13 Sep 21 | Quarter-Final | Esteghlal | 0 - 2 | Al Hilal |
14 Sep 21 | Quarter-Final | Nagoya Gramp | 4 - 2 | Daegu FC |
14 Sep 21 | Quarter-Final | Ulsan Hyunda | 0 - 0 | Kawasaki Fro |
14 Sep 21 | Quarter-Final | Istiklol | 0 - 1 | Persepolis |
14 Sep 21 | Quarter-Final | Al Nassr FC | 1 - 0 | Tractor Sazi |
14 Sep 21 | Quarter-Final | Al Sharjah | 1 - 1 | Al Wahda |
15 Sep 21 | Quarter-Final | Jeonbuk Hyun | 1 - 1 | BG Pathum Un |
15 Sep 21 | Quarter-Final | Cerezo Osaka | 0 - 1 | Pohang Steel |