08 Jan 22 | r17 | OFI | 1 - 1 | Giannina |
09 Jan 22 | r17 | NFC Volos | 3 - 1 | Panathinaiko |
16 Feb 22 | r17 | Panetolikos | 1 - 0 | Lamia |
23 Feb 22 | r17 | Aris | 3 - 0 | Atromitos |
23 Feb 22 | r17 | Ionikos | 4 - 0 | Apollon Smir |
02 Mar 22 | r17 | Olympiakos | 5 - 1 | Asteras Trip |
02 Mar 22 | r17 | AEK | 1 - 1 | PAOK |