09 Oct 21 | r10 | VVV-Venlo | 2 - 0 | MVV Maastric |
09 Oct 21 | r10 | FC Emmen | 0 - 1 | Excelsior |
09 Oct 21 | r10 | FC Eindhoven | 2 - 1 | TOP Oss |
10 Oct 21 | r10 | ADO Den Haag | 3 - 2 | FC Den Bosch |
10 Oct 21 | r10 | FC Dordrecht | 0 - 1 | Helmond Spor |
10 Oct 21 | r10 | Almere City | 1 - 2 | De Graafscha |
18 Oct 21 | r10 | Jong AZ | 1 - 1 | Jong Ajax |
18 Oct 21 | r10 | Jong PSV | 2 - 3 | SC Telstar |
18 Oct 21 | r10 | Jong Utrecht | 1 - 2 | Roda JC |
18 Oct 21 | r10 | FC Volendam | 1 - 0 | NAC Breda |