20 Apr 21 | r01 | Metropolitan | 2 - 3 | FBC Melgar |
20 Apr 21 | r01 | Atletico GO | 0 - 0 | Newells Old |
21 Apr 21 | r01 | 12 de Octubr | 1 - 0 | Rosario Cent |
21 Apr 21 | r01 | SD Aucas | 0 - 1 | Atletico PR |
21 Apr 21 | r01 | San Lorenzo | 0 - 1 | Huachipato |
21 Apr 21 | r01 | Ceara | 3 - 1 | Wilstermann |
22 Apr 21 | r01 | Montevideo C | 1 - 1 | Bahia |
22 Apr 21 | r01 | Club Deporti | 1 - 3 | Independient |
22 Apr 21 | r01 | Talleres de | 1 - 2 | Emelec |
22 Apr 21 | r01 | Bolivar | 2 - 1 | Arsenal Sara |
22 Apr 21 | r01 | Bragantino | 2 - 1 | Deportes Tol |
22 Apr 21 | r01 | Gremio | 2 - 1 | La Equidad |
22 Apr 21 | r01 | Aragua F.C. | 0 - 1 | Lanus |
23 Apr 21 | r01 | Peñarol | 5 - 1 | Sport Huanca |
23 Apr 21 | r01 | Club River P | 0 - 0 | Corinthians |
23 Apr 21 | r01 | Club Liberta | 2 - 0 | Palestino |