12 Apr 22 | r02 | Real Esppor | 0 - 2 | Ceara |
12 Apr 22 | r02 | Oriente Petr | 1 - 3 | Union |
13 Apr 22 | r02 | Defensa y Ju | 0 - 1 | Atletico GO |
13 Apr 22 | r02 | LDU Quito | 4 - 0 | Deportes Ant |
13 Apr 22 | r02 | Independient | 2 - 0 | General Caba |
13 Apr 22 | r02 | FBC Melgar | 2 - 0 | CA River Pla |
13 Apr 22 | r02 | Santos FC | 3 - 2 | Universidad |
13 Apr 22 | r02 | Racing Club | 2 - 0 | Cuiaba |
14 Apr 22 | r02 | Wilstermann | 0 - 2 | Ayacucho FC |
14 Apr 22 | r02 | Atlético Ju | 3 - 0 | Fluminense |
14 Apr 22 | r02 | Wanderers | 1 - 1 | Metropolitan |
14 Apr 22 | r02 | Unión La Ca | 1 - 0 | Banfield |
14 Apr 22 | r02 | Sao Paulo | 2 - 0 | Everton de V |
15 Apr 22 | r02 | Lanus | 3 - 1 | Barcelona SC |
15 Apr 22 | r02 | Independient | 2 - 1 | 9 de Octubre |
15 Apr 22 | r02 | Internaciona | 1 - 1 | Guaireña FC |