13 Feb 22 | r20 | Montegiorgio | 1 - 1 | U.S.D. Recan |
13 Feb 22 | r20 | US Tolentino | 1 - 0 | Trastevere |
13 Feb 22 | r20 | Sambenedette | 3 - 0 | A.S.D. Atlet |
13 Feb 22 | r20 | Castelfidard | 0 - 1 | Alma Juventu |
13 Feb 22 | r20 | S.S. Chieti | 2 - 1 | Porto D Asco |
13 Feb 22 | r20 | Matese | 3 - 1 | Polisportiva |
13 Feb 22 | r20 | Pineto | 1 - 0 | Aurora Alto |
13 Feb 22 | r20 | San Nicolò | 0 - 0 | Nereto |
13 Feb 22 | r20 | Vastese Calc | 2 - 0 | Castelnuovo |