19 Feb 22 | r14 | Ferencváros | 23 - 21 | Borussia Dor |
19 Feb 22 | r14 | Brest Bretag | 18 - 29 | Rostov-Don W |
19 Feb 22 | r14 | ŽRK Budućn | 27 - 21 | RK Podravka |
19 Feb 22 | r14 | Vipers Krist | 30 - 29 | Győri Audi |
20 Feb 22 | r14 | CSM Bucureș | 29 - 29 | Team Esbjerg |
20 Feb 22 | r14 | RK Krim Wome | 32 - 18 | IK Sävehof |
20 Feb 22 | r14 | HBC CSKA Mos | 27 - 26 | Metz Handbal |
20 Feb 22 | r14 | Odense Hånd | 37 - 29 | Kastamonu Bl |