01 May 21 | r31 | SC Heracles | 4 - 0 | VVV-Venlo |
01 May 21 | r31 | Fortuna Sitt | 3 - 0 | FC Twente |
01 May 21 | r31 | RKC Waalwijk | 1 - 3 | AZ Alkmaar |
01 May 21 | r31 | Vitesse | 2 - 1 | PEC Zwolle |
01 May 21 | r31 | FC Utrecht | 3 - 2 | Willem II |
02 May 21 | r31 | ADO Den Haag | 3 - 2 | Feyenoord |
02 May 21 | r31 | FC Groningen | 1 - 2 | Sparta |
02 May 21 | r31 | Ajax | 4 - 0 | FC Emmen |
02 May 21 | r31 | PSV Eindhove | 2 - 2 | SC Heerenvee |