17 Sep 21 | r29 | Fernando de | 2 - 2 | Sportivo Tri |
17 Sep 21 | r29 | Independient | 0 - 2 | Tacuary |
18 Sep 21 | r29 | General Día | 0 - 2 | Sportivo Ame |
18 Sep 21 | r29 | Rubio Ñu | 0 - 0 | Sportivo Ite |
19 Sep 21 | r29 | Deportivo Ca | 0 - 0 | 2 de Mayo |
19 Sep 21 | r29 | Resistencia | 2 - 1 | Atyrá |
19 Sep 21 | r29 | Guaraní de | 1 - 0 | Fulgencio Ye |
20 Sep 21 | r29 | Deportivo Sa | 0 - 0 | General Caba |
20 Sep 21 | r29 | Club Sportiv | 0 - 1 | 3 de Febrero |