12 Feb 22 | r121 | Langreo | 3 - 0 | UD Llanera |
12 Feb 22 | r121 | Arosa | 1 - 0 | Gimnástica |
13 Feb 22 | r121 | Compostela | 1 - 0 | Leganés II |
13 Feb 22 | r121 | Real Avilés | 2 - 3 | Coruxo |
13 Feb 22 | r121 | Ceares | 0 - 3 | Marino |
13 Feb 22 | r121 | Navalcarnero | 1 - 1 | Unión Adarv |
13 Feb 22 | r121 | Cristo Atlé | 2 - 0 | CD Móstoles |
13 Feb 22 | r121 | Pontevedra | 0 - 1 | Bergantiños |
13 Feb 22 | r121 | Salamanca UD | 0 - 1 | Arenteiro |