07 Mar 22 | r30 | Jong AZ | 3 - 2 | SC Telstar |
11 Mar 22 | r30 | Almere City | 3 - 0 | Helmond Spor |
11 Mar 22 | r30 | FC Den Bosch | 3 - 1 | MVV Maastric |
11 Mar 22 | r30 | FC Dordrecht | 3 - 3 | Jong Ajax |
11 Mar 22 | r30 | FC Eindhoven | 4 - 0 | VVV-Venlo |
11 Mar 22 | r30 | FC Emmen | 2 - 0 | Jong Utrecht |
11 Mar 22 | r30 | NAC Breda | 2 - 0 | De Graafscha |
11 Mar 22 | r30 | TOP Oss | 1 - 2 | Roda JC |
11 Mar 22 | r30 | FC Volendam | 2 - 5 | Excelsior |
19 Apr 22 | r30 | ADO Den Haag | 2 - 2 | Jong PSV |