27 Oct 21 | r16 | Real Socieda | 0 - 3 | Lobos UPNFM |
28 Oct 21 | r16 | CD Olimpia | 1 - 0 | CD Marathón |
28 Oct 21 | r16 | Real España | 4 - 1 | Honduras Pro |
28 Oct 21 | r16 | Platense Pue | 1 - 2 | CD Victoria |
28 Oct 21 | r16 | Vida | 1 - 1 | Motagua |
28 Oct 21 | r16 | CD Olimpia | 1 - 0 | CD Marathón |
21 Apr 22 | r16 | Motagua | 3 - 2 | Honduras Pro |
21 Apr 22 | r16 | Platense Pue | 1 - 0 | CD Marathón |
21 Apr 22 | r16 | Real Socieda | 0 - 1 | CD Olimpia |
21 Apr 22 | r16 | Real España | 3 - 1 | CD Victoria |
21 Apr 22 | r16 | Vida | 4 - 2 | Lobos UPNFM |