11 Feb 22 | r27 | RFC Seraing | 0 - 1 | Antwerp |
12 Feb 22 | r27 | Eupen | 0 - 1 | Gent |
12 Feb 22 | r27 | Oud-Heverlee | 3 - 2 | Cercle Brugg |
12 Feb 22 | r27 | Mechelen | 3 - 0 | KV Oostende |
12 Feb 22 | r27 | Waregem | 1 - 2 | Anderlecht |
13 Feb 22 | r27 | Genk | 2 - 0 | Standard |
13 Feb 22 | r27 | St. Gilloise | 0 - 1 | St.Truiden |
13 Feb 22 | r27 | Club Brugge | 2 - 0 | Charleroi |
13 Feb 22 | r27 | Beerschot VA | 2 - 1 | Kortrijk |