prospects: Padova.
On 31 July 2013 De Vitis was signed by fellow Serie A club U.C. Sampdoria for €2.3 million in a 5-year contract, with Gianni Munari moved to opposite direction for €500,000.
On 2 August 2013 De Vitis was signed by Carpi F.C. 1909. On 7 August 2015 he was signed by SPAL.
De Vitis has represented his country at international level for the under-16, under-17, under-18, under-19 and under-20 sides.