Lisanne de Witte (born 10 September 1992) is a Dutch sprinter. She competed in the 2016 Summer Olympics in Rio de Janeiro on the Dutch 4 × 400 m relay team who ran a national record of 3:26.98. She also competed in the 400 metres event at the 2014 IAAF World Indoor Championships. She ran a personal best of 52.61 s in the series and came in third in the semifinals, but was excluded from the finals after the US team argued that she had impeded Joanna Atkins, who came in fourth behind her. At the 2018 European Championships she won the bronze medal.
Her younger sister, Laura de Witte, is also a 400 metres sprinter.