17 Dec 21 | r20 | RFC Seraing | 0 - 2 | Kortrijk |
18 Dec 21 | r20 | Beerschot VA | 0 - 2 | KV Oostende |
18 Dec 21 | r20 | St. Gilloise | 3 - 2 | Cercle Brugg |
18 Dec 21 | r20 | Waregem | 3 - 2 | Mechelen |
18 Dec 21 | r20 | Gent | 2 - 1 | St.Truiden |
19 Dec 21 | r20 | Club Brugge | 2 - 2 | Anderlecht |
19 Dec 21 | r20 | Eupen | 0 - 4 | Charleroi |
19 Dec 21 | r20 | Genk | 1 - 1 | Antwerp |
19 Dec 21 | r20 | Oud-Heverlee | 2 - 1 | Standard |