07 Jan 22 | r12 | Medeama | 1 - 1 | Berekum Chel |
08 Jan 22 | r12 | Bibiani Gold | 0 - 1 | Hearts of Oa |
08 Jan 22 | r12 | Accra Lions | 0 - 0 | WAFA |
09 Jan 22 | r12 | Eleven Wonde | 2 - 0 | King Faisal |
09 Jan 22 | r12 | Dreams FC | 0 - 1 | Legon Cities |
09 Jan 22 | r12 | Great Olympi | 1 - 1 | Karela Unite |
09 Jan 22 | r12 | Elmina Shark | 0 - 1 | Aduana Stars |
09 Jan 22 | r12 | Asante Kotok | 3 - 1 | Ashanti Gold |
09 Jan 22 | r12 | Bechem Unite | 2 - 0 | Real Tamale |