15 Oct 21 | r11 | Club Brugge | 2 - 0 | Kortrijk |
16 Oct 21 | r11 | St. Gilloise | 4 - 2 | RFC Seraing |
16 Oct 21 | r11 | Waregem | 2 - 1 | Antwerp |
16 Oct 21 | r11 | KV Oostende | 2 - 1 | Cercle Brugg |
16 Oct 21 | r11 | Standard | 2 - 2 | Oud-Heverlee |
17 Oct 21 | r11 | St.Truiden | 2 - 2 | Anderlecht |
17 Oct 21 | r11 | Beerschot VA | 0 - 1 | Mechelen |
17 Oct 21 | r11 | Charleroi | 2 - 0 | Genk |
17 Oct 21 | r11 | Gent | 2 - 0 | Eupen |