20 Nov 21 | r08 | CSM Bucureș | 27 - 21 | Ferencváros |
20 Nov 21 | r08 | RK Krim Wome | 24 - 21 | HBC CSKA Mos |
20 Nov 21 | r08 | Rostov-Don W | 34 - 23 | RK Podravka |
20 Nov 21 | r08 | ŽRK Budućn | 30 - 28 | Brest Bretag |
20 Nov 21 | r08 | Kastamonu Bl | 22 - 38 | Győri Audi |
20 Nov 21 | r08 | Vipers Krist | 31 - 27 | Odense Hånd |
21 Nov 21 | r08 | Team Esbjerg | 34 - 24 | Borussia Dor |
21 Nov 21 | r08 | Metz Handbal | 35 - 21 | IK Sävehof |