18 Dec 21 | r15 | San Nicolò | 1 - 0 | Montegiorgio |
19 Dec 21 | r15 | Alma Juventu | 3 - 0 | A.S.D. Atlet |
19 Dec 21 | r15 | S.S. Chieti | 1 - 2 | Pineto |
19 Dec 21 | r15 | Vastese Calc | 1 - 0 | Trastevere |
19 Dec 21 | r15 | Sambenedette | 1 - 0 | US Tolentino |
19 Dec 21 | r15 | Castelfidard | 0 - 2 | U.S.D. Recan |
19 Dec 21 | r15 | Castelnuovo | 1 - 1 | Porto D Asco |
19 Dec 21 | r15 | Matese | 4 - 1 | Aurora Alto |
19 Dec 21 | r15 | Polisportiva | 4 - 2 | Nereto |