30 Oct 21 | r13 | Mariupol | 2 - 3 | Dynamo Kiev |
30 Oct 21 | r13 | Shakhtar Don | 4 - 1 | Desna |
30 Oct 21 | r13 | Inhulets | 0 - 0 | Veres Rivne |
31 Oct 21 | r13 | FC Kolos Kov | 0 - 1 | FC Lviv |
31 Oct 21 | r13 | Rukh Lviv | 0 - 0 | FC Olexandri |
31 Oct 21 | r13 | FC Metalist | 1 - 6 | Zorya |
01 Nov 21 | r13 | SC Dnipro-1 | 4 - 0 | Mynai |
01 Nov 21 | r13 | Vorskla | 0 - 0 | Chornomorets |