12 Nov 21 | r03 | Bibiani Gold | 0 - 1 | Asante Kotok |
13 Nov 21 | r03 | Dreams FC | 3 - 1 | Accra Lions |
13 Nov 21 | r03 | Legon Cities | 0 - 1 | Great Olympi |
14 Nov 21 | r03 | Hearts of Oa | 1 - 1 | Aduana Stars |
14 Nov 21 | r03 | Eleven Wonde | 0 - 0 | Medeama |
14 Nov 21 | r03 | Bechem Unite | 2 - 0 | Elmina Shark |
14 Nov 21 | r03 | King Faisal | 2 - 0 | Ashanti Gold |
14 Nov 21 | r03 | Karela Unite | 2 - 1 | Berekum Chel |
14 Nov 21 | r03 | Real Tamale | 2 - 0 | WAFA |