Afran Ismayilov (Azerbaijani: Əfran İsmayılov, born on 8 October 1988 in Baku, Azerbaijan SSR) is an Azerbaijani football midfielder who plays for Azerbaijan Premier League side Sabail.
Ismayilov is a part of the Azerbaijan U-21 side that is competing in the 2011 European Under-21 Championship qualification.
In 2010, he was called up for the Azerbaijan national football team and scored his first goal on his debut in friendly match against Jordan national football team in Amman.