09 Oct 21 | r26 | AD San Juan | 1 - 2 | UD Logroñé |
09 Oct 21 | r26 | Burgos Prome | 1 - 1 | Osasuna B |
09 Oct 21 | r26 | Ardoi | 0 - 3 | Rayo Cantabr |
09 Oct 21 | r26 | Peña Sport | 1 - 1 | Cayón |
09 Oct 21 | r26 | Real Socieda | 3 - 1 | Mutilvera |
10 Oct 21 | r26 | Laredo | 4 - 1 | CD Izarra |
10 Oct 21 | r26 | Racing Rioja | 1 - 1 | Sestao |
10 Oct 21 | r26 | Tropezón | 1 - 1 | Náxara |
10 Oct 21 | r26 | Arenas Club | 0 - 0 | Gernika |