08 Jan 22 | r18 | Real Madrid | 3 - 1 | FC Andorra |
08 Jan 22 | r18 | San Fernando | 1 - 1 | Llagostera |
08 Jan 22 | r18 | Sabadell | 3 - 1 | Linares Depo |
09 Jan 22 | r18 | Gimnastic | 0 - 0 | Albacete |
09 Jan 22 | r18 | Algeciras CF | 2 - 1 | Villarreal B |
09 Jan 22 | r18 | Sevilla Atle | 1 - 0 | Linense |
09 Jan 22 | r18 | Barcelona B | 1 - 2 | Betis Deport |
09 Jan 22 | r18 | UCAM Murcia | 2 - 0 | Cornellà |
09 Feb 22 | r18 | Alcoyano | 1 - 1 | Castellón |
23 Feb 22 | r18 | Atlético Sa | 1 - 0 | Atlético Ba |