30 Oct 21 | r06 | CSM Bucureș | 29 - 30 | Brest Bretag |
30 Oct 21 | r06 | Győri Audi | 41 - 19 | IK Sävehof |
30 Oct 21 | r06 | ŽRK Budućn | 26 - 30 | Ferencváros |
30 Oct 21 | r06 | RK Krim Wome | 26 - 27 | Vipers Krist |
31 Oct 21 | r06 | Borussia Dor | 38 - 14 | RK Podravka |
31 Oct 21 | r06 | Team Esbjerg | 25 - 18 | Rostov-Don W |
31 Oct 21 | r06 | HBC CSKA Mos | 21 - 28 | Odense Hånd |
31 Oct 21 | r06 | Kastamonu Bl | 20 - 30 | Metz Handbal |