22 Jan 22 | r18 | Pafos FC | 0 - 1 | Apollon Lima |
22 Jan 22 | r18 | AEL Limassol | 1 - 0 | Ethnikos Ach |
23 Jan 22 | r18 | Apoel Nicosi | 1 - 1 | Aris Limasso |
23 Jan 22 | r18 | Doxa Katokop | 0 - 0 | Olympiakos N |
24 Jan 22 | r18 | Omonia Nicos | 2 - 1 | PAEEK |
24 Jan 22 | r18 | AEK Larnaca | 1 - 1 | Anorthosis F |