03 May 22 | r04 | CA River Pla | 1 - 2 | FBC Melgar |
03 May 22 | r04 | Cuiaba | 1 - 2 | Racing Club |
04 May 22 | r04 | 9 de Octubre | 3 - 2 | Independient |
04 May 22 | r04 | Ceara | 3 - 0 | Real Esppor |
04 May 22 | r04 | General Caba | 0 - 4 | Independient |
04 May 22 | r04 | Metropolitan | 0 - 1 | Wanderers |
04 May 22 | r04 | Atletico GO | 3 - 2 | Defensa y Ju |
04 May 22 | r04 | Deportes Ant | 1 - 2 | LDU Quito |
05 May 22 | r04 | Barcelona SC | 1 - 1 | Lanus |
05 May 22 | r04 | Fluminense | 2 - 1 | Atlético Ju |
05 May 22 | r04 | Everton de V | 0 - 0 | Sao Paulo |
05 May 22 | r04 | Guaireña FC | 1 - 1 | Internaciona |
05 May 22 | r04 | Union | 2 - 0 | Oriente Petr |
06 May 22 | r04 | Banfield | 0 - 1 | Unión La Ca |
06 May 22 | r04 | Universidad | 0 - 1 | Santos FC |
06 May 22 | r04 | Ayacucho FC | 0 - 0 | Wilstermann |