11 Sep 21 | r22 | Mutilvera | 3 - 2 | Náxara |
11 Sep 21 | r22 | Laredo | 0 - 1 | Osasuna B |
11 Sep 21 | r22 | AD San Juan | 0 - 0 | Rayo Cantabr |
12 Sep 21 | r22 | Real Socieda | 1 - 0 | Sestao |
12 Sep 21 | r22 | Tropezón | 0 - 2 | Gernika |
12 Sep 21 | r22 | Arenas Club | 2 - 0 | Cayón |
12 Sep 21 | r22 | Racing Rioja | 2 - 0 | Ardoi |
12 Sep 21 | r22 | CD Izarra | 2 - 1 | UD Logroñé |
12 Sep 21 | r22 | Burgos Prome | 2 - 1 | Peña Sport |